Clinical trials: COVID-19 Pneumonia
Healthy Participant
A Study to Learn How the Study Medicine Called Ibuzatrelvir is Taken up Into the Blood in Healthy Chinese Adults
A study to learn how the study medicine called Ibuzatrelvir is taken up into the blood in healthy Chinese adults.
- Trial name
- NCT07235137
- Testing
- Ibuzatrelvir
- Where
- China
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer
Acute Respiratory Failure
The Tele-Rehab MV Cluster Stepped-Wedge Randomized Clinical Trial
To evaluate, through a randomized clinical trial in groups/clusters (stepped wedge), the impact of specific bundles for disability prevention and early rehabilitation, focused on 3 domains (ICU, ward and post-discharge), on…
- Trial name
- Tele-Rehab MV (NCT06343545)
- Testing
- Standard of Care, Disability Prevention and Rehabilitation
- Where
- 20 sites in Brazil
- Volunteers
- 1,916 people
- Sponsor
- Hospital Israelita Albert Einstein
Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Tocilizumab for Patients With Cancer and COVID-19 Disease
This phase II expanded access trial will study how well tocilizumab works in reducing the serious symptoms including pneumonitis (severe acute respiratory distress) in patients with cancer and COVID-19.
- Conditions
- Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm, Pneumonia, Pneumonitis
- Trial name
- NCT04370834
- Testing
- Tocilizumab
- Where
- 5 sites in United States
- Volunteers
- 1 people
- Sponsor
- National Cancer Institute (NCI)
COVID-19 Infection
Clinical Trial to Evaluate the Efficacy and Safety of an Immunomodulatory Therapy for the Treatment of Patients With Moderate to Severe COVID-19 Infection
An Open-label, prospective, randomized, comparative, multiple doses applied in addition to the standard of care treatment of patients with moderate to severe COVID-19 infection
- Trial name
- NCT04374032
- Testing
- metenkefalin + tridecactide, The standard of care
- Where
- 5 sites in Bosnia and Herzegovina
- Volunteers
- 120 people
- Sponsor
- Bosnalijek D.D
HIV Infections, Covid19
Bidirectional, Upbeat Communication and Differentiated, Distanced Care for Young People
Sub Saharan Africa is home to only 12% of the population, but accounts for approximately 70% of the global burden of HIV infection and 84% of infections among young people aged 10-24 years.
- Conditions
- HIV Infections, Covid19, Health Care Utilization, Gender-based Violence
- Trial name
- BUDDY (NCT04781400)
- Testing
- Mobile phone support, Remote service delivery model
- Where
- South Africa
- Volunteers
- 536 people, healthy volunteers welcome
- Sponsor
- Desmond Tutu HIV Foundation
Covid19
Thymalfasin (Thymosin Alpha 1) to Treat COVID-19 Infection
It is our hypothesis that a course of Ta1 administered to hospitalized individuals with COVID-19 infection and lymphocytopenia will improve the time to recovery (primary objective) and severity of infection (secondary objectives)…
- Trial name
- Ta1 (NCT04487444)
- Testing
- Thymalfasin
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Rhode Island Hospital
COVID-19, SARS-CoV2 Infection
Effect of IMMUNEPOTENT-CRP on Serum Pro-Inflammatory Cytokines in Mild to Moderate COVID-19
In this study, the effects of IMMUNEPOTENT-CRP (I-CRP), a dialyzable leukocyte extract (DLE) derived from bovine spleen cells, on the levels of key inflammatory cytokines in outpatients with COVID-19 were examined.
- Trial name
- ICRPDLECOVID (NCT06676709)
- Testing
- IMMUNEPOTENT-CRP (I-CRP)
- Where
- 2 sites in Mexico
- Volunteers
- 80 people
- Sponsor
- Universidad Autonoma de Nuevo Leon
SARS-CoV-2, Covid19
Pathological Findings of Fatal COVID-19
The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a new coronavirus discovered in December 2019 in Wuhan, China and currently responsible of a worldwide outbreak and the death of more than 55,000 patients in…
- Conditions
- SARS-CoV-2, Covid19, Pathology, Intensive Care Units
- Trial name
- HISTOCOVID (NCT04675281)
- Testing
- 2 post-mortem transcutaneous lung biopsies (1 anterior ; 1 posterior) using anatomical landmarks
- Where
- 44 sites in France
- Volunteers
- 170 people
- Sponsor
- Nantes University Hospital
COVID-19, Vaccine
Evaluation of Menstrual Irregularities and Abnormal Uterine Bleeding After Covid-19 Vaccine
Covid-19 vaccines offered a good opportunity to counteract the spread of Sars-Cov-2 infection among the general population, reducing significantly both morbidity and mortality.
- Conditions
- COVID-19, Vaccine, Menstrual Irregularity, Menopausal Bleeding
- Trial name
- MECOVAC-1 (NCT05083065)
- Testing
- Covid-19 vaccine
- Where
- Italy
- Volunteers
- 369 people, healthy volunteers welcome
- Sponsor
- Università degli Studi dell'Insubria
Covid19
The Lymphoma and Leukemia Society Amended COVID-19 Registry
The LLS COVID-19 Registry is being amended to invite people who participated in the LLS COVID-19 Registry and did not develop antibodies after receiving a complete COVID-19 vaccination, as well as people with blood cancer who did…
- Trial name
- NCT04794387
- Testing
- Amended LLS COVID-19 Registry
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Blood Cancer United
Asthma, Asthma Attack
Optimisation of ASthma In Those With Uncontrolled Symptoms (OASIS)
A digital tool, called ReferID has been developed to facilitate the review of asthma patients. It aims to assist in the identification of patients with uncontrolled and/or severe asthma and to ensure a timely referral to…
- Conditions
- Asthma, Asthma Attack, Asthma Persistent, Covid19
- Trial name
- OASIS (NCT04941001)
- Testing
- ReferID
- Where
- United Kingdom
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Covid19, SARS-CoV Infection
Olfactory Training for Olfactory Dysfunction After Coronavirus Disease - 19 (COVID-19)
It is a randomized controlled clinical trial study that aims to follow a sample of individuals with persistent olfactory dysfunction post-COVID-19.
- Conditions
- Covid19, SARS-CoV Infection, Olfactory Disorder, Anosmia
- Trial name
- NCT04764981
- Testing
- Essence oils
- Where
- Brazil
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Universidade do Estado do Pará
Covid19
Study to Evaluate a Single Intranasal Dose of STI-2099 (COVI-DROPS™) in Outpatient Adults With COVID-19 (UK)
This is a double-blind study designed to investigate the efficacy, safety and PK of a single dose of COVI-DROPS or matched placebo in outpatient adults who have tested positive for COVID-19 and are either asymptomatic or have…
- Trial name
- NCT04900428
- Testing
- COVI-DROPS
- Where
- United Kingdom
- Volunteers
- 179 people
- Sponsor
- Sorrento Therapeutics, Inc.
Corona Virus Infection, Critical Illness
The Change of Critical Patient Managements and Subsequent Influences Under Epidemic of Coronavirus Disease 19 (COVID-19)
In the ER of National Taiwan University Hospital, the critical patients are treated (including tracheal intubation and cardiopulmonary resuscitation) in either resuscitation area or negative pressure isolation rooms based on the…
- Trial name
- NCT04479332
- Testing
- Tracheal intubation and cardiopulmonary resuscitation
- Where
- Taiwan
- Volunteers
- 198 people
- Sponsor
- National Taiwan University Hospital
COVID-19
Discussing COVID-19 Vaccines in Private Facebook Groups
As the COVID-19 pandemic persists, a sizable proportion of the U.S. population remains unvaccinated and at high risk of death and serious illness from COVID-19.
- Trial name
- NCT05422898
- Testing
- Gist messages on COVID-19 vaccination, COVID-19 vaccine information
- Where
- United States
- Volunteers
- 508 people, healthy volunteers welcome
- Sponsor
- George Washington University
COVID-19 Infection, COVID-19-Associated Acute Respiratory Distress Syndrome
Study of Cord Blood Derived Mesenchymal Stem Cells for Treatment of Moderate, Severe or Critical Pneumonia
This is a phase I trial followed by a phase II randomized trial. The purpose of phase I study is the feasibility of treating patients with acute respiratory distress syndrome (ARDS) related to COVID-19 infection (COVID-19) with…
- Conditions
- COVID-19 Infection, COVID-19-Associated Acute Respiratory Distress Syndrome, Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
- Trial name
- NCT04565665
- Testing
- Best Practice, Mesenchymal Stem Cell
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- M.D. Anderson Cancer Center
Covid19
The Nanowear Wearable Covid-19 Observational and Analysis Trend
The NanoCOAT study is a multi-center, prospective, non-randomized, feasibility, observational, non-significant risk study. The NanoCOAT study will enroll a minimum of 10 and a maximum of 100 subjects in a potential for a…
- Trial name
- NanoCOAT (NCT04717024)
- Testing
- Observational Study - no intervention
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Nanowear Inc.
SARS-CoV2 Infection, Viral Load
Viral Kinetics of SARS-CoV-2 in Patients With COVID-19 in the Intensive Care Unit Undergoing Dental Procedures
The prevalence and clinical relevance of viremia in patients with COVID-19 have not been well investigated. Seeking to understand the need for dentistry to perform bloody procedures in critically ill patients with COVID-19…
- Conditions
- SARS-CoV2 Infection, Viral Load, Oral Diseases, Dental Treatment
- Trial name
- VKSPCICUDP (NCT05311410)
- Testing
- Non-bloody dental procedures (control group), Bloody dental procedures (study group)
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo General Hospital
COVID19, Fertility Issues
COVID-19 in ART: Perception and Experience
Non-urgent medical care, such as fertility treatments, has been massively postponed during the past weeks due to the COVID19 pandemic.
- Conditions
- COVID19, Fertility Issues, ART
- Trial name
- COVAPEX (NCT04456010)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 600 people
- Sponsor
- University Hospital, Montpellier
Covid-19, Health Personnel
Seroconversion Among Staff at a Large Acute Care Hospital in Denmark During the COVID-19 Pandemic
The aim of this study is to apply serology testing methods for SARS-CoV2 antibodies in samples collected from HCWs in an acute hospital.
- Conditions
- Covid-19, Health Personnel, Personnel, Hospital
- Trial name
- NCT04431310
- Testing
- Serial seroconversion measurements in hospital employees during the COVID-19 pandemic
- Where
- 2 sites in Denmark
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Nordsjaellands Hospital
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