Clinical trials: COVID-19 Virus Infection
SARS-CoV 2
Lung Irradiation for COVID-19 Pneumonia
In this research study the investigators want to learn more about the potential benefit of radiation to the lung to improve the health of patients who are hospitalized with Coronavirus-19 (COVID-19) due to infection with a virus…
- Trial name
- NCT04393948
- Testing
- Phase 1, Phase 2
- Where
- United States
- Sponsor
- Brigham and Women's Hospital
SARS-CoV-2
Seroprevalence of Coronavirus Disease 2019 (COVID-19) Antibodies in a Vulnerable Neighbourhood, Buenos Aries Argentina
Background The study aimed to establish the seroprevalence of SARS-COV-2 in an Argentinian slum three months after the first case was reported.
- Trial name
- NCT04472078
- Testing
- Serological Assay or IgG for SARS-CoV-2
- Where
- Argentina
- Volunteers
- 873 people
- Sponsor
- Hospital Italiano de Buenos Aires
COVID-19
Analysis of Suicide Dynamics in Link to the COVID-19 Pandemic
Covid is a virus that first appeared in China in 2019 and was quickly described as a pandemic virus by its globalized nature. The unprecedented occurrence of the virus has led to several health and restrictive government…
- Trial name
- DSL-Covid-19 (NCT06084143)
- Where
- France
- Volunteers
- 2,500 people
- Sponsor
- University Hospital, Strasbourg, France
Sepsis, Blood Coagulation Disorders
Analysis of the Coagulopathy Developed by COVID-19 Infected Patients
Increased D-dimers at admission of COVID-19 infected patients entering hospital due to a severe disease is a risk factor for death.
- Conditions
- Sepsis, Blood Coagulation Disorders, Thrombin, Disseminated Intravascular Coagulation
- Trial name
- COVID-TGT (NCT04356950)
- Testing
- Thrombin generation test assay, Fibrin generation markers assays
- Where
- 4 sites in France
- Volunteers
- 175 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Hypertension
Personalised Electronic Record Supported Optimisation When Alone for Patients With Hypertension
This trial is focusing on blood pressure control for patients with high blood pressure (hypertension) during the COVID-19 pandemic when seeing a doctor for advice may be difficult.
- Trial name
- PERSONALCovdBP (NCT04559074)
- Testing
- Amlodipine
- Where
- 2 sites in United Kingdom
- Volunteers
- 343 people
- Sponsor
- Queen Mary University of London
Long COVID
Mental Intervention and Nicotinamide Riboside Supplementation in Long Covid
Long COVID, also referred to as post-acute sequela of COVID-19 (PASC), is present in a substantial number of individuals, and treatment for this is warranted.
- Trial name
- MINIRICO (NCT05703074)
- Testing
- Nicotinamide Riboside (NR), Mind-body reprocessing therapy (MBRT), Care as usual
- Where
- Norway
- Volunteers
- 310 people
- Sponsor
- University Hospital, Akershus
COVID-19
Engaging Staff to Improve COVID-19 Vaccination Response at Long-Term Care Facilities
The ENSPIRE study is a cluster-randomized comparative effectiveness trial being conducted within long-term care and residential facilities that will test a communication and engagement strategy for increasing COVID-19 booster…
- Trial name
- ENSPIRE (NCT05449418)
- Testing
- Full Intervention, Enhanced Usual Care
- Where
- 2 sites in United States
- Volunteers
- 988 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Long COVID, Post-Acute Sequelae of COVID-19
Mind Body Intervention for Long COVID-19
The goal of this study is to determine if a mind-body intervention can help people suffering from symptoms associated with Long COVID.
- Conditions
- Long COVID, Post-Acute Sequelae of COVID-19, COVID Long-Haul
- Trial name
- NCT06045338
- Testing
- Mind Body Intervention #1
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Beth Israel Deaconess Medical Center
COVID-19, Influenza A
Clinical Evaluation of the Panbio™ COVID-19/Flu A&B Panel
The study is designed as a prospective, multicentric, clinical study to investigate the positive percent agreement (PPA) and negative percent agreement (NPA) of the Panbio™ COVID-19/Flu A\&B Panel using anterior nasal swab…
- Conditions
- COVID-19, Influenza A, Influenza B
- Trial name
- NCT06127108
- Testing
- Panbio™
- Where
- United States
- Volunteers
- 447 people
- Sponsor
- Abbott Rapid Dx
COVID-19, Mental Health Disorder
Treatment of Post-covid Syndrome in Patients Treated in Intensive Care
The present study is a pilot randomized controlled trial, which identifies and diagnoses mental health problems in survivors of critical COVID-19 infection at 12 months post-ICU care, and randomize patients to either an…
- Trial name
- NCT05119608
- Testing
- CBT/ACT
- Where
- 2 sites in Sweden
- Volunteers
- 40 people
- Sponsor
- Region Skane
COVID-19
Community Perception on COVID-19 Prevention and Control
In times whereby COVID-19 is rapidly spreading, research on the epidemiological, diagnostic, clinical and social aspects of the illness has been highlighted as important as there is very limited information of this disease in all…
- Trial name
- NCT06452108
- Where
- Pakistan
- Volunteers
- 2,651 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
COVID-19 SARS-CoV-2 Infection
A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease
The purpose of the study is to evaluate whether ibuzatrelvir is effective and safe in adults and adolescents with COVID-19 who do not need to be in the hospital but who are at high risk for progression to severe disease.
- Trial name
- NCT06679140
- Testing
- ibuzatrelvir
- Where
- 256 sites in United States, Argentina and 17 more
- Volunteers
- 2,330 people
- Sponsor
- Pfizer
COVID-19 Infection
Extension Study in a Cohort of Adult Patients With COVID-19 Infection
The main objective of this study is to evaluate the incidence of post-COVID morbidity and characterize the complications profile in patients who participated in the APLICOV-PC study.
- Trial name
- E-APLICOV-PC (NCT05121740)
- Testing
- Plitidepsin 1.5 mg / day, Plitidepsin 2.0 mg / day, Plitidepsin 2.5 mg / day
- Where
- 10 sites in Spain
- Volunteers
- 34 people
- Sponsor
- PharmaMar
Primary Immune Deficiency, COVID
COVID-19 in PID Survey
With the emergence of SARS-CoV-2 and the COVID-19 pandemic, there is an urgent need to understand the impact of infection on immunodeficient individuals.
- Trial name
- COPID19 (NCT04459689)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Imagine Institute
Mechanical Ventilation, Usual Care
Global BurdEn of MechanIcal VeNtilatIon (GEMINI). VeNtilatIon (GEMINI Study) 2022 for VENTILAGROUP.
BACKGROUND: Changes in the clinical practice of mechanical ventilation during and after the coronavirus pandemic (COVID-19) worldwide could influence the clinical outcomes of critically ill patients with mechanical ventilation…
- Conditions
- Mechanical Ventilation, Usual Care, Noninvasive Positive Pressure Ventilation, High Flow Oxygen Therapy
- Trial name
- GEMINI (NCT05392010)
- Testing
- no intervention
- Where
- Spain
- Volunteers
- 10,900 people
- Sponsor
- Hospital Universitario Getafe
Prevention of Infection Disease Caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2)
A Study of TAK-019 in Healthy Japanese Adults (COVID-19)
TAK-019 is a vaccine in development to protect people against Covid-19. The main aims of the study are to learn if TAK-019 can protect people from Covid-19 and to check for side effects from TAK-019.
- Trial name
- NCT04712110
- Testing
- TAK-019
- Where
- 2 sites in Japan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Takeda
Solid Organ Transplant Rejection, COVID-19
AlloSure Guided Immuno-Optimization for COVID-19: An Early Experience
The utilization of AlloSure to help guide immunosuppression management in solid organ transplant recipients diagnosed with COVID-19
- Trial name
- Al-COVE (NCT04341103)
- Volunteers
- 500 people
- Sponsor
- CareDx
Depression
Testing Scalable, Single-Session Interventions for Adolescent Depression in the Context of COVID-19
Most mental health problems emerge by age 14, often leading to chronic impairments and adverse impacts for individuals, families, and societies.
- Trial name
- NCT04634903
- Testing
- Supportive Therapy SSI, Behavioral Activation SSI, Growth Mindset SSI
- Where
- United States
- Volunteers
- 2,452 people
- Sponsor
- Stony Brook University
Abdominal Cancer, Thoracic Cancer
Teleprehabilitation for Surgical Cancer Patients
There is a general concern that the backlog of cancer patients waiting for surgery during this period is going to increase and the general impact on patients isolated in their homes is going to cause potential physiological and…
- Trial name
- NCT04799561
- Testing
- Multimodal Teleprehabilitation
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Covid19, Fertility Issues
Prospective Two-arm Study of Fertility in Men With COVID-19
COVID-19 infection is hypothesized to have a potentially negative effect on male fertility through direct damage to the testes. The current trial is aimed at investigating the effect of SARS-CoV-2 on fertility and determining if…
- Trial name
- NCT04716179
- Testing
- Sperm test, hormone levels (testosterone, FSH, LH, prolactin), SARS-CoV-2 Ig G levels
- Where
- Russia
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University
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