Clinical trials: CRP
Atherosclerosis, Diabetes
Strategies for Inflammation and Cardiovascular Disease (CVD) Prevention
The long-term goal of the proposed research is to identify and develop effective interventions to decrease persistent, low-level inflammation and risk of CVD.
- Trial name
- SICVDP (NCT02165228)
- Testing
- Mindfulness-based stress reduction, Nutrition Enhancement
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Montana State University
Acute Coronary Syndrome
Relationship Between Inflammatory (Hs-CRP, Neutrophil-to-Lymphocyte Ratio) and Cardiac (Troponin) Biomarkers, and Cardiac Dysfunction in Acute Coronary Syndrome.
Acute Coronary Syndrome (ACS) remains a leading cause of morbidity and mortality worldwide, accounting for a significant proportion of cardiovascular-related deaths.
- Trial name
- NCT07551102
- Volunteers
- 144 people
- Sponsor
- Assiut University
Chronic Obstructive Pulmonary Disease
Effects of Inhaled Corticosteroids in the Systemic Inflammation Induced by Exercise in Patients With COPD
Chronic obstructive pulmonary disease (COPD) is characterized by pulmonary and systemic inflammation. The effect of inhaled corticosteroids (IC) on inflammation in COPD is controversial.
- Trial name
- NCT02209974
- Testing
- Fluticasone
- Where
- Spain
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Hospital Son Llatzer
Sepsis, SIRS
Performance Evaluation of the Nanomix eLab® CRP, PCT, and LAC Assays With the Nanomix eLab System
The performance of the eLab C-Reactive Protein, Procalcitonin, and Lactate Assays will be demonstrated during a method comparison study in which venous whole blood and plasma samples are used.
- Trial name
- NCT03876535
- Testing
- Nanomix eLab® System molecular diagnostic test (non-interventional)
- Where
- United States
- Volunteers
- 184 people
- Sponsor
- Nanomix
Respiratory Infections in Children
Improving Antibiotic Stewardship for Children With Respiratory Illness Presenting to Village Health Workers in Uganda
This is a stepped wedge, cluster randomized study of a clinical algorithm that includes point-of-care C-reactive protein testing to inform antibiotic treatment decisions by village health workers for children presenting with…
- Trial name
- STAR (NCT05294510)
- Testing
- STAR Sick Child Job Aid
- Where
- Uganda
- Volunteers
- 1,280 people
- Sponsor
- University of North Carolina, Chapel Hill
Rheumatoid Arthritis, Vascular Inflammation
Etanercept in Rheumatoid Arthritis and Vascular Inflammation
The primary goal of this preliminary project is to study the effect of etanercept, a medicine approved by Health Canada for the treatment of rheumatoid arthritis, on the inflammation of certain blood vessels.
- Trial name
- NCT02109289
- Testing
- etanercept
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- Innovaderm Research Inc.
Hyperreactive Airway
Evaluating the Capacity of High-sensitivity Serum CRP Levels to Predict Bronchial Hyper Responsiveness in School Age Children
Background: Bronchial hyper responsiveness (BHR) assessed by methacholine challenge test (MCT) may aid in the diagnosis of asthma, while negative MCT can help to exclude the diagnosis.
- Trial name
- NCT01963585
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Healthy
Enhancing Emotional and Motivational Development to Support Well-being and Retention in Diverse University Students
Higher education is crucial for young adults in their intake of knowledge and skills to further their careers and reach their potentials. However, going through college is not necessarily an easy path.
- Trial name
- NCT05294913
- Testing
- Contextualized Wish-Outcome-Obstacle-Plan (WOOP) intervention
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Mortality, Hyperhomocysteinemia
5-methyltetrahydrofolate Survival and Inflammation in ESRD Patients
A randomized prospective study was done to determine whether i.v. 5-methyltetrahydrofolate vs oral folate improved survival in ESRD patients. Homocysteine, CRP, Lp(a), albumin, folates, vitamin B6 and B12 were checked.
- Conditions
- Mortality, Hyperhomocysteinemia, Inflammation
- Trial name
- NCT00626223
- Testing
- 5-MTHF (5-methyltetrahydrofolate), folic acid
- Where
- Italy
- Volunteers
- 341 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
SIRS, Sepsis
The Value of sTREM-1, PCT, and CRP as Markers for the Detection of Sepsis and Bacteremia Among Patients With a FUO
The investigators enrolled 144 subjects admitted to ICUs: 60 patients with systemic inflammatory response syndrome (SIRS) and 84 patients with sepsis.
- Conditions
- SIRS, Sepsis, Bacteremia
- Trial name
- NCT01410578
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Chinese PLA General Hospital
Depressive Disorder, Post-Acute COVID-19 Syndrome
IMPACT-D+: Immune-Modulating and Psychometric Effects of Accelerated TMS in Depression Plus Comorbid Post-COVID-19 Condition
This is a monocentric, randomized pilot study conducted at the Max Planck Institute of Psychiatry, Munich. The study investigates the effects of two different intermittent theta-burst stimulation (iTBS) schedules on biological…
- Trial name
- IMPACT-D+ (NCT07197138)
- Testing
- Intermittent theta-burst stimulation (iTBS) using PowerMAG 100 ppTMS
- Where
- Germany
- Volunteers
- 42 people
- Sponsor
- Max-Planck-Institute of Psychiatry
Major Depressive Disorder
Lipopolysaccharide (LPS) Challenge in Depression
LPS Challenge in Individuals with Major Depressive Disorder
- Trial name
- NCT03142919
- Testing
- Lipopolysaccharide
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Colorectal Cancer
Comparison of Probiotic Effects on the Outcomes of Patients After Colorectal Cancer Surgery
This clinical trial aims to compare the effects of administering Lactobacillus casei Shirota probiotics with Lactobacillus acidophilus on the outcomes of patients after colorectal cancer surgery.
- Trial name
- NCT07144475
- Testing
- Lactobacillus casei Shirota, Lactobacillus acidophilus
- Where
- Indonesia
- Volunteers
- 90 people
- Sponsor
- Dharmais National Cancer Center Hospital
Essential Hypertension
Safety and Efficacy of Ramipril in the Treatment of Essential Hypertension
The purpose of this study is to assess which drug is more effective of Ramiprin®(ramipril) and Tritace®(ramipril) in the Treatment of Essential Hypertension
- Trial name
- NCT00366119
- Testing
- Ramipril
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- Pacific Pharmaceuticals
Diagnostic Role, Prognostic Role
Diagnostic and Prognostic Roles of Procalcitonin and Highly Sensitive C-Reactive Protein in Early Detection of Burn Sepsis
This study aimed to evaluate the value of procalcitonin and highly sensitive c-reactive protein as biomarkers for early detection of sepsis in patients with major burns.
- Conditions
- Diagnostic Role, Prognostic Role, Procalcitonin, Highly Sensitive
- Trial name
- NCT07791030
- Testing
- Measurement of Procalcitonin level, Measurement of c-reactive protein level
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Obstructive Sleep Apnea
Change in C-reactive Protein (CRP) in Men and Women With Sleep Apnea After Continuous Positive Airway Pressure (CPAP)
C-reactive protein (CRP) is directly implicated in atherogenesis and associated cardiovascular morbidity in patients with obstructive sleep apnea (OSA).
- Trial name
- NCT01365832
- Testing
- Continuous Positive Airway Pressure (CPAP)
- Where
- Greece
- Volunteers
- 436 people
- Sponsor
- University of Crete
Advanced Malignant Solid Neoplasm, C-Reactive Protein Measurement
Anamorelin Hydrochloride, Physical Activity, and Nutritional Counseling in Decreasing Cancer-Related Fatigue in Patients With Incurable Metastatic or Recurrent Solid Tumors
This phase II trial studies how well anamorelin hydrochloride, physical activity, and nutritional counseling work in decreasing cancer-related fatigue in patients with incurable solid tumors that have spread to other parts of the…
- Conditions
- Advanced Malignant Solid Neoplasm, C-Reactive Protein Measurement, Cancer Fatigue, Metastatic Malignant Solid Neoplasm
- Trial name
- NCT03035409
- Testing
- Anamorelin Hydrochloride, Exercise Intervention, Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- M.D. Anderson Cancer Center
Crohn's Disease
Study to Evaluate the Pharmacokinetics, Safety and Efficacy of Two Treatment Modules in Chinese Subjects With Moderate to Severe Crohn's Disease
The purpose of this study is to investigate the efficacy, safety, and pharmacokinetics of adalimumab following subcutaneous (SC) administration of 2 dosing regimens in Chinese subjects with Crohn's disease.
- Trial name
- NCT02015793
- Testing
- Adalimumab
- Volunteers
- 30 people
- Sponsor
- AbbVie
Community-acquired Pneumonia
Procalcitonin Versus C-reactive Protein to Guide Therapy in Community Acquired Pneumonia
In this study the investigators aim to test if C-reactive protein (CRP) or procalcitonin(PCT) - guided strategy allows to reduce the antibiotic use in patients wiht community-acquired pneumonia.
- Trial name
- CAP-Marker (NCT01018199)
- Testing
- CRP, PCT
- Where
- Brazil
- Sponsor
- Federal University of Minas Gerais
End-Stage Renal Disease, Hemodialysis Complication
Effects of Mindfulness Meditation on Hemodialysis Patients
Objective: This study aimed to examine the effects of mindfulness meditation on the quality of sleep, perceived stress, serum cortisol, and C-reactive protein in end-stage renal disease patients undergoing hemodialysis.
- Trial name
- RCT (NCT06936293)
- Testing
- Mindfulness Meditation
- Where
- Kuwait
- Volunteers
- 56 people
- Sponsor
- University of Jordan