Clinical trials: COVID-19 Disease
COVID-19, Coronavirus Infection
Relative Bioavailability Study of CX2101A for the Treatment of COVID-19
The study comprises three parts: single ascending dose (SAD) studies of CX2101A tablets at 40 mg, 100 mg, and 160 mg; a relative bioavailability (BA) study comparing single-dose administration of 100 mg CX2101A tablets and…
- Trial name
- NCT06864182
- Testing
- CX2101A tablet, CX2101A enteric-coated tablet
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Heronova Pharmaceuticals
Sars-CoV2, COVID19
A Study of Hydroxychloroquine and Zinc in the Prevention of COVID-19 Infection in Military Healthcare Workers
A multicenter randomized clinical trial aiming to assess the efficacy of hydroxychloroquine associated to Zinc compared to hydroxychloroquine, in the prevention of Military Health Professionals Exposed to SARS CoV2 in Tunisia
- Trial name
- COVID-Milit (NCT04377646)
- Testing
- Hydroxychloroquine, Zinc
- Where
- Tunisia
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- Military Hospital of Tunis
Post-Acute COVID-19 Syndrome, Irritable Bowel Syndrome
Effect of Lecithin-based Curcuma and Boswellia on Post-acute COVID-19 IBS
This open-label study investigates the effects of lecithin-based formulations of Curcuma longa (Meriva™) and Boswellia serrata (Casperome™) extracts on post-acute COVID-19 irritable bowel syndrome (PCIBS) and irritable bowel…
- Conditions
- Post-Acute COVID-19 Syndrome, Irritable Bowel Syndrome, Abdominal Pain, Dysbiosis
- Trial name
- NCT06423586
- Testing
- Curcuma longa and Boswellia serrata extracts
- Where
- Italy
- Volunteers
- 44 people
- Sponsor
- Azienda di Servizi alla Persona di Pavia
Coronavirus Infection, Prevalence
Epidemiological Study of Seroprevalence Against the SARS-CoV-2 Virus (COVID-19)
In order to inform the public decision on the containment strategy and knowledge of the intensity of the epidemic during post-containment, estimates of the share of the population infected with the SARS-CoV-2 virus responsible…
- Trial name
- COVAL-NANCY (NCT04448769)
- Testing
- Anti-SARS-CoV-2 IgT seropositivity
- Where
- France
- Volunteers
- 2,006 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Dementia
Improving Wellbeing and Health for Care Home Residents During COVID-19
More than 400,000 people in the UK live in care homes. These individuals are particularly vulnerable to COVID-19; many are frail and the majority have concurrent physical health problems and dementia.
- Trial name
- COVIDWHELD (NCT04590469)
- Testing
- COVID WHELD
- Where
- United Kingdom
- Sponsor
- University of Exeter
Covid19, Muscle Loss
The Impact of Covid-19 on Skeletal Muscle
With the recent worldwide outbreak of the COVID-19 infection and the huge impact it has had upon lives in the UK, it is key to increase knowledge on the impact of the virus on the body.
- Conditions
- Covid19, Muscle Loss, Mitochondrial Alteration
- Trial name
- NCT04756674
- Testing
- No intervetion will be used
- Where
- United Kingdom
- Sponsor
- University of Nottingham
SARS CoV 2 Infection, Influenza, Human
A Phase II Trial to Evaluate the Safety and Immunogenicity of BIMERVAX® When Coadministered With Seasonal Influenza Vaccine (SIIV) in Adults Older Than 65 Years of Age Fully Vaccinated Against COVID-19
This is a Phase II, randomized, double-blind, multi-centre trial to evaluate the safety and immunogenicity of BIMERVAX® when coadministered with seasonal surface antigen inactivated adjuvanted influenza vaccine (SIIV) in adults…
- Trial name
- NCT05981846
- Testing
- BIMERVAX, SIIV
- Where
- 8 sites in Spain
- Volunteers
- 279 people, healthy volunteers welcome
- Sponsor
- Hipra Scientific, S.L.U
SARS-CoV-2 Infection, Covid19
Burden of COVID-19 Infection in Populations With High or Low Risk of Infection
Introduction. Some issues remain to be elucidated about SARS-CoV-2 infection to plan prevention interventions based on scientific evidence, such as the actual prevalence of infection including subclinical and seroconverted cases…
- Trial name
- NCT04636203
- Where
- 2 sites in Italy
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Neuromed IRCCS
Diabetes, Covid-19
Remote Continues Glucose Monitoring During the COVID-19 Pandemic in Quarantined Hospitalized Patients
This is a randomized controlled trial of isolated patients with diabetes admitted to Nordsjællands Hospital with or without COVID-19-pneumonia.
- Conditions
- Diabetes, Covid-19, Infection
- Trial name
- CGM-ISO (NCT04430608)
- Testing
- Dexcom G6
- Where
- Denmark
- Volunteers
- 64 people
- Sponsor
- Nordsjaellands Hospital
Telerehabilitation, Elderly People
The Effectiveness of Telerehabilitation-Based Exercises in Elderly People
An epidemic of pneumonia , which is thought to have developed due to a new coronavirus, was detected in Wuhan, Hubei Province of the People's Republic of China, and this epidemic could not be brought under control, leading to…
- Conditions
- Telerehabilitation, Elderly People, Social Isolation
- Trial name
- NCT04346940
- Testing
- Telerehabilitation, Exercise brochure
- Volunteers
- 30 people
- Sponsor
- Istinye University
COVID-19, AMS-H-03
Hydrogen-Oxygen Generator With Nebulizer for Rehabilitation Treatment of COVID-19
This is a prospective, multicenter, randomized, controlled, superiority clinical trial, with the test group expected to be superior to the control group in the primary evaluation endpoints (changes in Borg score and PSQI index at…
- Conditions
- COVID-19, AMS-H-03, Hydrogen-oxygen Gas
- Trial name
- NCT05504460
- Testing
- Hydrogen-Oxygen Generator with Nebulizer, AMS-H-03, basic treatment
- Where
- China
- Volunteers
- 216 people
- Sponsor
- Shanghai Zhongshan Hospital
Covid19, Vitamin D Deficiency
High Dose Vitamin-D Substitution in Patients With COVID-19: a Randomized Controlled, Multi Center Study
The world is currently facing a pandemic with the coronavirus (SARS-CoV-2) which leads to the disease of COVID-19. Risk factors for a poor outcome of COVID-19 have so far been identified as older age and co-morbidity including…
- Conditions
- Covid19, Vitamin D Deficiency, Corona Virus Infection, ARDS
- Trial name
- VitCov (NCT04525820)
- Testing
- Single high dose vitamin D, Treatment as usual vitamin D
- Where
- 2 sites in Switzerland
- Volunteers
- 80 people
- Sponsor
- Prof. Dr. Jörg Leuppi
COVID-19 Pneumonia, Sepsis
Retrospective Analysis of Chest X-ray Severity Scoring System of COVID-19 Pneumonia
The research will be retrospective, and will include all patients who were admitted during 2020 and 2021 in the COVID-19 ICU of University Hospital Center Osijek due to pneumonia caused by the Severe acute respiratory syndrome…
- Conditions
- COVID-19 Pneumonia, Sepsis, SARS-CoV-2 Acute Respiratory Disease, Pneumonia
- Trial name
- RANCH-COVID (NCT05181696)
- Testing
- Chest X-ray
- Where
- Croatia
- Volunteers
- 200 people
- Sponsor
- Osijek University Hospital
COVID-19
The LUSZ COVID-19 Severity Index: A Prognostic and Predictive Score of Mortality for Hospitalized Patients With Covid-19
The coronavirus disease 2019 (COVID-19) has spread rapidly and caused a global pandemic, as defined by the WHO, within a short period of time.
- Trial name
- LUSZ_SCORE (NCT05848427)
- Testing
- LUSZ P
- Where
- 2 sites in Lebanon
- Volunteers
- 1,000 people
- Sponsor
- Lebanese University
Rheumatic Diseases
The COVID-19 VaccinE Response and Co-Administration in Rheumatology Patients (COVER-CoAd)
Based on the experience with influenza, pneumococcal, and shingles vaccinations in rheumatic disease populations, it is clear that some disease modifying anti-rheumatic drugs and the immunomodulatory therapies used to treat…
- Trial name
- NCT05543642
- Testing
- Hepatitis A vaccine, Diphtheria, pertussis, and tetanus booster vaccine
- Where
- 7 sites in United States
- Volunteers
- 129 people
- Sponsor
- Oregon Health and Science University
Covid19, Burnout, Professional
Burnout, Stress and Coping Strategies: Impact of the Covid-19 Epidemic
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a novel coronavirus detected in Wuhan, China on December 2019. This virus is responsible for the infectious respiratory disease called Covid-19.
- Trial name
- Au20-15 (NCT04834882)
- Testing
- Data collection (
- Where
- France
- Volunteers
- 649 people
- Sponsor
- CHU de Reims
Severe Acute Respiratory Syndrome Coronavirus 2, Hypoxemic Respiratory Failure
COVIDNOCHE Trial (HFNO Versus CPAP Helmet) in COVID-19 Pneumonia
The purpose of the COVIDNOCHE trial (HFNO versus CPAP Helmet Evaluation in COVID-19 Pneumonia) is to evaluate the comparative effectiveness of standard care non-invasive respiratory support (helmet CPAP versus HFNO) for acute…
- Conditions
- Severe Acute Respiratory Syndrome Coronavirus 2, Hypoxemic Respiratory Failure, Pneumonia, Viral, COVID
- Trial name
- COVIDNOCHE (NCT04381923)
- Testing
- Helmet Continuous Positive Airway Pressure (CPAP), High Flow Nasal Oxygen (HFNO)
- Where
- United States
- Sponsor
- University of Pennsylvania
Rheumatologic Disease, Autoimmune Diseases
Testimonials and Navigation in Rheumatology
The overall goal of this study is to determine whether a novel, multi-modal, patient-directed behavioral intervention initiated in rheumatology clinics is an effective approach to improve uptake of updated COVID-19 vaccine.
- Trial name
- TANGO (NCT06469788)
- Testing
- Video comprised of AIRD patient narratives on COVID-19 vaccination thoughts and experiences, Video on the importance of good oral health for patients with AIRD, Brochure on COVID-19 vaccination in AIRD patients
- Where
- 4 sites in United States
- Volunteers
- 1,170 people
- Sponsor
- University of Alabama at Birmingham
COVID-19 Infection, Cancer Patients
COVID19-Convalescent Plasma for Treating Patients With Active Symptomatic COVID 19 Infection (FALP-COVID)
COVID-19 infection has spread worldwide causing several deaths in few months Convalescent Plasma from COVID 19 donors has shown huge activity in small series from Chinese patients and currently many centers from USA and the…
- Conditions
- COVID-19 Infection, Cancer Patients, General Population
- Trial name
- FALP-COVID (NCT04384588)
- Testing
- Convalescent Plasma from COVID-19 donors
- Where
- Chile
- Volunteers
- 100 people
- Sponsor
- Fundacion Arturo Lopez Perez
COVID-19 Pandemic, Health Knowledge, Attitudes, Practice
Baby2Home (B2H) Mobile Health Application
The COVID-19 pandemic has transformed healthcare delivery; arguably, the fields of obstetrics and pediatrics have experienced some of the greatest changes as they have transitioned away from their role as a medical home and into…
- Conditions
- COVID-19 Pandemic, Health Knowledge, Attitudes, Practice, Perinatal Depression, Mental Health Wellness
- Trial name
- NCT05595486
- Testing
- Baby2Home Mobile Application
- Where
- 2 sites in United States
- Volunteers
- 642 people
- Sponsor
- Women and Infants Hospital of Rhode Island
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