Clinical trials: COVID-19 Pandemic
Anosmia, Covid19
Visual-OLfactory Training in Participants With COVID-19 Resultant Loss of Smell
Olfactory dysfunction is a defining symptom of COVID-19 infection. As the number of total, confirmed COVID-19 cases approached 19 million in the United States, it is estimated that there will be 250,000 to 500,000 new cases of…
- Conditions
- Anosmia, Covid19, Ageusia, Hyposmia
- Trial name
- VOLT (NCT04710394)
- Testing
- Smell Training
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Washington University School of Medicine
Paediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-Cov-2
Paediatric Inflammatory Multisystem Syndrome During COVID-19 Pandemic
During the COVID-19 pandemic, a small minority of children have been presenting to acute paediatric services with a new syndrome, Paediatric Inflammatory Multisystem Syndrome temporally associated with SARS-Cov-2 (PIMS-TS).
- Trial name
- NCT04761913
- Where
- 6 sites in United Kingdom
- Volunteers
- 40 people
- Sponsor
- Anglia Ruskin University
Depression, Generalized Anxiety
The Impact of Information Sources on Mental Health During the COVID-19 Pandemic
Study description: The present study seeks to investigate the impact of various sources of information on psychopathology, and specifically health anxiety, depression, and general anxiety, during the COVID-19 pandemic.
- Conditions
- Depression, Generalized Anxiety, Health Anxiety
- Trial name
- NCT04442360
- Testing
- Prospective study with two measurement points investigating the impact of viral mitigation protocols on mental health
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Anxiety, COVID-19 Pandemic
SMILE: Clinical Trial to Evaluate Mindfulness as Intervention for Racial and Ethnic Populations During COVID-19
The goal of this clinical trial is to evaluate the SMILE app, a Digital Health Platform (DHP), that will deliver a mindfulness intervention, designed to mitigate COVID-19 related stress.
- Trial name
- SMILE (NCT06242080)
- Testing
- Mindfulness
- Where
- United States
- Volunteers
- 398 people
- Sponsor
- University of North Carolina, Chapel Hill
Postoperative Complications, Appendicitis
Impact of SARS-Cov2 Pandemic on Severity of Perioperative Complications in Patients Undergoing Appendectomy
There are 2 types of surgical procedures to remove the appendix : open appendectomy or laparoscopic appendectomy. About 60000 appendectomies are performed every year in France.
- Conditions
- Postoperative Complications, Appendicitis, COVID-19 Pandemic, Appendicitis With Peritonitis
- Trial name
- SAP-19 (NCT05178251)
- Testing
- appendectomy
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Central Hospital, Nancy, France
Aging
Acceptability, Representations and Experiences of the COVID-19 Pandemic
The "ARECOVID" project is a comprehensive sociological study of what is being played out in organizational terms in the face of the COVID-19 pandemic.
- Trial name
- ARECOVID (NCT04993573)
- Testing
- Questionnaire, Individual interview
- Where
- France
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Stroke
Global Impact of the COVID 19 Pandemic on Stroke Care, Cerebral Venous Thrombosis, and Subarachnoid Hemorrhage
A 1-year analysis of global selected stroke metric data will be conducted comparing the results during the Covid-19 pandemic to the pre-pandemic period.
- Trial name
- NCT04934020
- Testing
- Pre-pandemic stroke related metrics, Stroke related metrics during the pandemic
- Where
- 2 sites in United States
- Volunteers
- 345,089 people
- Sponsor
- Boston Medical Center
COVID-19 Pandemic, Endocrine System Diseases
Hormonal Contributors to COVID-19 Infection (COV-ENDO)
The goal of this observational study is to measure the changes in the parameters of endocrine function and tissue sensitivity to hormones induced by SARs-CoV-2 infection.
- Trial name
- COV-ENDO (NCT05749770)
- Testing
- blood testing
- Where
- Italy
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Istituto Auxologico Italiano
Chronic Stress
Virtual Mindfulness Rounds in the Time of COVID-19 Pandemic
Mindfulness education will be provided via a virtual platform to see if staff stress can be decreased during this time of pandemic.
- Trial name
- NCT04431297
- Testing
- Mindfulness Rounds
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
COVID-19 Pandemic, Professional Stress
Mental Health of Professionals of the Silver Economy of New Aquitaine : Online Survey of Accommodation Establishments for Old People and Home Assistance Establishments
The purpose of this study is identify the psychological impact of the coronavirus-19 pandemic on professionals in residential care facilities for old people and home help professionals in New-Aquitaine by : 1.
- Trial name
- SILVER NA (NCT05381883)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Charles Perrens, Bordeaux
COVID-19 Pneumonia
Covid-19 Pandemic and Use of Video Laryngoscopy
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes a highly contagious infection with the highest viral load in the upper respiratory secretions.
- Trial name
- NCT05121701
- Testing
- Videolaryngoscope, Macintosh Laryngoscope
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Van Bölge Eğitim ve Araştırma Hastanesi
Transcranial Direct Current Stimulation, Mental Health Issue
Promote Brain Resilience for the Coronavirus (COVID-19) Pandemic
Background: By the end of 2020, the coronavirus disease (COVID-19) pandemic resulted in over 84 million cases and nearly 2 million deaths.
- Conditions
- Transcranial Direct Current Stimulation, Mental Health Issue, Public Health, Resilience, Psychological
- Trial name
- MBNPR (NCT05293431)
- Testing
- Transcranial Alternate Current Stimulation
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Institut Guttmann
COVID, Pregnancy Complications, Infectious
International Lung UltraSound Analysis (ILUSA) Study
Currently there is a great need for an accurately and rapid assessment of patients suspected for Covid-19. Like CT, Lung Ultrasound (LUS) examination can potentially help with the initial triage of patients but also help track…
- Conditions
- COVID, Pregnancy Complications, Infectious, Pregnancy Related, Pregnancy, High Risk
- Trial name
- ILUSA (NCT04353141)
- Testing
- standardized Lung Ultrasound (LUS) examination
- Where
- 7 sites in Belgium, Italy and 1 more
- Volunteers
- 1,850 people
- Sponsor
- KU Leuven
COVID-19 Pandemic
Recombinant SARS-CoV-2 Fusion Protein Vaccine (V-01) Phase III
A Global, Multi-center, Randomized, Double-Blind, Placebo-Controlled, Phase III Clinical Study to Evaluate the Efficacy, Safety, and Immunogenicity of Recombinant SARS-CoV-2 Fusion Protein Vaccine (V-01) in Adults Aged 18 Years…
- Trial name
- COVID-19 (NCT05096845)
- Testing
- Recombinant SARS-CoV-2 fusion protein vaccine (V-01), Blank Preparation of Recombinant SARS-CoV-2 Fusion Protein Vaccine (V-01)
- Where
- 25 sites in Indonesia, Philippines and 1 more
- Volunteers
- 22,500 people, healthy volunteers welcome
- Sponsor
- Livzon Pharmaceutical Group Inc.
Body Weight, Nutrition, Healthy
Nutritional Status of Adult Slovenes After the Covid-19 Epidemic
There is objective need to examine nutritional status (i.e., body mass index (BMI), body composition and dietary intake) of healthy adult Slovenes after SARS-CoV-2 (Covid-19) epidemic period.
- Conditions
- Body Weight, Nutrition, Healthy, COVID-19 Pandemic
- Trial name
- SloFitCovid (NCT05438966)
- Testing
- No intervention
- Where
- Slovenia
- Volunteers
- 833 people, healthy volunteers welcome
- Sponsor
- Barbara Jakše s.p.
Opioid Use Disorder
Remote Methadone Ingestion Surveillance Trial (RMIST)
The Remote Methadone Ingestion Surveillance Trial (RMIST) will explore a potential method of methadone ingestion surveillance that may mitigate patient safety risks of take-home methadone treatment regimens while minimizing the…
- Trial name
- NCT05259501
- Testing
- RMIST
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Texas Southwestern Medical Center
Covid19, Personnel, Hospital
Psychologic Impact of COVID-19 Pandemic on the Hospital Staff of the Nouvelle Aquitaine Area
Evaluation of the psychological impact of the COVID-19 pandemic on hospital staff in the French Nouvelle Aquitaine area, through a longitudinal study with repeated self-administered psychologic scales
- Conditions
- Covid19, Personnel, Hospital, Work-Related Condition, Work-Related Stress Disorder
- Trial name
- IMPSY-COV (NCT04945837)
- Testing
- self administered questionnaire
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Charles Perrens, Bordeaux
Older Adults
Remote Interactive Intervention for Loneliness
Background: During the COVID-19 pandemic, governments around the world adopted the practice of physical distancing, which increased the loneliness experienced by seniors and indirectly affected their quality of life and social…
- Trial name
- NCT05459103
- Testing
- Bidirectional remote interaction intervention, Unidirectional remote interaction intervention
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Yang Shang-Yu
Covid-19
Treatment of Severe and Critical COVID-19 Pneumonia With Convalescent Plasma
Open label two arms, non randomized Convalescent Plasma treatment to severe and critical pneumonia COVID-19 hospitlaized patients compared to a historical cohort with matched controls.
- Trial name
- NCT04432103
- Testing
- Anti SARS-CoV 2 Convalescent Plasma in severe COVID-19 patients, Anti SARS-CoV 2 Convalescent Plasma in critical COVID-19 patients
- Where
- Mexico
- Volunteers
- 6 people
- Sponsor
- Centro Medico ABC
Liver Diseases
Effect of Lockdown During COVID 19 Pandemic on Liver Disease and Metabolic Parameters.
The novel corona virus disease (COVID-19), pandemic has costed lives of several hundred thousands and affected millions. Comorbidities such as metabolic syndrome components and chronic liver disease have been associated with more…
- Trial name
- NCT05028842
- Testing
- No intervention
- Where
- India
- Volunteers
- 230 people
- Sponsor
- Institute of Liver and Biliary Sciences, India