Clinical trials: COVID-19 Pneumonia
COVID-19 Pandemic
A PhaseⅡ Study to Evaluate the Safety & Immunogenicity of SARS-CoV-2 Alpha/Beta/Delta/Omicron Variants COVID-19 Vaccine
This study is a randomized, double-blind, placebo-controlled Phase II clinical trial to evaluate the safety and immunogenicity of SCTV01E in population of different ages who have been vaccinated against COVID-19.
- Trial name
- SCTV01E (NCT05652543)
- Testing
- SCTV01E
- Where
- 4 sites in China
- Volunteers
- 518 people, healthy volunteers welcome
- Sponsor
- Sinocelltech Ltd.
SARS-CoV Infection
COVID-19 Persistence in Stool
This is a longitudinal study in which participants that have been confirmed by a National Health Service (NHS) swab test as COVID-19 positive will be asked to provide faecal and saliva samples, and complete short health/lifestyle…
- Trial name
- CoPS (NCT04546776)
- Where
- 3 sites in United Kingdom
- Volunteers
- 105 people
- Sponsor
- Quadram Institute Bioscience
Coronavirus, Covid19
Impact of Aerosol Box Use on Healthcare Provider Contamination
Aerosol Generating Medical Procedures (AGMP) are procedures that have the potential to create tiny particles suspended in the air. These particles can contain germs such as viruses.
- Conditions
- Coronavirus, Covid19, COVID-19 Acute Respiratory Distress Syndrome
- Trial name
- NCT04880668
- Testing
- Aerosol Box (Splashguard)
- Where
- 4 sites in United States, Canada
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- KidSIM Simulation Program
SARS-CoV-2 Infection, COVID-19
A Study to Learn About New COVD-19 RNA Vaccine Candidates for New Variants in Healthy Individuals
The purpose of this clinical protocol is to learn about the safety, tolerability, and immunogenicity of new BNT162b2 RNA-based vaccine candidates targeting new variants of SARS-CoV-2 in healthy people.
- Trial name
- NCT05997290
- Testing
- BNT162b2 (Omi XBB.1.5), BNT162b2 (Omi JN.1), BNT162b2 (Omi KP.2)
- Where
- 37 sites in United States
- Volunteers
- 1,051 people, healthy volunteers welcome
- Sponsor
- BioNTech SE
COVID-19
A Longitudinal Study of COVID-19 Sequelae and Immunity
Background: COVID-19 is a disease caused by the SARS-CoV-2 virus. It infects the respiratory tract. Some people who get COVID-19 have only mild symptoms.
- Trial name
- NCT04411147
- Where
- United States
- Volunteers
- 583 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Moral Injury
Assessing the Implementation and Feasibility of the SMART-MR
The objective of the proposed pilot study is to assess the feasibility and implementation of the SMART-MR program, an integration of stress management, general resilience, and moral resilience skills, with frontline staff who…
- Trial name
- NCT05122910
- Testing
- Stress Management and Resilience Training - Moral Resilience (SMART-MR) program
- Where
- Canada
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Healthy
Study to Investigate the Mass Balance, Metabolism, and Excretion of [14C]-PF-07304814 in Healthy Participants
This open-label, single dose study in approximately 5 healthy male and female (of non childbearing potential only) participants has been designed to characterize mass balance and further the understanding of human…
- Trial name
- NCT05050682
- Testing
- PF-07304814
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Pfizer
COVID-19
Clinical Study in the Treatment of Patients With Moderate Course of COVID-19
Study of safety, efficacy and pharmacokinetics, dose selection
- Trial name
- NCT04842435
- Testing
- COVID-globulin
- Where
- 21 sites in Russia
- Volunteers
- 376 people
- Sponsor
- Microgen
COVID-19, Diabete Mellitus
Long-Term Sequelae of SARS-COV-2 Infection: Diabetes Mellitus
Hospitalized patients with severe COVID-19 have an increased incidence of insulin resistance, impaired beta cell function, glucose intolerance (prediabetes), and overt type 2 diabetes (T2D) compared to non-hospitalized patients…
- Trial name
- NCT05867017
- Testing
- Measure of physiologic parameters
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
COVID-19, Corona Virus Infection
A Phase II, Controlled Clinical Study Designed to Evaluate the Effect of ArtemiC in Patients Diagnosed With COVID-19
Agent Name and Study Duration ArtemiC is a medical spray comprised of Artemisinin (6 mg/ml), Curcumin (20 mg/ml), Frankincense (=Boswellia) (15 mg/ml) and vitamin C (60 mg/ml) in micellar formulation for spray administration.
- Conditions
- COVID-19, Corona Virus Infection, SARS-CoV 2, Coronavirus
- Trial name
- NCT04382040
- Testing
- ArtemiC
- Where
- 4 sites in India, Israel
- Volunteers
- 50 people
- Sponsor
- MGC Pharmaceuticals d.o.o
Post Traumatic Stress Disorder, Anxiety
Level and Predictors of Trauma-symptoms Among Health Workers and Public Service Providers During the COVID-19 Outbreak
The aim of this study is to investigate the levels of trauma and mental symptoms (i.e., depression and anxiety) among health workers and public service providers during the strict social distancing government-initiated…
- Conditions
- Post Traumatic Stress Disorder, Anxiety, Depression
- Trial name
- NCT04374097
- Where
- Norway
- Volunteers
- 1,778 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Depression
Assessment of Stress, Depression and Anxiety in Healthcare Caring for Patients With COVID-19
Medical personnel working in the Intensive Care Unit will be examined by means of tests. Their aim is to check how work-related stress in a potentially lethal threat affects the occurrence of depression, stress, anxiety and sleep…
- Trial name
- NCT04631497
- Testing
- test
- Where
- Poland
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Covid19, Sars-CoV-2 Infection
Management of Cytokine Storms in Severe COVID-19 Patients With Autologous Activated Platelet-rich Plasma Therapy
The positive cases of coronavirus disease-2019 (COVID-19) in Indonesia has been increasing rapidly since the first case found in March 2020 to date.
- Conditions
- Covid19, Sars-CoV-2 Infection, ARDS, Human, Severe covid19
- Trial name
- NCT04715360
- Testing
- autologous activated platelet-rich plasma, Avigan
- Where
- Indonesia
- Volunteers
- 30 people
- Sponsor
- Hayandra Peduli Foundation
COVID-19, SARS-CoV 2
Convalescent Plasma for the Treatment of Patients With COVID-19
This expanded access program will provide access to COVID-19 convalescent plasma 150 or more individuals with moderate to severe or life-threatening manifestations of COVID-19, or documented to be at high risk of developing such…
- Trial name
- NCT04372368
- Testing
- COVID-19 Convalescent Plasma
- Where
- 6 sites in United States
- Sponsor
- University of Colorado, Denver
COVID-19
Antibody Responses in Contacts of COVID-19 Patients
After several cases of pneumonia with an unfamiliar etiology were observed at the end of 2019, the National Health Commission of China released more details about the epidemic in early 2020.
- Trial name
- NCT04444310
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Vaccination Refusal
Does the COVID-19 Vaccination Rate Change According to the Education, Income, Culture Level, Prosociality ?
"Does the COVID-19 vaccination rate change according to the education, income, culture level, social mindfulness and prosociality ?"
- Trial name
- NCT05057208
- Testing
- COVID
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
SARS (Severe Acute Respiratory Syndrome)
Colloidal Silver, Treatment of COVID-19
Noble metals such as gold and silver have been appreciated for millennia not only for their beauty but also for their ability to fight diseases.
- Trial name
- NCT04978025
- Testing
- Colloidal Silver
- Where
- Tunisia
- Volunteers
- 50 people
- Sponsor
- Hôpital Universitaire Sahloul
Long COVID
A Cross-sectional, Observational Study to Characterise Long COVID-19 in an Urban Sample of South African Adults
"Long-COVID'' (also known as post-COVID-19 syndrome, post-acute sequelae of COVID-19, or chronic COVID syndrome, used here as 'Long-COVID' for brevity), is a complex array of postconvalescence symptoms following SARS-CoV-2…
- Trial name
- ChaLOC (NCT05445713)
- Where
- 2 sites in South Africa
- Volunteers
- 400 people
- Sponsor
- University of Witwatersrand, South Africa
COVID-19
Validation of Prognostic Clinical Risk Scores in Predicting Outcome for Patients With COVID-19 at Initial Triage
Background Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) causing Covid-19 pandemic continues to be a global health threat with a massive burden on health care systems resulting in more than six million deaths in…
- Trial name
- NCT05582382
- Testing
- logistic regression of known prognostic markers of severity of COVID19
- Where
- United Arab Emirates
- Volunteers
- 2,000 people
- Sponsor
- Dr Adnan Agha
COVID-19 Infection
Clazakizumab vs. Placebo - COVID-19 Infection
The purpose of this study is to investigate the effectiveness and safety of treatment with clazakizumab compared to a placebo (inactive substance).
- Trial name
- NCT04494724
- Testing
- Clazakizumab
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- The Methodist Hospital Research Institute
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