Clinical trials: Caesarean Delivery
Anesthesia; Adverse Effect, Cesarean Section Complications
Factors Associated With Failed Spinal Anesthesia for Cesarean Delivery
The aim of this study is to reveal the factor associated with failed spinal anaesthesia in cesarean delivery. We conduct the retrospective case-control study to elucidate the involving factors.
- Trial name
- NCT04685980
- Testing
- spinal anaesthesia with local anaesthetic and intrathecal morphine
- Where
- Thailand
- Volunteers
- 440 people
- Sponsor
- Mahidol University
Post Operative Pain, Caesarean Section
Naldebain® Extended-release Injection After Cesarean Section in Pain Management
Cesarean section is one of the surgeries most commonly leading to postoperative severe acute pain. It was reported that the mean worst pain intensity reached to 6.14 one day after cesarean section in Germany.
- Conditions
- Post Operative Pain, Caesarean Section, Analgesia
- Trial name
- NCT05446311
- Testing
- Dinalbuphine sebacate
- Volunteers
- 20 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Cesarean Section
Postpartum Women's Dexmedetomidine Sedation
Currently, spinal anesthesia is most commonly used for cesarean section.But spinal anesthesia can not block the visceral vagus nerve, and the patients are prone to nausea, vomiting, chest tightness or other discomfort when the…
- Trial name
- NCT02111421
- Testing
- Dexmedetomidine 01, Dexmetomidine 02
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command
Urinary Tract Infections, Cesarean Section; Infection
Caesarean Delivery With or Without an Indwelling Bladder Catheter
The aim of this study is to compare the incidence of catheter associated culture-based urinary tract infection (UTI) after elective CD with or without preoperative placement of a urinary catheter.
- Trial name
- NCT03672214
- Testing
- Without placement of indwelling catheter, With placement of indwelling catheter
- Where
- Denmark
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Postoperative Hypothermia
Prevention of Maternal Hypothermia After Scheduled Caesarean Section Using Active Intravenous Warming
Maternal hypothermia is very frequent after caesarean delivery under spinal anaesthesia and should be prevented, as it induces discomfort and increases the risk of postoperative complications.
- Trial name
- CESAR-RESOL2 (NCT03581721)
- Testing
- enFlow® IV fluid warmer and from July 2019 Fluido®Compact IV fluid warmer
- Where
- France
- Volunteers
- 75 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cesarean Section, Cesarean Delivery
Pain Management After Cesarean Section - A Before-and-After Cohort Study
Inadequate pain relief remains a challenge after Cesarean section (CS) and may significantly impair postoperative recovery. A recent Danish single-center study (n=100) revealed that 66% of elective CS patients experienced severe…
- Conditions
- Cesarean Section, Cesarean Delivery, Pain Management, Pain Management in Postoperative Care
- Trial name
- NCT06813638
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Nordsjaellands Hospital
Labor Pain, Pregnancy
Neuraxial Versus Systemic Analgesia for Latent Phase Labor Effect on Rate of Operative Delivery
The purpose of this study in nulliparous women undergoing induction of labor is to determine whether initiation of neuraxial analgesia compared to systemic opioid analgesia early in labor (< 4 cm cervical dilation)affects the…
- Trial name
- NCT00380978
- Testing
- combined spinal epidural analgesia, late analgesia (systemic)
- Where
- United States
- Volunteers
- 1,026 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Obstetrical Complications From Sedation During Parturition
Transversus Abdominis Plane (TAP) Block for Post Caesarian Pain
Adding TAP block with Bupivacaine may decrease the use of PCA bolus use after caesarean section for pain relief.
- Trial name
- TAPBlock (NCT01986049)
- Testing
- Bupivicaine
- Where
- United States
- Sponsor
- New York Presbyterian Brooklyn Methodist Hospital
Pregnant Women, Enhanced Recovery After Surgery (ERAS) Protocol
ERAS Protocol on Maternal and Fetal Outcomes Following Elective Cesarean Section
The goal of this observational study is to investigate the maternal, fetal, and neonatal outcomes in parturients scheduled to undergo elective cesarean section (CS) receiving either standard care or enhanced recovery after…
- Trial name
- ERAS (NCT06753058)
- Testing
- 25 gram of maltodextrin in 330 mL , Nutricia Fantomalt 4 Gram, Nutri Gıda Ürünleri San. ve Tic. A.Ş., Istanbul, Türkiye, 2 h prior to surgery., Mother baby bonding
- Where
- Turkey (Türkiye)
- Volunteers
- 450 people
- Sponsor
- Gazi University
Scar
Explore the Short- and Mid-term Effects of Fespixon in Scar Cosmesis Following Cervical or Abdominal Surgery
The aim of this study is to evaluate the efficacy of the Fespixon cream for prevention and/or appearance reduction of different types of linear scars during the 12-week treatment phase, which is assessed by the blinded…
- Trial name
- NCT05271708
- Testing
- Fespixon cream
- Where
- Taiwan
- Volunteers
- 46 people
- Sponsor
- National Defense Medical Center, Taiwan
Cesarean Section
Optimal Site of Administration for Continuous Wound Infusion After Cesarean Section
The purpose of this randomized double-blind study is to evaluate in which anatomical layer (AF versus BF) continuous wound infusion of local anesthetics combined with NSAIDs through a multiorifice catheter has the best…
- Trial name
- NCT01160913
- Testing
- Continuous wound infusion, Continuous wound
- Where
- France
- Volunteers
- 56 people
- Sponsor
- Association pour la Recherche et la Formation en Anesthésie Analgésie Réanimation
Cesarean Section, Cicatrix
Fascial Scar Mobilization Techniques in Treating Chronic Caesarian Section Scar Pain
Over 1.37 million Caesarian sections (C-sections) are performed annually in the US . It is estimated that 12-20 % of those will result in chronic scar pain.
- Conditions
- Cesarean Section, Cicatrix, Tissue Adhesions
- Trial name
- NCT02836626
- Testing
- deep fascial mobilization, superficial fascial mobilization
- Where
- 3 sites in United States
- Volunteers
- 29 people
- Sponsor
- Rocky Mountain University of Health Professions
Adverse Effect
Preload Optimization Guided by Inferior Vena Cava Collapsibility Index
The purpose of this study is to investigate the optimal preload guided by inferior vena cava collapsibility index in parturients with prophylactic norepinephrine infusion undergoing cesarean section.
- Trial name
- NCT04272580
- Testing
- Control group, 4 ml/kg group., 8 ml/kg group.
- Where
- China
- Volunteers
- 193 people
- Sponsor
- General Hospital of Ningxia Medical University
Cesarean Section During Labor
Minimum Oxytocin Dose for Cesarean During Labor: Adaptative Clinical Trial
Introduction: postpartum hemorrage is a leading cause of death after cesarean sections in Brazil. Oxytocin is the main drug for both prophylaxis and threatment of postpartum hemorrage because uterine atony is the most prevalent…
- Trial name
- MODCL (NCT02794779)
- Testing
- Oxytocin
- Where
- Brazil
- Volunteers
- 64 people
- Sponsor
- Brasilia University Hospital
Post Operative Pain
The Safety and Efficacy of Surgical Rectus Sheath Block for Postoperative Analgesia After Elective Cesarean Delivery
All participants will receive spinal anaesthesia and will be randomly divided into 2 equal groups. In Group 1, 20 ml of local anesthetic solution will be administered bilaterally to the rectus sheath space under direct vision…
- Trial name
- NCT06020196
- Testing
- surgical rectus sheath block, subdermal local anaesthetic infiltration
- Where
- Egypt
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Ahmed M Maged, MD
Spinal, Hypotension
Prediction of Hypotension Using Perfusion Index Following Spinal Anesthesia in Lower Segment Caesarean Section
Spinal anesthesia for caesarean section is invariably associated with variable degree of hypotension. Hypotension that occurs may be detrimental to various organ system due to inadequate perfusion.
- Conditions
- Spinal, Hypotension, Perfusion Index
- Trial name
- NCT03319433
- Testing
- Perfusion Index
- Volunteers
- 130 people
- Sponsor
- Paropakar Maternity and Women's Hospital
Acute Post-operative Pain Following Caesarean Section
Opioid-free Analgesia for the Management of Acute Post-operative Pain Following Caesarean Section
Background: Multimodal analgesia; a combination of opioid and non-opioid analgesics, for management of acute post-operative pain significantly reduces the incidence of adverse effects associated with liberal post-operative opioid…
- Trial name
- OFAAPPCS (NCT04539249)
- Testing
- Magnesium sulphate, Pentazocine
- Where
- Nigeria
- Volunteers
- 324 people
- Sponsor
- Olakunle Ifeoluwa Makinde
Cicatrix
The Long-term Effect of Perinatal Tissue Mesenchyme Stem Cells in the Treatment for Caesarean Section Scars
The study is to investigate the long-term efficacy of perinatal tissue mesenchyme stem cells treatment on the appearance of a caesarean scar as compared to a similar untreated scar.
- Trial name
- NCT04034615
- Testing
- Mesenchyme Stem Cells low-dose group, Mesenchyme Stem Cells high-dose group
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- Maternal and Child Health Hospital of Foshan
Hypotension, Nausea
Ideal Dose of Phenylephrine to Treat Low Blood Pressure During Cesarean Section
The purpose of this study is to determine the minimum effective bolus dose of phenylephrine to prevent post-spinal hypotension in Cesarean section in 95 % of our patients.
- Trial name
- NCT00379691
- Testing
- phenylephrine
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Surgical Site Infection, Cosmetic Appearance of Cesarean Scar
Prospective Study on Cesarean Wound Outcomes
This study will investigate whether the placement of silver impregnated dressings beginning in the OR will improve wound healing in patients undergoing cesarean delivery compared to traditional Telfa pads.
- Conditions
- Surgical Site Infection, Cosmetic Appearance of Cesarean Scar, Post Operative Pain
- Trial name
- NCT01697748
- Testing
- Silver-impregnated dressing, Telfa pad dressing
- Where
- 3 sites in United States
- Volunteers
- 660 people
- Sponsor
- University of South Florida
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