Clinical trials: Caesarean Delivery
Emergency Cesarean Section, Infection Wound
Single Dose Cefepime Versus Cefuroxime Plus Metronidazole as a Prophylactic Antibiotic During Emergency Intrapartum Cesarean Section
Compare between cefepime versus routine antibiotics as a prophylactic antibiotic during emergency cesarean section in a tertiary center of obstetric care
- Trial name
- NCT04009772
- Testing
- Cefepime, Cefuroxime plus Metronidazole
- Where
- Egypt
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cesarean Section Complications
Clean-CS: A Program to Improve the Safety of C-section
Executive summary: Cesarean delivery, or section (CS), is the single most common surgical procedure performed. Estimates indicate that in low resource settings, CS comprises up to 50% of more of the total volume of operations…
- Trial name
- Clean-CS (NCT04812522)
- Testing
- Clean Cut program
- Where
- 10 sites in Ethiopia
- Volunteers
- 10,506 people, healthy volunteers welcome
- Sponsor
- The Lifebox Foundation
Magnetic Resonance Imaging, Hysteroscopy
Hysteroscopic Evaluation and the Clinical Outcomes of Vaginal Repair of Cesarean Section Scar Defects
Cesarean section scar defects (CSDs) are one of the long-term complications following cesarean section. They can be detected by transvaginal sonography, hysterosalpingography, sonohysterography and magnetic resonance imaging…
- Trial name
- CSD (NCT05858931)
- Testing
- vaginal repair
- Where
- China
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Cesarean Section Complications, Postpartum Hemorrhage
Perioperative Outcomes of Postpartum Hemorrhage in Patients Undergoing Cesarean Delivery
Postpartum haemorrhage is the common cause of maternal death worldwide. The primary purpose of this study is to identify the maternal outcomes after PPH.
- Conditions
- Cesarean Section Complications, Postpartum Hemorrhage, Anesthesia Complication, Blood Transfusion Complication
- Trial name
- NCT04833556
- Where
- Thailand
- Volunteers
- 649 people
- Sponsor
- Mahidol University
Microbial Colonization
Preterm Infant Intestinal Microbiota Development and Maternal Fecal Transplant
The goal of this clinical trial is to study if a oral maternal fecal transplant given to a premature infant born by cesarean section (CS) is safe.
- Trial name
- PREFLOR (NCT06227845)
- Testing
- Fecal microbiota transplant
- Where
- Finland
- Volunteers
- 36 people
- Sponsor
- Otto Helve
Preterm Birth, Preterm Premature Rupture of Membrane
Cerclage After Full Dilatation Caesarean Section
CRAFT-OBS: Observational Study; To evaluate subsequent pregnancy risk of preterm birth in women with a history of previous caesarean in established labour.
- Conditions
- Preterm Birth, Preterm Premature Rupture of Membrane, Preterm Spontaneous Labor With Preterm Delivery
- Trial name
- CRAFT (NCT04110704)
- Testing
- Insertion of transvaginal cerclage
- Where
- United Kingdom
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Cesarean Delivery
Effect of the Uterotonic Carbetocin on Acute Post Cesarean-Section Pain
Carbetocin is an oxytocin agonist used for prevention of postpartum bleeding after cesarean delivery. First studies revealed in 2012 an analgesic effect of carbetocin, compared to its parent substance oxytocin.
- Trial name
- NCT02642263
- Testing
- Carbetocin
- Where
- Switzerland
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Cesarean Delivery
An Observational Study Measuring in a Non-invasive Approach the Nociception Level Index and Its Association With Pain and Anxieiy Perception Evaluated by Questionnaires, in Awake Women During Elective Cesarean Delivery Under Spinal Anesthesiaanxiety
The Nociception Level (NOL) Index is a multiparametric, non-invasive monitor that objectively assesses nociception by integrating several autonomic physiological signals.
- Trial name
- NCT07726316
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Michael Grach
Cardiac Output
The Effect of Ondansetron on Cardiac Output in Elective Cesarean Deliveries
Ondansetron is a medication routinely given to mothers having cesarean deliveries to help prevent and treat nausea and vomiting.
- Trial name
- NCT01841606
- Testing
- Ondansetron, Normal saline
- Where
- Canada
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Wound Infection
A Comparison of Surgical Preparations and Wound Infection Rates for Elective Cesarean Sections
The purpose of this study is to find out if chlorhexidine gluconate solution is better at reducing the rate of wound infection after cesarean section compared to povidone-iodine.
- Trial name
- NCT00528008
- Testing
- povidone-iodine solution, chlorhexidine gluconate
- Where
- Canada
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- Memorial University of Newfoundland
Isthmocele, Cesarean Scar Diverticula
Comparing Decidual Inclusion vs. Exclusion in Uterine Suture Techniques During Cesarean Section to Improve Scar Thickness and Reduce Isthmocele Risk in Primiparous Women
This study compares two ways of closing the uterus during cesarean delivery. In one group, the decidual layer near the uterine cavity is included in the suture. In the other group, this layer is left out.
- Trial name
- DISSUC (NCT07608874)
- Testing
- Single-Layered Non-Locked Closure with Decidual Inclusion, Single-Layered Non-Locked Closure with Decidual Sparing
- Where
- Switzerland
- Volunteers
- 374 people
- Sponsor
- Kantonsspital Baden
Anesthesia, Spinal, Pain
Comparison of Two Analgesic Pretreatment Techniques Before Spinal Needle Insertion for Pain Reduction and Maternal Satisfaction Level Assessment in Women Undergoing LSCS.
Nowadays lower segment cesarean sections are preferably carried out under regional anesthesia due to multiple advantages. Local infiltration of lidocaine or any other anesthetic is used before lumber puncture in many centers to…
- Conditions
- Anesthesia, Spinal, Pain, Pregnancy, Cesarean Section
- Trial name
- NCT04050059
- Testing
- EMLA cream, 2% lidocaine
- Where
- Pakistan
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Anesthesia, Obstetrical
The Effect of Some Parturients' Characteristics on Sensory Block Level After Spinal Anesthesia
Although the exact mechanism remains unknown, the association of pregnancy and decreased local anesthetic requirement is clear. demonstrated that more local anesthetic is required for cesarean section under combined…
- Trial name
- NCT03164096
- Testing
- Bupivacaine Hydrochloride
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Pregnancy
Intravenous Lidocaine and Quality of Recovery After Cesarean Delivery
When given intravenously, the local anesthetic lidocaine has been shown to decrease the amount of pain medication patients require when recovering from several types of surgeries.
- Trial name
- NCT02257346
- Testing
- Lidocaine, Normal Saline
- Where
- United States
- Sponsor
- Northwestern University
Bleeding in Cesarean Section
Efficacy of Compression Sutures in Controlling Excessive Uterine Bleeding During Caesarean Section
The investigators found that B- Lynch suture is more effective than Nausicca suture in controlling excessive uterine bleeding during cesarean section and avoiding the need of hysterectomy.
- Trial name
- NCT05270473
- Testing
- uterine compressive sutures
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams Maternity Hospital
Placenta Accreta, Placenta Previa
Ultrasound in Prediction of Operative Findings in Cesarean Section Among Placenta Accreta Cases
A total of 60 women pregnant more than 28 weeks gestation will be recruited from obstetric outpatient clinic (faculty of medicine -Cairo University Hospital) after being diagnosed of having placenta previa or low lying placenta…
- Trial name
- NCT03286998
- Where
- 2 sites in Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cesarean Delivery Procedures
KIRA Uterine Drain Device Evaluation- First-In- Human Study
The purpose of this research is to evaluate a new investigational medical device, the Kira device, intended to make it easier for the surgical team to monitor blood loss during and immediately after cesarean deliveries…
- Trial name
- RANI (NCT07387380)
- Testing
- Uterine drain for use in cesarean section
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Lucie Medical Inc
Airway Morbidity
Supreme LMA Use in Urgent Caesarean Section
The Supreme Laryngeal Mask Airway (SLMA) is a single use supraglottic device that provides a good seal for positive pressure ventilation and good first attempt insertion rate of 98% in low risk patients undergoing elective…
- Trial name
- NCT02026882
- Testing
- Supreme Laryngeal Mask Airway
- Where
- China
- Volunteers
- 584 people
- Sponsor
- QuanZhou Women and Children's Hospital
Pregnancy Related
Pulmonary Echography and BNP Value Pre- and Post- Elective Cesarean Section in Spinal Anesthesia
Pregnancy is characterized by many biohumoral changes: circulation, respiratory mechanics, oncotic pressure, vascular permeability and many other systems are affected.
- Trial name
- NCT03851679
- Testing
- B-Type natriuretic peptide (BNP) serum values, Pulmonary echography, urine collection
- Volunteers
- 80 people
- Sponsor
- University of Udine
Postoperative Pain, Cesarean Section
Effects of Nerve Blocks on Pain After Caesarean Section and Postpartum Depression
At the end of your cesarean section surgery, which is started by applying medication to the spinal cavity from your waist, pain medication will be applied between the relevant muscle and its covering from your lower abdomen or…
- Conditions
- Postoperative Pain, Cesarean Section, Postpartum Depression
- Trial name
- NCT06221280
- Testing
- Nerve block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
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