Clinical trials: CRP
Type 1 Diabetes, Coronary Artery Calcification
Cardiovascular Risk Stratification in Young People With Type 1 Diabetes
The aim of the study is to compare ESC recommendations on cardiovascular (CV) risk stratification with the achievement of a CAC (Coronary Artery Calcification).
- Trial name
- CACD1 (NCT05283538)
- Testing
- Coronary Artery Calcification Realization
- Where
- France
- Volunteers
- 91 people
- Sponsor
- Poitiers University Hospital
STEMI (STE-ACS), Primary PCI for STEMI
The Effect of Atorvastatin 80 mg on Hs-CRP/Albumin Ratio in Reducing Thrombus Burden in PCI-STEMI Patients
40 STEMI patients who underwent primary PCI were subsequently allocated into two groups via a double-blind randomization method: An Atorvastatin 80 mg group and the control group.
- Trial name
- PCI-STEMI (NCT06871358)
- Testing
- Atorvastatin 80mg
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Universitas Sebelas Maret
Obstructive Sleep Apnoea Hypopnoea Syndrome, Biomarkers of Fibrin Clot Structure
New Markers to Measure Clotting in Patients With the Obstructive Sleep Apnoea Hypopnoea Syndrome
Obstructive Sleep Apnoea Hypopnoea Syndrome(OSAHS)affects at least 4% of males and 2% of females. OSAHS is the combination of excessive daytime sleepiness, snoring and apnoeas (stopping breathing at night).
- Conditions
- Obstructive Sleep Apnoea Hypopnoea Syndrome, Biomarkers of Fibrin Clot Structure, Biomarkers of Vascular Endothelial Injury
- Trial name
- NCT01525160
- Where
- United Kingdom
- Volunteers
- 66 people
- Sponsor
- Hywel Dda Health Board
Ankylosing Spondylitis
Lacticaseibacillus Rhamnosus GG Supplementation in Active Ankylosing Spondylitis
The goal of this clinical trial was to learn whether Lacticaseibacillus rhamnosus GG supplementation improves disease activity, physical function, and inflammatory markers in adults with active ankylosing spondylitis.
- Trial name
- NCT07834788
- Testing
- Lacticaseibacillus rhamnosus GG
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- Acibadem University
Acute Hydrocarbon Toxicity
Evaluation of the Role of Poisoning Severity Score, Serum Procalcitonin and C-reactive Protein in Acute Hydrocarbon Intoxicated Cases Admitted to the Poison Control Center Ain Shams University Hospitals
Hydrocarbons are a primary energy source in modern society. They are present in many common household and occupational products, including motor fuels, paint thinners, cleaning agents, lotions, and industrial solvents.
- Trial name
- NCT06151301
- Testing
- serum procalcitonin, C-reactive protein
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University
Periodontitis, Kidney Transplant Recipients
Diode Laser-Assisted Periodontal Therapy in Kidney Transplant Recipients
This randomized controlled trial evaluates the efficacy of diode laser-assisted non-surgical periodontal therapy in kidney transplant recipients with periodontitis.
- Trial name
- KTRs (NCT07532694)
- Testing
- Scaling and Root Planing, Diode Laser
- Where
- 2 sites in Vietnam
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Military Hospital 103
Periodontal Diseases
Comparison of Salivary Biormarkers Levels With Periodontal Clinical Parameters in Smokers and Non-Smokers With Different Periodontal Diseases
To better understand the pathogenesis of chronic inflammatory diseases, the levels of various cytokines are commonly analyzed in tissues and biological fluids collected from the body.
- Trial name
- NCT06459037
- Testing
- Saliva obtaining
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Stable Angina, Heart Failure
Association Between Inflammatory Biomarkers in CVD Patients on Empagliflozin.
The association of novel inflammatory biomarkers with cardiovascular diseases is still obscure. The present study aimed to investigate the relationship of various inflammatory biomarkers with the existence as well as the extent…
- Trial name
- NCT05911724
- Testing
- Group I Healthy, CAD-Empagliflozin 10 mg once daily for 6 months before the beginning of the study, HF-Empagliflozin 10 mg once daily for 6 months before the beginning of the study
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Damanhour University
Inflammation, Infections
A Performance Evaluation of the LumiraDx Point of Care CRP Assay
In patients with symptoms of infection, tissue injury and inflammatory disorders the study will evaluate agreement between the CRP measurements from the LumiraDx POC CRP assay and the Siemens Dimension Xpand Plus CRP assay, as an…
- Conditions
- Inflammation, Infections, Tissue Injury
- Trial name
- REACT (NCT05180110)
- Testing
- Venepuncture, Fingerstick
- Where
- 3 sites in United Kingdom
- Volunteers
- 79 people
- Sponsor
- LumiraDx UK Limited
Sepsis, Osteoporotic Hip Fracture
Prediction of Mortality and Morbidity After Hip Fracture Using Monocyte Distribution Width (MDW)
Hip fracture is a common injury in older adults and is often associated with serious complications, longer hospital stays, and increased risk of death.
- Conditions
- Sepsis, Osteoporotic Hip Fracture, Hip Fracture
- Trial name
- MDW (NCT07350785)
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- National and Kapodistrian University of Athens
Low Back Pain
Effectiveness of Theramine on Chronic Back Pain
This research protocol will compare Theramine to a non-steroidal anti-inflammatory drug (NSAID) in the treatment of chronic back pain.
- Trial name
- NCT01468025
- Testing
- Active Theramine and Active Naproxen
- Volunteers
- 127 people
- Sponsor
- Targeted Medical Pharma
Fever, Heart Rate
Urinary Catheter Exchange on Admission of Septic Elderly With Permanent Catheter Before Initiation of Antibiotics
In the era of emerging antibiotics resistant microbiology, we look for better outcome in the treatment of infections in the elderly.
- Conditions
- Fever, Heart Rate, Blood Pressure, C-Reactive Protein
- Trial name
- NCT00503282
- Sponsor
- Shaare Zedek Medical Center
Atherosclerosis, Inflammation
Nutraceutical Combination in Patients With Low-grade Systemic Inflammation
The investigators tested if a nutraceutical combination with red yeast rice, berberine and policosanol (NC) can significantly modify inflammation, lipid profile and markers of endothelial injury (endothelial microparticles) in…
- Conditions
- Atherosclerosis, Inflammation, Hypercholesterolemia
- Trial name
- NCT02422927
- Testing
- Nutraceutical Combination, Standard of Care
- Volunteers
- 100 people
- Sponsor
- University Of Perugia
Major Depressive Disorder
Mindfulness-Based Cognitive Therapy Effect on Depression and C-Reactive Protein Levels After 8 Weeks of Treatment
This study will investigate the efficacy of an 8-week course in Mindfulness-Based Cognitive Therapy (MBCT) for adults with major depressive disorder (MDD) by ;measuring change from baseline to completion of treatment at 8 weeks…
- Trial name
- NCT02385786
- Testing
- Mindfulness-Based Cognitive Therapy
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Burn
THE EFFECT OF CRP/LYMPHOCYTE AND NEUTROPHIL/LYMPHOCYTE RATIOS ON LENGTH OF HOSPITAL STAY AND MORTALITY IN PATIENTS ADMITTED TO THE BURN UNIT
This retrospective study aims to evaluate the prognostic value of systemic inflammatory markers, specifically the C-reactive protein-to-lymphocyte ratio (CLR) and neutrophil-to-lymphocyte ratio (NLR), in patients admitted to the…
- Trial name
- C REACTIVE PRO (NCT07855432)
- Testing
- Routine blood samples collected for CRP, neutrophil, and lymphocyte counts during ICU admission.
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Samsun University
Renal Insufficiency
Anti-inflammatory Effect of Atorvastatin on Graft Donor Kidney
Renal Insufficiency is a priority disease in health system, which may require renal replacement therapy based on renal transplantation, which is considered as therapy of choice.
- Trial name
- NCT02355704
- Testing
- Atorvastatin
- Where
- Mexico
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Instituto Mexicano del Seguro Social
Malondialdehyde, Heme Oxygenase
The Effects of Two Anesthetic Drugs on Some Enzyme Levels in Patients Undergoing Lower Extremity Surgery
The primary aim of this study was to compare the effects of dexmedetomidine and ketamine, which are administered intravenously during surgery, on the levels of malondialdehyde, an antioxidant, anti-inflammatory enzyme, heme…
- Conditions
- Malondialdehyde, Heme Oxygenase, C-Reactive Protein
- Trial name
- NCT05950555
- Testing
- Saline, Dexmedetomidine, Ketamine
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ataturk University
Critically Ill, Sepsis
Early Diagnostic Biomarkers of Sepsis
A Comparison between CRP, ferritin, and serum zinc as early diagnostic biomarkers of sepsis in critically ill patients
- Trial name
- NCT05112406
- Volunteers
- 70 people
- Sponsor
- Assiut University
Bipolar Depression
Brexpiprazole Treatment for Bipolar I Depression
Bipolar disorder (BD) is a frequent and lifelong recurrent mood disorder with treatment-resistant depressive episodes. Importantly, depressive symptoms and cognitive decline are major determinants of functionality and quality of…
- Trial name
- NCT04569448
- Testing
- Brexpiprazole
- Where
- 3 sites in Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Douglas Mental Health University Institute
Metabolic Dysfunction-associated Fatty Liver Disease, Hepatic Steatosis
Association of HsCAR with MAFLD and Liver Fibrosis: a Cross-sectional Study
The goal of this observational study is to investigate the associations between a novel inflammatory marker, high sensitivity C-reactiveprotein to albumin ratio (hsCAR), and steatosis and fibrosis of metabolic…
- Conditions
- Metabolic Dysfunction-associated Fatty Liver Disease, Hepatic Steatosis, Liver Fibrosis
- Trial name
- NCT05974904
- Testing
- high-sensitivity C-reactive protein to albumin ratio
- Where
- China
- Volunteers
- 7,000 people
- Sponsor
- Chongqing Medical University