Clinical trials: CRP
Antibiotic Prescribing for Acute Respiratory-tract Infections
Effect of CRP and SAA Point-of-care Testing on Antibiotic Prescribing for Acute Respiratory-tract Infections
The study was a practical, cluster-randomized controlled trial to evaluate the impact of CRP and SAA point-of-care testing (CRP\&SAA POCT) on antibiotic prescribing in patients with acute respiratory-tract infections (ARI) at…
- Trial name
- NCT06568432
- Testing
- CRP+SAA POCT
- Where
- China
- Volunteers
- 35,108 people
- Sponsor
- Huazhong University of Science and Technology
Atherosclerosis
Double-Blind, Randomized, Placebo-Controlled Trial of MLN1202 on C-Reactive Protein Levels in Patients With Risk Factors for Cardiovascular Disease
This study is a, randomized, double-blind, placebo-controlled phase 2a trial evaluating the potential of MLN1202 to reduce circulating levels of C-reactive protein (CRP)in patients with risk factors for Atherosclerotic…
- Trial name
- NCT00715169
- Testing
- MLN1202
- Volunteers
- 108 people
- Sponsor
- Millennium Pharmaceuticals, Inc.
Aortic Arch Hypoplasia or Atresia
Modified Perfusion for Neonatal Aortic Arch Reconstruction
Even though the lower part of the body does receive some blood supply during Cardiopulmonary Bypass(CPB) surgery, it may not be enough.
- Trial name
- NCT00490256
- Testing
- Modified Selective Cerebral Perfusion
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Emory University
Chronic Kidney Disease, Inflammation
Synbiotic Supplementation and Inflammation in Predialysis Chronic Kidney Disease
Chronic kidney disease (CKD) is a long-term condition in which the kidneys gradually lose their ability to function properly. People with chronic kidney disease (CKD) often experience chronic inflammation and digestive symptoms…
- Trial name
- SSIPCKD (NCT07430280)
- Testing
- Synbiotic Supplement
- Volunteers
- 100 people
- Sponsor
- Centenario Hospital Miguel Hidalgo
Acute Diverticulitis
Acute Diverticulitis and C-Reactive Protein as a Prognostic Marker
The management of acute diverticulitis maybe better if we have prognostic markers of evolution. Hypothesis: C-reactive protein maybe a good prognostic marker of evolution of acute diverticulitis.
- Trial name
- NCT01825967
- Testing
- C-reactive protein
- Where
- 4 sites in Spain
- Volunteers
- 30 people
- Sponsor
- Corporacion Parc Tauli
Acute Coronary Syndromes
Effects of the Ivabradine on Reduction of Inflammatory Markers in Patients With Acute Coronary Syndrome
The purpose of this study is to investigate whether a pure heart rate-lowering agent (Ivabradine) reduces vascular inflammatory stress in patients with acute coronary syndromes
- Trial name
- NCT00815100
- Testing
- Ivabradine
- Where
- Spain
- Volunteers
- 27 people
- Sponsor
- Hospital Universitario de Canarias
OSA
Fractional Exhaled Nitric Oxide and CRP Levels in Egyptian Patients With Obstructive Sleep Apnea Syndrome
Obstructive sleep apnea syndrome (OSAS) was associated with upper and lower respiratory tract inflammation, Fractional exhaled nitric oxide (FeNO) proposed as a marker of airway inflammation, few studies were done on the impact…
- Trial name
- NCT04179942
- Testing
- Fractional exhaled nitric oxide and CRP levels
- Where
- Egypt
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Juvenile Idiopathic Arthritis
Pharmacokinetics, Efficacy and Safety of Olokizumab In Patients With Juvenile Idiopathic Arthritis
The primary objective of this study is to evaluate the pharmacokinetics (PK) of olokizumab (OKZ) in patients with polyarticular juvenile idiopathic arthritis aged >2 and <18 years in two doses (64 mg or 48 mg every 4 weeks)…
- Trial name
- NCT07517575
- Testing
- OKZ q4w
- Where
- 14 sites in Russia
- Volunteers
- 71 people
- Sponsor
- R-Pharm International, LLC
Thalassemia
Adiponectin, IL-6 and hsC-RP in Relation to Carotid Intima-media Thickness in B-thalassemia Patients
Every year, 100,000 neonates are born with hemoglobinopathies around the world. Thalassemia is the most common heterogeneous disease of the human being .
- Trial name
- NCT03170245
- Testing
- Interleukin-6, HsC-RP, Adiponectin level
- Where
- Egypt
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Assiut University
Healthy
Effect of Dietary Fat Type in Combination With High Protein on Plasma Homocysteine Levels
In this study, the investigators address the research question of whether palm olein will have a positive influence on plasma total homocysteine levels in human volunteers provided with high-protein diets formulated from common…
- Trial name
- NCT00941837
- Testing
- Olive Oil, Palm Olein Oil, Coconut Oil
- Where
- Malaysia
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Malaysia Palm Oil Board
Adults, Acute Respiratory Tract Infection
The C-reactive Protein (CRP) Point of Care Testing (POCT) Implementation to Adult Patients Presenting With Symptoms of the Acute Respiratory Tract Infection (ARTI) in Eight Primary Health Care (PHC) in Jakarta.
Antimicrobial resistance (AMR) has emerged as one of the most pressing global health challenges of the 21st century, particularly Indonesia is projected to be among the five nations globally with the highest percentage increase…
- Conditions
- Adults, Acute Respiratory Tract Infection, Antibiotic Prescriptions
- Trial name
- INA IMPACT-RTI (NCT07717372)
- Testing
- Implementation group
- Where
- 8 sites in Indonesia
- Volunteers
- 2,544 people, healthy volunteers welcome
- Sponsor
- Oxford University Clinical Research Unit Indonesia
Chronic Periodontitis
Omega-3 Fatty Acids in Chronic Periodontitis.
Omega 3 fatty acids is one such dietary supplement, known to modulate the host response in chronic conditions like cardiovascular diseases, rheumatoid arthritis, ischemic cerebrovascular diseases, osteoporosis by producing…
- Trial name
- omega3 (NCT01997853)
- Testing
- Omega 3 fatty acid
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tatyasaheb Kore Dental College
IBD-Inflammatory Bowel Disease, UC - Ulcerative Colitis
Impact of Therapeutic Intervention on Quality of Life in Patients With Ulcerative Colitis
This study is therefore postulated as a clear alternative that evaluates patients´quality of life, and recognises fecal calprotectin as an inflammatory marker.
- Trial name
- CAVI_CU (NCT05271773)
- Where
- 10 sites in Spain
- Volunteers
- 234 people
- Sponsor
- Grupo Espanol de Trabajo en Enfermedad de Crohn y Colitis Ulcerosa
Ovarian Neoplasms Malignant, Anastomotic Leak
Early Dehiscence Markers in Ovarian Cancer Surgery
EDMOCS trial pretends to evaluate if C-reactive protein (CRP) and procalcitonin (PCT) can predict intestinal anastomotic leaks before early discharge in advanced ovarian cancer surgery requiring intestinal resection.
- Trial name
- EDMOCS (NCT03131492)
- Testing
- Blood test
- Where
- Spain
- Volunteers
- 92 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Inflammation
Effect of Oleic Acid on Inflammation Markers and Blood Lipid Metabolites: A Randomised, Double-Blind, Crossover Study
Rationale: The effect of positional distribution of dietary fatty acids on markers of inflammation and blood lipids metabolites on diets containing fatty acids such as oleic acid that are associated with reduced risk of…
- Trial name
- NCT00715312
- Testing
- Novel Olein
- Where
- Malaysia
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Malaysia Palm Oil Board
Burns
Pilot Trial of Statin Use in Burn Patients
This is a 90 day study, with patients receiving either oral Rosuvastatin or placebo for up to 28 days. The study will assess the affect of statins administered soon after burn injury on C-reactive protein (CRP) levels, patient…
- Trial name
- BURNSTAT (NCT00978419)
- Testing
- Rosuvastatin
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Vanderbilt University Medical Center
Bacterial Infections, Viral Infection
The Rate of C-reactive Protein (CRP) Increase as a Marker for Bacterial Infections in Children
Fever is one of the most common problems in pediatrics. Differentiating between bacterial infections, that require antibiotic therapy, and viral infections that resolve on their own is an important challenge for physicians.
- Trial name
- CRPv (NCT01159470)
- Volunteers
- 200 people
- Sponsor
- Shaare Zedek Medical Center
Ulcerative Colitis
Composite Ratios Boost CRP's Power in Monitoring Ulcerative Colitis.
Inflammatory Bowel Disease (IBD) is a chronic, recurrent condition marked by disturbed levels of various hematological inflammatory cells and a deregulated immune environment.
- Trial name
- NCT07261579
- Testing
- C-Reactive Protein measuring CRP, CRP to Albumin Ratio
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Benha University
Covid19
CRP-Apheresis for Attenuation of Pulmonary, MYocardial and/or Kidney Injury in COvid-19
The 'CAPMYKCO' study is a randomized controlled, open-label, single center proof of concept trial. The aim of this study is to evaluate whether a CRP-apheresis in addition to the current standard therapy is intended to mitigate…
- Trial name
- CAPMYKCO (NCT04898062)
- Testing
- CRP-apheresis
- Where
- 4 sites in Germany
- Sponsor
- Pentracor GmbH
IBS
Probiotic in Irritable Bowel Syndrome (IBS) Patients With Diarrhea
We present the study design of a clinical trial designed to assess the clinical effects of the multispecies probiotic combination "BIO-25" in IBS-D patients.
- Trial name
- IBS-D (NCT01667627)
- Testing
- Bio-25
- Where
- Israel
- Volunteers
- 107 people
- Sponsor
- Tel-Aviv Sourasky Medical Center