Clinical trials: CRP
Hypertension, Periodontitis
Interaction Between Hypertension and Periodontitis
Objective:The possible association between hypertension and periodontitis and the effect of hypertension on periodontal treatment were investigated by evaluating salivary and gingival crevicular fluid (GCF) interleukin (IL)-6 and…
- Trial name
- NCT05741970
- Testing
- Scaling and root planing
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Gazi University
Abortion Early
The Relation of High Sensitivity C Reactive Protein and Total Leucocytic Count Levels in Threatened Abortion
to identify the relation between maternal serum high sensitivity C reactive protein and total and differential leucocytic count values in healthy pregnant women with threatened abortion and the outcome of pregnancy
- Trial name
- NCT05986357
- Testing
- maternal serum C reactive protein, total leucocytic count levels, differential leucocytic count levels
- Where
- Egypt
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
HIV
Attenuation of D-dimer Using Vorapaxar to Target Inflammatory and Coagulation Endpoints
ADVICE is a randomised, international, double-blind, placebo-controlled trial. The purpose of the ADVICE study is to compare the safety and efficacy of vorapaxar in reducing d-dimer expression and markers of cellular immune…
- Trial name
- ADVICE (NCT02394730)
- Testing
- vorapaxar
- Where
- 7 sites in United States, Australia
- Volunteers
- 65 people
- Sponsor
- Kirby Institute
Healthy, Dietary Habits
A Culture-tailored Plant-based Dietary Intervention in Taiwan
The goal of this pilot randomized crossover feasibility trial is to determine the feasibility of a short-term, culture-tailored, plant-based dietary behavior intervention and examine the preliminary outcomes regarding…
- Trial name
- NCT07728877
- Testing
- Plant-Based Diet, General Diet
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tzu Chi University
Healthy Volunteers, C-Reactive Protein
A Study of LY5625575 in Healthy Participants and in Participants With Inflammation (Elevated C-Reactive Protein)
The main purpose of this study is to evaluate the safety and tolerability of LY5625575 in healthy participants (including Japanese and Chinese) and in participants with high levels of a marker for inflammation (C-reactive…
- Trial name
- NCT07801300
- Testing
- LY5625575
- Where
- 2 sites in United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Postoperative Hematoma
Postoperative CRP Levels and Vaginal Cuff Hematoma
After laparoscopic hysterectomy, authors aimed to determine cuff hematoma and a postoperative CRP value to help predict the other complications.
- Trial name
- NCT03879499
- Volunteers
- 106 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Antioxidants, Oxidative Stress
The Influence of Melatonin Supplementation in the Group of Persons Performing Competitive Sport.
The research aims to determine the impact of 30-day supplementation of melatonin on the antioxidative defense mechanisms and the release of markers of oxidative stress and inflammation in rowers and footballers undergoing…
- Conditions
- Antioxidants, Oxidative Stress, Inflammation, Lipid Peroxidation
- Trial name
- NCT03505411
- Testing
- melatonin supplementation
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Nicolaus Copernicus University
Acute Respiratory Tract Infections
FebriDx DISRUPT Acute Respiratory Infection Trial in Acute Respiratory Infection: An Evaluation of FebriDx® POC Test
The aim of this study is to determine performance characteristics of the FebriDx test in predicting viral or bacterial infection etiology among febrile (observed or reported) patients presenting the emergency department, urgent…
- Trial name
- NCT02018198
- Testing
- FebriDx
- Where
- 20 sites in United States
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- Rapid Pathogen Screening
High-sensitivity C-reactive Protein, Carotid Stiffness
High-Sensitive CRP and Carotid Stiffness Between Patients With and Without Coronary Slow Flow
This study aims to compare the levels of high-sensitivity C-reactive protein (hs-CRP) and carotid artery stiffness between patients with coronary slow flow phenomenon (CSFP) and those with normal coronary flow.
- Conditions
- High-sensitivity C-reactive Protein, Carotid Stiffness, Coronary Slow Flow
- Trial name
- NCT07076745
- Testing
- High-sensitivity C-reactive protein, Stiffness Measurement
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University
Periodontal Inflammation
Saliva Levels of S100A12, CRP, Fetuin-A in Periodontal Disease Patients
Hs-CRP, Fetuin-A and S100A12 are acute phase proteins associated with many systemic diseases and conditions. The aim of this study was to determine the clinical parameters and salivary Hs-CRP, Fetuin-A and S100A12 levels before…
- Trial name
- NCT03345745
- Testing
- salivary samples
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Ordu University
Periodontal Diseases Inflammation, Periodontal Disease
Timing of Oral Hygiene Improvement Relative to Subgingival Instrumentation
This single-centre, randomized split-mouth trial assessed clinical periodontal changes and acute systemic inflammatory responses when supra- and subgingival instrumentation was performed concurrently with oral hygiene instruction…
- Conditions
- Periodontal Diseases Inflammation, Periodontal Disease, Periodontal Attachment Loss, Periodontal Pocket
- Trial name
- NCT07914400
- Testing
- Nonsurgical periodontal treatment
- Where
- Slovenia
- Volunteers
- 10 people
- Sponsor
- University of Ljubljana
Coronary Artery Disease
Alternative Risk Markers in Coronary Artery Disease (ARMCAD)
Estimating the risk of future cardiovascular events such as death, stroke and myocardial infarction using traditional risk factors (such as age, gender, smoking, diabetes, hyperlipidaemia and hypertension) is well accepted in…
- Trial name
- NCT00403351
- Where
- 4 sites in Australia
- Volunteers
- 665 people
- Sponsor
- Monash University
Immune Response
LIFEHOUSE: Description of the Tent Bucket -Immune Support
This immune support program will be an extension to the existing LIFEHOUSE program. Essential employees in Gig Harbor, WA; Colonial Heights, VA; Lenexa, KS, and Santa Fe Springs, CA, will be offered complimentary supplementation…
- Trial name
- LIFEHOUSE (NCT04734288)
- Testing
- Vit.D3 5000 IU, Immune Active
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Metagenics, Inc.
Metabolic Syndrome, Overweight
Systematic Review and Meta-analysis of the Differential Effects of DHA and EPA on Inflammation
According to the World Health Organization, cardiovascular diseases (CVDs) are the number 1 cause of death globally. Systemic and local tissue inflammation is now recognized as a key etiological process leading to CVD.
- Conditions
- Metabolic Syndrome, Overweight, Obesity, Chronic Inflammation
- Trial name
- NCT03520556
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Laval University
Febrile Neutropenia (FN), Pediatric Cancer
Early Discontinuation of Antibiotics in Paediatric High-risk Febrile Neutropenia
The goal of this clinical trial is to evaluate whether stopping antibiotic treatment early is safe in paediatric patients with cancer who develop high-risk febrile neutropenia but show good clinical evolution and low biomarker…
- Conditions
- Febrile Neutropenia (FN), Pediatric Cancer, Hematologic Malignancies, Solid Tumors
- Trial name
- E-STOP2 (NCT07590648)
- Testing
- Early Discontinuation of Antibiotics, Standard Antibiotic Continuation Strategy
- Where
- 4 sites in Spain
- Volunteers
- 136 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Procalcitonin, Infection
Procalcitonin as a Prognostic Predictor in Patients With Acute Infectious Disease Hospitalized in the Internal Medicine Department.
Procalcitonin is a well-known biomarker used to distinguish between bacterial and viral infections, assess a patient's risk category, and serve as a prognostic indicator.
- Conditions
- Procalcitonin, Infection, Internal Medicine Patients
- Trial name
- NCT07770334
- Testing
- No Interventions
- Volunteers
- 1,000 people
- Sponsor
- Barzilai Medical Center
Acute Coronary Syndrome
GALNT4 in Patients With Acute Coronary Syndrome
The expression of GALNT4 in blood with acute coronary syndrome
- Trial name
- NCT03335514
- Testing
- expression of GALNT4
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital of Dalian Medical University
Postoperative Complications
the PRECious Trial: PREdiction of Complications
20% of patients who undergo major abdominal surgery will have a major complication, which requires invasive treatment and is associated with increased mortality, morbidity, hospital stay and intensive care stay.
- Trial name
- PRECious (NCT02102217)
- Testing
- PRECious
- Where
- Netherlands
- Volunteers
- 525 people
- Sponsor
- Amsterdam UMC, location VUmc
Acute Exacerbation of COPD, Lung Diseases
Antibiotic Stewardship in AECOPD Through CRP-Guided Management
Objectives: To determine whether CRP-guided antibiotic treatment for managing AECOPD in adult patients attending Emergency Departments leads to reduced antibiotic duration, without non-inferior COPD health status with usual care.
- Conditions
- Acute Exacerbation of COPD, Lung Diseases, Lung Diseases, Obstructive, Pulmonary Disease, Chronic Obstructive
- Trial name
- NCT05286918
- Testing
- The intervention (CRP-guided) group
- Where
- Hong Kong
- Volunteers
- 1,184 people
- Sponsor
- The University of Hong Kong
Coronary Artery Calcification
Association Between Non-alcoholic Fatty Liver Disease (NAFLD) and Coronary Artery Calcification
Coronary artery disease are 8 times more prevalent in patients with NAFLD then the general population and are being considered the most common cause of death.
- Trial name
- NCT01158066
- Testing
- CT Cardiac
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Ziv Hospital