Clinical trials: COVID-19, SARS-CoV-2
Covid19
COVID-19 Seroconversion Study Among GHdC Staff Members - Summer 2020
The management of the Grand Hôpital de Charleroi hospital authorized the performance of a serology for each member of the establishment's staff in order to better characterize the proportion of its employees who have already been…
- Trial name
- NCT04723290
- Testing
- Serological tests for SARS Cov-2
- Where
- Belgium
- Volunteers
- 2,817 people, healthy volunteers welcome
- Sponsor
- Grand Hôpital de Charleroi
SARS CoV 2 Infection
Rutgers Pilot for PREDICT- Patient POC Test
A pilot study was initiated to assess feasibility of testing asymptomatic dental patients presenting to the Oral Medicine Clinic at Rutgers School of Dental Medicine for SARS-CoV-2 viral antigen using a point-of-care (POC) Rapid…
- Trial name
- NCT05612724
- Testing
- Testing for SARS CoV2 Antigen
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Covid19
Cluster-Randomized Trial of Air Filtration and Ventilation to Reduce Covid19 Spread in Homes
Investigators are evaluating whether an intervention consisting of box-fans with MERV 16 filters ("filtration fans") and recommendations for improving ventilation in the home can reduce secondary spread of Covid19 from an index…
- Trial name
- NCT05777720
- Testing
- Filtration Fan, Safe-home pamphlet, Mid-week phone call
- Where
- 2 sites in United States
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Stanford University
To Assess the Reduction in the Viral Load of SARS-CoV-2 in Patients Receiving Ivermectin Compared to Those Receiving Standard Care
Evaluation of the Impact of the Administration of Single Dose of Ivermectin in the Early Phase of COVID-19
The action of ivermectin in vitro on the viral replication of SARS-CoV-2 was demonstrated and published by an Australian team in June 2020.
- Trial name
- IVERCoV (NCT05040724)
- Testing
- Ivermectin
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Raincy Montfermeil Hospital Group
Sars-CoV2, COVID19
A Study of Hydroxychloroquine and Zinc in the Prevention of COVID-19 Infection in Military Healthcare Workers
A multicenter randomized clinical trial aiming to assess the efficacy of hydroxychloroquine associated to Zinc compared to hydroxychloroquine, in the prevention of Military Health Professionals Exposed to SARS CoV2 in Tunisia
- Trial name
- COVID-Milit (NCT04377646)
- Testing
- Hydroxychloroquine, Zinc
- Where
- Tunisia
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- Military Hospital of Tunis
Post-Acute COVID-19 Syndrome, Irritable Bowel Syndrome
Effect of Lecithin-based Curcuma and Boswellia on Post-acute COVID-19 IBS
This open-label study investigates the effects of lecithin-based formulations of Curcuma longa (Meriva™) and Boswellia serrata (Casperome™) extracts on post-acute COVID-19 irritable bowel syndrome (PCIBS) and irritable bowel…
- Conditions
- Post-Acute COVID-19 Syndrome, Irritable Bowel Syndrome, Abdominal Pain, Dysbiosis
- Trial name
- NCT06423586
- Testing
- Curcuma longa and Boswellia serrata extracts
- Where
- Italy
- Volunteers
- 44 people
- Sponsor
- Azienda di Servizi alla Persona di Pavia
Coronavirus Infection, Prevalence
Epidemiological Study of Seroprevalence Against the SARS-CoV-2 Virus (COVID-19)
In order to inform the public decision on the containment strategy and knowledge of the intensity of the epidemic during post-containment, estimates of the share of the population infected with the SARS-CoV-2 virus responsible…
- Trial name
- COVAL-NANCY (NCT04448769)
- Testing
- Anti-SARS-CoV-2 IgT seropositivity
- Where
- France
- Volunteers
- 2,006 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
SARS CoV 2 Infection, Influenza, Human
A Phase II Trial to Evaluate the Safety and Immunogenicity of BIMERVAX® When Coadministered With Seasonal Influenza Vaccine (SIIV) in Adults Older Than 65 Years of Age Fully Vaccinated Against COVID-19
This is a Phase II, randomized, double-blind, multi-centre trial to evaluate the safety and immunogenicity of BIMERVAX® when coadministered with seasonal surface antigen inactivated adjuvanted influenza vaccine (SIIV) in adults…
- Trial name
- NCT05981846
- Testing
- BIMERVAX, SIIV
- Where
- 8 sites in Spain
- Volunteers
- 279 people, healthy volunteers welcome
- Sponsor
- Hipra Scientific, S.L.U
SARS-CoV-2 Infection, Covid19
Burden of COVID-19 Infection in Populations With High or Low Risk of Infection
Introduction. Some issues remain to be elucidated about SARS-CoV-2 infection to plan prevention interventions based on scientific evidence, such as the actual prevalence of infection including subclinical and seroconverted cases…
- Trial name
- NCT04636203
- Where
- 2 sites in Italy
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Neuromed IRCCS
Healthy
A Study to Assess the Safety, Tolerability, and Pharmacokinetics of HFB30132A Against COVID-19 in Chinese Healthy Adults
The purpose of this study is to examine the safety and tolerability of HFB30132A when it is given by single intravenous infusion in Chinese healthy participants.
- Trial name
- NCT05275660
- Testing
- HFB30132A
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- HiFiBiO Therapeutics
COVID-19 Pneumonia, Sepsis
Retrospective Analysis of Chest X-ray Severity Scoring System of COVID-19 Pneumonia
The research will be retrospective, and will include all patients who were admitted during 2020 and 2021 in the COVID-19 ICU of University Hospital Center Osijek due to pneumonia caused by the Severe acute respiratory syndrome…
- Conditions
- COVID-19 Pneumonia, Sepsis, SARS-CoV-2 Acute Respiratory Disease, Pneumonia
- Trial name
- RANCH-COVID (NCT05181696)
- Testing
- Chest X-ray
- Where
- Croatia
- Volunteers
- 200 people
- Sponsor
- Osijek University Hospital
COVID-19
The LUSZ COVID-19 Severity Index: A Prognostic and Predictive Score of Mortality for Hospitalized Patients With Covid-19
The coronavirus disease 2019 (COVID-19) has spread rapidly and caused a global pandemic, as defined by the WHO, within a short period of time.
- Trial name
- LUSZ_SCORE (NCT05848427)
- Testing
- LUSZ P
- Where
- 2 sites in Lebanon
- Volunteers
- 1,000 people
- Sponsor
- Lebanese University
Severe Acute Respiratory Syndrome Coronavirus 2, Hypoxemic Respiratory Failure
COVIDNOCHE Trial (HFNO Versus CPAP Helmet) in COVID-19 Pneumonia
The purpose of the COVIDNOCHE trial (HFNO versus CPAP Helmet Evaluation in COVID-19 Pneumonia) is to evaluate the comparative effectiveness of standard care non-invasive respiratory support (helmet CPAP versus HFNO) for acute…
- Conditions
- Severe Acute Respiratory Syndrome Coronavirus 2, Hypoxemic Respiratory Failure, Pneumonia, Viral, COVID
- Trial name
- COVIDNOCHE (NCT04381923)
- Testing
- Helmet Continuous Positive Airway Pressure (CPAP), High Flow Nasal Oxygen (HFNO)
- Where
- United States
- Sponsor
- University of Pennsylvania
COVID-19 Infection, Cancer Patients
COVID19-Convalescent Plasma for Treating Patients With Active Symptomatic COVID 19 Infection (FALP-COVID)
COVID-19 infection has spread worldwide causing several deaths in few months Convalescent Plasma from COVID 19 donors has shown huge activity in small series from Chinese patients and currently many centers from USA and the…
- Conditions
- COVID-19 Infection, Cancer Patients, General Population
- Trial name
- FALP-COVID (NCT04384588)
- Testing
- Convalescent Plasma from COVID-19 donors
- Where
- Chile
- Volunteers
- 100 people
- Sponsor
- Fundacion Arturo Lopez Perez
COVID-19
Plasma Immunity of Mild SARS-CoV-2 Omicron and Delta Pandemic in Thailand
The investigators assessed the effect of treatment for COVID and immunity of the volunteers who admitted to the home isolation.
- Trial name
- NCT05328479
- Where
- Thailand
- Volunteers
- 5,181 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Long-COVID, Brain Fog
Effect of Daily Walnut Consumption on Memory in Subjects With Long-COVID
Approximately 30% of patients experience "Long-COVID" syndrome presenting with symptoms such as cognitive difficulties ('brain fog'), fatigue, dyspnea, autonomic dysfunction, depression and anxiety, lasting beyond 12 weeks…
- Conditions
- Long-COVID, Brain Fog, Cognition, Memory
- Trial name
- NCT07429903
- Testing
- whole food - walnuts
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of California, Los Angeles
Myocarditis, Pediatric Inflammatory Multisystem Syndrome
Multiparametric Echocardiography and Cardiac Biomarkers in Pediatric Inflammatory Heart Diseases
Acquired inflammatory or infectious cardiac diseases, in pediatrics, include Kawasaki disease, myocarditis, and Covid-19-related Pediatric Multisystemic Inflammatory Syndrome (PIMS).
- Conditions
- Myocarditis, Pediatric Inflammatory Multisystem Syndrome, Kawasaki Disease
- Trial name
- NCT05911386
- Testing
- study of biological samples and echocardiographic data and link with need of hemodynamic support
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Central Hospital, Nancy, France
Healthy Older Adults Ages 60-89
Longitudinal Innate Immunity and Aging Study
This study plans to examine biological bases of cognitive aging. The goals of the study are to better understand how immune system markers, measured in the blood and in the spinal fluid, are related to clinical features of aging…
- Trial name
- LIIA (NCT03944603)
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
COVID 19
Neuropathology in Adults Intensive Care Unit Patients With COVID 19
This is a single center observational autopsy study, conducted during the first wave of the coronavirus disease (COVID-19) pandemic in France.
- Trial name
- NCT04453670
- Testing
- autopsy
- Where
- France
- Volunteers
- 7 people
- Sponsor
- University of Versailles
Long COVID Syndrome
A Fasting Pilot Study for Long COVID
Background Long COVID (LC) is a chronic multisystemic condition which substantially impact the quality of life. Despite the staggering burden of LC, there is still no effective treatment.
- Trial name
- NCT07418567
- Testing
- prolonged fasting
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Université de Sherbrooke
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