Clinical trials: CRP
Crohn's Disease
Study to Evaluate the Safety and Efficacy of Adalimumab in Chinese Subjects With Moderate to Severe Crohn's Disease
This study will evaluate the efficacy and safety of adalimumab induction and maintenance treatment in subjects with moderately to severely active Crohn's disease in China.
- Trial name
- NCT02499783
- Testing
- adalimumab
- Volunteers
- 205 people
- Sponsor
- AbbVie
Vascular Formation
Effect of Regular Exercise on Vascular Function and Cardiovascular Risk in a Sedentary Work Force
This study will evaluate the effects of NHLBI's employee exercise program, Keep the Beat, on blood vessel function. Damage to blood vessels can cause narrowing of the vessels, resulting in reduced blood flow to parts of the body…
- Trial name
- NCT00246883
- Testing
- Exercise
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Acute Coronary Syndrome
Serum Tenascin-C Concentration in Patients With Acute Coronary Syndrome
This study valuates the serum Tenascin-C concentration in patients with acute coronary syndrome.
- Trial name
- NCT02767960
- Where
- China
- Volunteers
- 183 people
- Sponsor
- The First Affiliated Hospital of Dalian Medical University
Infection Systemic
Duration of Antibiotic Therapy in Critically Ill Patients: C-reactive Protein-guided Therapy Versus Best Practice
The judicious use of antibiotics is one of the main measures to limit the emergence of multidrug-resistant pathogen related to excessive antimicrobial use.
- Trial name
- NCT02987790
- Testing
- C-reactive protein
- Where
- Brazil
- Volunteers
- 135 people
- Sponsor
- Federal University of Minas Gerais
Crohn Disease, Ileocolic Resection
CRP Monitoring After ICR in CD Patients
Aim: The aim of this study was to assess the accuracy of the C-reactive protein as an early predictor of intra-abdominal septic complicationss after ileocolic resection for Crohn disease.
- Trial name
- C-ICR-CD (NCT04643496)
- Testing
- Laparoscopic or open Ileocolic resection
- Where
- France
- Volunteers
- 159 people
- Sponsor
- University Hospital, Montpellier
Inflammation
The Effect of a Nutritional Supplement Product Containing Cactus Fruit Juice (Nopalea) on C-Reactive Protein
This study has been developed to investigate the anti-inflammatory effects of a commercial product (Nopalea) containing Prickly Pear Cactus Fruit Juice in healthy adults.
- Trial name
- NOPALEA (NCT01881178)
- Testing
- NOPALEA
- Where
- United States
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- Mark Mattie
Stroke, National Institutes of Health Stroke Scale
Multivariate Analysis of Serum High Sensitivity C-Reactive Protein in Patients With Acute Phase Stroke
Stroke is one of main causes of death and impairment worldwide. Objective of this study is to analyze serum High Sensitivity C-Reactive Protein in acute phase stroke in patients attended at Petróleos Mexicanos Hospital Central…
- Conditions
- Stroke, National Institutes of Health Stroke Scale, Serum High Sensitivity C-Reactive Protein
- Trial name
- MAASP (NCT02171858)
- Where
- Mexico
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Hospital Central Sur de Alta Especialidad
Cancer Survivors, Cardiotoxicity
In-Bedroom Renewed Air as Anti-inflammatory Adjuvant Therapy in Cancer Survivors
The BREATHS trial aims to investigate whether overnight in-bedroom air filtration reduces inflammation and cardiac biomarkers in adult survivors of cancer who are at high risk for cardiovascular complications.
- Conditions
- Cancer Survivors, Cardiotoxicity, Cardiovascular Toxicity Induced by Antitumoral Drugs
- Trial name
- BREATHS (NCT06778122)
- Testing
- High efficiency particulate air filtration system (nightly administration), High efficiency particulate air filtration system (nightly and daily administration)
- Where
- 3 sites in Spain
- Volunteers
- 10 people
- Sponsor
- University College, London
Vitamin D, Prematurity
Vitamin D Status and Dose Response in Infants
This study will examine the relationship of serum 25(OH)D levels in infants 32 weeks and greater gestation who are fed infant formula to markers of inflammation and bone metabolism.
- Trial name
- NCT01042561
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Periodontitis (Stage 3), Periodontal Health
Evaluation of the Effect of Smoking on Apelin, Periostin, and High-Sensitivity CRP Levels in Gingival Crevicular Fluid and Serum
Periodontal health is influenced by various local and systemic factors, with smoking being one of the major environmental risk factors.
- Conditions
- Periodontitis (Stage 3), Periodontal Health, Smoking Cigarette
- Trial name
- NCT07870473
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Stable Angina, Positive ETT
Diagnostic Value of HS-CRP in Stable Angina.
The aim of this study was to assess the amount of additive value of HS-CRP levels to a positive exercise tolerance test (ETT) in predicting coronary artery disease (CAD) using coronary angiography as the gold standard.
- Trial name
- NCT00719992
- Testing
- coronary angiography
- Where
- Iran
- Volunteers
- 97 people
- Sponsor
- Shiraz University of Medical Sciences
Rheumatic Diseases
Accuracy of CBC Derived Markers Against CRP and ESR in Detecting Active Rheumatoid Arthritis in Upper Egypt
Rheumatoid arthritis (RA) is a chronic autoimmune disease that leads to persistent synovial inflammation, joint destruction, and disability, often with extra-articular manifestations like interstitial pneumonia.
- Trial name
- NCT07149194
- Testing
- CBC derived markers
- Volunteers
- 150 people
- Sponsor
- Assiut University
Small Bowel Crohn's Disease
Assessment of Capsule Endoscopy Scoring Index (CESI), Harvey-Bradshaw Index (HBI) and Biological Markers in Small Bowel Crohn's Disease (SBCD)
Background: Small bowel Crohn's disease (SBCD) is a chronic relapsing disease, and clinical presentation can vary considerably. Patients are frequently assessed by capsule endoscopy (CE), which enables direct visualization of…
- Trial name
- NCT01555437
- Volunteers
- 58 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Cardiovascular Disease
Clinical Study to Assess High-DHA Fish Oil on Biomarkers of Cardiovascular Disease Risk in Adults on Statin Therapy
The objective of this study is to determine the acute and chronic [4-week] effects of a high-DHA fish oil supplement on fasting and post-prandial (post-meal) biomarkers of cardiovascular disease risk, in adults on Statin therapy.
- Trial name
- NCT01690312
- Testing
- Fish Oil
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- Nutrasource Pharmaceutical and Nutraceutical Services, Inc.
Atherosclerosis, Cardiovascular Disease
A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event
The purpose of this study is to measure the change in high-sensitivity C-reactive protein (hsCRP), a marker of inflammation in the body, with clazakizumab compared with placebo in adults who have elevated hsCRP and at increased…
- Conditions
- Atherosclerosis, Cardiovascular Disease, Obesity, Hypertension
- Trial name
- CLARITY-CRP (NCT07783802)
- Testing
- Clazakizumab
- Where
- 46 sites in United States, Argentina and 2 more
- Volunteers
- 120 people
- Sponsor
- Eli Lilly and Company
Exercise Induced Muscle Damage, Cryotherapy
Acute Cryotherapy on Musculoskeletal Function and Biomarkers
In 2020, Dubois and Esculier proposed a paradigm shift in the acute management of musculoskeletal injuries, advocating for the transition from the traditional PRICE protocol- Protect, Rest, Ice, Compression, Elevation-to the more…
- Trial name
- NCT07211412
- Testing
- Cryotherapy, Eccentric exercise-induced muscle damage
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Texas, El Paso
Infection
Impact of Clinical Guidance & Point-of-care CRP in Children: the ARON Project
Impact of clinical guidance \& point-of-care CRP test in children: the ARON project Trial Design: multicentre, cluster-randomized, parallel group pragmatic trial Trial Participants and setting: Children aged 6 months to 12 years…
- Trial name
- ARON (NCT04470518)
- Testing
- diagnostic algorithm
- Where
- Belgium
- Volunteers
- 6,750 people
- Sponsor
- KU Leuven
Acute Heart Failure
Effect of Short-Term Prednisone Therapy on C-Reactive Protein Change in Emergency Department Patients With Acute Heart Failure and Elevated Inflammatory Markers ( CORTAHF )
Acute heart failure (AHF) is a common discharge diagnosis in the emergency department (ED), associated with 1-month mortality of 6%, and a 30% risk rate of 1-month rehospitalisation.
- Trial name
- CORTAHF (NCT05668676)
- Testing
- Prednisone arm, Usual care
- Where
- France
- Volunteers
- 3 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Coronary Heart Disease, Periodontitis
Changes in the Risk Factors of Coronary Heart Disease Observed After Scaling and Root Planing
The purpose of this study is to determine whether scaling and root planing as a periodontal intervention helps in improving the overall health of patients suffering from coronary heart disease.
- Trial name
- NCT02417376
- Testing
- piezoelectric ultrasonic scaler (frequency of 28-36 KHz), Gracey curettes
- Volunteers
- 70 people
- Sponsor
- Government College of Dentistry, Indore
Coronary Artery Disease
Clopidogrel and Aspirin Together: The Effect on C-Reactive Protein Trial
Inflammation is associated with worsening outcomes among individuals with CAD; C-reactive protein is a well-known marker of inflammation.
- Trial name
- NCT00343876
- Testing
- aspirin, clopidogrel
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Intermountain Health Care, Inc.