Clinical trials: COVID-19 Disease
Neurological Diseases or Conditions, Stroke, Acute
COVID-19 Prevalence and Cognitive Deficits in Neurological Patients
The purpose is to investigate the COVID-19 prevalence, associated morbidity and long-term cognitive deficits in consecutive patients presenting with acute neurological symptoms
- Conditions
- Neurological Diseases or Conditions, Stroke, Acute, Seizure Disorder
- Trial name
- Neuro-Covid (NCT04377425)
- Testing
- COVID-19 swap test PCR
- Where
- 4 sites in Denmark
- Sponsor
- Aarhus University Hospital
Critical Illness, Sedation Complication
Sedation, ANalgesia and Delirium MANagement in Intensive Care Unit
Patients with acute severe health problems often need to be admitted to specialised hospital wards called Intensive Care Units (ICUs) where they can receive emergency treatment such as mechanical ventilation to support their…
- Conditions
- Critical Illness, Sedation Complication, Intensive Care Unit Delirium, Analgesia
- Trial name
- SAnDMAN (NCT05027217)
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 3,421 people
- Sponsor
- University of Oxford
Solid Tumor Malignancy, Hematologic Malignancy
A Trial of the Safety and Immunogenicity of the COVID-19 Vaccine (mRNA-1273) in Participants With Hematologic Malignancies and Various Regimens of Immunosuppression, and in Participants With Solid Tumors on PD1/PDL1 Inhibitor Therapy
Background: Coronavirus disease (COVID-19) is a viral infection. It has spread rapidly across the globe. It has overwhelmed health systems.
- Conditions
- Solid Tumor Malignancy, Hematologic Malignancy, Leukemia, Lymphoma
- Trial name
- NCT04847050
- Testing
- Messenger ribonucleic acid (mRNA)-1273 Vaccine, Messenger ribonucleic acid (mRNA)-1273 Vaccine Booster, ECG
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- National Cancer Institute (NCI)
Feeding and Eating Disorders
Impact of COVID-19 Lockdown on Obesity and Eating Behaviors
COVID-19 lockdown presents particular challenges for people living with obesity. Indeed during this period, the lifestyle was deeply modified: diet, activity, and sleep behaviours, home office, take care of child, social…
- Trial name
- CIO (NCT04431284)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 37 people
- Sponsor
- Hospices Civils de Lyon
SARS-CoV 2
SARS-CoV2 (COVID-19) Diagnosis in Human Saliva by MALDI-TOF MS Profiling
Since March 2020, SARS-CoV2 virus (nCoV19; COVID-19) is considered pandemic. Its high rate of spread and infection in the human population and the lack of effective and validated treatment have led the authorities of several…
- Trial name
- CoviDiagMS (NCT04460638)
- Testing
- Saliva collection, Clinical assessment
- Where
- France
- Volunteers
- 779 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Covid19, Participation, Patient
The Effect of Covid-19 Process
Objective: The purpose of this study was to investigate the effect of the Covid-19 process on time management, participation, and leisure time activity. Methods: 531 individuals aged between 18-65 were included in the study.
- Trial name
- NCT04872725
- Testing
- Time management & participation & the leisure time activity
- Where
- Turkey (Türkiye)
- Volunteers
- 531 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
COVID-19
Safety and Immunogenicity of COVID-19 Vaccine, Inactivated in Healthy Population Aged From 3 to 11 Years
This is an open-labelled, bridging phase Ⅲ clinical trial of COVID-19 Vaccine manufactured by Sinovac Research \& Development Co., Ltd.
- Trial name
- NCT05137418
- Testing
- COVID-19 Vaccine,Inactivated
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Sinovac Research and Development Co., Ltd.
Covid19, Physical Disability
Physical Rehabilitation of COVID-19 Survivors by Heat Therapy
Older adults and people with underlying medical conditions are at higher risk for developing serious complications related to SARS-CoV-2 resulting in prolonged sequelae.
- Trial name
- NCT04673318
- Testing
- heat therapy, exercise training
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Amherst
Covid19
[COVID-19] Reduction of Sars-CoV-2 Oral Viral Load With Prophylactic Mouth Rinse
The purpose of this study is to test the effectiveness of prophylactic mouth rinses in reducing the amount of viruses, specifically SARS-CoV-2 in the oral cavity.
- Trial name
- NCT04719208
- Testing
- Water (E) Mouth rinse with the solution provided, Chlorhexidine gluconate (A) Mouth rinse with the solution provided, Hydrogen peroxide (B) Mouth rinse with the solution provided
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Augusta University
Ventilator Associated Pneumonia, Corona Virus Infection
Epidemiology and Outcome of Ventilator-associated Pneumonia Among Critically Ill COVID-19 Patients
The aim of this study is to determine the risk factors for development of ventilator-associated pneumonia (VAP) and to identify the prognostic factors of VAP among Coronavirus Disease 2019 (CoViD-19) patients.
- Trial name
- NCT04372576
- Testing
- Assessment of ventilator-associated pneumonia criteria
- Where
- Hungary
- Volunteers
- 30 people
- Sponsor
- Semmelweis University
COVID19
Role of Immune and Inflammatory Response in Recipients of Allogeneic Haematopoietic Stem Cell Transplantation (SCT) Affected by Severe COVID19
COVID19 pandemic currently represents a public health emergency. Based on current data, 15% of the affected individuals will develop a severe form of the disease requiring admission to hospital and respiratory support.
- Trial name
- (COVID19_BMT) (NCT04349540)
- Testing
- no intervention
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Coronavirus Disease 2019 (COVID-19)
Bone Marrow-Derived Mesenchymal Stem Cell Treatment for Severe Patients With Coronavirus Disease 2019 (COVID-19)
Coronavirus Disease 2019 (COVID-19) is spreading worldwide and has become a public health emergency of major international concern. Currently, no specific drugs or vaccines are available.
- Trial name
- NCT04346368
- Testing
- BM-MSCs
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Guangzhou Institute of Respiratory Disease
COVID-19
Descriptive and Retrospective Analysis of Acute Myocarditis Associated With Pandemic COVID-19 in Children
The study objectives are to descript clinical, biological and echocardiographic features of an acute myocarditis in children in the context of COVID-19 and to identify the underlying mechanism : direct viral damage and/or…
- Trial name
- HEART-COVID (NCT04420468)
- Where
- 4 sites in France
- Volunteers
- 20 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hospitalized Children, Covid-19 Infection
Efficacy of Human Coronavirus-immune Convalescent Plasma for the Treatment of COVID-19 Disease in Hospitalized Children
This is a multicentered, open-label, randomized controlled Phase 2 trial to evaluate the safety and efficacy of providing human coronavirus-immune convalescent plasma as treatment for COVID-19 disease in hospitalized children in…
- Trial name
- CONCOR-KIDS (NCT04377568)
- Testing
- Convalescent plasma (CP)
- Where
- 13 sites in Canada
- Sponsor
- The Hospital for Sick Children
SARS-CoV 2 Infection, Covid19
Safety and Efficacy of COVID-19 Prime-boost Vaccine in Bahrain
Coronavirus disease 2019 (COVID-19) is potentially a deadly disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that targets the lung mainly, resulting in respiratory tract infections in humans.
- Trial name
- NCT04993560
- Testing
- BBIBP-CorV, BNT162b2
- Where
- Bahrain
- Volunteers
- 305 people
- Sponsor
- Royal College of Surgeons in Ireland - Medical University of Bahrain
Covid-19 (SARS-CoV-2)
Incidence of Infection Reported by COVID-19 in Attendees of a Commercial Music Concert
From the beginning of the pandemic caused by SARS-CoV-2, most events with massive participants have been canceled due to being considered high-risk events for the SARS-CoV-2 transmission.
- Trial name
- NCT04824625
- Where
- Spain
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia
Covid19
Vitamin A Supplementation in Children With Moderate to Severe COVID-19
Severe acute respiratory syndrome (SARS)-like coronavirus 2 (Sars-CoV-2) pandemia is considered to be the current major global health issue.
- Trial name
- NCT04920760
- Testing
- Vitamin A supplement
- Volunteers
- 60 people
- Sponsor
- Shiraz University of Medical Sciences
Breast Neoplasms, Triple Negative Breast Neoplasms
Clinical and Therapeutic Outcomes by Molecular Subtype in Breast Cancer
Breast cancer is the most common cancer in women worldwide. Its molecular classification, based on hormone receptors (estrogen and progesterone), HER2 and Ki-67, defines subtypes with different prognoses and treatments.
- Conditions
- Breast Neoplasms, Triple Negative Breast Neoplasms, HER2-Positive Breast Cancer, Hormone Receptor-Positive Breast Cancer
- Trial name
- NCT07856225
- Testing
- CDK4/6 Inhibitors, Anti-HER2 Therapy, Standard Breast Cancer Treatment
- Where
- Colombia
- Volunteers
- 370 people
- Sponsor
- Fundación Santa Fe de Bogota
COVID-19
A Pilot Study of Sildenafil in COVID-19
Observe the efficacy and safety of G1(Sildenafil citrate tablets) in patients with COVID-19 under clinical actual diagnosis and treatment conditions
- Trial name
- NCT04304313
- Testing
- Sildenafil citrate tablets
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Tongji Hospital
COVID, SARS (Severe Acute Respiratory Syndrome)
Low Dose Radiotherapy in COVID-19 Pneumonia
Moderate to severe cases of SARS-associated ARDS based on inclusion/ exclusion criteria and the decision made in multi- disciplinary team are treated with 0.5 Gy whole lung radiation.
- Trial name
- NCT04390412
- Testing
- Low Dose Radiotherapy
- Where
- Iran
- Volunteers
- 5 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
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