Clinical trials: COVID-19 Drug Treatment
Long COVID
The Efficacy and Safety of a Chinese Herbal Medicine for Long COVID Associated Fatigue
This is a randomized, double-blinded, placebo-controlled clinical trial to determine the efficacy and safety of a Chinese herbal medicine (Shenlingcao oral liquid) for treating long COVID associated fatigue.
- Trial name
- NCT05684952
- Testing
- Shenlingcao Oral Liquid
- Where
- China
- Volunteers
- 152 people
- Sponsor
- Hong Kong Baptist University
COVID
The Efficacy of Ivermectin in Larger Doses in COVID-19 Treatment
Efficacy of Ivermectin in larger doses in COVID-19 treatment
- Trial name
- NCT04351347
- Testing
- Ivermectin
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Tanta University
COVID-19
Utility of Lactoferrin as an Adjunct Therapeutic Agent for COVID-19
There is currently no clinically proven specific antiviral agent available for SARS-CoV-2 infection. Supportive treatment, including oxygen therapy, remains the most important management strategy.
- Trial name
- NCT04421534
- Testing
- Lactoferrin
- Volunteers
- 150 people
- Sponsor
- Cairo University
COVID-19, SARS-CoV-2
Azithromycin for COVID-19 Treatment in Outpatients Nationwide
This individually randomized telemedicine-based trial aims to evaluate the efficacy of a single dose of azithromycin for prevention of progression of COVID-19 in patients with a recent positive SARS-CoV-2 test who are not…
- Trial name
- ACTION (NCT04332107)
- Testing
- Azithromycin
- Where
- United States
- Volunteers
- 263 people
- Sponsor
- Thomas M. Lietman
Elderly Women
Telerehabilitation on Physical and Mental Health of the Elderly in the Covid-19 Pandemic Context
Introduction: Due to the COVID-19 pandemic scenario, social distancing has become the main strategy to contain this pandemic, causing negative impacts on the physical and mental health of the elderly population.
- Trial name
- NCT05465811
- Testing
- Program of physical exercises and health education by telerehabilitation
- Where
- Brazil
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Paulista University
COVID, Coronavirus Infection
P2Et Extract in the Symptomatic Treatment of Subjects With COVID-19
Antioxidants, and particularly polyphenols, have shown protection in respiratory pathologies, which is related to the decrease in the severity of the clinical picture and suppression of inflammation.
- Conditions
- COVID, Coronavirus Infection, SARS-CoV 2, COVID19
- Trial name
- NCT04410510
- Testing
- P2Et (Caesalpinia spinosa extract)
- Where
- Colombia
- Volunteers
- 100 people
- Sponsor
- Hospital Universitario San Ignacio
COVID-19
Efficacy and Safety of Direct Anti HCV Drugs in the Treatment of SARS-COV-2 (COVID-19)
COVID 19 which started from a zoonotic transmission related to crowded markets was confirmed to have a high potential for transmission to close contacts on 20 January 2020 by the National Health Commission of China and it was…
- Trial name
- CCOVID-19 (NCT04535869)
- Testing
- Sofosbuvir 400 MG plus Daclatasvir 200mg
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mansoura University
COVID-19, Viral Pneumonia Human Coronavirus
Silymarin in COVID-19 Pneumonia
A randomized placebo controlled trial to assess the clinical outcome in COVID-19 Pneumonia following administration of Silymarin owing to its role as a p38 MAPK pathway inhibitor and its antiviral, anti-inflammatory and…
- Trial name
- SCOPE (NCT04394208)
- Testing
- Silymarin
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Healthy Participants
Drug-Drug Interaction Study to Estimate the Effect of PF-07321332/Ritonavir and Ritonavir on Midazolam in Healthy Participants
The purpose of this study is to estimate the effect PF-07321332/Ritonavir and Ritonavir on Midazolam (a cytochrome P450 [CYP]3A4 substrate) in Healthy Adult Participants.
- Trial name
- NCT05032950
- Testing
- Midazolam, PF-07321332/ritonavir + Midazolam, Ritonavir + Midazolam
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer
Acute Respiratory Tract Infection, Acute Respiratory Insufficiency
An Open Randomized Study of Dalargin Efectiveness in Combination With Leitragin Drug in Patients With Severe and Critical Manifestations of SARS-COVID-19
The purpose of the study is to evaluate an effectiveness of the drug Dalargin in combination with Leitragin for the prevention and treatment of severe pulmonary complications symptoms associated with severe and critical…
- Conditions
- Acute Respiratory Tract Infection, Acute Respiratory Insufficiency, Pneumonia, Septic Shock
- Trial name
- NCT04346693
- Testing
- Standard therapy recommended by the Ministry of Health of the Russian Federation., Standard therapy recommended by the Ministry of Health of the Russian Federation and Leitragin intramuscular injection, Standard therapy recommended by the Ministry of Health of the Russian Federation and Leitragin inhalation
- Where
- Russia
- Volunteers
- 320 people
- Sponsor
- Burnasyan Federal Medical Biophysical Center
Coronavirus, Coronavirus Infection
Natural Killer Cell (CYNK-001) Infusions in Adults With COVID-19
This study is a Phase 1 / 2 trial to determine the safety and efficacy of CYNK-001, an immunotherapy containing Natural Killer (NK) cells derived from human placental CD34+ cells and culture-expanded, in patients with moderate…
- Conditions
- Coronavirus, Coronavirus Infection, Severe Acute Respiratory Syndrome Coronavirus 2, Pneumonia
- Trial name
- CYNKCOVID (NCT04365101)
- Testing
- CYNK-001
- Where
- 4 sites in United States
- Volunteers
- 7 people
- Sponsor
- Celularity Incorporated
Treatment of Covid-19 Virus Infection
Effect of a Combination of Treatment of Reginmune Capsule and Immunofree Tablets in the Treatment of Mild to Moderate COVID-19 Patients
While novel drug discovery and vaccine studies are time taking process, re-purposing old drugs against the COVID-2019 epidemic can help identify treatments, with known pre-clinical, pharmacokinetic, pharmacodynamic, and toxicity…
- Trial name
- NCT04494204
- Testing
- Immunofree tablets and Reginmune capsule
- Where
- 3 sites in India
- Volunteers
- 100 people
- Sponsor
- PUNEET MITTAL
Complementary Therapies
Complementary And Alternative Medicine During The COVID-19 Pandemic
Complementary and alternative medicine is frequently used in the treatment of several groups of diseases.
- Trial name
- NCT04884321
- Testing
- Complementary And Alternative Medicine
- Where
- Turkey (Türkiye)
- Volunteers
- 3,242 people
- Sponsor
- Hasan Kalyoncu University
COVID19
Nitric Oxide Inhalation Therapy for COVID-19 Infections in the ED
The spread of novel Coronavirus (2019-nCoV) related infection (COVID-19) has led to many patient presentations in the emergency department for respiratory complaints, with many of these patients requiring ICU admission and…
- Trial name
- NO COV-ED (NCT04338828)
- Testing
- Nitric Oxide Gas, Inhaled Supplemental Oxygen
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Massachusetts General Hospital
Coronavirus Disease 2019
Evolution of Coronavirus Disease 2019 (COVID-19) Patients in Extremadura
At the end of January 2020, the international community was informed of the presence of a new viral disease that started in Wuhan (China) and spread rapidly throughout the world.
- Trial name
- COVIXTREM (NCT04724850)
- Where
- Spain
- Volunteers
- 440 people
- Sponsor
- Juan Fernando Masa Jiménez
Post COVID Condition
RECLAIM Adaptive Platform Trial for PCC Treatments
RECLAIM is a Phase III, multi-domain, randomized, controlled, adaptive platform trial, designed to evaluate efficacy and safety of repurposed medications in patients with post-COVID condition (PCC).
- Trial name
- RECLAIM (NCT07280572)
- Testing
- Metformin, colchicine
- Where
- Netherlands
- Volunteers
- 1,250 people
- Sponsor
- Janneke van de Wijgert
COVID
Efficacy of Faviprevir in COVID-19 Treatment
Faviprevir in COVID-19 treatment
- Trial name
- NCT04351295
- Testing
- Favipiravir, Chloroquine
- Where
- Egypt
- Volunteers
- 92 people
- Sponsor
- Tanta University
COVID-19
Inflammatory Regulation Effect of NAC on COVID-19 Treatment
Study times to evaluate the efficacy of N-Acetylcysteine therapy in the management of adult admitted patients with COVID-19.
- Trial name
- INFECT-19 (NCT04455243)
- Testing
- N-Acetyl cysteine
- Volunteers
- 1,180 people
- Sponsor
- Dr. Tariq Alhawassi
Type 2 Diabetes
Social Media-Delivered Patient Education in Enhancing Type 2 Diabetics Self-Management and Attitudes During the COVID-19 Pandemic
The current study was to develop a software "Line@" based health education program, providing video-based health information and communication between diabetes patients and health-care professionals.
- Trial name
- NCT04876274
- Testing
- TMU-LOVE
- Where
- Taiwan
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
COVID-19
Dornase Alpha for the Treatment of COVID-19
In this study, the effectiveness of the Dornase Alpha treatment, which is known to reduce the viscosity of respiratory secretions, will be investigated in new diagnosed and severe COVID-19 patients separately.
- Trial name
- NCT04432987
- Testing
- Pulmozyme
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Acibadem University