Clinical trials: COVID-19 Pneumonia
Covid19
Frailty in Elderly Patients With COVID-19
This is a multicentric retro-prospective observational study that wants to evaluate the relation between frailty and clinical outcomes in elderly patients with COVID-19.
- Trial name
- FRA-COVID (NCT04412265)
- Testing
- Relation between frailty and clinical outcomes in elderly patients with COVID-19.
- Where
- 6 sites in Italy
- Volunteers
- 1,344 people
- Sponsor
- University of Milano Bicocca
COVID-19
ApTOLL for the Treatment of COVID-19
There is a clear and urgent medical need of developing new medicinal products for COVID-19 since there are poor pharmacological tools to block the progression of patients to cytokine storm syndrome (CSS).
- Trial name
- NCT05293236
- Testing
- ApTOLL, Saline
- Where
- 4 sites in Spain
- Volunteers
- 5 people
- Sponsor
- Macarena Hernández Jiménez
Covid19, Anxiety
COVID 19 and Psychological Health: a Cross Sectional Study to Evaluate Anxiety and Depression in Covid-19 Patients
The covid-19 pandemic started to spread worldwide since December 2019. It promoted to an exaggerated psychological stress and anxiety in humans due to the intolerable symptoms higher than usual death of many infected patients.
- Conditions
- Covid19, Anxiety, Depression
- Trial name
- NCT04689464
- Where
- Iraq
- Volunteers
- 450 people
- Sponsor
- Alhasan Mujtaba Al-Mudhaffer
COVID-19
Duvelisib to Combat COVID-19
The exceedingly high mortality rates of severe and critical COVID-19 warrant the identification and evaluation of novel therapies that could potentially mitigate the advanced disease manifestations.
- Trial name
- NCT04372602
- Testing
- Duvelisib, Peripheral blood draw
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Washington University School of Medicine
Long COVID-19, Post-COVID-19 Syndrome
Effects of a Home-Based Exercise Intervention in Subjects with Long COVID
The current Coronavirus Disease 2019 (COVID-19) pandemic is the most severe health crisis of the 21st century. This is not only due to the deaths caused by the disease.
- Trial name
- NCT06073002
- Testing
- home-based concurrent exercise
- Where
- Austria
- Volunteers
- 20 people
- Sponsor
- University of Vienna
COVID-19
Study of AZD1222 for the Prevention of COVID-19 in Japan
The COVID-19 pandemic has caused major disruption to healthcare systems with significant socioeconomic impacts. Currently, there are no licensed preventions available against COVID-19 and accelerated vaccine development is…
- Trial name
- NCT04568031
- Testing
- AZD1222, 0.9% (w/v) saline
- Where
- 5 sites in Japan
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Safety, SARS-CoV2 Infection
Efficacy of Ivermectin in COVID-19
The newly emerged corona virus disease 2019 (COVID-19) has spread to all over the world, with recent estimates of more than 236 million cases diagnosed and led to 4.8 million deaths as November 20211 .Therapeutic approaches are…
- Conditions
- Safety, SARS-CoV2 Infection, Ivermectin Poisoning, Effect of Drug
- Trial name
- NCT05076253
- Testing
- Ivermectin
- Where
- Thailand
- Volunteers
- 72 people
- Sponsor
- Bangkok Metropolitan Administration Medical College and Vajira Hospital
Covid-19, Critical Illness
Optimizing Outcomes With Physical Therapy Treatment for IndividuALs Surviving an ICU Admission for Covid-19
Introduction: Survivors of acute respiratory failure develop persistent muscle weakness and deficits in cardiopulmonary endurance combining to limit physical functioning.
- Conditions
- Covid-19, Critical Illness, Post Intensive Care Unit Syndrome, Muscle Weakness
- Trial name
- OPTIMAL (NCT04412330)
- Testing
- ICU Recovery + Physical Therapy
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Kentucky
Chronic Pain, Covid19
Effects of COVID-19 in Chronic Pain
The aim of this study is to evaluate the effects of the COVID-19 pandemic on pain, stress, sleep and quality of life in patients with chronic musculoskeletal pain and the relationships between them.
- Trial name
- NCT04878900
- Testing
- Survey
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ufuk University
Covid19, SARS-CoV-2 Infection
A Study to Determine Safety and Immunogenicity of the Candidate COVID-19 Vaccine AZD1222 Delivered by Aerosol in Healthy Adult Volunteers
This study will test the COVID-19 vaccine candidate AZD1222 to investigate its safety, tolerability and capability of boosting immune responses both in the blood and the lung when administered to the respiratory tract, in…
- Trial name
- COVAXAER01 (NCT05007275)
- Testing
- 1x10^9 vp AZD1222, 5x10^9 vp AZD1222, 1x10^10 vp AZD1222
- Where
- United Kingdom
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Covid19, Neurocognitive Dysfunction
Long-term Neurocognitive and Psychiatric Consequences in Severe COVID-19 Survivors.
Long-term neurocognitive and psychiatric consequences of COVID-19 remain mostly unknown to date. It has been reported that coronaviruses cause direct central nervous system infection (Needham et al. 2020).
- Trial name
- NPQCOVID (NCT05019300)
- Testing
- Exposure: COVID-19 severity
- Where
- Chile
- Volunteers
- 80 people
- Sponsor
- Pontificia Universidad Catolica de Chile
COVID-19, Post COVID-19 Syndrome
Different Treatment Options Used for Post Covid-19 Syndrome
This study aimed to assess functioning during the recovery phase post-COVID-19 and to evaluate symptoms prolonging after COVID-19 infection and how to manage these symptoms.
- Conditions
- COVID-19, Post COVID-19 Syndrome, Ginkgo Biloba, Piracetam
- Trial name
- NCT07722000
- Testing
- Ginkgo biloba, Piracetam, Ginkgo biloba and Piracetam
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Beni-Suef University
COVID-19 Infection, Hematopoietic and Lymphatic System Neoplasm
Evaluation of Immunologic Response Following COVID-19 Vaccination in Children, Adolescents, and Young Adults With Cancer
This study evaluates immunologic response following COVID-19 vaccination in children, adolescents, and young adults with cancer. Vaccines work by stimulating the body's immune cells to respond against a specific disease.
- Conditions
- COVID-19 Infection, Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
- Trial name
- NCT05228275
- Testing
- Biospecimen Collection, Survey Administration
- Where
- 72 sites in United States
- Volunteers
- 549 people
- Sponsor
- Children's Oncology Group
Cognitive Impairment, Post-Acute Sequelae of SARS-CoV-2 Infection
Treatment of COVID-19 Post-acute Cognitive Impairment Sequelae With tDCS
After almost 2 years of pandemic, the consequences of the post-COVID syndrome, or PASC (Post Acute-Sequelae of Sars-CoV-2), have become a major challenge in the management of affected patients, generating costs for health…
- Conditions
- Cognitive Impairment, Post-Acute Sequelae of SARS-CoV-2 Infection, COVID-19
- Trial name
- PASC (NCT05389592)
- Testing
- Active tDCS and cognitive training
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo
Covid-19
Clinical Features and Risk Factors Associated With Worse Outcome in Patients Hospitalized for Covid-19 Pneumonia
The aim of the research is to improve patient management by rapidly identifying, based on the terrain and clinical and biological characteristics, those patients likely to present a severe form of ARDS at risk of leading to…
- Trial name
- NCT04362345
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
COVID-19, SARS-CoV-2
Treatment for COVID-19 in High-Risk Adult Outpatients
This is a randomized trial for the treatment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in high-risk adults not requiring hospital admission.The overarching goal of this study is to assess the…
- Trial name
- NCT04354428
- Testing
- Ascorbic Acid, Hydroxychloroquine Sulfate, Azithromycin
- Where
- 6 sites in United States
- Volunteers
- 289 people, healthy volunteers welcome
- Sponsor
- University of Washington
Coronavirus Infection
Hospitalization or Outpatient ManagEment of Patients With SRAS-CoV-2 Infection - Revised HOME-CoV Score Study
In the context of COVID-19 pandemic, identifying low-risk patients who can be safely treated at home and high-risk patients requiring hospitalization or even intensive care is crucial for Emergency Departments.
- Trial name
- NCT04657471
- Testing
- revised HOME-CoV score
- Where
- France
- Volunteers
- 1,300 people
- Sponsor
- University Hospital, Angers
COVID-19
A Study of Booster Immunization With COVID-19 Vaccine,Inactivated Co -Administration With Influenza Vaccine and Pneumococcal Polysaccharide Vaccine
This study is a single center , randomized ,controlled and open-label phase Ⅳclinical trial of the booster immunization with the third dose of inactivated COVID-19 vaccine(CoronaVac)manufactured by Sinovac Research \& Development…
- Trial name
- NCT05499351
- Testing
- Adult group in immunogenicity and safety study of combined immunization, Elderly group in immunogenicity and safety study of combined immunization, Adult group in safety observation study of combined immunization
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Sinovac Biotech Co., Ltd
Covid19
Safety, Tolerability and Efficacy of Amorphous Calcium Carbonate (ACC) Compared to Placebo and Best Available Care (BAT), for the Treatment of Moderate to Severe COVID-19 Patients.
This is a phase I/II study with Amorphous Calcium Carbonate (ACC) administered sublingual and in Inhalation concomitantly with BAT (Best Available Care) as Compared to Placebo and BAT for the treatment of Moderate to Severe…
- Trial name
- NCT04900337
- Testing
- AMOR 18 Powder & Inhalation
- Where
- 3 sites in Israel
- Volunteers
- 66 people
- Sponsor
- Amorphical Ltd.
COVID-19 Pandemic
Neural Network-Based Prediction in Critical COVID-19 Patients
In the context of an emerging pandemic without an established prognostic scoring system, deep learning approaches can be used to quickly develop empirical prognostic models.
- Trial name
- NCT07436572
- Testing
- Artificial Neural Network (ANN) Analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 113 people
- Sponsor
- University of Gaziantep
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