Clinical trials: COVID-19 Disease
Intellectual Disability, Developmental Disability
Best Practices to Prevent COVID-19 Illness in Staff and People With Serious Mental Illness and Developmental Disabilities in Congregate Living Settings
Best Practices to Prevent COVID-19 Illness in Staff and People With Serious Mental Illness and Developmental Disabilities in Congregate Living Settings is a research study aimed at developing, implementing, and evaluating a…
- Conditions
- Intellectual Disability, Developmental Disability, Axis I Diagnosis, Mental Illness
- Trial name
- NCT04726371
- Testing
- Generic Best Practices, Tailored Best Practices
- Where
- United States
- Volunteers
- 415 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Covid19
Comparison of Remdesivir Versus Lopinavir/ Ritonavir and Remdesivir Combination in COVID-19 Patients
Comparison outcomes of a large cohort of moderate and severe COVID-19 patients received remdesivir alone with patients who received remdesivir in combination with lopinavir/ ritonavir in addition to standard management.
- Trial name
- NCT04738045
- Testing
- Remdesivir, Lopinavir/ Ritonavir and Remdesivir combination
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ahmed Essam
Covid19
Intramuscular and Intravenous VIR-7831 (Sotrovimab) for Mild/Moderate COVID-19.
The COMET-TAIL main study evaluated efficacy, safety, and tolerability of IM sotrovimab versus IV sotrovimab in high-risk patients for the treatment of mild/moderate COVID-19.
- Trial name
- NCT04913675
- Testing
- sotrovimab
- Where
- 50 sites in United States, France and 1 more
- Volunteers
- 1,065 people
- Sponsor
- Vir Biotechnology, Inc.
COVID-19, Cognitive Decline
Study of Epidemiologic Investigation and Mechanism of Brain Network of Otologic and Cognitive Function With Post-COVID-19
The purpose of this study was to analysis the incidence of ear symptoms, cognitive function decline and emotional disorders in Chinese people who were infected with COVID-19, exploring the impact of COVID-19 on the auditory…
- Conditions
- COVID-19, Cognitive Decline, Otological Disease
- Trial name
- COVID-19 (NCT05787301)
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Pregnancy Complications, Pregnancy, High Risk
Active Pregnancy Against COVID-19
Historically and traditionally, the recommendations related to physical exercise during pregnancy have been based more on moral or cultural issues than on scientific evidence.
- Conditions
- Pregnancy Complications, Pregnancy, High Risk, Pregnancy Induced Hypertension, Newborn Morbidity
- Trial name
- ACPREGCOV (NCT04563065)
- Testing
- Exercise program, Healthy lifestyle advise
- Where
- 2 sites in Spain
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Universidad Politecnica de Madrid
Pulmonary Embolism, Covid-19
Prevalence and Characteristics of Pulmonary Embolism on COVID-19 Patients Presenting Respiratory Symptoms
Multicentric case-control study that is aims at: evaluating the prevalence of pulmonary embolism among a large population of consecutive patients admitted for COVID-19 pneumonia into two large university hospitals in Paris…
- Trial name
- COVID-EP (NCT04420312)
- Where
- France
- Volunteers
- 1,024 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Covid19
Pulmonary Rehabilitation in COVID-19 Patients
It was aimed to evaluate the respiratory functions of patients who were given respiratory rehabilitation, bed positioning and early mobilization, and the time of leaving the hospital.
- Trial name
- NCT04832867
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
COVID-19
Physical Activity and the Course of COVID-19
Being active has a beneficial effect on human immunology. Patients hospitalized for COVID-19 (coronavirus disease 2019) will be surveyed for their prior physical activity.
- Trial name
- NCT05200767
- Testing
- completing surveys
- Where
- 2 sites in Poland
- Volunteers
- 140 people
- Sponsor
- Wroclaw Medical University
Postural Orthostatic Tachycardia Syndrome
Efficacy and Safety Study of Efgartigimod in Adults With Post-COVID-19 POTS
The study aims to investigate the safety, tolerability, efficacy, pharmacodynamics (PD), pharmacokinetics (PK), and immunogenicity of efgartigimod compared to placebo in participants with post-COVID-19 postural orthostatic…
- Trial name
- POTS (NCT05633407)
- Testing
- Efgartigimod
- Where
- 11 sites in United States
- Volunteers
- 53 people
- Sponsor
- argenx
Pneumonia, Covid19
Prone Position to Improve Oxygenation in COVID-19 Patients Outside Critical Care
Prone positioning is known to improve the PaO2/FiO2 ratio and reduce mortality in patients with ARDS managed in the critical care setting.
- Trial name
- PRONE-COVID (NCT04589936)
- Testing
- Prone positioning
- Where
- United Kingdom
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Long COVID Syndrome
Does Taurine Supplementation Improve Vascular Function and Orthostatic Responses in Long COVID?
Millions have developed Long COVID (LC), and recent findings show an association between taurine deficiency (an amino acid) and symptoms in LC.
- Trial name
- NCT07312409
- Testing
- Taurine supplementation
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- York University
Covid19
Clinical Efficiency of Surgical Masks and Filtering Face-piece 2 Masks
Recent results demonstrated an increased risk of COVID-19 infection among healthcare workers (HCW), particularly when access to personal protective equipment (PPE) was inadequate. (ref).
- Trial name
- NCT04823351
- Testing
- Surgical Mask
- Where
- Switzerland
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Zurich
COVID-19, Diabetes Mellitus, Type 2
Study of the Impact of the COVID-19 Pandemic on the Management of Type 2 Diabetic Patients in a Sample in the Paris Region
The Covid-19 crisis is undoubtedly the most significant event of the early 21st century. The pandemic has profoundly changed our way of life, whether as human beings, but also as patients or caregivers.
- Trial name
- DIABETOVID (NCT05175677)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Cardiovascular Diseases
Effects of COVID-19 Pandemic on a Health Care System: Case Study of the CirculatORy System in LiThuania
Coronavirus disease of 2019 (COVID-19) affected the health care systems all around the world. The collateral damage of the pandemic on the cardiovascular (CV) care and CV mortality has been noticed and reported early.
- Trial name
- COVID-COR-LT (NCT05021575)
- Testing
- Data collection on outpatient care, Data collection on hospitalisation, Data collection on cardiovascular mortality
- Where
- 3 sites in Lithuania
- Volunteers
- 839,678 people
- Sponsor
- Vilnius University
Pregnancy Without Complications Except Getting Covid-19 Infection
Effect of Covid-19 on Outcomes of Pregnancy
To study the effect of getting Covid-19 infection during pregnancy on the outcomes of the mother and the fetus including morbidity and mortality
- Trial name
- NCT04629001
- Testing
- Covid-19 PCR , IGM
- Where
- Egypt
- Volunteers
- 1,000 people
- Sponsor
- Assiut University
Lung Fibrosis Interstitial, Post-COVID-19 Syndrome
Effect of Aerobic Exercises Versus Incentive Spirometer Device on Post-covid Pulmonary Fibrosis Patients
the aim of this study will be to investigate the effect of aerobic exercises vs incentive spirometer device on post-covid patients with residual lung diseases.
- Trial name
- NCT06191367
- Testing
- Aerobic Exercises, Incentive Spirometer Device, Traditional Chest Physiotherapy
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- McCarious Nahad Aziz Abdelshaheed Stephens
Coronavirus Disease 2019 (COVID-19) Pneumonia
Saliva PCR in Pregnant Women with COVID-19
Abstract: Objectives We aim to study the relative viral load using saliva polymerase chain reaction among pregnant women treated with Paxlovid.
- Trial name
- NCT06735300
- Testing
- Nirmatrelvir/Ritonavir (Paxlovid)
- Where
- Taiwan
- Volunteers
- 37 people
- Sponsor
- National Cheng-Kung University Hospital
COVID-19 Pneumonia
Influence of Manual Diaphragm Release on Pulmonary Functions in Women With COVID-19
Manual noninvasive respiratory techniques gained interest to treat respiratory pathologies related to COVID 19. This study designed to determine the combined effect of manual diaphragmatic release technique with the effect of…
- Trial name
- NCT05903144
- Testing
- manual therapy, breathing exercise and prone position alone
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Vaccine Preventable Disease
COVID-19 Antibody Levels After Vaccines
This study will measure the levels of nasal mucosal Immunoglobulin A (IgA) and blood serum IgA up to one year after COVID vaccination, as well as examining what factors might affect antibody levels in the nose.
- Trial name
- NCT04944134
- Testing
- COVID-19 Vaccination
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- University of North Carolina, Chapel Hill
COVID-19 Vaccine
Safety and Immunogenicity of the Inactivated Koçak-19 Inaktif Adjuvanlı COVID-19 Vaccine Compared to Placebo
The objective of this study is to determine the safety and immunogenicity of two different strengths (4 µg and 6 µg) of an inactivated COVID-19 Vaccine compared to placebo so that to demonstrate the safety and efficacy in…
- Trial name
- NCT04838080
- Testing
- Koçak-19 Inaktif Adjuvanlı COVID-19 Vaccine 4 µg/0.5 ml Vaccine, Koçak-19 Inaktif Adjuvanlı COVID-19 Vaccine 6 µg/0.5 ml Vaccine
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Kocak Farma
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