Clinical trials: CRP
Vitamin D Deficiency
Effect of Vitamin D Supplementation on Health of Low Birth Weight Infants
The purpose of this study is to determine whether a weekly supplement of vitamin D to low birth weight term infants will reduce their mortality and hospital admissions and improve their immunity.
- Trial name
- DIVIDS (NCT00415402)
- Testing
- Vitamin D3
- Where
- India
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Delhi University
Low Back Pain
Radiographic and Inflammatory Biomarker Changes in Chronic Low Back Pain
OBJECTIVE: To find and compare the effects of isokinetic training and virtual reality training on pain intensity, trunk muscle strength, radiographical (muscle cross-sectional area and muscle thickness), and biochemical effects…
- Trial name
- NCT05253599
- Testing
- Isokinetic training, Virtual reality training, Exercises
- Where
- Saudi Arabia
- Volunteers
- 60 people
- Sponsor
- Prince Sattam Bin Abdulaziz University
Cardiovascular Diseases, Atheroma
Periodontal Therapy in Coronary Artery Patients
Gingival inflammation has been associated with cardiovascular diseases, including heart attack and stroke, because of elevation of blood risk markers such as cholesterol, glucose and C reactive protein.
- Conditions
- Cardiovascular Diseases, Atheroma, Coronary Artery Disease
- Trial name
- PerioCardio (NCT01609725)
- Testing
- Subgingival scaling and root planing, Oral prophylaxis
- Where
- Brazil
- Volunteers
- 93 people
- Sponsor
- Federal University of Rio Grande do Sul
Hypertension, Dyslipidemias
Exploring the Effects of Antihypertensive and Lipid-Lowering Drugs on Inflammatory Cytokine Levels
This study investigates the causal relationships between antihypertensive and lipid-lowering drugs and inflammatory cytokines using a drug-targeted Mendelian randomization approach.
- Conditions
- Hypertension, Dyslipidemias, Inflammatory Response, Chronic Inflammation
- Trial name
- MRDLT (NCT06622304)
- Where
- China
- Volunteers
- 250,736 people
- Sponsor
- Guangzhou Institute of Respiratory Disease
Appendicitis
Diagnostic Performance of C Reactive Protein and Delta CRP in Acute Appendicitis
The diagnosis of acute appendicitis is difficult and despite important advances in medical sciences, detailed patient questioning and precise medical examination are the main keystones of the diagnosis of acute appendicitis and…
- Trial name
- dCRPappend (NCT02730585)
- Testing
- C-reactive protein measurement
- Where
- Tunisia
- Volunteers
- 500 people
- Sponsor
- University of Monastir
Acute Aortic Dissection, Surgery (Cardiac)
Immune-Inflammatory Markers in Aortic Dissection
Identifying early on which patients with acute aortic dissection require closer monitoring may help with care planning. If simple, inexpensive values obtained from routine blood tests can provide additional information for…
- Conditions
- Acute Aortic Dissection, Surgery (Cardiac), Systemic Immune-inflammation Index, Postoperative Death
- Trial name
- NCT07683260
- Where
- Turkey (Türkiye)
- Volunteers
- 127 people
- Sponsor
- Bursa City Hospital
Prehypertension, Blood Pressure
The Effects of a Jump Rope Exercise Program on Vascular Health, Inflammatory Markers in Prehypertensive Adolescent Girls
The purpose of this study was to examine the impact of a 12-week jump rope exercise program on blood pressure, arterial stiffness, vasodilating and vasoconstricting factors, inflammatory markers, and body composition in…
- Conditions
- Prehypertension, Blood Pressure, Abdominal Obesity, Adiposity
- Trial name
- NCT03534427
- Testing
- Jump rope exercise intervention
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Pusan National University
Inflammation Biomarkers, Poly Cystic Ovary Syndrome
Myo-Inositol and Folic Acid for Improving Inflammation in Polycystic Ovary Syndrome
Polycystic Ovary Syndrome (PCOS) is a common endocrine and metabolic disorder affecting women of reproductive age and may be associated with chronic low-grade systemic inflammation.
- Conditions
- Inflammation Biomarkers, Poly Cystic Ovary Syndrome, PCOS (Polycystic Ovary Syndrome)
- Trial name
- NCT07821073
- Testing
- myo-inositol 2000 gm + folic acid 200 mcg
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Khyber Medical University Peshawar
Acute Exacerbation Chronic Obstructive Pulmonary Disease
MxA and CRP-Guided Use of Antimicrobial Agents for AECOPD
This randomized controlled trial will investigate the clinical impact of Myxovirus Resistance A (MxA) and C-Reactive Protein (CRP)-guided antimicrobial treatment compared to usual care in outpatients with acute exacerbations of…
- Trial name
- NCT06779344
- Testing
- MxA and CRP tests, MxA and CRP feedback, Follow up
- Where
- China
- Volunteers
- 458 people
- Sponsor
- Capital Medical University
COVID-19 Pneumonia, ARDS
The Effect of Tocilizumab on Procalcitonin and Other Biochemical and Clinical Markers in the Setting of COVID-19 Pneumonia
This study aims to establish whether tocilizumab has any significant effect on procalcitonin levels on patients diagnosed with COVID-19 pneumonia requiring intensive care admission.
- Trial name
- NCT05035589
- Testing
- Tocilizumab
- Where
- Malta
- Volunteers
- 100 people
- Sponsor
- Sciberras, Stephen M.D.
General Anesthesia, Laparotomy
Comparison of CRP Levels, Neutrophil Count, and Clinical Outcomes of Low Dose Ketamine Between at Anesthesia Induction and at the End of Surgery in Patients Undergo Elective Laparotomy
The effects of anesthesia and surgery can lead to stress responses that result in hormonal and metabolic changes in the body. The immune system and the nervous system communicate both ways, and it was found that nociception and…
- Conditions
- General Anesthesia, Laparotomy, Inflammation
- Trial name
- PRO-Ketamine (NCT04462094)
- Testing
- Ketamine 0.3 mg/kg at end-of-surgery, Ketamine 0.3 mg/kg at anesthesia induction
- Where
- Indonesia
- Volunteers
- 68 people
- Sponsor
- Udayana University
Acute Kidney Injury
Serum Cysteine Rich Protein 61 and Cystatin C for Early Detection of Acute Kidney Injury in Patients With Heart Diseases
Acute Kidney Injury (AKI) is defined as an absolute increase in serum creatinine ≥0.3 mg/dl (≥26.4 μmol/l), a percentage increase in serum creatinine ≥50% (1.5-fold from baseline), or a reduction in urine output (documented…
- Trial name
- NCT05242705
- Testing
- Serum Cysteine Rich Protein 61
- Volunteers
- 45 people
- Sponsor
- Assiut University
COVID-19 (Coronavirus Disease 2019), Hypoxia
Nebulised Dornase Alfa for Treatment of COVID-19 (Coronavirus Disease 2019)
An open-label, randomised, Best-Available-Care (BAC) and historic-controlled trial of nebulised dornase alfa [2.5 mg BID (bis in die)] for 7 days in participants with COVID-19 who are admitted to hospital and are at risk of…
- Trial name
- COVASE (NCT04359654)
- Testing
- Dornase Alfa Inhalation Solution [Pulmozyme]
- Where
- United Kingdom
- Volunteers
- 41 people
- Sponsor
- University College, London
Corona Virus Infection, Pregnancy; Infection
THE RELATIONSHIP OF CRP/ALBUMIN RATIO LEVEL AND PROGNOSIS IN PREGNANT COVID-19 PATIENTS
The CRP/albumin ratio (CAR) is a recently defined parameter which represents the ratio of a positive acute phase reactant to a negative acute phase reactant.
- Trial name
- NCT05242172
- Testing
- CRP/Albumin ratio
- Where
- Turkey (Türkiye)
- Volunteers
- 127 people
- Sponsor
- Adiyaman University Research Hospital
Nasopharyngeal Carcinoma, Head and Neck Cancer
The Association of hsCRP and Radiotherapy-Induced Toxicity in Patients With Nasopharyngeal Carcinoma
The primary purpose of this study is to explore the association of high sensitivity C-reactive protein (hsCRP) and radiotherapy(RT)-induced toxicity in patients with nasopharyngeal carcinoma.
- Conditions
- Nasopharyngeal Carcinoma, Head and Neck Cancer, Toxicity Due to Radiotherapy
- Trial name
- NCT04303975
- Testing
- clinical measurements
- Volunteers
- 300 people
- Sponsor
- Jiarong Chen, MD
Cardiovascular Diseases, Atherosclerosis
Serum Total Homocysteine and C-Reactive Protein - Ancillary to IDNT
To examine the independent association of serum total homocysteine and C-reactive protein with arteriosclerotic cardiovascular disease morbidity and mortality.
- Conditions
- Cardiovascular Diseases, Atherosclerosis, Heart Diseases, Diabetes Mellitus, Non-insulin Dependent
- Trial name
- NCT00021918
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Chronic Inflammation, Overweight
Effect of Palmitoleic Acid on C-reactive Protein
This clinical trial will test the effects of an n-7 monounsaturated fatty acid known as palmitoleic acid (POA) on a chronic inflammation marker in overweight subjects.
- Trial name
- NCT03625427
- Testing
- Palmitoleic acid, 500 mg (Dose 1), Palmitoleic acid, 1,000 mg (Dose 2)
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Leptospirosis
N-Acetylcysteine in Patients With Leptospirosis
The goal of this clinical trial is to learn whether oral N-acetylcysteine (NAC) can reduce markers of kidney tubular injury, oxidative stress, and inflammation in adults with non-severe leptospirosis.
- Trial name
- NCT07821853
- Testing
- N-acetylcysteine
- Where
- Indonesia
- Volunteers
- 64 people
- Sponsor
- Dr Cipto Mangunkusumo General Hospital
Atherosclerosis
Integrated Biomarker And Imaging Study - 2
IBIS-2 is a study using SB-480848 versus placebo in subjects with angiographically documented coronary heart disease. Endpoints include coronary imaging, endothelial function, biomarkers, safety and tolerability.
- Trial name
- NCT00268996
- Testing
- SB-480848
- Where
- 26 sites in Austria, Belgium and 9 more
- Volunteers
- 336 people
- Sponsor
- GlaxoSmithKline
Rheumatoid Arthritis
Can Cytokines be Used as an Activation Marker
RA is a chronic, autoimmune, inflammatory disease that involves small joints in the form of symmetrical polyarthritis and progresses with exacerbations and remissions.
- Trial name
- NCT04486027
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Maltepe University