Clinical trials: CRP
Periodontitis, Polycystic Ovary Syndrome
Evaluation of Periodontal Status and hsCRP Levels in Females With PCOS on CPA/EE Combination Drug Regimen
PCOS is a widely reported condition among young female population and anti-androgen agents are increasingly being used as part of the medical management of such cases.
- Conditions
- Periodontitis, Polycystic Ovary Syndrome, Gingivitis
- Trial name
- NCT05021861
- Testing
- Cyproterone Acetate, Ethinyl Estradiol Drug Combination, FEMALE PATIENTS WITH PCOS, Control group
- Where
- India
- Volunteers
- 150 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Type 2 Diabetes Mellitus With Periodontal Complication, Inflammation
Taking Out All Teeth and Replacing Them With Dentures That Rest on Implants in People With Type 2 Diabetes
Gum disease and type 2 diabetes are common chronic diseases that affect each other. Diabetes is increasing, especially in Pakistan. People with diabetes have a greater risk for gum disease.
- Conditions
- Type 2 Diabetes Mellitus With Periodontal Complication, Inflammation, Dental Implant Failed
- Trial name
- NCT01774942
- Testing
- Procedure/Surgery
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- University of Michigan
Rheumatoid Arthritis (RA)
Evaluation of Dapagliflozin and Empagliflozin as Adjunctive Therapy to Methotrexate in Patients With Rheumatoid Arthritis
This study aims to evaluate the efficacy and safety of dapagliflozin and empagliflozin as adjunctive therapies to methotrexate in patients with rheumatoid arthritis who have active disease despite stable methotrexate treatment.
- Trial name
- NCT07864688
- Testing
- Dapagliflozin, Empagliflozin, Methotrexate
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Al-Azhar University
Type 1 Diabetes
Monocyte Function and Inflammation in Type 1 Diabetes and Its Modulation
Type I diabetes (T1DM) is associated with an increased risk of vascular complications. While the precise mechanism(s) by which diabetes accelerates atherosclerosis has not been elucidated, several lines of evidence point to the…
- Trial name
- NCT00441844
- Testing
- Simvastatin
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, Davis
Abdominal Obesity
Effect of Replacing HFCS With Sucromalt in Subjects With Raised Waist Circumference
Weight gain is linked to a high consumption of soft-drinks and other beverages sweetened with high fructose corn syrup. Being overweight increases risk for diabetes and heart disease.
- Trial name
- NCT00374218
- Testing
- High Fructose Corn Syrup, Sucromalt
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Cardiovascular Diseases
Happy Gut Study - Fermented Vegetables and Cardiovascular Biomarkers
The purpose of this project is to determine whether regular consumption of fermented vegetables can decrease inflammation and change the types of bacteria that are normally present in the large intestine.
- Trial name
- NCT04887662
- Testing
- Fermented vegetable
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of North Florida
Inflammation
Beef Burger Versus a Vegetarian Burger
The purpose of this graduate student research study is to compare the rise of serum lipids, glucose, and hs-CRP levels after consumption of a beef burger versus a vegetarian burger in healthy adults between the ages of 21 and 55
- Trial name
- NCT04034160
- Testing
- vegetarian burger, beef burger
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Primary Dysmenorrhea (PD)
The Relationship Between Ophiocephalus Striatus Extract and Serum TNF-α, IL-6, and CRP Levels in Primary Dysmenorrhea
Primary dysmenorrhea is menstrual pain without any underlying pelvic disease. It affects many adolescent girls and can disrupt daily activities, school attendance, and quality of life.
- Trial name
- NCT07677462
- Testing
- Ophiocephalus striatus extract
- Where
- Indonesia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitas Sriwijaya
Vitamin D Deficiency, Chronic Pain Syndrome
The Immune and Clinical Impacts of Vitamin D in Patients With Chronic Musculo-skeletal Pain
Vitamin D3 is produced in the skin following exposure to UVB light from the sun or artificial sources, and occurs naturally in a small range of foods.More recently, several reports underlined the impact of vitamin D on the…
- Conditions
- Vitamin D Deficiency, Chronic Pain Syndrome, Inflammatory Response
- Trial name
- NCT01417923
- Testing
- vitamin D
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Meir Medical Center
Depressive Disorder, Major
Peripheral Immunomarker Validation in Treatment-resistant Depression
This is a study to characterise the role of inflammatory processes in depression. There is compelling evidence that inflammation is often associated with, and can cause, depression.
- Trial name
- BIODEP (NCT02752178)
- Testing
- MA, DEP
- Where
- 5 sites in United Kingdom
- Volunteers
- 393 people, healthy volunteers welcome
- Sponsor
- University of Cambridge
Atrial Fibrillation
Usefulness of Markers to Predict Recurrence of Atrial Fibrillation After Radiofrequency Catheter Ablation
Catheter ablation using radiofrequency is a new therapeutic tool to treat atrial fibrillation with a higher success rate than medical therapy (80% versus less than 50% respectively).
- Trial name
- NCT00315068
- Where
- Switzerland
- Volunteers
- 180 people
- Sponsor
- University Hospital, Geneva
Hyperlipidemia
Standard Process 21 Day Purification Program Project
To determine the effects of a commercially available dietary modification plus nutritional supplement regimen, the Standard Process 21 day Purification Program (SPPP), on serum lipids, C-reactive protein (CRP), homocysteine, body…
- Trial name
- SPPP (NCT00724217)
- Testing
- Standard Process 21 Day Purification Program (SPPP)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Logan College of Chiropractic
Impacted Third Molar Tooth
Anti Inflammatory and Analgesic Effect of Ginger Powder in Dental Pain Model
Ginger contains constituents with pharmacological properties similar to the novel class of dual-acting NSAIDs. Compounds in this class inhibit arachidonic acid metabolism via the cyclooxygenase (COX) and lipooxygenase (LOX)…
- Trial name
- GPE (NCT01429935)
- Testing
- Ginger powder, Ibuprofen
- Where
- 2 sites in Iran
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Qazvin University Of Medical Sciences
Acute Appendicitis
Diagnostic Importance of the C-reactive Protein From Blood and Saliva in Children With Acute Appendicitis
Diagnosing acute appendicitis in children is still a challenge even for experienced clinicians. Failure to recognize this acute condition can result in perforation, with consequent peritonitis, or misdiagnosis can result in…
- Trial name
- NCT06051825
- Testing
- Blood specimen collection for C-reactive protein (CRP) and WBC (white blood cells). Saliva specimen collection for analysis of CRP levels
- Volunteers
- 100 people
- Sponsor
- University Hospital of Split
Anastomotic Leakage in Colon Surgery
Predictive Value of Procalcitonin, CRP, Drain Fluid Culture, Il-6 and Tnf-α in Anastomotic Leakage
Evaluating predictive value of serum procalcitonin, C-Reactive Protein, drain IL-6 and TNF-alpha for anastomotic leakage in post-operative period.
- Trial name
- NCT02361918
- Testing
- Colon surgery
- Volunteers
- 50 people
- Sponsor
- Istanbul University
Temporomandibular Joint Disorders
Evaluation of C-reactive Protein Level in the Group of Patient With Pain Form of Temporomandibular Joint Dysfunction
Temporomandibular joints dysfunction is a functional disorder concern with the abnormal functioning of the muscles of the stomatognathic system, temporomandibular joints involved in the dynamic movements of the jaw and…
- Trial name
- NCT03065608
- Volunteers
- 72 people
- Sponsor
- Jagiellonian University
Impacted Lower Third Molar
Antibiotic Therapy in Impacted Mandibular Third Molar Surgery
This study compared three antibiotic approaches in healthy young adults undergoing surgical removal of impacted lower wisdom teeth: a single dose of antibiotics before surgery, antibiotic treatment after surgery, and no…
- Trial name
- NCT07817940
- Testing
- Amoxicillin-Clavulanate 875 Mg-125 Mg Oral Tablet
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Migraine, Tension-Type Headache
Salivary Inflammatory Markers in Tension Type Headache and Migraine
Data role of salivary inflammatory markers in migraine and Tension Type headache (TTH) are lacking. Τhe investigators studied whether headache attacks are associated with changes in C reactive protein (CRP), Interleukin -1β and…
- Trial name
- SalHead (NCT03727672)
- Where
- Greece
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Gestational Diabetes Mellitus in Pregnancy
Can Albumin/C-reactive Protein Ratio be Utilized for Predicting Gestational Diabetes Diagnosis or the Adverse Outcomes
This study provides a comprehensive evaluation of the potential utility of the albumin/high-sensitivity C-reactive protein (hsCRP) ratio in diagnosing gestational diabetes mellitus (GDM) and predicting adverse pregnancy outcomes.
- Trial name
- Alb/hsCRP (NCT06761053)
- Testing
- Intervention/Exposure for the GDM Group (Experimental Arm), Intervention/Exposure for the Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemalpasa Government Hospital
Sepsis, Systemic Infection
CRP,CRP/Alb Ratio, N/L Ratio in Predictors of Both Systemic Infection and Survival in Patient With Sepsis in Assiut University Hospitals
the goal of this study is to asses the value of biomarker (CRP, CRP/Alb ratio, N/L ratio) in predictor of the outcome in normotensive patients with sepsis.
- Trial name
- NCT06586372
- Volunteers
- 100 people
- Sponsor
- Assiut University