Clinical trials: COVID-19 Vaccine
COVID-19 Vaccine
ARVAC - A New Recombinant Coronavirus Disease 2019 (COVID-19) Vaccine
The objective of this clinical trial is to test a new vaccine against SARS-CoV-2 (ARVAC-CG) in healthy adult volunteers, previously vaccinated against the SARS-CoV-2 virus.
- Trial name
- NCT05656508
- Testing
- ARVAC-CG vaccine (recombinant protein vaccine against SARS-CoV-2)
- Where
- Argentina
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Laboratorio Pablo Cassara S.R.L.
Covid19 Vaccine
A Study to Evaluate Immunogenicity and Safety of MVC-COV1901 Compared With AZD1222 Against COVID-19 in Adults
The purpose of this study is to assess the immunogenicity and safety of MVC-COV1901 vaccine compared to AZD1222 in heathy adults.
- Trial name
- NCT05011526
- Testing
- MVC-COV1901, AZD1222
- Where
- 2 sites in Paraguay
- Volunteers
- 1,030 people, healthy volunteers welcome
- Sponsor
- Medigen Vaccine Biologics Corp.
Covid19
Study of a Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) Virus-like Particle (VLP) Vaccine
This is a randomized, parallel dose assigned, double blind, multi center, Phase II study assessing the efficacy, safety, and immunogenicity of VLP vaccine (Authentic and Alpha variants) in adults between 18 and 59 years who are…
- Trial name
- COVID-19 (NCT04962893)
- Testing
- SARS-CoV-2 VLP Vaccine-Wuhan, SARS-CoV-2 VLP Vaccine-Alpha (British) variant, SARS-CoV-2 VLP Vaccine-Wuhan+Alpha variant
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 349 people, healthy volunteers welcome
- Sponsor
- Ihsan GURSEL, PhD, Prof.
SARS-CoV-2 Infection
A Study of SARS CoV-2 Infection and Potential Transmission in Individuals Immunized With Moderna COVID-19 Vaccine
The purpose of this study is to assess SARS CoV-2 infection, viral shedding, and subsequent potential transmission in individuals immunized with the Moderna COVID-19 vaccine.
- Trial name
- CoVPN 3006 (NCT04811664)
- Testing
- Moderna COVID-19 Vaccine
- Where
- 51 sites in United States
- Volunteers
- 1,923 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Comorbidities and Coexisting Conditions, Healthy
Immune Response of an Interchangeable Booster Vaccine Against COVID-19 Among Individuals With Risk Factors for Severity
Experimental, single-arm study in participants with comorbidities, previously immunized with 2 doses of CoronaVac, who will receive a booster vaccine with 1 dose of the Oxford/AstraZeneca vaccine.
- Trial name
- COVACManaus2 (NCT05289206)
- Testing
- Vaccine - ChAdOx1-S/nCoV-19 [recombinant]
- Where
- Brazil
- Volunteers
- 4,446 people, healthy volunteers welcome
- Sponsor
- Fundação de Medicina Tropical Dr. Heitor Vieira Dourado
COVID-19 Vaccination
A Multicomponent Clinic-based Intervention to Promote COVID-19 Vaccine Intention and Uptake Among Diverse Youth and Adolescents
The goal of this study is to refine and test CONFIDENCE, a multi-component clinic-based intervention in pediatric or family practice clinical settings.
- Trial name
- CONFIDENCE (NCT05722652)
- Testing
- CONFIDENCE
- Where
- United States
- Volunteers
- 667 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
COVID-19
Can Doctors Reduce COVID-19 Misinformation and Increase Vaccine Uptake in Ghana? A Cluster-randomised Controlled Trial
Whilst Ghana was one of the first countries to start vaccinating its population against COVID-19, less than 30% of the population was fully vaccinated at the end of 2022.
- Trial name
- NCT06191211
- Testing
- Motivational Interviewing, AIMS, Facility engagement
- Where
- Ghana
- Volunteers
- 7,000 people, healthy volunteers welcome
- Sponsor
- London School of Economics and Political Science
COVID-19 Vaccines
A Study of COVID-19 Vaccine(s) in Children and Adults
The purpose of this study is to learn about the safety and effects of updated COVID-19 vaccines (called BNT162b2) in participants 5 Through 64 Years of Age with risk factors for Severe COVID-19, and Participants 65 Years of Age…
- Trial name
- NCT07798648
- Testing
- BNT162b2
- Where
- 14 sites in United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- BioNTech SE
COVID-19, SARS-CoV-2 Infection
A Randomized Trial Evaluating a mRNA-VLP Vaccine's Immunogenicity and Safety for COVID-19
The purpose of this study is to characterize the safety and immunogenicity of AZD9838 and AZD6563 when administered as a single dose vaccination against SARS-CoV-2 in adults.
- Trial name
- ARTEMIS-C (NCT06147063)
- Testing
- AZD9838, Licensed SARS-CoV-2 mRNA vaccine, AZD6563
- Where
- 5 sites in United States
- Volunteers
- 243 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
SARS-CoV2, Covid19
A Study on the Safety, Tolerability and Immune Response of SARS-CoV-2 Sclamp (COVID-19) Vaccine in Healthy Adults
This study is being conducted to look at the safety and immune response (how the immune system of the human body reacts) to a vaccine for SARS-CoV-2 (the virus responsible for COVID-19 infection) when administered as an…
- Trial name
- NCT04495933
- Testing
- MF59 adjuvanted SARS-CoV-2 Sclamp vaccine 5mcg, MF59 adjuvanted SARS-CoV-2 Sclamp vaccine 15mcg, MF59 adjuvanted SARS-CoV-2 Sclamp vaccine 45mcg
- Where
- Australia
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- The University of Queensland
Vaccine Adverse Reaction
Expectations About the COVID-19 Vaccines
This study collects information on expectations and attitudes towards the COVID-19 vaccines in participants about to receive a COVID-19 vaccine.
- Trial name
- NCT04928911
- Testing
- COVID-19 vaccine
- Where
- Denmark
- Volunteers
- 1,176 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Multiple Myeloma
COVID19 OutcomeS in Myeloma and the Impact of VaCcines
The COVID-19 pandemic has had an outsized impact on individuals with underlying social and medical vulnerability, leading to increased rates of severe disease, hospitalization, and death in these groups.
- Trial name
- COSMIC (NCT05831787)
- Testing
- Patient Reported Outcomes
- Where
- 2 sites in United States
- Volunteers
- 201 people
- Sponsor
- ASH Research Collaborative
COVID-19 Infection, COVID-19 Vaccine
To Explore the Protective Effect of SARS-CoV-2 Vaccination on Cancer Patients Infected With SARS-CoV-2
For tumor patients, the virus antibody titer produced by the SARS-CoV-2 vaccine is often lower than that of normal people in a short period of time, but in the long run, it can significantly reduce the infection rate and fatality…
- Trial name
- NCT05774171
- Testing
- no intervention
- Where
- China
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
COVID-19 Vaccines
Comparative Evaluation of Covid-19 Vaccines Response
Study Population Population with vaccinated with three different Covid Vaccines (Inactive Vaccine (Sinovac Life Sciences, Beijing, China), recombinant human adenovirus serotype number 26 (rAd26 of Sputnik V), mRNA Vaccine…
- Trial name
- NCT04895007
- Testing
- Covid-19 Inactive Vaccine, recombinant human adenovirus serotype number 26, mRNA VAccine
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Karamanoğlu Mehmetbey University
SARS-CoV Infection
National Cohort Study of Effectiveness and Safety of SARS-CoV-2/COVID-19 Vaccines (ENFORCE)
National cohort study of effectiveness and safety of SARS-CoV-2 vaccines (ENFORCE is an equivalence trial to evaluate the effectiveness and safety of multiple new SARS-CoV-2 vaccines approved for use in the EU, and which are…
- Trial name
- ENFORCE (NCT04760132)
- Testing
- COMIRNATY - BioNTech Manufacturing GmbH, COVID-19 Vaccine Moderna dispersion for injection - MODERNA BIOTECH, COVID-19 Vaccine AstraZeneca suspension for injection
- Where
- 5 sites in Denmark
- Volunteers
- 7,600 people, healthy volunteers welcome
- Sponsor
- Jens D Lundgren, MD
Hematologic Disorders and Bone Marrow Failure, Hematopoietic Stem Cell Transplantation (HSCT) or Cellular Therapy (CART)
Response to SARS-CoV-2 Vaccine in Stem Cell Transplant and Cellular Therapy Patients
For many patients with hematologic disorders and bone marrow failure, hematopoietic stem cell transplantation (HSCT) or cellular therapy (CART) offers a curative treatment option.
- Trial name
- NCT04723706
- Testing
- COVID-19 serology IgG
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Henry Ford Health System
COVID-19
Evaluation of Corfluvec Vaccine for the Prevention of COVID-19 in Healthy Volunteers
The aim of the study is to investigate the safety and immunogenicity of a two-component intranasal vaccine for the prevention of COVID-19 in healthy volunteers 18-60 years old
- Trial name
- NCT05696067
- Testing
- Corfluvec component 1 low dose, Corfluvec component 2 low dose, Corfluvec component 1 high dose
- Where
- 2 sites in Russia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tatyana Zubkova
Health Equity, COVID-19
Public Support for COVID-19 Test Allocation
In a randomized survey experiment, investigators will assess public support or opposition towards one of three potential government plans for allocating at-home coronavirus disease 2019 (COVID-19) tests to United States…
- Trial name
- NCT05185687
- Testing
- First Come, First Served, Random, Disadvantaged Priority & Random
- Where
- United States
- Volunteers
- 2,019 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Metabolic Associated Fatty Liver Disease
Clinical Study of SARS-CoV-2 Vaccine in Metabolism-related Fatty Liver Disease
The coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 causes high morbidity and mortality worldwide. SARS-CoV-2 vaccination is currently the most effective means of reducing morbidity, severe illness and mortality risk.
- Trial name
- NCT05738707
- Testing
- Recombinant protein vaccine and adenovirus vector vaccine
- Volunteers
- 100 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Myocardial Injury, Vaccine Adverse Reaction
Myocardial Injury After BNT162b2 mRNA COVID-19 Fourth Dose Vaccination Among Israeli Health Care Workers
The aim of the study is to prospectively evaluate the incidence of myocardial injury after the administration of the fourth dose BNT162b2 mRNA vaccine (Pfizer-BioNTech) against COVID-19.
- Conditions
- Myocardial Injury, Vaccine Adverse Reaction, COVID-19
- Trial name
- NCT05308680
- Testing
- BNT162b2
- Where
- Israel
- Volunteers
- 336 people, healthy volunteers welcome
- Sponsor
- Shaare Zedek Medical Center
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