Clinical trials: CTEPH
Pulmonary Embolism, Chronic Thromboembolic Pulmonary Hypertension
Chinese PE Multimodality Imaging Artificial Intelligence Study
The CHinese pulmOnary Embolism Multimodality Imaging-artifiCial intelligencE Study (CHOICE) is a prospective observational multi-center study that will collect imaging text data and raw data of patients with pulmonary embolism…
- Conditions
- Pulmonary Embolism, Chronic Thromboembolic Pulmonary Hypertension, Chronic Thromboembolic Pulmonary Disease
- Trial name
- NCT06526468
- Testing
- Artificial Intelligence
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- China-Japan Friendship Hospital
Pulmonary Hypertension, Pulmonary Arterial Hypertension
Pulmonary Hypertension Biorepository and Registry
Establish a pulmonary hypertension registry and biorepository to lead towards a further understanding of the disease.
- Conditions
- Pulmonary Hypertension, Pulmonary Arterial Hypertension, Pulmonary Hypertension Due to Left Heart Disease, Pulmonary Hypertension, Primary
- Trial name
- PHBR (NCT04808596)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Kansas Medical Center
Pulmonary Hypertension
RUS-registry of PH
Russian National Registry of Patients With Pulmonary Arterial Hypertension (PAH) and Chronic Thromboembolic Pulmonary Hypertension (CTEPH) is a multicenter, observational study of the clinical course and disease management of PAH…
- Trial name
- NCT03707561
- Testing
- Right Heart Catheterization (RHC)
- Volunteers
- 200 people
- Sponsor
- Russian Cardiology Research and Production Center
Hypertension, Pulmonary
Prospective, Non-interventional, Multi-center Post-authorization Safety Study of Riociguat for Chronic Thromboembolic Pulmonary Hypertension (CTEPH )
This local, prospective, non-interventional, multi-center study includes patients treated with Riociguat for inoperable CTEPH(Chronic thromboembolic pulmonary hypertension)/ persistent or recurrent CTEPH after surgical treatment.
- Trial name
- JPMS-CTEPH (NCT02117791)
- Testing
- Riociguat (ADEMPAS, BAY63-2521)
- Where
- Japan
- Volunteers
- 1,298 people
- Sponsor
- Bayer
Pulmonary Hypertension
Bosentan in Patients With Inoperable Chronic Thromboembolic Pulmonary Hypertension (CTEPH)
The present trial investigates the long-term safety, tolerability and efficacy of bosentan in patients with inoperable CTEPH.
- Trial name
- BENEFIT OL (NCT00319111)
- Testing
- bosentan
- Volunteers
- 151 people
- Sponsor
- Actelion
Chronic Thromboembolic Pulmonary Hypertension, CTEPH
New International CTEPH Database
The New International CTEPH Database is a prospective, observational multi-center disease registry run by the International CTEPH Association (ICA), which will collect data in chronic thromboembolic pulmonary hypertension (CTEPH)…
- Trial name
- NCT02656238
- Where
- 38 sites in United States, Australia and 20 more
- Volunteers
- 1,019 people
- Sponsor
- International CTEPH Association
Pulmonary Vascular Disease, Pulmonary Artery Hypertension
HA Residents With PVD, 6MWD Assessed at HA (2840m) vs LA (Sea Level)
To study the effect of relocation from 2840m (Quito) to sea level (Pedernales) in patients with pulmonary vascular diseases (PVD) defined as pulmonary arterial hypertension or chronic thromboembolic pulmonary hypertension (PH)…
- Conditions
- Pulmonary Vascular Disease, Pulmonary Artery Hypertension, Chronic Thromboembolic Pulmonary Hypertension
- Trial name
- NCT05996302
- Testing
- Relocation to sea level
- Where
- Switzerland
- Volunteers
- 24 people
- Sponsor
- University of Zurich
Sleep-Disordered Breathing, Chronic Thromboembolic Pulmonary Hypertension
Impact of Pulmonary Endarterectomy on Sleep-Related Breathing Disorders in CTEPH: The IPES Trial
Pulmonary hypertension (PH) has three main types, pre-capillary PH, post-capillary PH, and combined pre-capillary and post-capillary PH, and it is based on mean pulmonary arterial pressure (PAP) > 20 mmHg measured with a right…
- Conditions
- Sleep-Disordered Breathing, Chronic Thromboembolic Pulmonary Hypertension, Post Operative
- Trial name
- IPES (NCT06060366)
- Testing
- Pulmonary endarterectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Marmara University
Pulmonary Embolism
Pulmonary Embolism: Mechanism and Therapeutic Innovation
To explore the pathogenesis, therapy and outcome of pulmonary embolism (PE) and chronic thromboembolic pulmonary hypertension (CTEPH).
- Trial name
- NCT05360992
- Volunteers
- 1,200 people
- Sponsor
- China National Center for Cardiovascular Diseases
Chronic Thromboembolic Pulmonary Hypertension
Proteomic Pattern Associated With the Diagnosis of Chronic Thromboembolic Pulmonary Hypertension
Chronic ThromboEmbolic Pulmonary Hypertension (CTEPH) is a rare but severe complication of pulmonary embolism (PE). CTEPH is evoked in patients with persistent dyspnea.
- Trial name
- PROTEO-CTEPH (NCT05340023)
- Testing
- blood sample
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Pulmonary Hypertension Outcome Assessment
Zürich Pulmonary Hypertension Outcome Assessment Cohort
PH is a serious disease with a dismal prognosis and impaired quality of life when left untreated. Reliable patient centered and prognostically relevant outcome measures are highly warranted in the field of PH.
- Trial name
- ZHPHCohort (NCT02249806)
- Testing
- PH target therapy according to physician
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University of Zurich
Chronic Thromboembolic Pulmonary Hypertension
Dyspnea in Chronic Thromboembolic Pulmonary Hypertension
Pulmonary embolism, or clots blocking the blood vessels of the lungs, is a common clinical condition requiring treatment with blood thinners. In most patients, recovery is complete.
- Trial name
- NCT03786367
- Where
- Canada
- Volunteers
- 28 people
- Sponsor
- Dr. Denis O'Donnell
Hypertension, Pulmonary, Pulmonary Thromboembolisms
Functional Pulmonary Capillary Surface Area in BPA for CTEPH
Chronic thromboembolic pulmonary hypertension [CTEPH] is caused by pulmonary emboli that have enlarged in pulmonary arteries and have become organized into the vessel wall.
- Trial name
- NCT05719415
- Testing
- Measurement of pulmonary functional capillary surface area
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Jewish General Hospital
Chronic Thromboembolic Pulmonary Hypertension
Cardiac Self-Efficacy in Patients With Chronic Thromboembolic Pulmonary Hypertension
This study aims to analyze the effect of Pulmonary Endarterectomy (PEA) on patients' self-confidence in managing their chronic illness.
- Trial name
- CTEPH3 (NCT07272798)
- Where
- Syria
- Volunteers
- 10 people
- Sponsor
- Damascus University
Sleep-Disordered Breathing, Pulmonary Arterial Hypertension
Sleep Disordered Breathing in Precapillary Pulmonary Hypertension: Effect of CPAP Treatment
Evaluation of the effect of CPAP (continuous positive airway pressure ) treatment in PAH (pulmonary arterial hypertension) and CTEPH (chronic thromboembolic pulmonary hypertension) patients suffering from sleep disordered…
- Conditions
- Sleep-Disordered Breathing, Pulmonary Arterial Hypertension, Chronic Thromboembolic Pulmonary Hypertension
- Trial name
- NCT02583906
- Testing
- CPAP
- Where
- Belgium
- Volunteers
- 8 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Chronic Thromboembolic Pulmonary Hypertension, Residual Pulmonary Hypertension
Continuous Remote Haemodynamic Monitoring With CardioMEMS™ Following Pulmonary Endarterectomy in Chronic Thromboembolic Pulmonary Hypertension:
Chronic thromboembolic pulmonary hypertension (CTEPH) is potentially curable by pulmonary endarterectomy (PEA), although a substantial proportion of patients develop residual pulmonary hypertension despite successful surgery.
- Trial name
- CARDIOMEMSCTPH (NCT07758179)
- Testing
- CardioMEMS
- Volunteers
- 30 people
- Sponsor
- Hospital Universitario 12 de Octubre
Chronic Thromboembolic Pulmonary Hypertension, Pulmonary Embolism
Pulmonary Endarterectomy Guided by CT Scanning for Patients With Chronic Thromboembolic Pulmonary Hypertension----PEACT
This study is a effectiveness study of the application of high-definition enhanced computed-tomography for patients with chronic thromboembolic pulmonary hypertension(CTEPH).The patients with CTEPH was randomized into 2…
- Trial name
- PEACT (NCT03795740)
- Testing
- 3-D CT scanning
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Sheng Liu
Pulmonary Hypertension, Quality of Life
Quality of Life Questionnaire in Pulmonary Hypertension EMPHASIS-10: Brazilian Adaptation and Validation
Pulmonary hypertension (PH) is a severe and heterogeneous condition associated with poor prognosis and significant impairment in quality of life.
- Trial name
- EMPHASIS-10-BR (NCT07822997)
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Pulmonary Hypertension, Chronic Thromboembolic Pulmonary Hypertension
Retrospective Data Analysis of Data From the Zurich PH Registry
The collected data from the Zurich Registry for pulmonary Hypertension (PH) are evaluated in a retrospective analysis. This study examines the number of patients and their exact diagnoses who are treated at the University…
- Conditions
- Pulmonary Hypertension, Chronic Thromboembolic Pulmonary Hypertension, Pulmonary Artery Hypertension
- Trial name
- NCT03198910
- Where
- Switzerland
- Volunteers
- 313 people
- Sponsor
- University of Zurich
Chronic Thromboembolic Pulmonary Hypertension
A Study to Evaluate Efficacy and Safety of Macitentan 75 mg in Inoperable or Persistent/Recurrent Chronic Thromboembolic Pulmonary Hypertension
The purpose of the study is to evaluate the effect of macitentan 75 mg versus placebo on exercise capacity at Week 28 in participants with chronic thromboembolic pulmonary hypertension (CTEPH).
- Trial name
- MACiTEPH (NCT04271475)
- Testing
- Macitentan
- Where
- 168 sites in United States, Argentina and 31 more
- Volunteers
- 127 people
- Sponsor
- Actelion