Clinical trials: CRP
Chronic Obstructive Pulmonary Disease
Diagnostic Values of C-reactive Protein and Procalcitonin in Predicting Bacterial Infection in Acute Exacerbations of Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease is a serious disease . Exacerbations of Chronic obstructive pulmonary disease is an acute worsening condition of Chronic obstructive pulmonary disease, which always accompanied by clinical…
- Trial name
- NCT03923803
- Testing
- C- reactive protein, Pro calcitonin
- Volunteers
- 90 people
- Sponsor
- Assiut University
COVID-19
Effect Of Calcitriol On Neutrophil To Lymphocytes Ratio And High Sensitivity C-Reactive Protein Covid-19 Patients
This research is a study that compares the administration of calcitriol with the outcomes of COVID-19 patients
- Trial name
- NCT05765617
- Testing
- Calcitriol
- Where
- Indonesia
- Volunteers
- 16 people
- Sponsor
- Universitas Sebelas Maret
STEMI
NLR AND CRP Useful as Cost-Effective Preliminary Prognostic Markers in ST-Elevation Myocardial Infarction
Acute myocardial infarction (AMI) is a serious and fatal cardiovascular emergency and considered the leading cause of mortality worldwide.
- Trial name
- NCT06491667
- Testing
- CBC, C-reactive protein
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Rheumatoid Arthritis (RA)
An Observational Study to Evaluate Impact of CRP-Level on Real World Effectiveness of Upadacitinib as Monotherapy or in Combination With MTX in Adult Participants With Rheumatoid Arthritis
Rheumatoid Arthritis (RA) is a chronic inflammatory disease causing pain, stiffness, swelling and loss of joint function. RA can reduce the ability to perform everyday tasks.
- Trial name
- UPWARDS (NCT04267536)
- Where
- 52 sites in Germany
- Volunteers
- 534 people
- Sponsor
- AbbVie
Anastomotic Leak
Role of Procalcitonin, C-Reactive Protein, and WBC Count in Prediction of Colorectal Anastomotic Leak
The interest in identifying a biological marker for the early detection of AL is growing. Such a marker could play a vital role in modern fast-track multimodal protocols, allowing safe and early discharge of patients after…
- Trial name
- NCT05159024
- Testing
- CRP, PCT, and WBCs trajectories
- Where
- Egypt
- Volunteers
- 205 people
- Sponsor
- Suez Canal University
ST Elevation Myocardial Infarction, C-Reactive Protein
CRP Apheresis in STEMI
Background: In patients with acute ST-elevation myocardial infarction (STEMI), the amount of infarcted myocardium (infarct size) is known to be a major predictor for adverse remodeling and recurrent adverse cardiovascular events.
- Conditions
- ST Elevation Myocardial Infarction, C-Reactive Protein, Apheresis, Myocardial Injury
- Trial name
- NCT04939805
- Testing
- Selective CRP apheresis using the PentraSorb®-CRP system
- Where
- 5 sites in Austria, Germany
- Volunteers
- 202 people
- Sponsor
- Medical University Innsbruck
Tuberculosis, Latent Tuberculosis
TB Screening Improves Preventive Therapy Uptake
HIV-infected people have an increased risk of developing active tuberculosis (TB). To reduce the burden of TB among people living with HIV (PLHIV), the World Health Organization (WHO) recommends systematic TB screening followed…
- Conditions
- Tuberculosis, Latent Tuberculosis, Tuberculosis Prevention, HIV
- Trial name
- TB SCRIPT (NCT04557176)
- Testing
- CRP, point-of-care assay
- Where
- Uganda
- Volunteers
- 1,719 people
- Sponsor
- University of California, San Francisco
Obesity
Glycomacropeptide and Women's Health
This is a study about how a dietary supplement containing a whey protein affects hormones controlling hunger and satiety (leptin and ghrelin) in postmenopausal women with a body mass index between 28 and 35 kg/m2.
- Trial name
- GMP (NCT05551091)
- Testing
- glycomacropeptide (GMP)
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Depressive Disorder, Major
Peripheral Immunomarker Validation in Treatment-resistant Depression
This is a study to characterise the role of inflammatory processes in depression. There is compelling evidence that inflammation is often associated with, and can cause, depression.
- Trial name
- BIODEP (NCT02752178)
- Testing
- MA, DEP
- Where
- 5 sites in United Kingdom
- Volunteers
- 393 people, healthy volunteers welcome
- Sponsor
- University of Cambridge
Cardiovascular Diseases, Atheroma
Periodontal Therapy in Coronary Artery Patients
Gingival inflammation has been associated with cardiovascular diseases, including heart attack and stroke, because of elevation of blood risk markers such as cholesterol, glucose and C reactive protein.
- Conditions
- Cardiovascular Diseases, Atheroma, Coronary Artery Disease
- Trial name
- PerioCardio (NCT01609725)
- Testing
- Subgingival scaling and root planing, Oral prophylaxis
- Where
- Brazil
- Volunteers
- 93 people
- Sponsor
- Federal University of Rio Grande do Sul
Coronary Artery Disease
Clopidogrel and Aspirin Together: The Effect on C-Reactive Protein Trial
Inflammation is associated with worsening outcomes among individuals with CAD; C-reactive protein is a well-known marker of inflammation.
- Trial name
- NCT00343876
- Testing
- aspirin, clopidogrel
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Intermountain Health Care, Inc.
Acute Myocardial Infarction
Interest of COLchicine in the Treatment of Patients With Acute Myocardial INfarction and With Inflammatory Response
Background: Colchicine is an old well-known venerable drug routinely used in gout attacks for instance. More recnetly it is regularly use in the treatment of pericarditis.
- Trial name
- COLIN (NCT02363725)
- Testing
- Colchimax®, Conventional treatment
- Where
- France
- Volunteers
- 44 people
- Sponsor
- University Hospital, Montpellier
Contraception
The Effect of Hormonal Contraceptives on Androgens and Glucose Metabolism
The impact of different administration routes of hormonal contraceptives on androgen secretion, glucose metabolism and inflammation. A prospective randomized trial.
- Trial name
- NCT01087879
- Testing
- Desogestrel-Ethinyl Estradiol contraceptive pill, Etonogestrel-Ethinyl Estradiol vaginal ring, Norelgestromin-Ethinyl Estradiol contraceptive patch
- Where
- Finland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Oulu
Asthma
Levels of Serum Resistin in Asthmatics as a Potential Marker of Systemic Inflammation and Disease State.
The purpose of this study is to determine whether serum resistin levels in asthmatics are elevated. We will recruit subjects from the allergy/immunology clinic with a prior diagnosis of moderate to severe persistent asthma in…
- Trial name
- NCT00339703
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- 59th Medical Wing
Obesity, Diabetes
Calorie Restriction and Changes in Body Composition, Disease, Function, and Quality of Life in Older Adults
The investigators want to determine if the benefits of weight loss outweigh the potential risk in a group of older adults. The investigators will test the hypothesis that changes in diet composition alone or in conjunction with…
- Conditions
- Obesity, Diabetes, Hypertension, Hyperlipidemia
- Trial name
- CROSSROADS (NCT00955903)
- Testing
- Exercise, Reduced Calorie Diet, Weight Maintenance Diet
- Where
- United States
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Cholesterol; Metabolic Disorder, Inflammation
Is Sheep Ghee Cardioprotective?
Normal volunteers were randomly received Sheep ghee or sunflower oil, and before and after the study lipid profile and HS-CRP were measured.
- Trial name
- NCT05492279
- Testing
- sheep ghee, sunflower oil
- Where
- Iran
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Shiraz University of Medical Sciences
Malondialdehyde, Heme Oxygenase
The Effects of Two Anesthetic Drugs on Some Enzyme Levels in Patients Undergoing Lower Extremity Surgery
The primary aim of this study was to compare the effects of dexmedetomidine and ketamine, which are administered intravenously during surgery, on the levels of malondialdehyde, an antioxidant, anti-inflammatory enzyme, heme…
- Conditions
- Malondialdehyde, Heme Oxygenase, C-Reactive Protein
- Trial name
- NCT05950555
- Testing
- Saline, Dexmedetomidine, Ketamine
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ataturk University
Systemic Inflammatory Response Syndrome, Sepsis
Comparison the Value of Several Biomarkers of Sepsis
The purpose of this study is to describe the value of serum sTREM (soluble triggering receptor expressed on myeloid cells)-1, sCD163, procalcitonin (PCT), C-reactive protein (CRP) concentrations, white blood cell (WBC) count and…
- Trial name
- NCT01388725
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Chinese PLA General Hospital
Wearable Devices
Wearable Devices for Early Detection of Postoperative Infection
This systematic review aims to evaluate the efficacy, accuracy, and clinical applicability of wearable infection detection wristbands in postoperative patients across ophthalmology, orthopaedic surgery, and general surgery.
- Trial name
- Wearable Wrist (NCT07334925)
- Testing
- White Blood Cell (WBC), C-reactive Protein (CRP)
- Where
- Egypt
- Volunteers
- 1,284 people
- Sponsor
- Benha University
Sepsis - to Reduce Mortality in the Intensive Care Unit, Burns Involving 20% or More of Body Surface
Evaluating the Accuracy of Multiple Blood Tests to Diagnose Sepsis in Adult Burn Patients
This prospective diagnostic accuracy study evaluates the performance of presepsin and C-reactive protein (CRP) as early biomarkers for suspected sepsis in adult burn patients.
- Trial name
- BioBurnSepsis (NCT07126574)
- Where
- South Korea
- Volunteers
- 165 people
- Sponsor
- Dohern Kym