Clinical trials: COVID-19 Pneumonia
Covid19, Pneumonia, Viral
Vascular Abnormalities Detected With Chest CT in COVID-19
Chest computed tomography of patients having coronavirus disease (COVID-19) will be analyzed with regards to vascular abnormalities (pulmonary embolism and vascular thickening), and their association with lung inflammation.
- Conditions
- Covid19, Pneumonia, Viral, Pulmonary Embolism
- Trial name
- COVID-CAVA (NCT04824313)
- Testing
- Chest CT, Chest CTA
- Where
- Switzerland
- Volunteers
- 1,000 people
- Sponsor
- Salah D. Qanadli
Long COVID, Dysautonomia
Mindfulness in Post Acute Sequelae of SARS-CoV-2 Infection (PASC) Dysautonomia
The current pilot study will recruit participants experiencing new, returning, or ongoing symptoms related to COVID-19 illness for at least four weeks after being first infected with SARS-CoV-2.
- Trial name
- NCT05566379
- Testing
- Mindfulness - Mindful Awareness Practices ( MAPs)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, Los Angeles
COVID-19
Comparison of Two Different Doses of Bemiparin in COVID-19
Patients requiring hospitalization due to COVID-19 pneumonia (non-severe) will be randomized to standard prophylactic doses or full therapeutic dose of bemiparin (a LMWH) for 10 days.
- Trial name
- BEMICOP (NCT04604327)
- Testing
- Bemiparin sodium
- Where
- 12 sites in Spain
- Volunteers
- 164 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
COVID-19
Study on Sequential Immunization of Inactivated COVID-19 Vaccine and Recombinant COVID-19 Vaccine (Ad5 Vector) in Elderly Adults
This is a randomized, observer-blind, parallel-controlled study, for evaluation of safety and immunogenicity of sequential immunization of a recombinant COVID-19 vaccine (adenovirus type 5 vector) in Chinese healthy adults aged…
- Trial name
- NCT04952727
- Testing
- Recombinant SARS-CoV-2 Ad5 vectored vaccine, Inactive SARS-CoV-2 vaccine (Vero cell)
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Jiangsu Province Centers for Disease Control and Prevention
COVID19
Defibrotide as Prevention and Treatment of Respiratory Distress and Cytokine Release Syndrome of Covid 19.
Protection of endothelial dysfunction by intravenous infusion of Defibrotide (Defitelio), expected to decrease inflammation and expression of adhesion molecules in the endothelium, leukocyte tissue infiltration and epithelial…
- Trial name
- DEFACOVID (NCT04348383)
- Testing
- Defibrotide
- Where
- 6 sites in Spain
- Volunteers
- 156 people
- Sponsor
- Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia
Antibiotic Resistant Infection, COVID-19
The Impact of Covid-19 Hospital Care on the Prevalence of MDRO in Indonesia
The effect of the COVID-19 pandemic on the emergence and spread of antibiotic-resistant bacteria is largely unknown, especially in low-resource settings.
- Trial name
- NCT05293483
- Where
- 2 sites in Indonesia
- Volunteers
- 1,110 people
- Sponsor
- Erasmus Medical Center
Covid-19
Evaluation of Additional Treatments for COVID-19: a Randomized Trial in Niger
The purpose of this study is to assess whether lopinavir/ritonavir (or eventually other antiviral drugs) is effective at reducing the rate of hospitalization among confirmed COVID-19 cases treated as outpatients.
- Trial name
- TRASCOV (NCT04409483)
- Testing
- Lopinavir-Ritonavir Drug Combination, Standard Care
- Sponsor
- Epicentre
Infections, Covid19
Rosmalip® for Cancer Infections Prevention
This study is designed to assess the safety and efficacy of Rosmalip® nutritional supplement compared to placebo in subjects with solid cancer for the prevention of infections including COVID-19.
- Conditions
- Infections, Covid19, Cancer
- Trial name
- OnCOVInf (NCT05080920)
- Testing
- Rosmalip®
- Where
- Spain
- Volunteers
- 109 people
- Sponsor
- Fundación Investigación E Innovación Biomédica Hospital Universitario Infanta Sofia-Henares
SARS-CoV-2 Infection, Post-acute Sequelae of SARS-CoV-2
The Canadian Respiratory Research Network Long COVID-19 Study
Preliminary studies suggest that COVID-19 causes long-term lung damage, even in young, otherwise healthy people who did not need to go to hospital or the ICU.
- Trial name
- NCT05181670
- Where
- 8 sites in Canada
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
COVID-19, SARS-CoV-2
Effect of Hydroxychloroquine in COVID-19 Positive Pregnant Women
COVID-19 was declared a pandemic on March 11th. Efforts to save lives are essential as we will face increasing morbidity with rising demands on health care resources.
- Conditions
- COVID-19, SARS-CoV-2, Pregnant Women, Hydroxychloroquine
- Trial name
- HyPreC (NCT04354441)
- Testing
- hydroxychloroquine sulfate 200 MG
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
Covid19
Effectiveness of Ivermectin in SARS-CoV-2/COVID-19 Patients
Background: The first case of Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were diagnosed in Wuhan, China in 2019.
- Trial name
- NCT04739410
- Testing
- Ivermectin
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- FMH College of Medicine and Dentistry
Covid19
Detection of SARS-CoV-2 (COVID-19) by SERS Spectroscopy Combined With Artificial Intelligence
SARS-CoV-2 infection was identified as responsible for several cases of pneumonia and acute respiratory distress syndromes described in Wuhan, Hubei Province, China in December 2019.
- Trial name
- Kaïssa Covid (NCT04786197)
- Where
- France
- Volunteers
- 712 people
- Sponsor
- Fondation Hôpital Saint-Joseph
COVID-19
Treatment of Angiotensin Peptide (1-7) for COVID-19
Novel Coronavirus is reported to cause COVID-19, recently. It's known that this virus uses ACE (angiotensin converting enzyme) 2 receptors to enter human cells and also blocks the activity of ACE 2.
- Trial name
- NCT04375124
- Testing
- Biological/Vaccine: Angiotensin peptide (1-7) derived plasma
- Where
- Turkey (Türkiye)
- Volunteers
- 9 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
COVID-19 Pneumonia
Efficacy of the Early Prone-positioning in Hospitalized Patients With Mild Covid-19 Pneumonia
The study aims to evaluate if the early prone-positioning in awake patients with mild Covid-19 pneumonia can reduce the need of high-flow oxygen-therapy, invasive or non-invasive ventilation and prevent the worsening of clinical…
- Trial name
- EpCOT (NCT05008380)
- Testing
- prone positioning
- Where
- Italy
- Volunteers
- 96 people
- Sponsor
- University of Milano Bicocca
Pandemic, COVID-19, Adult ALL
Emotional and Physical Health Status of Adults
To investigate the comparison of differences between emotional and physical health status of adults in COVID-19 isolation period and controlled normalization period.
- Trial name
- NCT05206903
- Testing
- Questionnaires
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
SARS-COV2 Infection, COVID-19 Disease
COVID-19 Disease and Coagulopathy: Assessment of Clotting Factor Levels in Patients With SARS-CoV-2 Infection
Effect of Covid-19 disease in clotting factors levels in hospitalized patients
- Conditions
- SARS-COV2 Infection, COVID-19 Disease, Hospitalized Patients
- Trial name
- NCT04787510
- Testing
- low molecular weight Heparin as standard of care treatment
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- University Hospital, Ioannina
Convalescent Plasma, COVID-19
Efficacy and Safety of COVID-19 Convalescent Plasma
Administration of convalescent plasma obtained from donors with prior documented SARS-CoV-2 infection
- Conditions
- Convalescent Plasma, COVID-19, SARS-CoV 2
- Trial name
- NCT04397523
- Testing
- anti-SARS-CoV-2 convalescent plasma
- Where
- North Macedonia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Institute for Transfusion Medicine of RNM
Metabolic Syndrome, Overweight and Obesity
Age-related Post-lockdown BMI Variations
The COVID-19 lockdown has represented an unedited model of increased metabolic risk in all age groups, due to negative changes in dietary habits, physical activity, lifestyle.
- Trial name
- COVIDLOCKMET01 (NCT05430542)
- Where
- Italy
- Volunteers
- 298 people, healthy volunteers welcome
- Sponsor
- University of Bari
COVID 19 Disease
Photobiomodulation Therapy Versus Integrated Myofascial Release Therapy Techniques In Patients With COVID-19 With Follow-Up Telerehabilitation
Objective: To compare low-level laser therapy and myofascial release in reducing inflammation and functional recovery in critically ill COVID-19 patients with 3-month home-based telerehabilitation assessment.
- Trial name
- PBM in COVID19 (NCT06795841)
- Testing
- Photobiomodulation, Myofascial release therapy, traditional chest physiotherapy
- Where
- Egypt
- Volunteers
- 102 people
- Sponsor
- Beni-Suef University
COVID-19, Coronavirus Infection
Relative Bioavailability Study of CX2101A for the Treatment of COVID-19
The study comprises three parts: single ascending dose (SAD) studies of CX2101A tablets at 40 mg, 100 mg, and 160 mg; a relative bioavailability (BA) study comparing single-dose administration of 100 mg CX2101A tablets and…
- Trial name
- NCT06864182
- Testing
- CX2101A tablet, CX2101A enteric-coated tablet
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Heronova Pharmaceuticals
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