Clinical trials: COVID-19 Pneumonia
Covid19, Rheumatic Fever
Impact of COVID-19 Pandemic and Social Distancing on Mental Health of Chronic Inflammatory Rheumatism Affected Patients
Recent studies have highlighted the consequences of COVID-19 pandemic and social distancing on mental health of individuals. The aim of this study is to evaluate those consequences within a sample of inflammatory chronic…
- Conditions
- Covid19, Rheumatic Fever, Mental Disorder
- Trial name
- EMOPTION (NCT04798053)
- Testing
- Questionnaire, blood sample and salivary sample
- Where
- 7 sites in France
- Volunteers
- 259 people
- Sponsor
- University Hospital, Bordeaux
Diarrhea, COVID-19
Studies of COVID-19 Patients Treated With Oral Bismuth Subsalicylate (Pepto-Bismol)
The Center for Disease Control (CDC) and World Health Organization (WHO) have deemed the COVID-19 virus a global pandemic of unprecedented severity in modern times.
- Trial name
- SABER-C (NCT04811339)
- Testing
- Bismuth Subsalicylate 262 milligram (mg) Oral Tablet, Chewable
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Cincinnati
COVID-19
Sirolimus Treatment in Hospitalized Patients With COVID-19 Pneumonia
The main objective of our study is to determine if treatment with sirolimus can improve clinical outcomes in hospitalized patients with COVID-19.
- Trial name
- SCOPE (NCT04341675)
- Testing
- Sirolimus
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- University of Cincinnati
Covid19
Low Dose Lung Radiotherapy to Treat COVID-19 Pneumonia
The purpose of this study is to document the feasibility and tolerability of low dose thoracic radiotherapy in patients with WHO level 5 COVID 19 infections.
- Trial name
- NCT04572412
- Testing
- Low dose Radiotherapy
- Where
- United Kingdom
- Volunteers
- 2 people
- Sponsor
- Lancashire Teaching Hospitals NHS Foundation Trust
Vitamin d Deficiency, COVID-19
Risk in Devel Long-COVID in Contracting SARS-CoV-2 Infection After COVID-19 Vaccination in Relation to Vitamin D3 Suppl
The aim of this observational retrospective study is to evaluate the effect of supplementation with cholecalciferol D3 in reducing the risk of: occurence of Long COVID syndrome after acute COVID-19 illness occurence of SARS-CoV-2…
- Conditions
- Vitamin d Deficiency, COVID-19, Long COVID
- Trial name
- LONGVITAVAX2 (NCT06452082)
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- IRCCS San Raffaele
Covid-19
Hydrogen Therapy in Patients With Moderate Covid-19
SARS-CoV-2 is the agent responsible for a new infectious respiratory disease called Covid-19 (for CoronaVirus Disease 2019) which is mainly characterized by potentially severe and fatal lung damage.
- Trial name
- H2Covid (NCT04633980)
- Testing
- Mixture 3,6% H2 in N2 (96.4%)
- Where
- France
- Volunteers
- 12 people
- Sponsor
- University Hospital, Grenoble
COVID-19, Influenza A
Prospective Clinical Evaluation of COVID/Flu Detect™ Rapid Self-Test in Symptomatic Subjects for Non-Prescription Over-the-Counter (OTC) Use
The goal of this study is to evaluate the performance of the COVID/Flu Detect™ Rapid Self-Test when used in a home-like setting by lay users.
- Conditions
- COVID-19, Influenza A, Influenza B
- Trial name
- NCT06734741
- Testing
- COVID/Flu Detect™ Rapid Self-Test
- Where
- 10 sites in United States
- Volunteers
- 899 people
- Sponsor
- InBios International, Inc.
Critical Confirmed Coronavirus Disease (COVID)-19
A Study to Evaluate the Efficacy and Safety of Sirukumab in Confirmed Severe or Critical Confirmed Coronavirus Disease (COVID)-19
The purpose of this study is to evaluate the clinical response of sirukumab (administered as a single intravenous dose) plus standard of care (SOC) compared to placebo plus SOC in COVID-19.
- Trial name
- NCT04380961
- Testing
- Sirukumab, Standard of Care (SOC)
- Where
- 16 sites in United States
- Volunteers
- 212 people
- Sponsor
- Janssen Pharmaceutica N.V., Belgium
SARS-CoV Infection, Covid19
KIDney Injury in Times of COVID-19 (KIDCOV)
There is an unmet need to evaluate the impact of sub-clinical/mild COVID19 disease in the outpatient setting on prevalent and incident renal injury, as this data is currently unavailable.
- Conditions
- SARS-CoV Infection, Covid19, Corona Virus Infection, Acute Kidney Injury
- Trial name
- KIDCOV (NCT04705766)
- Testing
- Urine Collection
- Where
- 3 sites in United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
COVID-19, Upper Respiratory Infection
A Noninvasive Multimodal Biosensing Device for Screening and Monitoring Response to Treatment of Infectious Respiratory Diseases
Background: The COVID-19 outbreak has strained the health care system. New tools are needed for diagnostic testing and monitoring of people who have the virus.
- Conditions
- COVID-19, Upper Respiratory Infection, Lower Respiratory Infection
- Trial name
- NCT05035420
- Testing
- Fitbit, Douglas Bag, Periflux 6000 EPOS
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Covid19, Hematologic Malignancy
Efficacy and Safety of the Anti- COVID-19 Vaccin in Clinical Hematology Patients
Coronavirus disease 2019 (COVID-19) is an emerging infectious disease that was first reported in December 2019 in Wuhan, China. Infection with this new coronavirus called SARS-CoV-2 can lead to fatal pneumonia associated with…
- Conditions
- Covid19, Hematologic Malignancy, Vaccine Response Impaired
- Trial name
- HEMVACO (NCT04852796)
- Testing
- Patients with hemopathy
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Centre Hospitalier de Cornouaille
Mechanical Ventilation, Covid19
Mortality in Patients With Severe COVID-19 Pneumonia Who Underwent Tracheostomy
Background: Invasive mechanical ventilation (IMV) in COVID-19 patients has been associated with a high mortality rate. In this context, the utility of tracheostomy has been questioned in this group of ill patients.
- Conditions
- Mechanical Ventilation, Covid19, Tracheostomy
- Trial name
- NCT04642703
- Where
- Chile
- Volunteers
- 100 people
- Sponsor
- University of Chile
Healthy Volunteers
A Trial to Learn if Different Doses of REGN17092 Are Safe in Healthy Adults
The purpose of this study is to learn about the safety and tolerability of different doses of REGN17092 administered with a needle either under the skin (called "subcutaneous") or into a vein (called an "infusion") in healthy…
- Trial name
- NCT05923424
- Testing
- REGN17092
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Regeneron Pharmaceuticals
Critical Illness, Covid19
Psychological Impact of COVID-19 Outbreak on Caregivers
Based on the experience of previous pandemics, countries reacted by applying different upgrade strategies to prevent or delay the widespread of the disease.
- Conditions
- Critical Illness, Covid19, Stress Disorders, Post-Traumatic
- Trial name
- PSY-CO-ICU (NCT04511780)
- Testing
- questionnaire filling
- Where
- 51 sites in France
- Volunteers
- 701 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Covid19, Ventilators, Mechanical
Efficacy of FES Cycling After a Severe Form of COVID-19
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing the coronavirus disease 2019 (COVID-19) affect at late march 2021 more than 127 millions of persons worldwide (including more than 4.5 millions in France…
- Conditions
- Covid19, Ventilators, Mechanical, Respiratory Distress Syndrome
- Trial name
- FESrehabCoV (NCT04841746)
- Testing
- Physical therapy that include a standardized cycling training with functional electrical stimulation, Physical therapy that include a standardized cycling training with no additional functional electrical stimulation
- Where
- France
- Volunteers
- 22 people
- Sponsor
- Hospices Civils de Lyon
SARS-CoV-2 Infection
Halodine Nasal Antiseptic in Patients With COVID-19
Povidone iodine (PVP-I) is a well-known broad spectrum, resistance free antimicrobial agent that has a long history of safe and effective use.
- Trial name
- NCT04517188
- Testing
- Povidone-Iodine Solution 1.25% w/w [0.125% available iodine] USP
- Volunteers
- 40 people
- Sponsor
- Halodine LLC
COVID-19, SARS-CoV Infection
Glycine Supplement for Severe COVID-19
This study will explore whether a daily supplement of glycine, a substance that has antiinflammatory, cytoprotective, and endothelium-protecting effects, can improve mortality, as well as clinical and biochemical parameters, in…
- Conditions
- COVID-19, SARS-CoV Infection, SARS (Severe Acute Respiratory Syndrome), SARS Pneumonia
- Trial name
- NCT04443673
- Testing
- Glycine
- Where
- Mexico
- Volunteers
- 59 people
- Sponsor
- Instituto Nacional de Enfermedades Respiratorias
Post-Acute COVID-19 Syndrome, Post-Acute COVID-19
Safety and Efficacy of Anakinra Treatment for Patients With Post Acute Covid Syndrome
The PRECISION is a proof-of-concept, phase II randomized clinical trial aiming to evaluate the efficacy and safety of anakinra in patients with Post-Acute COVID Syndrome (PACS) of the pro-inflammatory respiratory phenotype.
- Conditions
- Post-Acute COVID-19 Syndrome, Post-Acute COVID-19, Long COVID
- Trial name
- PRECISION (NCT05926505)
- Testing
- Anakinra 149 MG/ML Prefilled Syringe [Kineret]
- Where
- 24 sites in Germany, Greece and 2 more
- Volunteers
- 182 people
- Sponsor
- Hellenic Institute for the Study of Sepsis
COVID-19
Detection of COVID-19 Using Breath Analysis - Validation Study.
Detection of the 2019 novel Coronavirus (SARS-CoV-2) using breath analysis - Validation study.
- Trial name
- NCT05224622
- Testing
- VOX
- Where
- Israel
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Scentech Medical Technologies Ltd
COVID-19, Palliative Care
Palliative Care in Patients With COVID-19: Analysis of Costs of Hospitalization in Wards and Intensive Care Units
The confrontation of COVID-19 foreshadowed a serious crisis of scarce health resources worldwide. To assist in this confrontation, the Palliative Care Scientific Technical Core of the Clinical Hospital, School of Medicine, Sao…
- Trial name
- NCT05897229
- Testing
- Analysis of costs with patient care during hospitalization
- Volunteers
- 200 people
- Sponsor
- University of Sao Paulo General Hospital
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