Clinical trials: CRP
Juvenile Idiopathic Arthritis
Fibrinogen to Albumin Ratio and C-reactive Protein to Albumin Ratio in Juvenile Idiopathic Arthritis
The fibrinogen to albumin ratio (FAR) and C-reactive protein to albumin ratio (CAR) have emerged as useful biomarkers to predict systemic inflammation.
- Trial name
- NCT06024486
- Testing
- fibrinogen to albumin ratio (AFR) and C-reactive protein to albumin ratio (CAR)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Inflamation, Hemodialysis
Effect of Sertraline on Inflammation in Hemodialysis Patients with Depression: a Randomized Controlled Trial
Depression is a common mental health condition among patients undergoing hemodialysis and is associated with a lower quality of life, poor treatment adherence, and worse overall health outcomes.
- Conditions
- Inflamation, Hemodialysis, End Stage Renal Disease on Hemodialysis (Diagnosis)
- Trial name
- NCT06840379
- Testing
- Sertraline (Oral Antidepressant)
- Where
- Pakistan
- Volunteers
- 62 people
- Sponsor
- Nishtar Medical University
Depression, Inflammation
Tofacitinib in Depression (TIDE)
This study will test whether 7-10 day administration of the anti-inflammatory drug, tofacitinib, has positive effects on people experiencing treatment-resistant depression compared to placebo.
- Trial name
- TIDE (NCT04141904)
- Testing
- Tofacitinib 5 MG [Xeljanz]
- Where
- United Kingdom
- Volunteers
- 2 people
- Sponsor
- University of Oxford
Sepsis
Diagnostic and Prognostic Biomarkers of Sepsis
This study aims to evaluate sepsis biomarkers as soluble triggering receptor expressed on myeloid cells 1 (sTREM-1) and soluble urokinase plasminogen activator receptor (sUPAR) in diagnosis of sepsis in comparison to the…
- Trial name
- NCT04767893
- Where
- Egypt
- Volunteers
- 67 people
- Sponsor
- Sohag University
Suicidal, Suicide Threat
Crisis Response Planning for Military Personnel
The study is a randomized trial comparing outcomes of active duty service members who present to the emergency department at risk for suicide and receive care from providers trained in crisis response planning versus those…
- Conditions
- Suicidal, Suicide Threat, Suicidal Ideation
- Trial name
- ASPIS/CRP (NCT05795764)
- Testing
- Crisis Response Planning, Treatment as Usual
- Where
- United States
- Volunteers
- 700 people
- Sponsor
- United States Naval Medical Center, San Diego
Periodontal Diseases
Comparison of Salivary Biormarkers Levels With Periodontal Clinical Parameters in Smokers and Non-Smokers With Different Periodontal Diseases
To better understand the pathogenesis of chronic inflammatory diseases, the levels of various cytokines are commonly analyzed in tissues and biological fluids collected from the body.
- Trial name
- NCT06459037
- Testing
- Saliva obtaining
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Obstructive Sleep Apnea
Measuring Effectiveness in Sleep Apnea Surgery
The goal of this research is to improve our understanding of the effectiveness of surgical OSA treatment by evaluating its impact on these health-related and functional outcomes and comparing these effects to the changes in…
- Trial name
- NCT00518128
- Testing
- Surgical OSA treatment, Positive Airway Pressure Therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, San Francisco
Chronic Obstructive Pulmonary Disease, COPD
Do Blood Tests Help to Decide Which Patients With Flares of Chronic Obstructive Pulmonary Disease (COPD) Need Antibiotics and Steroids?
The goal of this clinical trial is to see if the use of two simple blood tests: C reactive protein and eosinophils, can reduce the use of steroids and antibiotics in patients with flares of chronic obstructive pulmonary disease…
- Conditions
- Chronic Obstructive Pulmonary Disease, COPD, Exacerbation of COPD, AECOPD
- Trial name
- Bidex (NCT06929767)
- Testing
- biomarker-guided decision making, GOLD recommendations
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Ottawa Hospital Research Institute
Respiratory Distress Syndrome
Comparison of Curosurf and Infasurf in the Treatment of Preterm Infants With Respiratory Distress Syndrome
Premature infants frequently have trouble breathing after birth. If the respiratory disorder is caused by surfactant deficiency or dysfunction, the disease is treated with a medication called surfactant that is given to the…
- Trial name
- NEOSURF (NCT02834624)
- Testing
- Poractant alfa, calfactant
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Missouri-Columbia
Anastomotic Leak, Colorectal Surgery
Early Diagnosis of Anastomotic Leakage After Colorectal Surgery: Italian ColoRectal Anastomotic Leakage Study Group.
Prospective evaluation of early diagnosis of anastomotic leak after colorectal resection through evaluation of Dutch leakage score, serum C-reactive protein and serum Procalcitonin
- Trial name
- iCral (NCT03560180)
- Testing
- Dutch score, Serum C-reactive Protein, serum Procalcitonin
- Where
- 18 sites in Italy
- Volunteers
- 1,131 people
- Sponsor
- Ospedale C & G Mazzoni
Cardiovascular Diseases
Impact of Diet and/or Exercise-induced Weight Loss on Cardiovascular Risk Factors
The purpose of this pilot study is to examine the effect of diet and/or exercise-induced weight loss on nontraditional cardiovascular risk factors such as c-reactive protein, insulin levels and sex steroids in obese…
- Trial name
- NCT00588978
- Testing
- diet and/or exercise
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Yale University
Colorectal Cancer
Inflammation Biomarkers in the Diagnosis of Postoperative Infectious Complications in Colorectal Cancer Surgery
This is a longitudinal, single-center, prospective study to determine the efficiency of WBC Count, CRP, PCT, Neutrophil CD64 and Monocyte Human Leukocyte Antigen- DR in the diagnosis of postoperative infectious complications in…
- Trial name
- NCT03559335
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- State Scientific Centre of Coloproctology, Russian Federation
Hypercholesterolemia With Type2DM
Efficacy and Safety Study of Pitavastatin Compared to atoRvastatin in Type 2 dIabeTes Mellitus With Hypercholesterolemia
A randomized, open label, dose titration study to evaluate the efficacy and safety of Pitavastatin compared to atorvastatin in Type 2 Diabetes Mellitus with hypercholesterolemia
- Trial name
- ESPRIT (NCT00889226)
- Testing
- Pitavastatin, Atorvastatin
- Volunteers
- 161 people
- Sponsor
- JW Pharmaceutical
SIRS, Sepsis
The Value of sTREM-1, PCT, and CRP as Markers for the Detection of Sepsis and Bacteremia Among Patients With a FUO
The investigators enrolled 144 subjects admitted to ICUs: 60 patients with systemic inflammatory response syndrome (SIRS) and 84 patients with sepsis.
- Conditions
- SIRS, Sepsis, Bacteremia
- Trial name
- NCT01410578
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Chinese PLA General Hospital
Risk Factors Cardiovascular Disease, Inflammation
Effects of Exercise With or Without Blueberries on Cardiovascular Risk Markers
About 32 healthy subjects are subjected to 4 weeks of exercise, 4 weeks of washout and 4 weeks of sedentary life style, randomization decides whether they start with exercise or with being "couch potatoes".
- Conditions
- Risk Factors Cardiovascular Disease, Inflammation, Exercise, Sedentary Life
- Trial name
- NCT01274078
- Testing
- Blueberries
- Where
- Sweden
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University Hospital, Linkoeping
Fever, Heart Rate
Urinary Catheter Exchange on Admission of Septic Elderly With Permanent Catheter Before Initiation of Antibiotics
In the era of emerging antibiotics resistant microbiology, we look for better outcome in the treatment of infections in the elderly.
- Conditions
- Fever, Heart Rate, Blood Pressure, C-Reactive Protein
- Trial name
- NCT00503282
- Sponsor
- Shaare Zedek Medical Center
Secondary Hyperparathyroidism, End Stage Renal Disease
A Study to Follow-up Patients With End Stage Renal Disease Undergoing Hemodialysis, Receiving Selective Vitamin D Receptor Activator's for Prevention and Treatment of Secondary Hyperparathyroidism
The aim of this post-marketing observational study is to obtain further data on the long term use, safety and efficacy of selective Vitamin D Receptor Activator's as it is prescribed in the normal clinical setting and according…
- Trial name
- NCT01149291
- Where
- 22 sites in Turkey (Türkiye)
- Volunteers
- 511 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Coronary Artery Disease
Relation Between Lymphocyte-to-C-Reactive Protein Ratio and Coronary Artery Disease Complexity
Aim(s) of the Research : 1. To assess the relationship between the lymphocyte-to-CRP ratio and CAD complexity as assessed by Syntax score in both emergency (STEMI patients undergoing PPCI) and elective settings (patients…
- Trial name
- NCT06958562
- Testing
- No intervention administered. Standard care will be provided. Blood samples for lymphocyte count and CRP will be collected, and Syntax score will be calculated from angiography.
- Volunteers
- 600 people
- Sponsor
- Assiut University
Acute Lymphoblastic Leukemia
Systemic Inflammation Response Index and C-Reactive Protein to Albumin Ratio in Acute Lymphoblastic Leukemia
the goal of this observational study is Assesment of systemic inflammatory index (SII) , system inflammation response index (SIRI) and CRP Albumin ratio(CAR) as biomarkers for ALL prognosis.
- Trial name
- NCT06674850
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Assiut University
Advanced ENT Surgery, Microbiological Flora in the Oropharynx and Lower Airways
Probiotics Against Pathogenic Bacteria in Advanced ENT-Surgery
Surgery in the mouth and oropharynx is performed in an area colonised by bacteria non-pathogenic and pathogenic. Antibiotics are used regularly resulting in disturbances in the intestinal microbiological flora and consequently…
- Trial name
- NCT01730066
- Testing
- L. plantarum 299 and L. plantarum 299v (+maltodextrin)
- Where
- Sweden
- Volunteers
- 45 people
- Sponsor
- Region Skane