Clinical trials: COVID, Coronavirus
COVID-19 Pandemic, COVID-19 Vaccines
UNAIR Inactivated COVID-19 Vaccine INAVAC as Heterologue Booster (Immunobridging Study) in Adolescent Subjects
This is an open label trial. There will only be 1 group in the study. All subjects will receive INAVAC vaccine and be followed for 6 months. The vaccine will be administered intramuscularly.
- Trial name
- NCT06272253
- Testing
- INAVAC (Vaksin Merah Putih - UA- SARS CoV-2 (Vero Cell Inactivated) 5 μg
- Where
- Indonesia
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Dr. Soetomo General Hospital
SARS-CoV-2 Infection
PHASE 1 SARS-COV-2-Spike-Ferritin-Nanoparticle (SpFN) Vaccine With ALFQ Adjuvant for Prevention of COVID-19
The purpose of this study is to evaluate the safety, reactogenicity, and immune response of the SpFN COVID-19 vaccine with Army Liposomal Formulation QS21 (ALFQ) adjuvant in healthy adults ages 18-55.
- Trial name
- NCT04784767
- Testing
- 25 µg SpFN_1B-06-PL + ALFQ (QS21 Adjuvant), Sodium chloride, USP, for injection (0.9% NaCl), 50 µg SpFN_1B-06-PL + ALFQ (QS21 Adjuvant)
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- U.S. Army Medical Research and Development Command
COVID-19
Phase I/II Clinical Trial of Recombinant Novel Coronavirus (COVID-19) Vaccine (Adenovirus Type 5 Vector) for Inhalation
This study is a randomized, double-blind, placebo-controlled I/II clinical trial, in order to evaluate the safety and immunogenicity of Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector) for Inhalation in adults 18…
- Trial name
- NCT04840992
- Testing
- Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector) for Inhalation, Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector)
- Where
- China
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- CanSino Biologics Inc.
Covid19
Communities Fighting COVID-19!
To create and evaluate effective COVID-19 testing uptake strategies that focus on underserved individuals who are exposed but have not accessed testing, and underserved individuals who are not routinely tested because they are…
- Trial name
- NCT05148936
- Testing
- COVID-19 Testing Home-based (Aim 1), COVID-19 Testing Mobile (Aim 1), COVID-19 Testing Mobile Approach 1 (Aim 2)
- Where
- United States
- Volunteers
- 32,750 people, healthy volunteers welcome
- Sponsor
- San Diego State University
COVID-19, Coronavirus Infection
Piclidenoson for Treatment of COVID-19
Patients with documented moderate COVID-19 infection will be randomized 1:1 to receive piclidenoson 2 mg Q12H orally with standard supportive care (SSC - intervention arm) or placebo orally with SSC (control arm) for up to 28…
- Trial name
- NCT04333472
- Testing
- Piclidenoson
- Where
- 6 sites in Bulgaria, Israel and 1 more
- Volunteers
- 6 people
- Sponsor
- Can-Fite BioPharma
Covid19
Study of the Safety, Reactogenicity and Immunogenicity of "EpiVacCorona" Vaccine for the Prevention of COVID-19
The aim of the clinical study is to determine the safety, reactogenicity and immunogenicity parameters of the EpiVacCorona vaccine in volunteers aged 18-60 years.
- Trial name
- EpiVacCorona (NCT04527575)
- Testing
- EpiVacCorona (EpiVacCorona vaccine based on peptide antigens for the prevention of COVID-19)
- Where
- Russia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Federal Budgetary Research Institution State Research Center of Virology and Biotechnology "Vector"
COVID-19
Mechanisms Underlying Long-term Fatigue and Exercise Intolerance Following COVID-19
The MEXICO study is an observational study that aims to identify underlying mechanisms contributing to exercise intolerance in the presence of persistent COVID-19 symptoms (Long COVID).
- Trial name
- MEXICO (NCT04914754)
- Where
- United Kingdom
- Volunteers
- 51 people
- Sponsor
- University College, London
Severe Acute Respiratory Syndrome (SARS) Pneumonia, COVID-19 Pneumonia
GM-CSF Inhalation to Prevent ARDS in COVID-19 Pneumonia
To assess the safety and tolerability of inhaled molgramostim nebuliser solution in patients with COVID-19 pneumonia.
- Trial name
- GI-COVID (NCT04569877)
- Testing
- Molgramostim nebuliser solution
- Where
- 9 sites in Germany
- Volunteers
- 63 people
- Sponsor
- University of Giessen
SARS-CoV-2 Infection, Anti-SARS-CoV-2 Infection
Registry of Sustained Immunity to COVID-19 Among ESKD Patients
This is a multi-center, prospective registry study of subjects undergoing hemodialysis for treatment of end-stage renal disease in a DaVita center.
- Trial name
- RePAiR (NCT04495764)
- Where
- 12 sites in United States
- Volunteers
- 2,315 people
- Sponsor
- Davita Clinical Research
Coronavirus Infection
STerOids in COVID-19 Study
At the time of writing (3/4/2020), close to a million people have been infected by the SARS-CoV-2 coronavirus around the world. The severe clinical condition that leads to deaths is now called CoVID-19.
- Trial name
- STOIC (NCT04416399)
- Testing
- Budesonide dry powder inhaler
- Where
- United Kingdom
- Volunteers
- 146 people
- Sponsor
- University of Oxford
COVID-19 Respiratory Infection, SARS-CoV2 Infection
Echinaforce COVID-19 Shedding Study
Respiratory viruses pose a permanent threat to humans and society as demonstrated by the current Covid-19 pandemic. Novel drugs and vaccines provide a means for controlling illness.
- Trial name
- NCT04999098
- Testing
- Echinaforce Forte tablets, Echinaforce Chewable tablets, Echinaforce tincture
- Where
- Bulgaria
- Volunteers
- 40 people
- Sponsor
- A. Vogel AG
COVID-19
COVID-19 Antithrombotic Rivaroxaban Evaluation
There are several ways in which the COVID-19 pandemic may affect the prevention and management of thrombotic and thromboembolic disease, either direct effect or the indirect effects of infection, such as through severe illness…
- Trial name
- CARE (NCT04757857)
- Testing
- Rivaroxaban 10 mg
- Where
- 36 sites in Brazil
- Volunteers
- 660 people
- Sponsor
- Hospital Alemão Oswaldo Cruz
SARS CoV 2 Infection, Muscle Disorder
Eficacia Ventilatoria y Remolacha
The lung is the organ most affected by COVID-19. There are patients who successfully overcome the acute COVID-19 infection and their lungs return to a normal state.
- Conditions
- SARS CoV 2 Infection, Muscle Disorder, Fatigue
- Trial name
- NCT06217211
- Testing
- Remolacha
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Hospital de Mataró
SARS-CoV-2 Infection, Influenza
Household Study of COVID-19, Influenza and RSV Burden, Transmission Dynamics and Viral Interaction in South Africa
The study aims to characterize the community burden (including the clinical features) and transmissibility of SARS-CoV-2 within the context of a functional antibody response.
- Conditions
- SARS-CoV-2 Infection, Influenza, Respiratory Syncytial Virus (RSV)
- Trial name
- PHIRST-C (NCT05277298)
- Where
- 2 sites in South Africa
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- National Institute for Communicable Diseases, South Africa
COVID-19, Corona Virus Infection
Hydroxychloroquine in Patients With Newly Diagnosed COVID-19 Compared to Standard of Care
This study will assess the efficacy of hydroxychloroquine in reducing the severity of symptoms in patients with COVID-19
- Conditions
- COVID-19, Corona Virus Infection, SARS-CoV-2, 2019-nCoV
- Trial name
- NCT04334967
- Testing
- Hydroxychloroquine, Vitamin C
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Providence Health & Services
Covid19, Vaccine Reaction
Post COVID-19 Vaccination Analysis in Healthcare Worker Recipients
This research study is studying how healthcare worker recipients react after receiving vaccinations for COVID-19. The objective of the study is to evaluate the immune response to COVID-19 vaccination.
- Trial name
- NCT04922944
- Testing
- COVID-19 vaccine
- Where
- United States
- Volunteers
- 167 people
- Sponsor
- Huntington Memorial Hospital
COVID-19, SARS-CoV-2 Infection
Evaluation of the Efficacy and Safety of Molnupiravir Treatment in Mild/Moderate Covid-19 Patients.
Evaluation of the Efficacy and Safety of Molnupiravir Treatment in Mild/Moderate Covid-19 Patients. Turkey Cohort, Prospective, Observational, Comparative Study In the antiviral treatment of COVID-19, molnupiravir, an RdRp…
- Trial name
- NCT06223932
- Testing
- Molnupiravir
- Where
- 8 sites in Turkey (Türkiye)
- Volunteers
- 2,600 people
- Sponsor
- Serap Yavuz
Covid19
COVID-19 International Drug Pregnancy Registry
The objective of the COVID-19 International Drug Pregnancy Registry (COVID-PR) is to evaluate obstetric, neonatal, and infant outcomes among women treated with monoclonal antibodies or antiviral drugs indicated for mild…
- Trial name
- COVID-PR (NCT05013632)
- Testing
- Antiviral Agents, Monoclonal antibody
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- Pregistry
COVID-19
Impact of COVID-19 Outbreak on Non-COVID-19 Patients
The Geneva Canton organized the health crisis of the COVID-19 epidemic around the care of COVID patients at the University Hospital (HUG), by moving the care of non-COVID patients to private hospitals of the canton.
- Trial name
- NoCOVImpact (NCT04537559)
- Where
- Switzerland
- Volunteers
- 240,000 people
- Sponsor
- University Hospital, Geneva
COVID-19
Safety and Serum Virus Neutralizing Antibody Responses of VYD2311, a COVID-19 Vaccine, and Coadministered VYD2311 With a COVID-19 Vaccine
The main purposes of this research study are to measure the safety (whether it causes any side effects), tolerability (if it does cause any side effects, how well your body is able to handle them), and reactions, both local at…
- Trial name
- LIBERTY (NCT07655180)
- Testing
- COVID-19 mRNA vaccine, VYD2311
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Invivyd, Inc.
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