Clinical trials: COVID
SARS-CoV2 Infection
Receptive Music Therapy on Anxiety and Vital Parameters in Hospitalized Covid-19 Patients.
Hospitalized patients for Covid-19 are extremely isolated from their families for a long and uncertain period of time .This traumatic separation makes patients vulnerable to different degrees of stress disorders as well as…
- Trial name
- MADC-19 (NCT05077306)
- Testing
- music therapy group
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Post-COVID ME/CFS
Hyperbaric High Pressure Oxygen Therapy in Post-COVID Syndrome and ME/CFS
The objective of this observational study is to document symptom progression in 60 patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) who undergo Hyperbaric Oxygen Therapy (HBOT) following COVID or other…
- Trial name
- NCT06118138
- Testing
- Hyperbaric oxygen therapy (HBOT)
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Charite University, Berlin, Germany
Coronavirus Infections, Vaccine
This is a Double-blind, Placebo-controlled, Randomized Study of the Tolerability, Safety and Immunogenicity of an Inactivated Whole Virion Concentrated Purified Vaccine (CoviVac) Against Covid-19
Randomized, double-blind, placebo controlled, multi-center clinical trials of the tolerability, safety and immunogenicity of the inactivated whole-virion concentrated purified vaccine against COVID-19, manufactured by FSBSI…
- Trial name
- NCT05046548
- Testing
- Vaccine for intramuscular injection
- Where
- 5 sites in Russia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Chumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products
COVID
Indirect Endovenous Systemic Ozone for New Coronavirus Disease (COVID19) in Non-intubated Patients
Systemic medical ozone has proved to help in several viral diseases, chronic obstructive pulmonary disease and chronic inflammation process.
- Trial name
- OzonoCOVID19 (NCT04359303)
- Testing
- Systemic indirect endovenous ozone therapy
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Javier Hidalgo Tallón
Posttraumatic Stress Disorder, Covid19
Efficacy of TBCT, MBHP and PPT for PTSD During the Covid-19 Pandemics
The psychotherapies to be assessed in the present study, delivered on-line, are: trial-based cognitive therapy (TBCT), mindfulness-based health promotion (MBHP), and positive psychotherapy (PPT).
- Trial name
- NCT04852770
- Testing
- Trial-Based Cognitive Therapy, Mindfulness-Based Health Promotion, Positive psychotherapy
- Where
- 3 sites in Brazil
- Volunteers
- 135 people
- Sponsor
- Fundação Bahiana de Infectologia
SARS-CoV-2 Rapid Antigen Test
Rapid Antigen Testing for SARS-CoV-2 Among Healthcare Workers to Prevent Spread of COVID-19
Physicians, nurses and hospital attendants currently working at the University Clinic of Respiratory and Allergic Diseases Golnik were invited to participate in the pilot study.
- Trial name
- NCT04716088
- Testing
- Rapid antigen test for SARS CoV2
- Where
- Slovenia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- The University Clinic of Pulmonary and Allergic Diseases Golnik
SARS-CoV-2 Infection
This is a Phase 1 Study to Evaluate the Safety,Tolerability and Virology of CT P59 in Patients With Mild Symptoms of Symptoms of Coronavirus Disease (COVID-19)
This is a Phase I study that randomized, double-blind, Placebo-controlled, Parallel Group, Single Ascending Dose Study to evaluate Safety, Tolerability and Virology of CT-P59 in Patient with Mild Symptoms of Severe Acute…
- Trial name
- NCT04593641
- Testing
- CT-P59
- Where
- South Korea
- Volunteers
- 18 people
- Sponsor
- Celltrion
SARS-CoV-2 Infection
COVID-19 Omicron BA.5 Subvariant Dose Finding Infection Study
A phase 1, dose-finding open label clinical infection, safety and viral detection optimization in healthy volunteers immunologically experienced against SARS-CoV-2.
- Trial name
- NCT06478420
- Testing
- Omicron BA.5 SARS-CoV-2 challenge virus
- Where
- United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Oxford
To Assess the Reduction in the Viral Load of SARS-CoV-2 in Patients Receiving Ivermectin Compared to Those Receiving Standard Care
Evaluation of the Impact of the Administration of Single Dose of Ivermectin in the Early Phase of COVID-19
The action of ivermectin in vitro on the viral replication of SARS-CoV-2 was demonstrated and published by an Australian team in June 2020.
- Trial name
- IVERCoV (NCT05040724)
- Testing
- Ivermectin
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Raincy Montfermeil Hospital Group
COVID, Corona Virus Infection
Novel Regimens in COVID-19 Treatment
Nitazoxanide has been shown to have a clinical efficacy against severe acute respiratory syndrome coronavirus 2; ivermectin has also demonstrated a remarkable experimental efficacy with a potential to be used for Coronavirus…
- Trial name
- NCT04382846
- Testing
- Nitazoxanide
- Where
- 2 sites in Egypt
- Volunteers
- 160 people
- Sponsor
- Tanta University
Diabetes Mellitus, SARS-CoV-2
Anxiety, Depression and Eating Attitudes of Diabetes Mellitus Patients During COVID-19 Lockdown in Greece
The aim of this observational, cross-sectional study is to evaluate the impact of the second national COVID-19 lockdown in Greece, regarding the aspects of depression, anxiety and eating habits, in relation to the adjusted work…
- Trial name
- NCT04700254
- Testing
- DASS questionnaire, EAT-26 questionnaire
- Where
- Greece
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Chania General Hospital "St. George"
Covid19
Viral Clearance, PK and Tolerability of Ensovibep in COVID-19 Patients
This study will investigate how ensovibep is distributed throughout the body, the viral clearance and the tolerability of ensovibep in patients with symptomatic COVID-19 disease
- Trial name
- NCT04834856
- Testing
- ensovibep
- Where
- Netherlands
- Volunteers
- 12 people
- Sponsor
- Molecular Partners AG
COVID-19 Prevention
An Open Study on the Safety, Tolerability, and Immunogenicity of "Sputnik Light" Vaccine
Phase I-II open prospective, two-stage, non-randomized study in healthy volunteers.
- Trial name
- NCT04713488
- Testing
- Sputnik Light
- Where
- Russia
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation
COVID19
SARS-CoV-2 (COVID-19) Detection Using the Breath Analizer TeraSystem
The purpose of the study is to verify the sensibility and accuracy of a rapid detection test for SARS-CoV-2 in breath samples analyzed by the breath detector analyzer TeraSystem, comparing with PCR tests.
- Trial name
- NCT04497610
- Testing
- Breath sample
- Where
- Costa Rica
- Volunteers
- healthy volunteers welcome
- Sponsor
- Instituto Costarricense de Investigaciones Clínicas ICIC
COVID
Maraviroc in Patients With Moderate and Severe COVID-19
Maraviroc, a C-C Chemokine Receptor 5 (CCR5) antagonist, is well-tolerated without significant side effects in its current use in patients with HIV.
- Trial name
- NCT04435522
- Testing
- Maraviroc
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Rhode Island Hospital
COVID 19
Use of the Nasal Cannula During COVID-19
The objective of this investigation is to determine the incidence of the use of the low flow nasal cannula in suspected or confirmed cases with Covid-19
- Trial name
- NCT04376580
- Where
- Argentina
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tiva Group
Mechanical Ventilation, Sedation
Propranolol as an Anxiolytic to Reduce the Use of Sedatives From Critically-ill Adults Receiving Mechanical Ventilation
The COVID-19 pandemic has led to shortages of intravenous sedatives due to increased ICU patient admissions and greater use of mechanical ventilation.
- Conditions
- Mechanical Ventilation, Sedation, Critical Illness, COVID
- Trial name
- PROACTIVE (NCT04467086)
- Testing
- Propranolol Hydrochloride
- Where
- 2 sites in Canada
- Volunteers
- 72 people
- Sponsor
- Ottawa Hospital Research Institute
Novel Coronavirus Infection
Lopinavir/ Ritonavir, Ribavirin and IFN-beta Combination for nCoV Treatment
A combination of lopinavir/ ritonavir, ribavirin and interferon beta-1b will expedite the recovery, suppress the viral load, shorten hospitalisation and reduce mortality in patients with 2019-n-CoV infection compared with to…
- Trial name
- NCT04276688
- Testing
- Lopinavir/ritonavir, Ribavirin, Interferon Beta-1B
- Where
- Hong Kong
- Volunteers
- 127 people
- Sponsor
- The University of Hong Kong
Covid19
Respiratory Tele Monitoring COVID 19 (TMR COVID-19)
The determinants of the evolution to a severe form for COVID-19 pneumonia remain unclear. COVID-19 pneumonia is characterized by a hypoxemia with a possible rapid worsening and related resuscitation requirement.
- Trial name
- NCT04821973
- Testing
- Radius PPG Tetherless Pulse Oximetry (Masimo), usual monitoring
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
COVID-19
Immunogenicity and Safety of Booster Immunization of ZF2001 After Inoculation With Two Doses of BBIBP-CorV
Study objectives: To evaluate the immunogenicity and immunity persistence and safety of recombinant novel coronavirus vaccine (CHO cells) after booster immunization in populations vaccinated with two doses of marketed novel…
- Trial name
- NCT05205083
- Testing
- Recombinant novel coronavirus vaccine (CHO cells)
- Where
- China
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.