Clinical trials: CT Coronary Angiography
Coronary Artery Disease, Atherosclerosis
Sequential Coronary CT-angiography and Biomarkers
Currently, cardiac computed tomography angiography (CCTA) is a well-implemented non-invasive diagnostic imaging modality in patients with stable chest pain.
- Trial name
- PARSEC-NET (NCT02394262)
- Testing
- Coronary CT-angiography, Assesment of biomarkers involved in atherothrombosis
- Where
- Netherlands
- Volunteers
- 140 people
- Sponsor
- Maastricht University Medical Center
Coronary Artery Disease
Role of Cardiac CT in Rapid Access Chest Pain Clinics (RADICAL)
Heart disease remains the most common cause of death in the UK. Chest pain is often the first presenting symptom in patients with heart disease, and may be a warning signal prior to a heart attack or death.
- Trial name
- RADICAL (NCT01464203)
- Testing
- CT coronary angiography, Standard of Care
- Where
- 3 sites in United Kingdom
- Volunteers
- 600 people
- Sponsor
- AJAY YERRAMASU
Coronary Artery Disease
Coronary Computed Tomographic Angiography for Selective Cardiac Catheterization
To determine the effectiveness, safety, and cost efficiency associated with a CCTA-guided selective catheterization strategy for stable patients but without known CAD and an American Heart Association/ American College of…
- Trial name
- CONSERVE (NCT01810198)
- Testing
- Cardiac CT, Invasive Coronary Angiography
- Where
- 13 sites in United States, Brazil and 4 more
- Volunteers
- 1,631 people
- Sponsor
- MDDX LLC
Aortic Valve Stenosis
Multi Modal Cardiac Imaging Prior Transcatheter Aortic Valve Implantation
Transcatheter aortic valve implantation (TAVI) is an emerging alternative therapy for aortic stenosis for patients ineligible for open heart surgery or at high risk for perioperative complications.
- Trial name
- NCT01805739
- Where
- Germany
- Volunteers
- 5,000 people
- Sponsor
- Klinik für Kardiologie, Pneumologie und Angiologie
Coronary Angiography, Coronary Disease
Usefulness of Coronary CT Angiography in Patients With Inconclusive Stress Test Results
The purpose of this study is to evaluate the usefulness of performing a "cat scan" of the heart arteries in patients (without a known history of heart disease) seen by their physician for chest pain.
- Trial name
- IMPACCT (NCT00465335)
- Volunteers
- 200 people
- Sponsor
- Corewell Health East
Acute Coronary Syndromes, Coronary Artery Disease
Computed Tomographic Coronary Angiography for Acute Chest Pain Evaluation
The purpose of this study is to evaluate whether 64-slice Computed Tomographic coronary angiography is useful for rapid diagnosis or exclusion of significant coronary artery disease in patients who present to the Emergency…
- Trial name
- EDCCTA (NCT00615719)
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Virginia Commonwealth University
Coronary Artery Disease
Assessment of Coronary Artery Disease in Stroke Patients
This study is to evaluate the prevalence, plaque characteristics (plaque types, stenosis degree, remodeling) and predictors of coronary atherosclerosis in stroke patients with coronary CT angiography.
- Trial name
- ACADIS (NCT01850693)
- Where
- South Korea
- Volunteers
- 1,657 people
- Sponsor
- Seoul National University Hospital
Chronic Coronary Syndrome, Coronary Disease
SECURE Trial: Stress Echocardiography With Carotid Ultrasound vs Routine CT Coronary Angiography in Chronic Coronary Syndrome for Endpoints
Diseases of the heart and circulation are known as cardiovascular diseases, and they cause over 160,000 deaths each year. Coronary heart disease (CHD) is the most common cardiovascular disease.
- Conditions
- Chronic Coronary Syndrome, Coronary Disease, Coronary Artery Disease
- Trial name
- SECURE (NCT06185530)
- Testing
- Detection of obstructive coronary disease
- Where
- United Kingdom
- Volunteers
- 2,000 people
- Sponsor
- London North West Healthcare NHS Trust
Coronary Artery Disease, Cardiac Disease
Prospective Multicenter Registry On RadiaTion Dose Estimates Of Cardiac CT AngIOgraphy IN Daily Practice in 2017
The "Prospective Multicenter Registry On RadiaTion Dose Estimates Of Cardiac CT AngIOgraphy IN Daily Practice in 2017" (PROTECTION-VI) study is a prospective registry and investigator-initiated initiative without third-party…
- Conditions
- Coronary Artery Disease, Cardiac Disease, Malignancy, Second
- Trial name
- PROTECTION-VI (NCT02996903)
- Where
- 4 sites in United States, Canada and 2 more
- Volunteers
- 4,502 people
- Sponsor
- LMU Klinikum
Coronary Artery Disease, Coronary Artery Stenosis Stent
Deep Learning CAD Screening on Chest CT
Coronary artery disease (CAD) is one of the leading causes of death worldwide. Many people have early atherosclerosis without symptoms, and some may develop significant coronary stenosis before any warning signs appear.
- Trial name
- CAD-AI (NCT07181512)
- Testing
- Deep Learning Analysis of Non-contrast Chest CT
- Where
- 2 sites in China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Yifan Guo
Angina Pectoris
CT Perfusion Added to CT Angiography
Background In the differential diagnosis of unstable angina versus non-anginal chest pain, an exercise test is often the modality of choice for further investigation.
- Trial name
- PERFeCT (NCT02773615)
- Testing
- Cardiac computed tomography
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
CT, Coronary Angiography
Effects of Heart Rates and Variability of Heart Rates on Image Quality of Dual-Source CT Coronary Angiography
The purpose of this study is to investigate the effects of heart rates (including maximum heart rate, average heart rate and minimum heart rate) and variability of heart rate on image quality of DSCT coronary angiography without…
- Trial name
- DSCT (NCT00632918)
- Where
- Taiwan
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Myocardial Ischemia
Comparative Assessment of Coronary MR Angiography Vs Coronary Multislice CT After Coronary Artery Reimplantation in Children and Young Adults.
This is a prospective, multicentric study conducted in order to evaluate if MRI coronarography is as powerful as Cardiac Multislice CT in detection of coronary abnormalities after coronary reimpantation in children over 5 yo…
- Trial name
- IRCADO (NCT02542345)
- Testing
- magnetic resonance imaging
- Where
- France
- Volunteers
- 180 people
- Sponsor
- Centre Chirurgical Marie Lannelongue
Heart Function, Quality of Life
Functional and Clinical Benefits of PCI in Patients With CTO
The purpose of this study is to compare the diagnostic accuracy of hybrid imaging combining CTCA with low-dose stress-only SPECT vs.
- Trial name
- NCT01254253
- Testing
- Percutaneous coronary intervention, PCI
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Xijing Hospital
Type 2 Diabetes, Coronary Artery Disease
Progression of Coronary Atherosclerosis in Asymptomatic Diabetic Subjects
The purpose of the study is to identify a sub-group of diabetic patients at higher risk of progression of coronary disease and also more likely to suffer from heart attack/angina and heart failure.
- Trial name
- PROCEED (NCT02109835)
- Where
- 5 sites in United Kingdom
- Volunteers
- 250 people
- Sponsor
- British Cardiac Research Trust
Coronary Artery Disease, Angina Pectoris
Personalized Risk Evaluation and Diagnosis (Using Corus CAD or ASGES) in the Coronary Tree
The PREDICT study is to develop and validate a diagnostic blood ASGES (age, sex, gene expression score) or Corus CAD for atherosclerotic coronary artery disease (CAD).
- Conditions
- Coronary Artery Disease, Angina Pectoris, Chest Pain, Cardiovascular Diseases
- Trial name
- PREDICT (NCT00500617)
- Testing
- Corus CAD (ASGES)
- Where
- 10 sites in United States
- Volunteers
- 4,350 people
- Sponsor
- CardioDx
Atherosclerosis, Coronary Artery Disease
COroNary CT Angiography Evaluation For Clinical Outcomes: An InteRnational Multicenter Registry (CONFIRM)
The CONFIRM study was developed to examine the prognostic value of cardiac computed tomographic angiography (CCTA) findings for prediction of future adverse cardiac events related to coronary artery disease (CAD) in a large…
- Conditions
- Atherosclerosis, Coronary Artery Disease, Cardiovascular Disease
- Trial name
- CONFIRM (NCT01443637)
- Where
- 20 sites in United States, Austria and 5 more
- Volunteers
- 34,000 people
- Sponsor
- Weill Medical College of Cornell University
Myocardial Perfusion
Assessment of Myocardial Perfusion by Tomography and Scintigraphy in Patients With Cardiac Stress Test With Ischemia
Cardiovascular diseases are important cause of death, and of these have highlighted the Coronary Artery Disease (CAD) and its various clinical manifestations.
- Trial name
- Perfusão (NCT02810106)
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Coronary Artery Disease
Rubidium-82 PET and Tc-99m-MIBI SPET: A Head to Head Comparison
The main purpose of this study is to compare myocardial perfusion imaging using Rubidium-82 PET with Tc-99m-MIBI SPET, in the evaluation of significant Coronary Artery Disease (CAD).
- Trial name
- NCT01379677
- Testing
- Rubidium-82, Sestamibi. reconstitution with sodium pertechnetate (99mTc)
- Where
- United Kingdom
- Volunteers
- 135 people
- Sponsor
- Advanced Accelerator Applications
Coronary Computed Tomography Angiography, Contrast Media
Optimization of Patient Preparation and Imaging Techniques for Cardiac CT
The goal of this clinical trial is to compare four different methods of reducing heart rate before cardiac imaging. The diagnostic imaging technique used in this study is called Computed Tomography (CT) of the coronary vessels…
- Conditions
- Coronary Computed Tomography Angiography, Contrast Media, Cardiac Output
- Trial name
- NCT06879769
- Testing
- Metoprolol I.V., Metoprolol I.V. and 1 hour waiting., Music Intervention, Seloken (Recordati) orally and Metoprolol I.V.
- Where
- Sweden
- Volunteers
- 240 people
- Sponsor
- Karolinska University Hospital