Clinical trials: CTEPH
CTEPH
OCT Evaluates the Effects of CTEPH Treated by Scoring Balloon
Chronic thromboembolic pulmonary hypertension (CTEPH) is a disease of obstructive pulmonary artery remodelling as a consequence of major vessel thromboembolism.
- Trial name
- NCT05480137
- Testing
- NSE scoring balloon and plain balloon angioplasty
- Where
- China
- Volunteers
- 46 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
CTEPH
Discontinuation Versus Continuation of Riociguat Monotherapy in Chronic Thromboembolic Pulmonary Hypertension Successfully Treated With Balloon Pulmonary Angioplasty
Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare but severe complication of acute pulmonary embolism, characterized by persistent obstruction of the pulmonary arteries by organized thrombi and secondary…
- Trial name
- DIRECTION (NCT07644377)
- Testing
- Discontinuation of riociguat
- Where
- 22 sites in France
- Volunteers
- 150 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pulmonary Arterial Hypertension, Chronic Thromboembolic Pulmonary Hypertension
Prognostic Value of Estimated Plasma Volume in Pulmonary Hypertension
Assessment of the prognostic value of the estimation of plasma volume or its variation in patients with pulmonary arterial hypertension (PAH) or chronic thromboembolic pulmonary hypertension (CTEPH) after acute right heart…
- Conditions
- Pulmonary Arterial Hypertension, Chronic Thromboembolic Pulmonary Hypertension, Acute Right Heart Failure
- Trial name
- NCT05861479
- Volunteers
- 100 people
- Sponsor
- Central Hospital, Nancy, France
Chronic Thromboembolic Pulmonary Hypertension, CTEPH
International BPA Registry
The International Balloon Pulmonary Angioplasty (BPA) Registry is a prospective, multi-center, long-term observational project. Scheduled to start data collection in Q4 2017, the registry will run for approximately four years…
- Trial name
- NCT03245268
- Testing
- Balloon pulmonary angioplasty
- Where
- 18 sites in United States, Austria and 8 more
- Volunteers
- 500 people
- Sponsor
- International CTEPH Association
Chronic Thromboembolic Pulmonary Hypertension
Interventional Treatment of Residual Pulmonary Hypertension in Patients After Pulmonary Thromboendarterectomy
The study evaluates the technique of non-drug treatment of residual pulmonary hypertension in patients with chronic thromboembolic pulmonary hypertension after pulmonary thromboendarterectomy.
- Trial name
- NCT02745106
- Testing
- Radiofrequency pulmonary artery denervation, Ablation catheter, Swan-Ganz catheter for right heart catheterization
- Where
- Russia
- Volunteers
- 50 people
- Sponsor
- Novosibirsk Scientific Research Institute for Circulatory Pathology
Chronic Thromboembolic Pulmonary Hypertension
Identification of Heritable CTEPH
Some patients who have blood clots come down with a life-threatening condition known as Chronic Thromboembolic Pulmonary Hypertension (CTEPH), which is high blood pressure only in the arteries of the lungs.
- Trial name
- NCT03579862
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- Intermountain Health Care, Inc.
Chronic Thromboembolic Pulmonary Hypertension
BPA vs. PEA in CTEPH
Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare and potentially life-threatening progressive disease that evolves from unresolved pulmonary embolism.
- Trial name
- GO-CTEPH (NCT05110066)
- Testing
- Pulmonary endarterectomy, Balloon pulmonary angioplasty
- Where
- 2 sites in Denmark, United Kingdom
- Volunteers
- 139 people
- Sponsor
- University of Aarhus
Chronic Thromboembolic Pulmonary Hypertension, CTEPH
Riociguat in Patients With Operable CTEPH Prior to Pulmonary Endarterectomy (PEA Bridging Study)
This is a randomised, double-blind, placebo-controlled, multicentre, multinational, prospective study in patients with operable chronic thromboembolic pulmonary hypertension (CTEPH) prior to pulmonary endarterectomy (PEA) with…
- Trial name
- NCT03273257
- Testing
- Riociguat, Pulmonary endarterectomy
- Where
- 4 sites in United States, France and 2 more
- Volunteers
- 14 people
- Sponsor
- International CTEPH Association
Cardiovascular Diseases, Venous Thromboembolism
Study on the Clinical Course Of Pulmonary Embolism
The course of both pulmonary embolism (PE) and one of its more relevant late complications, i.e. chronic thromboembolic pulmonary hypertension (CTEPH) is still substantially unknown.
- Conditions
- Cardiovascular Diseases, Venous Thromboembolism, Pulmonary Hypertension
- Trial name
- SCOPE (NCT01781858)
- Volunteers
- 700 people
- Sponsor
- University of Padova
Chronic Thromboembolic Pulmonary Hypertension
3D Echocardiographic Assessment of RV Function in Patients Undergoing Pulmonary Endarterectomy
Chronic thromboembolic pulmonary hypertension causes progressive right heart hypertrophy, dilatation and dysfunction. Surgical treatment is pulmonary endarterectomy, which although only carried out in a single UK centre, provides…
- Trial name
- NCT02426203
- Testing
- Pulmonary endarterectomy
- Volunteers
- 51 people
- Sponsor
- Papworth Hospital NHS Foundation Trust
Myocardial Dysfunction, Endothelial Dysfunction
Bosentan in Myocardium Metabolism and Perfusion Measured by 18F-FDG and 82Rb PET/CT on PAH and CTEPH
The purpose of this study is to assess the effect of bosentan on the myocardial metabolism and the dependent endothelial coronary vasomotoricity in patients presenting a PAH.
- Trial name
- NCT02970851
- Where
- Switzerland
- Volunteers
- 2 people
- Sponsor
- University of Lausanne Hospitals