Clinical trials: CP
Spastic Cerebral Palsy
Feasibility Nutritional Supplements for Muscle Growth in CP
The purpose of this study is to investigate the feasibility of a 10-week plan with a nutritional supplement (leucine) and to perform pilot analyses on the effect of leucine on macroscopic muscle morphology in children with…
- Trial name
- Nut-CP (NCT06044168)
- Testing
- Dietary Supplement: Leucine
- Where
- Belgium
- Volunteers
- 5 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Knee Arthroscopy
Estimation of Effective Dose 95 (ED95) of Intrathecal Isobaric 2-chloroprocaine (2-CP) Based on the Height (cm) of a Patient Undergoing Ambulatory Knee Arthroscopy
In ambulatory surgery, the choice of the local anesthetic used is essential. The ideal local anesthetic must allow a quick installation of the spinal block, a duration of the sensory block adapted to the surgery with a minimum of…
- Trial name
- NCT03882489
- Testing
- Isobaric 2-chloroprocaine
- Where
- Belgium
- Volunteers
- 120 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Quadriplegic Cerebral Palsy, Cerebral Palsy (CP)
Intensive Bimanual Therapy Versus Conventional Physical Therapy in Quadriplegic Cerebral Palsy
Quadriplegic cerebral palsy (CP) is a severe neurological condition affecting motor control in all four limbs, often resulting in profound functional limitations in daily activities.
- Trial name
- NCT07134894
- Testing
- Intensive Bimanual Therapy plus Conventional Physical Therapy, Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- University of Lahore
Cerebral Palsy
Effect of HABIT-ILE on Visuo-spatial Attention of Children With Unilateral CP
This study aims to investigate the changes induced by HABIT-ILE in impairments, activity and participation of children with unilateral CP, as well as neuroplastic changes induced by the treatment.
- Trial name
- HABIT-ILE_CP (NCT02946086)
- Testing
- HABIT-ILE with prismatic adaptation, HABIT-ILE without prismatic adaptation
- Where
- Belgium
- Volunteers
- 35 people
- Sponsor
- Université Catholique de Louvain
Cerebral Palsy
HMB Cerebral Palsy Pilot Study
This is a pilot study of β-hydroxy-β-methylbutyrate (HMB) + Vitamin D3 supplementation in adolescents with cerebral palsy. The primary objective is to quantify safety, compliance, and acceptability of daily combined HMB + Vitamin…
- Trial name
- NCT05384951
- Testing
- HMB + Vitamin D3
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Gillette Children's Specialty Healthcare
Cerebral Palsy, Spastic Diplegia Cerebral Palsy
FES to Improve Gait in CP
The goal of this proposal is to mitigate the typical decline in walking function experienced by children with cerebral palsy (CP) via a Functional Electrical Stimulation (FES)-assisted treadmill training intervention.
- Conditions
- Cerebral Palsy, Spastic Diplegia Cerebral Palsy, Gait
- Trial name
- CP FES Walking (NCT04591288)
- Testing
- Functional Electrical Stimulation protocol, Treadmill only protocol
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- Shriners Hospitals for Children
Chronic Prostatitis (CP), Chronic Prostatitis With Chronic Pelvic Pain Syndrome
Bovine Colostrum Efficacy for the Treatment of Chronic Prostatitis Symptoms.
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a bothering condition characterized by pain localized to the pelvic, perineal and/or genital area and lower urinary tract symptoms (LUTS).
- Conditions
- Chronic Prostatitis (CP), Chronic Prostatitis With Chronic Pelvic Pain Syndrome, Chronic Prostatitis/ Pelvic Pain Syndrome
- Trial name
- NCT06804083
- Testing
- oral combination of colostrum and Serenoa repens extracts (PROSTYM®)
- Where
- Italy
- Volunteers
- 42 people
- Sponsor
- Clinica Urologica Molinette - Città della Saliute e della Scienza
Diplegic Cerebral Palsy With Spasticity, Cerebral Palsy, Spastic, Diplegic
Impact of rTMS Combined With Neurorehabilitation on Lower Extremity Motor Function and Spasticity in Children With Spastic Diplegic Cerebral Palsy
Cerebral palsy (CP) is widely recognized as the most prevalent cause of lifelong physical disability emerging in childhood across most global populations.
- Conditions
- Diplegic Cerebral Palsy With Spasticity, Cerebral Palsy, Spastic, Diplegic, Transcranial Magnetic Stimilation, Cerebral Palsy (CP)
- Trial name
- NCT07488429
- Testing
- TMS
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Ankara City Hospital Bilkent
Cerebral Palsy (CP)
Comparative Effects of Frenkel's and Core Stability Exercises in Children With Cerebral Palsy
The aim of this study is to determine and compare the effects of Frenkel's and core stability exercises on the motor function, postural stability and core muscle strength in children with cerebral palsy.
- Trial name
- NCT06696989
- Testing
- Frenkel's exercises, Core stability exercises
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Riphah International University
Cerebral Palsy (CP)
Clinical Improvement Due to the Home Use of Agilik in Children With Cerebral Palsy
The goal of this clinical trial is to learn if a two month training with the Agilik powered orthosis improves the knee extension or the endurance in pediatric patients with Cerebral palsy and a crouch gait.
- Trial name
- Agilik@home (NCT06622655)
- Testing
- Powered orthosis
- Where
- 6 sites in Italy
- Volunteers
- 40 people
- Sponsor
- IRCCS Eugenio Medea
Cardiovascular Diseases, Diabetes Mellitus
A Community Paramedicine Initiative for Older Adults Living in Subsidized Housing (CHAP-EMS/CP@Clinic)
Older adults living in subsidized housing report poorer health. Their age and low income make it harder for them to use community services.
- Trial name
- CHAP-EMS (NCT02152891)
- Testing
- CHAP-EMS/CP@clinic
- Where
- 5 sites in Canada
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- McMaster University
Cerebral Palsy
CP-EDIT: Cerebral Palsy - Early Diagnosis and Intervention Trial
Background. Early diagnosis of cerebral palsy is important as intervention becomes possible at a time where neuroplasticity is at the highest. Current mean age at diagnosis is 13 months in Denmark.
- Trial name
- CP-EDIT (NCT05835674)
- Testing
- Early intervention program
- Where
- 4 sites in Denmark
- Volunteers
- 500 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cerebral Palsy (CP)
Core Stability Exercises vs Hippotherapy for Spastic Cerebral Palsy
Cerebral palsy is associated with impaired balance and trunk control, which affect functional mobility and independence. This randomized clinical trial compares the effects of core stability exercises versus hippotherapy, both…
- Trial name
- NCT07851701
- Testing
- core stability exercises, hippotherapy
- Where
- Pakistan
- Volunteers
- 49 people
- Sponsor
- Riphah International University
Cerebral Palsy, Exercise
A Feasibility Randomised Controlled Trial of an Online Exercise Programme for Adults With Cerebral Palsy
Adults with cerebral palsy (CP) often face challenges in accessing exercise programmes that are appropriate for their needs. Barriers such as limited mobility, a lack of tailored options, and restricted access to physiotherapy…
- Conditions
- Cerebral Palsy, Exercise, Adults, Fitness
- Trial name
- NCT06983782
- Testing
- Exercise and education programme, control group
- Where
- Ireland
- Volunteers
- 47 people
- Sponsor
- Royal College of Surgeons, Ireland
Leukemia
Nilotinib in Treating Patients With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia
RATIONALE: Nilotinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. PURPOSE: This phase II trial is studying how well nilotinib works in treating patients with newly diagnosed chronic…
- Trial name
- NCT00809211
- Testing
- nilotinib, cytogenetic analysis, mutation analysis
- Where
- 6 sites in United States, Germany and 2 more
- Volunteers
- 40 people
- Sponsor
- Cancer Trials Ireland
Cerebral Palsy
Allogeneic UCB Therapy With EPO in Children With CP
This randomized controlled study aims to evaluate the efficacy and safety of allogeneic umbilical cord blood therapy combined with erythropoietin for children with cerebral palsy.
- Trial name
- NCT01991145
- Testing
- Umbilical Cord Blood therapy, Erythropoietin alfa, Rehabilitation
- Where
- South Korea
- Volunteers
- 92 people
- Sponsor
- MinYoung Kim, MD, PhD
Cerebral Palsy (CP)
Virtual Hand-Arm Assessments for Children With Cerebral Palsy
Cerebral palsy (CP) affects approximately 1 in 500 Canadian children, and the majority experience hand and arm limitations that impact independence, participation in daily activities, and overall quality of life.
- Trial name
- NCT07383753
- Testing
- Upper-Limb Virtual and In-Person Assessment
- Where
- 3 sites in Canada
- Volunteers
- 100 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Chronic Pancreatitis
Effect of CREON on Exocrine Pancreatic Insufficiency (EPI) Symptoms
Exocrine Pancreatic Insufficiency (EPI) is a condition where pancreatic enzyme quantity or activity is reduced below threshold needed for normal digestion. Symptoms include bloating, flatulence, diarrhea and steatorrhea.
- Trial name
- CisCP (NCT04949828)
- Testing
- CREON
- Where
- 6 sites in United States
- Volunteers
- 63 people
- Sponsor
- AbbVie
Spastic Cerebral Palsy (sCP)
Stop Tip-toeing Around Toe-walking
The purpose of this study is to explore the interplay among nervous-, musculoskeletal-, and psychological systems and how they impact toe-walking behavior, and vice versa.
- Trial name
- NCT04879199
- Testing
- Static stability measurement, Dynamic stability measurement
- Where
- Switzerland
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital Basel
Executive Functions in Cerebral Palsy
Personalized Innovative Intervention Pathways to Promote EF in Children With CP
Cerebral palsy (CP) is an umbrella term, covering a group of disorders of movement and posture. It is now accepted that CP represents much more than a disorder of movements considering the frequent association with a broad range…
- Trial name
- NCT06288971
- Testing
- Self-adaption web-based software for the rehabilitation of EF and visuo-spatial abilities, Tele-rehabilitation of EF and specific cognitive processes underlying academic skills, Game-based tools for the rehabilitation of EF and motor planning
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- IRCCS Fondazione Stella Maris