Clinical trials: COVID-19 Pneumonia
COVID-19, Maternal Vaccine Exposure
Priming of the NEonatal Immune System by Transfer of Maternal Immunity
Newborn babies and infants are susceptible to infections as their immune system is still immature. Maternal immune factors for example antibodies and immune cells mitigate this vulnerability.
- Conditions
- COVID-19, Maternal Vaccine Exposure, Respiratory Infections in Children
- Trial name
- NEST (NCT05429047)
- Testing
- Tozinameran, COVID-19, No SARS-CoV-2 exposure
- Where
- Germany
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Hannover Medical School
COVID-19, Inpatient
Virtual Reality Therapy Influence on Heart Rate Variability of Inpatients With COVID-19
The end of 2019 saw the emergence of a new human coronavirus (COVID-19) spread rapidly around the world and has a high degree of lethality.
- Trial name
- NCT04537858
- Testing
- Virtual reality therapy first, Conventional therapy first
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- University of Sao Paulo
COVID 19
Impact of Nasal Saline Irrigations on Viral Load in Patients With COVID-19
Nasal saline irrigations are a safe and commonly used mechanism to treat a variety of sinonasal diseases including sinusitis, rhinitis, and upper respiratory tract infections.
- Trial name
- NCT04347538
- Testing
- Saline Nasal Irrigation
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Vanderbilt University Medical Center
Post-COVID-19, Healthy Participants
Effects of Post-COVID-19 on Quadriceps Femoral Muscle-tendon Unit
The physiological/biomechanical characteristics related to muscle and tendon architecture and their possible relationship with the loss of muscle strength and fatigue in patients who were infected with COVID-19 are totally…
- Trial name
- NCT04961255
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Brasilia
Covid19
Vitamin D3 Levels in COVID-19 Outpatients From Western Mexico
The immunomodulatory effects of vitamin D are known to be beneficial in viral infections, it is also known that its deficiency is associated with a worse prognosis of COVID-19.
- Trial name
- NCT04793243
- Testing
- Vitamin D3
- Where
- Mexico
- Volunteers
- 42 people
- Sponsor
- University of Guadalajara
COVID-19, Chronic Heart Failure
Intermittent Hypoxic-hyperoxic Training in Patients With Cardiovascular Pathology After COVID-19 Infection.
Aim of this prospective, interventional, single-center, randomized study is to evaluate the efficacy and safety of intermittent hypoxic-hyperoxic training (IHHT) as a rehabilitation method in patients with cardiovascular…
- Conditions
- COVID-19, Chronic Heart Failure, Hypertension, Arrhythmia
- Trial name
- NCT05379608
- Testing
- Intermittent hypoxic-hyperoxic training, Intermittent hypoxic-hyperoxic training/control
- Where
- Russia
- Volunteers
- 43 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Accelerated Phase CML, BCR-ABL1 Positive, Acute Lymphoblastic Leukemia
SARS-CoV-2 Donor-Recipient Immunity Transfer
This study investigates whether donors with previous exposure to COVID-19 can pass their immunity by hematopoietic (blood) stem cell transplant (HCT) donation to patients that have not been exposed.
- Conditions
- Accelerated Phase CML, BCR-ABL1 Positive, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Chronic Lymphocytic Leukemia
- Trial name
- NCT04666025
- Testing
- Biospecimen Collection, Diagnostic Laboratory Biomarker Analysis, Electronic Health Record Review
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- City of Hope Medical Center
COVID-19, Acute Respiratory Distress Syndrome
Low-Level Laser Therapy Treatment of Lung Inflammation in Post-COVID-19 Recovery
An informational evaluation of COVID-19 patients who receive low-level laser therapy in addition to a normal regimen of treatment for symptoms associate with COVID-19.
- Trial name
- NCT05258617
- Testing
- LLLT Photobiomodulation
- Where
- 7 sites in United States
- Volunteers
- 5 people
- Sponsor
- Ward Photonics LLC
COVID19
Role of Immune and Inflammatory Response in Recipients of Allogeneic Haematopoietic Stem Cell Transplantation (SCT) Affected by Severe COVID19
COVID19 pandemic currently represents a public health emergency. Based on current data, 15% of the affected individuals will develop a severe form of the disease requiring admission to hospital and respiratory support.
- Trial name
- (COVID19_BMT) (NCT04349540)
- Testing
- no intervention
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
SARS-CoV2, COVID-19
A Study to Evaluate VXA-CoV2-3.3 COVID-19 Vaccine Against Currently Approved/Authorized mRNA COVID-19 Injectable Booster Vaccine in Adults Previously Immunized Against COVID-19 Infection
The primary objective of the study is to determine the relative efficacy of the investigational oral severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) vaccine tablet VXA-CoV2-3.3 compared to a currently recommended…
- Trial name
- NCT06672055
- Testing
- VXA-CoV2-3.1, COMIRNATY®, VXA-CoV2-3.3
- Where
- 145 sites in United States
- Volunteers
- 5,485 people
- Sponsor
- Vaxart
COVID-19 Pneumonia, Mortality
Factors Affecting Mortality in Covid-19 Disease
The coronavirus disease-19 (COVID-19), defined by the reporting of pneumonia cases of unknown etiology at the end of 2019 in Wuhan, China, has spread worldwide, causing millions of deaths.
- Trial name
- NCT06043115
- Testing
- covid-19 survival cohort, covid-19 mortality cohort
- Where
- Turkey (Türkiye)
- Volunteers
- 619 people
- Sponsor
- Melike Cengiz
SARS-CoV-2
Prevalence of SARS-CoV-2 Genome in Tears of Asymptomatic and Moderately Symptomatic COVID-19 Patients
To evaluate the prevalence of SARS-CoV-2 genome in patients with asymptomatic and moderately symptomatic COVID19.
- Trial name
- COVIDEYE (NCT04654325)
- Testing
- conjunctival swab
- Where
- France
- Volunteers
- 534 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
COVID-19
Methodist Health System COVID-19 Patient Registry
This is a prospective cohort observational registry study that will include data on all patients who are treated at MHS facilities for COVID-19.
- Trial name
- NCT04477889
- Testing
- Treatment for COVID-19
- Where
- United States
- Volunteers
- 550 people
- Sponsor
- Methodist Health System
Covid19, type1diabetes
Covid-19 Infection and New Onset Type 1 Diabetes
Although recognized as an autoimmune disease the etiology of type 1 diabetes remains unknown. Virus infections has been suggested as a possible agent triggering the autoimmune reaction finally resulting in beta-cell destruction…
- Trial name
- NCT04623697
- Where
- Denmark
- Volunteers
- 600 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
COVID-19 Acute Respiratory Distress Syndrome
Efficacy of Canrenone as add-on Treatment in Moderate to Severe ARDS in COVID-19
The main aim of the study is to estimate the potential efficacy of i.v. canrenone as add-on therapy on maximal medical treatment versus maximal medical treatment alone in treating moderate-to-severe ARDS due to SARS-CoV-2.
- Trial name
- MINECRAFT (NCT04977960)
- Testing
- Potassium Canrenoate
- Volunteers
- 180 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Neuromuscular Blockade, Human Characteristics
Sparing in Neuromuscular Blockade in COVID 19 ICU
This is a retrospective case-controlled study of the effect of the use of a neuromuscular blockade (NMB) monitor on the consumption of NMB agents in patients under mechanical ventilation in the context of COVID-19.
- Conditions
- Neuromuscular Blockade, Human Characteristics, Complication of Medical Care, Intensive Care Unit Acquired Weakness
- Trial name
- TOF-COVID (NCT04459533)
- Testing
- TOF protocol
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Hospices Civils de Lyon
COVID-19
Clinical Trial of Safety and Immunogenicity of Recombinant SARS-CoV-2 S-Trimer Vaccine (CHO Cells) as Booster Vaccination in Populations Aged 18 to 59 Years
Increased immune escape of emerging SARS-CoV-2 variants and waning neutralizing antibody levels over time indicate the importance of COVID-19 vaccine booster dose.
- Trial name
- NCT05716347
- Testing
- the recombinant SARS-CoV-2 S-Trimer vaccine/inactivated SARS-CoV-2 vaccine
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Binhui Biopharmaceutical Co., Ltd.
COVID-19
Dimolegin® (60 mg) for Patients With Moderate COVID-19: A Non-Interventional Study
A multicenter, open-label, non-interventional study evaluates the safety and tolerability of oral Dimolegin® (60 mg once daily) for thromboprophylaxis in hospitalized adults (≥18 years) with moderate COVID-19 in real clinical…
- Trial name
- NCT07134738
- Testing
- Dimolegin
- Where
- 6 sites in Russia
- Volunteers
- 184 people
- Sponsor
- Avexima Diol LLC
COVID - 19
Persistent COVID-19 Symptoms in Minia
Objective This study aims to identify the nature and prevalence of persistent symptoms in patients discharged from Minya University hospitals in Egypt after recovery from COVID-19, the severity of these symptoms, and the possible…
- Trial name
- NCT06787755
- Where
- Egypt
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Covid-19
CLBS119 for Repair of COVID-19 Induced Pulmonary Damage
This clinical trial will explore the safety and potential efficacy of CLBS119 for the repair of COVID-19 induced pulmonary damage in adults.
- Trial name
- NCT04522817
- Testing
- CLBS119
- Where
- United States
- Sponsor
- Lisata Therapeutics, Inc.
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.