Clinical trials: COVID-19 Pneumonia
Covid19, Thrombosis
Apixaban for PrOphyLaxis of thromboemboLic Outcomes in COVID-19
Randomized, double-blinded, placebo-controlled trial comparing oral anticoagulation with placebo for community-dwelling patients with symptomatic COVID-19 infection and risk factors for thrombosis.
- Trial name
- APOLLO (NCT04746339)
- Testing
- Apixaban 2.5 MG
- Where
- 4 sites in Brazil
- Volunteers
- 411 people
- Sponsor
- Brazilian Clinical Research Institute
Long Haul COVID, Postural Orthostatic Tachycardia Syndrome
Ivabradine for Long-Term Effects of COVID-19 With POTS Cohort
The purpose of the study is three-fold. The primary aim is to identify the proportion of Long-Haul COVID (LHC) and non-LHC volunteers with relevant symptoms actually have postural orthostatic tachycardia syndrome (POTS).
- Trial name
- COVIVA (NCT05481177)
- Testing
- Ivabradine
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Uniformed Services University of the Health Sciences
Tuberculosis
Evaluation of Tuberculosis Treatment Outcomes
Tuberculosis (TB) is an infectious disease caused by Mycobacterium species grouped in the Mycobacterium tuberculosis complex. TB remains a major global health problem, despite the fact that there are drugs that can eradicate the…
- Trial name
- CLIO-TB (NCT06942975)
- Testing
- Patients with turberculosis
- Where
- Italy
- Volunteers
- 111 people
- Sponsor
- Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria
COVID-19, Venous Thromboembolism
Prevalence and Severity of Venous Thromboembolism in a General Population During the COVID-19 Pandemic
The purpose of this study is to investigate the prevalence of venous thromboembolism in a regional health care system (Region Östergötland, Sweden) before and during the SARS-COV-2 pandemic.
- Conditions
- COVID-19, Venous Thromboembolism, Pulmonary Embolism, Deep Vein Thrombosis
- Trial name
- NCT04400877
- Testing
- Diagnostic examination for venous thromboembolism
- Where
- Sweden
- Volunteers
- 7,795 people
- Sponsor
- University Hospital, Linkoeping
Acute Respiratory Distress Syndrome, Corona Virus Infection
Knowledge, Attitude and Practice of Dental Students About COVID-19
Coronavirus disease 2019 (abbreviated "COVID- 19") is a pandemic respiratory disease that is caused by a novel coronavirus and was first detected in December 2019 in Wuhan, China.
- Conditions
- Acute Respiratory Distress Syndrome, Corona Virus Infection, Acute Lung Injury, Fever
- Trial name
- NCT04449081
- Testing
- Knowledge, Attitude, Practice, Awareness, Preference
- Where
- Malaysia
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- Melaka Manipal Medical College
COVID 19
AiM COVID for Covid 19 Tracking and Prediction
University of Warwick (Coventry, UK) and NTUU "Igor Sikorsky" Kyiv Polytechnic Institute (Kyiv, Ukraine), together with ClickMedix LLC, have developed an app and a chatbot "AiM COVID" for efficient monitoring and mitigation of…
- Trial name
- NCT04354753
- Testing
- No Intervention
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Aarogyam UK
Covid-19
Relationship Between Social Status and Use of Healthcare Services During the Confinement Period Linked to the COVID-19 Epidemic
Epidemics have always affected the most disadvantaged social categories more intensely. This social inequality is expressed in the use of care and emergencies: greater frequency but also greater seriousness.
- Trial name
- NCT04703777
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Strasbourg, France
COVID, ARDS
One-year Outcomes in Survivors of the Severe COVID-19 Pneumonia (CO-Qo-ICU)
Many of the patients hospitalized for a severe form of SARSCoV-2 respiratory impairment require prolonged intensive care that can be complicated in the short term, In the medium and long term, physical and psychological sequelae…
- Conditions
- COVID, ARDS, Quality of Life
- Trial name
- CO-Qo-ICU (NCT04401111)
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Mental Health, COVID-19
Leveraging Community Health Workers to Combat COVID-19 and Mental Health Misinformation in Haiti, Malawi, and Rwanda
Partners In Health (PIH), in collaboration with Harvard Medical School, aims to develop and evaluate an SMS-based intervention for Community Health Workers (CHWs) to combat COVID-19 and mental health-related misinformation in…
- Conditions
- Mental Health, COVID-19, Misinformation
- Trial name
- NCT05997511
- Testing
- Card-Sorting Activity (Pre-intervention design), SMS Crafting (Pre-intervention design), SMS Messaging
- Where
- 3 sites in Haiti, Malawi and 1 more
- Volunteers
- 5,109 people
- Sponsor
- Harvard Medical School (HMS and HSDM)
COVID-19 Infection, COVID-19-Associated Acute Respiratory Distress Syndrome
Study of Cord Blood Derived Mesenchymal Stem Cells for Treatment of Moderate, Severe or Critical Pneumonia
This is a phase I trial followed by a phase II randomized trial. The purpose of phase I study is the feasibility of treating patients with acute respiratory distress syndrome (ARDS) related to COVID-19 infection (COVID-19) with…
- Conditions
- COVID-19 Infection, COVID-19-Associated Acute Respiratory Distress Syndrome, Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
- Trial name
- NCT04565665
- Testing
- Best Practice, Mesenchymal Stem Cell
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- M.D. Anderson Cancer Center
Covid19
Core Warming in COVID-19 Patients Undergoing Mechanical Ventilation
The purpose of the proposed pilot study is to determine if core warming improves respiratory physiology of mechanically ventilated patients with COVID-19, allowing earlier weaning from ventilation, and greater overall survival.
- Trial name
- NCT04494867
- Testing
- Core Warming, Standard of Care
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Sharp HealthCare
Metabolic Syndrome, Emotional Eating
The Relationship Between COVID-19 Anxiety Level and Emotional Eating in Individuals With Metabolic Syndrome
The aim was to determine the coronavirus anxiety levels and emotional eating status of cases with diagnosis of MetS according to diagnostic criteria published by the International Diabetic Federation (IDF) in 2005 and healthy…
- Conditions
- Metabolic Syndrome, Emotional Eating, COVID-19
- Trial name
- COVID-19 (NCT04912934)
- Testing
- A survey form was applied to individuals included in the study face-to-face.
- Where
- Turkey (Türkiye)
- Volunteers
- 214 people
- Sponsor
- Ordu University
SARS-CoV-2, COVID-19
VA Remote and Equitable Access to COVID-19 Healthcare Delivery (VA-REACH TRIAL)
We propose a 3-arm RCT to determine the efficacy of hydroxychloroquine or azithromycin in treating mild to moderate COVID-19 among Veterans in the outpatient setting.
- Trial name
- VA-REACH (NCT04363203)
- Testing
- Hydroxychloroquine, Azithromycin
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Salomeh Keyhani MD
Covid19, Pneumonia, Viral
Aralast NP With Antiviral Treatment and Standard of Care Versus Antiviral Treatment With Standard of Care in Hospitalized Patients With Pneumonia and COVID-19 Infection
This is a Randomized, Open-Label Study of the Efficacy and Safety of Aralast NP Infusion Therapy with Antiviral Treatment and standard of care versus Antiviral Treatment and standard of care (control group) in Hospitalized…
- Trial name
- NCT04675086
- Testing
- alpha1-proteinase inhibitor, Antiviral Agents
- Where
- United States
- Sponsor
- Blessing Corporate Services, Inc
Patients With COVID-19 Pneumonia Will Allow to Detect an Absolute Reduction in the Rate of Respiratory-failure
Defibrotide in COVID-19 Pneumonia
Phase II, prospective, interventional, single-arm, multicentric, open label trial, with a parallel retrospective collection of data on not treated patients from IRCCS, San Raffaele Scientific Institute included in the…
- Trial name
- DEFI-VID19 (NCT04335201)
- Testing
- Defibrotide Injection
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- IRCCS San Raffaele
COVID-19, SARS-CoV-2 Infection
Nasal and Pulmonary Nitric Oxide Output in COVID-19 Infection
A Study of the relation of COVID-19 infection and its severity to upper and lower airway nitric oxide, upper airway viral load and lung function.
- Trial name
- NCT04728919
- Where
- Finland
- Volunteers
- 82 people
- Sponsor
- Tampere University Hospital
Venous Thromboembolism, covid19
Hemostasis and Inflammation in COVID-19 Patients With Venous and Arterial Thrombotic Complications
The study is aimed at assessing the role of the activity of high-risk markers of thrombotic events (MCP-1, MIP1α, IP-10, phosphatedylserine, calreticulin) on the development of thrombotic complications in patients with COVID -19.
- Conditions
- Venous Thromboembolism, covid19, Thrombosis
- Trial name
- NCT05143567
- Testing
- standard of care anticoagulation in absence of thrombotic complications, standard of care anticoagulation in presence of thrombotic complications, standard of care anticoagulation in combination with elastic compression
- Where
- Russia
- Volunteers
- 150 people
- Sponsor
- Ryazan State Medical University
COVID-19, Patient Discharge
Symptom Clusters and Risk Factors of COVID-19 Patients
Aim and objectives: To clarify the types, composition, distribution characteristics and risk factors of symptom clusters experienced by discharged patients with COVID-19, to lay the foundation for effective symptom management.
- Conditions
- COVID-19, Patient Discharge, Symptoms and Signs
- Trial name
- NCT05556707
- Where
- China
- Volunteers
- 384 people
- Sponsor
- RenJi Hospital
Nitric Oxide, COVID-19
Inhaled NO in Surgical Patients With Recent COVID-19 Infection
The aim of this study is to evaluate the effect of perioperative inhalation of NO on reducing the incidence of postoperative pulmonary complications in patients with recent COVID-19 infection, and to evaluate whether inhaled NO…
- Conditions
- Nitric Oxide, COVID-19, Surgery, Postoperative Complications
- Trial name
- INORDINATE (NCT05721144)
- Testing
- Nitric Oxide Gas
- Where
- China
- Volunteers
- 660 people
- Sponsor
- Xijing Hospital
Severe COVID-19 Disease
RAPA-501-Allo Therapy of COVID-19-ARDS
The first-in-human Phase 1 study component will evaluate two dose levels of RAPA-501-ALLO off the shelf cells in patients with COVID-19-related ARDS, with key endpoints of safety, biologic and potential disease-modifying effects.
- Trial name
- NCT04482699
- Testing
- RAPA-501-Allo off-the-shelf Therapy of COVID-19
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Rapa Therapeutics LLC
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