Clinical trials: Cage
Spinal Fusion, Lumbar Fusion
Lumbar Fusion With Porous Versus Non-Porous Cages
The objective of this single site, randomized controlled trial is to assess and compare radiographic and clinical outcomes in patients who are to undergo lumbar interbody fusion procedures (TLIF), supplemented with pedicle screw…
- Conditions
- Spinal Fusion, Lumbar Fusion, Arthrodesis, Spondylolisthesis
- Trial name
- NCT05583864
- Testing
- CONDUIT Porous Titanium Spinal Cage, PROTI 360 Titanium-Coated PEEK Spinal Cage
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Francis Farhadi
Lumbar Spondylolisthesis, Degenerative Lumbar Scoliosis
A Study on the Clinical Use of a New Expandable OLIF Cage With Posterior Bone Grafting in Lumbar Spine Surgery
This clinical trial aims to evaluate the safety and effectiveness of a novel expandable OLIF (Oblique Lateral Interbody Fusion) cage with posterior bone grafting in patients with lumbar degenerative diseases.
- Conditions
- Lumbar Spondylolisthesis, Degenerative Lumbar Scoliosis, Lumbar Disc Herniation, Lumbar Spinal Stenosis
- Trial name
- NCT07028099
- Testing
- Expandable OLIF cage with posterior bone grafting, Conventional OLIF cage
- Volunteers
- 340 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Intensive Care, Invasive Mechanical Ventilation
Lung Recruitment During Chest Physiotherapy in Mechanically Ventilated Patients
In intensive care, respiratory physiotherapy is an integral part of the daily care of patients under invasive mechanical ventilation.
- Conditions
- Intensive Care, Invasive Mechanical Ventilation, Chest Physiotherapy, Airway Clearance
- Trial name
- RECRUTKI (NCT06805357)
- Testing
- Chest Physiotherapy by Rib Cage Compressions (RCC)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Tuberculosis
Cough Audio Classification as a TB Triage Test
TB is the single biggest infectious cause of death (1.5 million died in 2018), killing more HIV-positive people than any other disease, and is arguably the most important poverty-related disease in the world.
- Trial name
- CAGE-TB (NCT05317247)
- Testing
- Cough sounds
- Where
- 2 sites in South Africa, Uganda
- Volunteers
- 1,751 people
- Sponsor
- University of Stellenbosch
Cervical Disc Herniation, Cervical Disc Degeneration
Anterior Cervical Disectomy And Fusion Using The Tritanium® C Anterior Cervical Cage For One Or Two-Levels
This is a prospective, single arm clinical study to evaluate fusion status and patient reported outcomes utilizing the Stryker Tritanium® C Anterior Cervical interbody device at one or two contiguous levels.
- Conditions
- Cervical Disc Herniation, Cervical Disc Degeneration, Degenerative Disc Disease
- Trial name
- Stryker Spine (NCT04214535)
- Testing
- Tritanium C Anterior Cervical Cage
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Corewell Health East
Cervical Cage With Screw, Cervical Degenerative Disc Disease
Screw-Integrated vs Traditional Cervical Cages in ACDF for Degenerative Disc Disease
This study is a prospective, comparative clinical trial conducted at Assiut University Hospitals to evaluate the effectiveness of two different interbody fusion devices in patients with Cervical Degenerative Disc Disease (CDDD).
- Conditions
- Cervical Cage With Screw, Cervical Degenerative Disc Disease, Anterior Cervical Discectomy and Fusion (ACDF)
- Trial name
- NCT07430163
- Testing
- cervical cage with integrated screws, traditional standalone cervical cage
- Volunteers
- 40 people
- Sponsor
- Assiut University
Flexible Flatfoot or Pes Planus
Calcaneal Lengthening Osteotomy With Locking Wedge Plate Versus Synthetic PEEK Cage Interposition for Symptomatic Flexible Pes Planovalgus Foot Deformity in Adolescents
The goal of this interventional study is to compare clinical outcome, radiological parameters, complication rates and time to recovery of calcaneal lengthening osteotomy with locking wedge plate versus PEEK cage interposition in…
- Trial name
- NCT07449650
- Testing
- calcaneal lengthening osteotomy, calcaneal lengthening osteotomy with locking wedge plate, calcaneal lengthening osteotomy with synthetic PEEK cage interposition
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mohamed Elsayed Othman
Humeral Fractures, Proximal
Post-Approval Prospective Study - Conventus CAGE™ PH for Use in Proximal Humerus Fracture Fixation
The purpose of this study is to collect device and procedure experience in everyday clinical practice. The patients are being asked to participate in this study because they are a surgical candidate for the treatment of a broken…
- Trial name
- NCT03489408
- Testing
- Conventus Cage™ PH
- Where
- 5 sites in United States
- Volunteers
- 40 people
- Sponsor
- Conventus Orthopaedics, Inc.
Lumbar Degenerative Disease
CONDUIT vs. PEEK Cages
In this study, the Principal Investigator aim to compare the clinical and radiographic outcomes of patients with degenerative lumbar disease undergoing direct lateral interbody fusion (DLIF) using two different types of lateral…
- Trial name
- NCT06904898
- Testing
- Cougar LS/Syncage ALIF or CONDUIT LLIF/ALIF cage
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Pennsylvania
Disk Herniated Lumbar, Disc Disease Degenerative
Clinical Outcome and Fusion Rate of 3D Printed Interbody Fusion Cages and Titanium Coated PEEK Cages
Prospective, Randomized, Single-Blind Study for the Evaluation of the Clinical Outcome and the Fusion Rate of 3D Printed Interbody Fusion Cages and Titanium Coated PEEK Cages in Transforaminal Lumbar Interbody Fusion
- Conditions
- Disk Herniated Lumbar, Disc Disease Degenerative, Spondylolisthesis
- Trial name
- PRINTLIF (NCT05237908)
- Testing
- Transforaminal Lumbar Interbody Fusion
- Where
- Germany
- Volunteers
- 78 people
- Sponsor
- Aesculap AG
Tibia Vara in Children
Short-term Outcomes of High Tibial Osteotomy Using a Plate Versus a Plate With an Interbody Fusion Cage in Adolescent Tibia Vara : a Comparative Study
Tibia vara is a progressive angular deformity of the lower limb centered at the proximal tibial physis, producing a characteristic bowing of the leg.
- Trial name
- NCT07400705
- Testing
- high tibial osteotomy using interbody fusion cage
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Sohag University
Different Gene Between Different TKIs Effection
Cancer-associated Gene Mutations in CML Treatment With TKIs by NGS
We performed targeted-capture sequencing of 127 known and putative cancer-related genes of patients who best effect to TKIs ,or intolerance to TKIs,or resistance to TKIs by next-generation sequencing (NGS) .
- Trial name
- NCT04274231
- Testing
- different effection
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Cerebral Palsy
Compare The Effectiveness of SCT and PNF In Children With Cerebral Palsy
This study will evaluate the comparative effectiveness of Spider Cage Therapy (SCT) and Proprioceptive Neuromuscular Facilitation (PNF) in managing motor impairments in children with cerebral palsy (CP).
- Trial name
- NCT06851117
- Testing
- Proprioceptive Neuromuscular Facilitation (PNF), Spider Cage Therapy Group, Combined PNF and Spider Cage Therapy Group
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Superior University
Radiculopathy, Cervical
The Norwegian Cervical Arthroplasty Trial
The study will compare cervical arthroplasty with cervical discectomy and fusion, in the treatment of cervical radiculopathy. The 0-hypothesis is that there is no difference between the two methods, when comparing primary and…
- Trial name
- NORCAT (NCT00735176)
- Testing
- Cervical arthroplasty, Anterior cervical discectomy and fusion (ACDF)
- Where
- Norway
- Volunteers
- 136 people
- Sponsor
- Norwegian University of Science and Technology
Cervical Disc Degeneration, Cervical Stenosis
In-house Produced PMMA- Versus PEEK-cages
Subsidence of cervical cages is a common problem. For the study, a new polyacrylmethacrylate cage was designed and prospectively implanted in patients with a mono- or bilevel cervical pathology.
- Trial name
- Palcage (NCT01607775)
- Testing
- Implantation of a PEEK-cage, PMMA-cage
- Volunteers
- 88 people
- Sponsor
- Universitätsmedizin Mannheim
Degenerative Disc Disease (DDD), Spinal Stenosis
PMCF Study on the Effectiveness and Safety of METROSAN Spinal Systems and BONEGRAFT Filling Materials
This is a prospective, multi-center, observational Post-Market Clinical Follow-Up (PMCF) study designed to collect additional safety and clinical performance data on CE-marked Titania® spinal instrumentation and fusion systems…
- Conditions
- Degenerative Disc Disease (DDD), Spinal Stenosis, Spondylolisthesis, Spinal Deformities
- Trial name
- INFO SPINE (NCT07615491)
- Testing
- Titania® Cervical Interbody Fusion Cage (Titanium), Titania® Cervical Interbody Fusion Cage (PEEK), Titania® Posterior Cervical Stabilization System
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 561 people
- Sponsor
- Metrosan End. ve Elk. Mek. Cihazlar ve Tibbi Malz. San. Tic. Ltd. Co.
Chronic Respiratory Failure
Ambulatory Adaptation to Non-Invasive Mechanical Ventilation
A randomised study to assess the effectiveness of ambulatory adaptation to non-invasive mechanical ventilation in patient with hypercapnic respiratory failure secondary to neuromuscular diseases or alterations in thoracic cage in…
- Trial name
- NCT00698958
- Testing
- Ambulatory adaptation to non- invasive mechanical ventilation for 7 days, Hospital based adaptation to non- invasive mechanical ventilation for 7 days
- Volunteers
- 52 people
- Sponsor
- Hospital Clinic of Barcelona
Degenerative Disc Disease Lumbar
FLXfit Post Market Outcome Study Protocol
This investigation will provide safety and effectiveness information on the use of the FLXfit™ Cage. Data will be used for Post Market follow-up of the FLXfit™ system by evaluating: Safety as measured by the rate of serious…
- Trial name
- TLIF (NCT02882243)
- Testing
- FLXfit Cage for fusion
- Volunteers
- 40 people
- Sponsor
- Foundation for Orthopaedic Research and Education
Atlantoaxial Dislocation
Clinical Application of a Self Stabilizing Atlantoaxial Fusion Cage
Conventional open surgery often requires extensive dissection of the muscle insertion points of the suboccipital muscle group during the insertion position and direction of the atlas axis screw, resulting in sustained…
- Trial name
- NCT05876611
- Testing
- New type of self stabilizing atlantoaxial fusion cage
- Volunteers
- 400 people
- Sponsor
- Peking University Third Hospital
Healthy
Manual Diaphragm Release Technique Effects On Tidal Volume in Elderly
Question: Does manual diaphragm release change kinematics and respiratory function of elderly subjects? Design: Randomized controlled trial with concealed allocation and double-blinding.
- Trial name
- NCT01975740
- Testing
- The manual diaphragm release technique
- Where
- Brazil
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco