Clinical trials: COVID-19 Pneumonia
Coronavirus Disease 2019
Detection Rate of SARS-CoV-2 in Male Genitourinary System and Its Impact on Male Reproductive Health.
This study will evaluate the changes in sexual function, reproductive function and mental health of male patients discharged from the hospital with COVID-19, and the impact of SARS-CoV-2 on male reproductive health and mental…
- Trial name
- COVID-19 (NCT04388631)
- Testing
- Coronavirus Disease 2019
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
SARS-CoV 2, COVID
In-vitro Diagnostic Test to Predict COVID-19 Mortality and Disease Severity
The COVID-19 Androgen Sensitivity Test is a non-invasive In-Vitro Diagnostic device that utilizes Next Generation Sequencing Technology (NGS).
- Conditions
- SARS-CoV 2, COVID, COVID-19, Androgenetic Alopecia
- Trial name
- NCT04368897
- Testing
- CAG length <22, CAG length >=22
- Where
- Spain
- Sponsor
- Applied Biology, Inc.
COVID-19, Pulmonary Fibrosis
Home Monitoring and Evaluation After Admission for COVID-19 in the Netherlands
To date, little is known about the short and long-term complications of COVID-19. In order to obtain more insights in disease course and recovery of COVID-19 and to improve care after hospital admission, patients with COVID-19…
- Trial name
- HOMECOMIN' (NCT04488562)
- Where
- 3 sites in Netherlands
- Volunteers
- 133 people
- Sponsor
- Erasmus Medical Center
SARS-CoV Infection, Covid19
A Triple Combination Antiviral Coronavirus Therapy (TriACT) for COVID-19
New outpatient treatments for COVID-19 are urgently needed. There is some evidence that a combination of three medications currently used to treat other viral infections could be effective in fighting this new virus.
- Trial name
- TriACT (NCT04605588)
- Testing
- Nitazoxanide, Ribavirin, Hydroxychloroquine
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Rutgers, The State University of New Jersey
COVID-19
Ivermectin for Post Exposure Prophylaxis of Covid-19
Post exposure prophylaxis of healthy contacts is among the measures used for outbreak control of several infectious diseases (e.g., pandemic influenza).
- Trial name
- I-CPEP (NCT05231603)
- Testing
- Ivermectin
- Where
- 10 sites in Malaysia
- Volunteers
- 50 people
- Sponsor
- Clinical Research Centre, Malaysia
Covid19, Stress
A Study on Prevalence, Protection and Recovery From COVID-19 in Seasoned Yoga Practitioners in Comparison to Age and Gender Matched Controls
The study is a randomized controlled trail with an observational arm and aims at collecting information on the prevalence of COVID 19 infection in seasoned yoga practitioners by comparing it with the prevalence of COVID-19…
- Conditions
- Covid19, Stress, Anxiety Depression
- Trial name
- NCT04498442
- Testing
- Simha Kriya, Reading a Book
- Where
- United States
- Volunteers
- 8,519 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Covid19, Respiratory Failure
Proning Early in Awake COVID-19 Hypoxic Respiratory Failure (PREACHR) Study
The aim of this proposal is to study whether proning, a technique that has previously been shown to improve lung function in patients with acute respiratory distress syndrome (ARDS), can prevent those with mild to moderate…
- Trial name
- PREACHR (NCT05130541)
- Testing
- Proning, Supportive Care
- Where
- United States
- Volunteers
- 219 people
- Sponsor
- New York Hospital Queens
COVID-19
Safe and Timely Cessation of Isolation of Patients With COVID-19 (The SCIP-COVID-19) Study
Rationale: In the treatment, care and isolation of COVID-19 patients, one of the most important issues is determining the duration of infectiousness.
- Trial name
- SCIP-COVID19 (NCT05346042)
- Testing
- duration infectiousness
- Where
- Netherlands
- Volunteers
- 7,000 people
- Sponsor
- Anne Voor in 't holt
Acute Kidney Injury, COVID-19
Prediction of Acute Kidney Injury in Patients With COVID-19
The two biomarkers determined in urine, "Tissue Inhibitor of Metalloproteinases 2 (TIMP-2)" and "Insulin-like Growth Factor-Binding Protein 7 (IGFBP7)", can indicate the occurrence of Acute kidney injury (AKI) in cardiac surgery…
- Conditions
- Acute Kidney Injury, COVID-19, ARDS
- Trial name
- NCT04406688
- Where
- 13 sites in Germany, Italy and 3 more
- Volunteers
- 300 people
- Sponsor
- University Hospital Muenster
Ards, Covid19
FX06 to Rescue Acute Respiratory Distress Syndrome During Covid-19 Pneumonia
Vascular leakage following endothelial injury, responsible for interstitial and alveolar edema, is a major feature of pathogen induced acute lung injury.
- Conditions
- Ards, Covid19, Pneumonia
- Trial name
- FX-COVID (NCT04618042)
- Testing
- FX06
- Where
- 3 sites in France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
COVID-19, Critical Care
The COVID-ICU Healthcare Professional Study
The project is a longitudinal cohort study based on an electronic questionnaire on views and experiences of COVID-ICU Health care professionals during the pandemic.
- Conditions
- COVID-19, Critical Care, Intensive Care Units, Health Personnel
- Trial name
- NCT04372056
- Testing
- Views and experiences of health care professionals working in intensive care units during the COVID-19 pandemic
- Where
- Norway
- Volunteers
- 484 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
COVID-19
Hydroxychloroquine in COVID-19 Patients
Many reports argued about the possible beneficial effects of Hydroxychloroquine in treating COVID-19 patients and this study was designed to investigate this claim
- Trial name
- NCT04394442
- Testing
- Hydroxychloroquine
- Where
- Saudi Arabia
- Volunteers
- 200 people
- Sponsor
- Samah Lutfy
Covid19
Efficacy of Reinforcing Standard Therapy in COVID-19 Patients With Repeated Transfusion of Convalescent Plasma
The coronavirus disease 2019 (COVID-19) was classified as a pandemic by the World Health Organization (WHO) in March 2020. The SARS-COV-2 virus is easily transmissible and there is currently no approved treatment with effective…
- Trial name
- NCT04803370
- Testing
- Convalescent Plasma with antibody against SARS-CoV-2., Standard treatment for COVID-19
- Where
- Spain
- Volunteers
- 55 people
- Sponsor
- Hospital Son Llatzer
COVID-19 Pneumonia
Efficacy and Safety of Tocilizumab in the Treatment of SARS-Cov-2 Related Pneumonia
The current spread of the COrona VIrus Disease-2019 (COVID-19) epidemic in Italy, and the current lack of effective and approved drugs for its treatment, poses the problem of Severe acute respiratory syndrome coronavirus-2…
- Trial name
- TOSCA (NCT04332913)
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of L'Aquila
COVID-19
Clinical Evaluation of Rapid Antibody Test for Covid-19
Rapid, accurate diagnosis of Covid-19 would greatly help to improve clinical management of patients presenting with symptoms of possible Covid-19. Currently results of the standard test for the virus take 2-3 days to be reported.
- Trial name
- CERAbTc-19 (NCT05298462)
- Testing
- Livzon Rapid Antibody Test for COVID-19
- Where
- United Kingdom
- Volunteers
- 397 people
- Sponsor
- University of Southampton
COVID-19, SARS-CoV-2
Safety and Immunogenicity Study of a Booster Dose of the Investigational CV0501 mRNA COVID-19 Vaccine in Adults at Least 18 Years Old
Prevention of COVID-19 caused by SARS-CoV-2.
- Trial name
- NCT05477186
- Testing
- CV0501 (3 μg), CV0501 (6 μg), CV0501 (12 μg)
- Where
- 17 sites in United States, Australia and 1 more
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Covid19
Mucosal Immunity in Terms of SARS-CoV-2 Antibodies in Saliva After COVID-19 Infection and Vaccination
The Primary Objective of This Single-center Study is to Investigate the SARS-CoV-2 Spike Glycoprotein RBD Antibody Concentration in Saliva and Serum in Healthy Non Vaccinated and Non-SARS-CoV-2 Infected, COVID-19 Convalescents…
- Trial name
- NCT04842305
- Testing
- Blood- and saliva tests
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Lenanrt Friis-Hansen
COVID-19
Antihistamines, Amantadine and Evolution of COVID-19
The rates of symptomatic COVID19 infection, hospital admission among COVID19 cases and survival would be quantified in patiens chronically treated with antihistamines or amantadine, with the aim of determining the role of…
- Trial name
- NCT05504057
- Testing
- Antihistamine, Amantadine
- Where
- 2 sites in Spain
- Volunteers
- 140,660 people, healthy volunteers welcome
- Sponsor
- Consorci Sanitari de Terrassa
COVID-19 Infection
Study of WPV01 Compared With Placebo in Patients With Mild/Moderate COVID-19 Infection
A randomized, double-blind, placebo-controlled phase II clinical study to evaluate the efficacy and safety of WPV01 in patients with mild/moderate COVID-19 infection
- Trial name
- NCT05752175
- Testing
- WPV01
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Westlake Pharmaceuticals (Hangzhou) Co., Ltd.
SARS-CoV-2 Seroprevalence
ANC COVID-19 Surveillance
The purpose of this observational study is to determine the seroprevalence of SARS-CoV-2 antibodies in the community with pregnant women aged 15-49 years attending first antenatal care as the sentinel population.
- Trial name
- NCT07021807
- Where
- Zambia
- Volunteers
- 9,111 people, healthy volunteers welcome
- Sponsor
- Centre for Infectious Disease Research in Zambia
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