Clinical trials: Caesarean Delivery
Uterine Scar
Safety of Umbilical Cord Mesenchymal Stem Cell Local Intramuscular Injection for Treatment of Uterine Scars
The purpose of this study is to evaluate the safety of umbilical cord mesenchymal stem cell local intramuscular injection for treatment of uterine scars by a prospective, single-center, open, and single-arm clinical trial.
- Trial name
- NCT03181087
- Testing
- Umbilical cord MSCs
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- Maternal and Child Health Hospital of Foshan
Isthmocele, Uterine Scar Defects
Cesarean Scar Defects After Uterine Closure by Double-layer Barbed or Smooth Suture
Late sequelae of a cesarean section related to a uterine scar defects include gynecological symptoms and obstetric complications.
- Conditions
- Isthmocele, Uterine Scar Defects, Cesarean Section Complications, Uterine Niche
- Trial name
- NCT04825821
- Testing
- Clinical and ultrasonographic assessment
- Where
- Italy
- Volunteers
- 247 people, healthy volunteers welcome
- Sponsor
- Ospedale Policlinico San Martino
Full Term Pregnant Patients, Undergoing Lower Segment Caesarian Section
Comparison of Different Doses of Clonidine to Fentanyl as an Adjuvant to Bupivacaine 0.5% for Spinal Anesthesia
The purpose of this study is to evaluate the safety, quality and duration of block with the addition of Clonidine in different doses to 0.5% heavy bupivacaine, and to compare it with addition of Fentanyl to 0.5% heavy bupivacaine…
- Trial name
- NCT01205204
- Testing
- Fentanyl, Clonidine
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pravara Institute of Medical Sciences University
Hypotension Drug-Induced
Norepinephrine Addition in Spinal Anesthesia of Caesarean Section
The objective is to compare efficacy of prophylactic norepinephrine bolus versus Infusion in prevention of hypotension which occurs frequently after spinal anesthesia for caesarean section.
- Trial name
- NASA (NCT03626454)
- Testing
- Norepinephrine Bolus, Norepinephrine infusion, Normal Saline Flush, 0.9% Injectable Solution
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Fayoum University Hospital
Cesarean Section (MeSH: D002585), Anesthesia, Spinal (MeSH: D000775)
Ultrasound Versus Palpation for Determining Spinal Puncture Level in Cesarean Section
This study compares two methods of identifying the correct intervertebral level before performing spinal anesthesia in women undergoing elective cesarean delivery.
- Conditions
- Cesarean Section (MeSH: D002585), Anesthesia, Spinal (MeSH: D000775), Hypotension (MeSH: D007022)
- Trial name
- USG-SPINE (NCT07789756)
- Testing
- Preprocedural ultrasound level identification, Landmark palpation level identification
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Cesarean Section
Comparison of Barbed and Conventional Sutures in Adhesion Formation Following Cesarean Section
The aim of this randomized controlled trial is to determine whether the use of barbed sutures to close uterine incision at cesarean section is associated with more postoperative adhesions compared with conventional sutures or not.
- Trial name
- NCT03183362
- Testing
- Barbed suture ( STRATAFIX™ ), Conventional suture (VICRYL™)
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Cairo University
Neonatal Respiratory Distress
Vaginal Misoprostol to Improve the Neonatal Respiratory Outcome
Project summary: Objective: To test the hypothesis that administration of vaginal Misoprostol before elective cesarean section will improve the neonatal respiratory outcomes in late preterm and early term neonates through…
- Trial name
- NCT03239327
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 292 people
- Sponsor
- Assiut University
Failed Induction of Labor
Concurrent Oxytocin With Membrane Sweeping Versus Dinoprostone Pessary in Labor Induction of Multiparous Women at Term
The purpose of this study is to compare concurrent oxytocin with membrane sweeping versus dinoprostone pessary in labor induction for multiparas at term with an unfavorable cervix.
- Trial name
- NCT02618096
- Testing
- Oxytocin, Dinoprostone, Membrane sweeping
- Where
- South Korea
- Volunteers
- 154 people
- Sponsor
- Seoul National University Hospital
Comparing Ephedrine With Norepinephrine for Mangement Postspinal Hypotension
Effectiveness of Prophylactic Bolus Ephedrine Versus Norepinephrine for Management of Post Spinal Hypotension
This study was conducted to compare the effectiveness of ephedrine versus norepinephrine for management of hypotension after spinal anesthesia for mothers undergoing elective cesarean section
- Trial name
- NCT05522088
- Where
- Ethiopia
- Volunteers
- 84 people
- Sponsor
- Wachemo University
Obstetric Anaesthesia With Cardiac Complications
A Superior Anesthetic Technique for the Cesarean Section From a Hemodynamic Perspective.
Cesarean section operations are increasing in rates worldwide. A proper anesthetic technique is required to maintain the safety of both the mother and the fetus.
- Trial name
- NCT04989270
- Testing
- General Anesthesia, Regional Anesthesia
- Where
- Oman
- Volunteers
- 2,500 people
- Sponsor
- Sultan Qaboos University
Vitamin K
Maternal and Neonatal Benefits of Prophylactic Administration of Vitamin K Before Elective Cesarean Section
Vitamin K deficiency can cause serious risks to pregnant women and their babies that may lead to hemorrhage, especially in newborns.
- Trial name
- NCT04984083
- Testing
- vitamin k
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Research Centre, Egypt
Adverse Effect
90% Effective Dose of Phenylephrine Infusions Under Intensive and Standard Treatment
The objective of this study is to investigate the 90% effective dose of phenylephrine infusions for preventing postspinal anesthesia hypotension under intensive and standard treatment during cesarean section
- Trial name
- NCT06151522
- Testing
- Alpha-Agonist, α-adrenergic receptor agonist
- Volunteers
- 80 people
- Sponsor
- General Hospital of Ningxia Medical University
Newborn; Hyperthermia
Randomised Controlled Trial on Using Active Warming to Prevent Newborn Hypothermia After Caesarean Delivery
Despite the enormous advantages that skin-to-skin contact (STSC) and Delaying Cord Clamping (DCC) bring, newborns can lose heat quickly if they are not thermally protected.
- Trial name
- NCT06532266
- Testing
- TechTrade Ready Heat Half Body Temperature Management Blankets, Control
- Where
- China
- Volunteers
- 120 people
- Sponsor
- The University of Hong Kong
Therapeutic Touch, Postpartum Period
The Effect of Therapeutic Touch on Pain and Comfort After Cesarean Section
This study was conducted as randomized controlled study to evaluate the effect of Therapeutic Touch on acute pain and comfort level in women who delivered by cesarean section.
- Conditions
- Therapeutic Touch, Postpartum Period, Midwifery, Comfort
- Trial name
- NCT06062160
- Testing
- Therapeutic Touch
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Cesarean Section, Analgesia
IV and Intrathecal Ketamine in Cesarean Section
In the current study, the investigators will compare the effects of low-dose intravenous (i.v.) ketamine versus intrathecal Ketamine added to spinal anesthesia on the time to first request for analgesia and maternal pain scores…
- Trial name
- NCT05679375
- Testing
- Intrathecal ketamine, Intravenous ketamine
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Postoperative Pain
Effect of TAP Block on Time Required for First Analgesic Dose After Cesarean Cection Under Spinal Anesthesia
While opioids are the mainstay for post-operative analgesia after caesarean section, they are associated with various side effects.
- Trial name
- NCT04623632
- Testing
- Transversus abdominus plane block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams Maternity Hospital
Spinal Anesthesia, Pregnancy
Preoperative Shock Indexes and Post-Spinal Hypotension in Cesarean Surgery
This prospective observational study aims to evaluate the predictive performance of preoperative Shock Index (SI) and Modified Shock Index (MSI) for hypotension following spinal anesthesia in elective cesarean surgery.
- Conditions
- Spinal Anesthesia, Pregnancy, Hypotension Postprocedural
- Trial name
- NCT07500519
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Marmara University
Intrahepatic Cholestasis
Induction of Labor in Intrahepatic Cholestasis of Pregnancy
Induction of Labour in Intrahepatic Cholestasis of Pregnancy (ICP) has become a common procedure in management of ICP to avoid fetal complications.
- Trial name
- ILICP (NCT01381939)
- Volunteers
- 5,000 people
- Sponsor
- Karolinska Institutet
Transient Tachypnea of the Newborn, Neonatal Respiratory Distress
Efficacy of Misoprostol in Prevention of Neonatal Respiratory Morbidity in Parturient at Early Term Elective Caesarian Section
Neonatal respiratory morbidities represent a common group of post natal complications including respiratory distress syndrome, transient tachypnea of newborn, and persistent pulmonary hypertension of newborn.
- Trial name
- NCT04780412
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Caesarean Section
The Effect of Presence of Father in the Operating Room on Quality of Recovery of the Parturient
The presence of a partner to support the mother during cesarean and vaginal deliveries is a well-established practice in most countries worldwide.
- Trial name
- NCT07406607
- Testing
- Standard Care (No Partner Presence), Partner Presence in Operating Room
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Karamanoğlu Mehmetbey University
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