Clinical trials: Caffeine-Related Disorders
Myocardial Infarction
Coronary Care Caffeine: Influence of Coffee on Heart Rate Post Myocardial Infarction
Sudden cardiac death due to a heart rhythm disturbance after a heart attack (myocardial infarction) is a common cause of death. It is well documented that sudden cardiac death after a myocardial infarct (MI) is associated with…
- Trial name
- NCT00137098
- Testing
- Caffeine
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- The Royal Bournemouth Hospital
Apnea of Prematurity
Caffeine Citrate to Improve Neonatal Outcomes.
The goal of this clinical trial to learn what dose/s of caffeine citrate works to treat preterm born babies who have episodes where they stop breathing.
- Trial name
- BabyCCINO (NCT06972849)
- Testing
- Caffeine citrate
- Volunteers
- 3,900 people
- Sponsor
- University of Melbourne
Caffeine, Alcohol
Investigating the Effect of Caffeine and Alcohol on Pupil Dynamics
The goal of this study is to understand how caffeine and alcohol affect the ocular and physiological systems, especially how the pupil (the aperture in the colored part of the eye) responds to light.
- Conditions
- Caffeine, Alcohol, Pupillary Response, Eye Movements
- Trial name
- PAC (NCT07625358)
- Testing
- Caffeine administration, Alcohol (Ethanol)
- Where
- Singapore
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Parkinson's Disease
A Drug Interaction Study of KW-6356 With Midazolam, Caffeine, or Rosuvastatin
The purpose of this study is to evaluate the influence of repeated oral doses of KW-6356 on the pharmacokinetics of index substrates for CYP3A4/5, CYP1A2 and BCRP.
- Trial name
- NCT03970798
- Testing
- Midazolam, Caffeine, Rosuvastatin
- Where
- Japan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kyowa Kirin Co., Ltd.
Healthy Volunteer
Determine the Effect of Multiple Doses of AZD7325, CYP Study
To determine the effects of repeated doses of AZD7325 on the pharmacokinetic profile of a CYP3A4 substrate (midazolam and its 1' hydroxy metabolite) and a CYP1A2 substrate (caffeine and its paraxanthine [3-desmethyl] metabolite).
- Trial name
- CYP (NCT00790114)
- Testing
- AZD7325, Midazolam, Caffeine
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
HFrEF - Heart Failure With Reduced Ejection Fraction, HFmrEF
Coffee Use, Physical Activity and Symptomatic Ventricular Arrhythmias in Patients With Left Ventricular Dysfunction and an ICD
The goal of this observational study is to learn whether caffeine consumption is associated with ventricular arrhythmias and physical activity in adults with heart failure, reduced left ventricular ejection fraction, and an…
- Conditions
- HFrEF - Heart Failure With Reduced Ejection Fraction, HFmrEF, Ventricular Arrhythmia, ICD
- Trial name
- CUPS-ICD (NCT07823998)
- Testing
- Questionnaire
- Where
- Belgium
- Volunteers
- 170 people
- Sponsor
- Jean-Benoît Le Polain de Waroux
Caffeine, Sleep
Investigating the Acute and Chronic Effects of a Supplement Containing Caffeine, Vitamins, Minerals and Botanical Extracts on Cognition, Sleep and Wellbeing, in Healthy Volunteers
The aim of the study is to investigate the acute and chronic effects of a supplement containing Caffeine, Vitamins, Minerals and Botanical extracts on cognitive function, sleep and wellbeing, in healthy volunteers.
- Conditions
- Caffeine, Sleep, Cognitive Function, Wellbeing
- Trial name
- NCT06780774
- Testing
- Caffeine, Vitamins, Minerals and Botanical Blend
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Healthy, Elderly
The Effect of Caffeine in Elderly Citizen Following Eight Hour Abstinence From Caffeine Containing Drinks & Foods
The study investigated the effect of caffeine on physical performance in healthy citizens aged over 70 years following eight hours of abstinence from caffeine containing drinks and foods.
- Trial name
- NCT01048515
- Testing
- Caffeine
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Herning Hospital
Healthy
Caffeine Disposition After Inhalation
The purpose of this study is to determine how fast caffeine gets into your body with a product called Aeroshot™. Aeroshot™ is a lipstick sized device that you slide open and then put your mouth over the opening and inhale.
- Trial name
- NCT02184104
- Testing
- Caffeine
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Adolescence, Caffeine
Effects of Caffeine on Sleep-wake Regulation in Teenagers
The aim is to quantify the effects of one dose of caffeine (compared to placebo) on sleep and wakefulness in adolescents.
- Trial name
- NCT04321785
- Testing
- Caffeine
- Where
- Switzerland
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Carolin Reichert
Caffeine, Placebo
Neurophysiological Reserve With Caffeine Manipulation
The objective of this study is to verify if there is a neurophysiologic reserve when caffeine and placebo perceived as caffeine are manipulated in closed- and opened-loop exercises.
- Trial name
- NCT01167478
- Testing
- Caffeine
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Sao Paulo
Dyspnea
Trial of Caffeine to Alleviate Dyspnea Related to Ticagrelor
Ticagrelor treatment is associated with increased rates of dyspnea, where previous studies have implied a possible role of adenosine.
- Trial name
- TROCADERO (NCT02311088)
- Testing
- Caffeine
- Where
- 9 sites in Sweden
- Volunteers
- 26 people
- Sponsor
- Uppsala University
Climbing, Caffeine
Caffeine and Sport Climbing Performance
To determine the effects of ingesting caffeine at a dose of 3 mg/kg body mass on pull-up performance and handgrip-related measures in trained climbers.
- Trial name
- Climbing&CAF (NCT07333443)
- Testing
- Acute and moderate dose of caffeine (3 mg/kg body mass)
- Where
- Spain
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Alcala
Healthy
Effects of Modafinil, Caffeine and Methylphenidate in Healthy Volunteers
In this study the investigators compare three stimulants to each other. The effects of these agents on cognitive performance (eg, attention and memory) and on the brain are being measured.
- Trial name
- MKM (NCT02071615)
- Testing
- Methylphenidate 20 mg tablet given once by mouth, modafinil 200mg tablet given once by mouth, caffein 200mg tablet given once by mouth
- Where
- Germany
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Post Dural Puncture Headache
Caffeine Versus Placebo for Spinal Headaches
Caffeine will be studied against placebo in patients with positional headache after a lumbar puncture (aka "spinal headache").
- Trial name
- NCT00809627
- Testing
- Caffeine, saline
- Where
- United States
- Sponsor
- United States Naval Medical Center, Portsmouth
Aerobic Gymnastics Performance, Sports Performance
Combined Rhodiola Rosea and Caffeine Supplementation for Aerobic Gymnastics Performance
Aerobic gymnastics requires repeated explosive movements, upper-body support elements, and the ability to maintain performance under fatigue.
- Conditions
- Aerobic Gymnastics Performance, Sports Performance, Exercise Recovery, Nutritional Supplementation
- Trial name
- NCT07860242
- Testing
- Rhodiola rosea Supplementation, Caffeine Supplementation, Standardized Aerobic Gymnastics Training
- Where
- China
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Beijing Sport University
Respiratory Distress Syndrome
Caffeine Treatment in in the Delivery Room
Background. In recent years, particular attention has been paid to all interventions that could help reduce the need for mechanical ventilation MV and, therefore, the risk of BPD.
- Trial name
- CAFROOM (NCT04044976)
- Testing
- Caffeine Citrate
- Where
- Italy
- Volunteers
- 42 people
- Sponsor
- University of Florence
Cataract
Prevention of UV- Induced Apoptosis by Caffeine
Investigate if caffeine accumulation in human lens epithelial cells after oral caffeine intake is sufficient to prevent from experimental ultraviolet radiation induced apoptosis
- Trial name
- Caff2 (NCT03534973)
- Testing
- Caffeine intake, No caffeine intake
- Where
- Austria
- Volunteers
- 20 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery