Clinical trials: CRP
Morbid Obesity, Atherosclerosis
Use of Flaxseed(Alpha Linolenic Acid) Powder in Morbidly Obese Patients With Systemic Inflammation
Preliminary studies have shown that flaxseed powder, rich in the omega-3 alpha-linolenic acid,is beneficial for the general inflammation present in morbidly obese subjects by decreasing elevated serum markers.As omega-3 fatty…
- Conditions
- Morbid Obesity, Atherosclerosis, Systemic Inflammation
- Trial name
- NCT00502021
- Testing
- Alpha-linolenic acid/ALA, Alpha linolenic acid/ALA
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- University of Sao Paulo
Ventilation Therapy; Complications
Correlation Between Muscle Thickness and Inflammation With Ventilator Use in Critically Ill Patients
Decrease thickness of diaphragm muscle, cross-sectional area of rectus femoris and biceps brachii muscle, and increase in CRP would affect ventilator length of use in critically ill patients in ICU
- Trial name
- NCT03933332
- Testing
- Diaphragm thickness, Cross-sectional area of rectus femoris muscle, Cross-sectional area of biceps brachii
- Where
- Indonesia
- Volunteers
- 52 people
- Sponsor
- Universitas Indonesia
Diabetic Retinopathy
Effect of Doxium on High Sensitivity CRP and Endothelin-1 Serum Levels in Patients With Diabetic Retinopathy
Diabetic retinopathy (DR) is a highly specific vascular complication of type 1 and type 2 diabetes mellitus. Calcium dobesilate(CD) or Doxium has been tested in the treatment of diabetic retinopathy showing a slowdown of the…
- Trial name
- NCT01382498
- Testing
- Calcium dobesilate (Doxium)
- Where
- Iran
- Volunteers
- 90 people
- Sponsor
- Tabriz University
Maternal Obesity
Impact of B. Bifidum 900791 Intake on Breast Milk Characteristics of Obese Mothers
Human breast milk harbours a specific microbiota including bacteria from the Lactobacillus and Bifidobacterium genera, that contribute to the bacterial colonization of the infant gut in the post-natal period.
- Trial name
- NCT03913364
- Testing
- Probiotic
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Chile
Coronary Heart Disease, Unstable Angina
Fecal Microbiota and Monocyte Trained Immunity in CHD Patients With Different hsCRP
This single-center study enrolled patients aged 35-75 years who were diagnosed with unstable angina (UA), and had at least one of the three major coronary arteries with a ≥ 50% reduction in lumen diameter by angiographic visual…
- Trial name
- NCT06562309
- Testing
- take feces and blood samples from patients
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Crohn Disease
Significance of Ficolin 2 in the Determination of Serological Activity in Chronic Inflammatory Bowel Disease
Background Determining disease activity in IBD is sometimes difficult and, to be accurate, requires endoscopy. The serum marker CRP has not proven sufficiently valuable as a marker for IBD specific inflammation.
- Trial name
- NCT01473927
- Testing
- Endoscopy
- Where
- 3 sites in Switzerland
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- University of Bern
Rheumatic Arthritis, Rheumatoid Arthritis (RA) Prevention
Efficacy and Safety of Resveratrol in Patients With Rheumatoid Arthritis.
The aim of the current study is to evaluate the effects of resveratrol on the clinical outcome(s) of patients with moderate rheumatoid arthritis. Objectives : 1.
- Conditions
- Rheumatic Arthritis, Rheumatoid Arthritis (RA) Prevention, Inflamation, Antioxidant
- Trial name
- NCT07089381
- Testing
- Resveratrol 1 gm., Methotrexate
- Where
- Egypt
- Volunteers
- 118 people
- Sponsor
- Ain Shams University
Respiratory Tract Diseases
Impact of C-reactive Protein Micromethod Testing in Primary Care on Antibiotics Delivery in Patients With Upper or Lower Respiratory Tract Infections
The project is a pragmatic approach to primary care. The main objective is to evaluate the impact of making a CRP measurement device available in primary care general practices on antibiotic prescribing for upper respiratory…
- Trial name
- ICARE (NCT07632651)
- Testing
- Quick test
- Where
- France
- Volunteers
- 140 people
- Sponsor
- MSPU des 3 Provinces
Diabetes Mellitus, Type 2
Effects of Nateglinide vs Acarbose on Postprandial Glucose Fluctuation, Dyslipidemia, and Inflammatory Factors
This study was conducted to demonstrate superiority of nateglinide in postprandial glucose fluctuation, dyslipidemia, and inflammatory status improvement.
- Trial name
- ENERGY (NCT00928889)
- Testing
- Nateglinide 120 mg, Acarbose 50 mg
- Where
- 6 sites in China
- Volunteers
- 160 people
- Sponsor
- Novartis Pharmaceuticals
Sleep Apnea Syndromes, Inflammation
The Effects of Obesity and Obstructive Sleep Apnea on Inflammation and Heart Disease
Obstructive sleep apnea (OSA) is a serious sleep disorder in which a person's breathing is restricted during sleep. Obese individuals with OSA are at an increased risk of inflammation and heart conditions, but it is unknown…
- Trial name
- NCT00371293
- Testing
- Weight Loss Program, CPAP therapy
- Where
- 2 sites in United States
- Volunteers
- 181 people
- Sponsor
- University of Pennsylvania
Renal Insufficiency
Anti-inflammatory Effect of Atorvastatin on Graft Donor Kidney
Renal Insufficiency is a priority disease in health system, which may require renal replacement therapy based on renal transplantation, which is considered as therapy of choice.
- Trial name
- NCT02355704
- Testing
- Atorvastatin
- Where
- Mexico
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Instituto Mexicano del Seguro Social
Infectious Complications After Colorectal Surgery
Inflammatory Markers After COloRectal Surgery)
The clinical symptoms of septic complications (SC) (responsible for the majority of morbidity in colorectal surgery) become apparent only 5-7 days after the operation, whereas the efficacy of treatment depends on early diagnosis.
- Trial name
- IMACORS (NCT01510314)
- Testing
- C-reactive protein and procalcitonin dosages
- Where
- 3 sites in France
- Volunteers
- 552 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Metabolic Syndrome, Hyperlipidemia
The Effects of ProAlgaZyme on HDL Cholesterol in Individuals With Metabolic Syndrome
The purpose of this study is to determine the effectiveness of ProAlgaZyme in increasing levels of HDL 'good' cholesterol and decreasing total cholesterol and C-reactive protein in patients with Metabolic Syndrome.
- Trial name
- NCT00518960
- Testing
- ProAlgaZyme
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Health Enhancement Products, Inc.
Atrial Fibrillation
Usefulness of Markers to Predict Recurrence of Atrial Fibrillation After Radiofrequency Catheter Ablation
Catheter ablation using radiofrequency is a new therapeutic tool to treat atrial fibrillation with a higher success rate than medical therapy (80% versus less than 50% respectively).
- Trial name
- NCT00315068
- Where
- Switzerland
- Volunteers
- 180 people
- Sponsor
- University Hospital, Geneva
Periodontitis, Periodontitis Stage I
Chlorhexidine and Zinc in Non-Surgical Periodontal Therapy
Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth and is associated with both local tissue destruction and systemic inflammatory responses.
- Conditions
- Periodontitis, Periodontitis Stage I, Periodontitis Stage II
- Trial name
- CHX-Zn (NCT07517991)
- Testing
- Chlorhexidine and zinc application, Scaling and root planing with distilled water
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Ataturk University
ST Elevation Myocardial Infarction (STEMI), Malondialdehyde
Curcumin-Piperine Supplementation in STEMI - SPICE STEMI Trial
This study aims to evaluate whether supplementation with a combination of curcumin and piperine can help reduce inflammation and oxidative stress in patients who have experienced a heart attack called ST-Elevation Myocardial…
- Conditions
- ST Elevation Myocardial Infarction (STEMI), Malondialdehyde, Hs-CRP, Curcumin
- Trial name
- SPICE STEMI (NCT07149961)
- Testing
- Curcumin plus Piperine
- Where
- Indonesia
- Volunteers
- 50 people
- Sponsor
- Universitas Diponegoro
Given Indication for Open Resection of Colorectal Cancer
Diagnostic Value of C-reactive Protein and White Blood Cell Counts for Early Detection of Inflammatory Complications After Open Resection of Colorectal Cancer
Although widely used, there is a lack of evidence concerning diagnostic value of C-reactive protein (CRP) and white blood cell counts (WBC) in the postoperative course.
- Trial name
- NCT01221324
- Volunteers
- 1,200 people
- Sponsor
- Cantonal Hospital of St. Gallen
HIV
Pilot Study of the Effects of Exercise on Aging Among Older Persons With HIV
This pilot study will test the feasibility and acceptability of a 12 week combined aerobic and strength training intervention among persons with HIV who are age 50 or older and do not exercise frequently, and its preliminary…
- Trial name
- SEA (NCT01860261)
- Testing
- Aerobic and Strength Training Intervention
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of California, San Francisco
Saliva
The Effect of Chewing the Tapioca Pearls in Bubble Tea Drinks
Bubble tea drinks contain tea and tapioca pearls. Chewing tapioca pearls in bubble tea drinks may increase salivary components. Because of its proteins, inorganic components, and enzymes, saliva plays an important role in the…
- Trial name
- NCT04670341
- Testing
- chewing tapioca pearls in bubble tea drinks, drink tea without chewing tapioca pearls
- Where
- Indonesia
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Gadjah Mada University
Inflammation on Dialysis, Bacteriuria in Hemodialysis Patients
Clinical Impact of Bacteriuria on Chronic Inflammation in Asymptomatic Hemodialysis Patients
When considering occult infections during the diagnostic workup of inflammation in Hemodialysis (HD) patients, the urine-deprived bladder is frequently dismissed as potential site of infection.
- Trial name
- NCT01570556
- Testing
- Antibiotic treatment
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Assaf-Harofeh Medical Center