Clinical trials: Calcinosis
Styloid-Stylohoid Syndrome, Temporomandibular Disorder
Evaluation of Styloid Chain Calcification to the Patient With the Temporomandibular Joint Disorder
The aim of the study was to evaluate any relation between elongated styloid process (ESP) and type of Temporomandibular Joint Disorders (TMD).
- Trial name
- NCT04280107
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people
- Sponsor
- Nuh Naci Yazgan University
Percutaneous Coronary Intervention, Coronary Artery Calcification
Balloon Lithoplasty for Preparation of Severely Calcified Coronary Lesions
Severely calcified coronary stenoses are difficult to treat with percutaneous coronary intervention (PCI) using current techniques and there is little specific evidence on how to best treat these cases.
- Conditions
- Percutaneous Coronary Intervention, Coronary Artery Calcification, Coronary Artery Disease
- Trial name
- BALI (NCT04253171)
- Testing
- Lithoplasty, Conventional
- Where
- 9 sites in Belgium, Denmark and 2 more
- Volunteers
- 200 people
- Sponsor
- Herlev and Gentofte Hospital
Aortic Regurgitation, Aortic Disease
Prospective Multicenter Study Evaluating Myval TAVR Safety and Effectiveness in High-risk Severe AR
Prospective study is designed to evaluate the safety and efficacy of Myval THV series in patients with severe symptomatic non- or mild-calcified aortic regurgitation.
- Conditions
- Aortic Regurgitation, Aortic Disease, Calcified Aortic Valve
- Trial name
- MARVELTAVI (NCT07751965)
- Testing
- Myval THV series
- Volunteers
- 164 people
- Sponsor
- Ceric Sàrl
Vascular Calcification
Aortic Calcification and Vitamin K Antagonists
The vitamin K antagonists (VKA) are necessary drugs of prevention and treatment of thrombo-embolic disease. The AVKAL study assesses the impact of VKA treatment on the aortic calcifications development.
- Trial name
- AVKAL (NCT02823093)
- Where
- France
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Adenine Phosphoribosyltransferase Deficiency, AH Amyloidosis
National Registry of Rare Kidney Diseases
The goal of this National Registry is to is to collect information from patients with rare kidney diseases, so that it that can be used for research.
- Conditions
- Adenine Phosphoribosyltransferase Deficiency, AH Amyloidosis, AHL Amyloidosis, AL Amyloidosis
- Trial name
- RaDaR (NCT06065852)
- Where
- United Kingdom
- Volunteers
- 35,000 people
- Sponsor
- UK Kidney Association
Secondary Hyperparathyroidism, Chronic Kidney Disease
Study to Assess Patient Management Practices and Quality of Life With Paricalcitol Capsules in the Treatment of Secondary Hyperparathyroidism in Stage 3-5 Chronic Kidney Disease Patients Not Yet on Dialysis
Paricalcitol capsules (Zemplar®) received marketing authorization in Sweden in late 2007 for the prevention and treatment of secondary hyperparathyroidism in patients with Stage 3 \& 4 Chronic Kidney Disease (CKD).
- Trial name
- CAPITOL (NCT01265992)
- Where
- 10 sites in Sweden
- Volunteers
- 50 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Healthy
The Efficacy of Vitamin K2 n Human Osteoporosis, Blood-vessel Calcification and Sclerosis
This study used the generally recognized as safe (GRAS) grade of Bacillus subtilis natto to produce Vitamin K2, Menaquinone-7(MK-7), via fermentation, for functional evaluation.
- Trial name
- NCT01928134
- Testing
- Vit K2+ Vit D3+ calcium carbonate (CaCO3), Vit K2+CaCO3
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Changhua Christian Hospital
Aggression, Intellectual Disability
Reducing Aggression Among People With an Intellectual Disability
The study is an randomised controlled trial (RCT) to test whether supplementation of vitamins, minerals and n-3 fatty acids may reduce aggressive behavior in people with intellectual disabilities.
- Trial name
- PSYVB (NCT03212092)
- Testing
- Multivitamin, mineral & n-3 FA
- Where
- 7 sites in Netherlands
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Hemodialysis, Hyperphosphatemia
Outcome Study of Lanthanum Carbonate Compared With Calcium Carbonate in Hemodialysis Patients : Landmark Study
The purpose of this study is to demonstrate decrease in cardiovascular mortality and morbidity in Japanese hemodialysis patients treated with Lanthanum carbonate compared with those with Calcium carbonate.
- Trial name
- LANDMARK (NCT01578200)
- Testing
- Lanthanum Carbonate, Calcium Carbonate
- Where
- Japan
- Volunteers
- 2,309 people
- Sponsor
- Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan
Nephrocalcinosis
Epidemiology and Risk Factors of Nephrolithiasis and Nephrocalcinosis With Pediatric Onset
The aim of the study is to build a database of pediatric patients affected by nephrolithiasis or nephrocalcinosis in order to investigate their clinical and epidemiological characteristics.
- Trial name
- Calcolosi-kid (NCT07874087)
- Where
- Italy
- Volunteers
- 800 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Mitral Annular Calcification
Surgical Implantation of TRAnscatheter vaLve in Native Mitral Annular Calcification (SITRAL) Study
The purpose of this study is to establish the safety and feasibility of the Edwards SAPIEN 3 valve in subjects with mitral annular calcification (MAC) associated with mitral stenosis (MS) and/or mitral regurgitation who are at…
- Trial name
- SITRAL (NCT02830204)
- Testing
- Mitral Valve Replacement (MVR) with Sapien3
- Where
- 6 sites in United States
- Volunteers
- 25 people
- Sponsor
- Baylor Research Institute
Coronary Artery Calcification, Metabolic Syndrome
High-intensity Statin and Ezetimibe Therapy for Asymptomatic Patients With Positive Coronary Calcium
The aim of this study is to compare safety and efficacy between the aggressive treatment with combination of high-intensity statin and ezetimibe and the current standard lipid lowering treatment in asymptomatic patients with…
- Conditions
- Coronary Artery Calcification, Metabolic Syndrome, Dyslipidemias
- Trial name
- DECISION-CAL (NCT05845424)
- Testing
- Guideline directed statin therapy, High intensity statin plus ezetimibe therapy
- Where
- South Korea
- Volunteers
- 6,000 people
- Sponsor
- Samsung Medical Center
Sodium Thiosulfate, Ectopic Ossification
Treatment of Ectopic Calcification / Ossification With Sodium Thiosulfate (CATSSO)
Ectopic calcification and ossification complicate many diseases, which are rare for the most part. These calcifications (or ossifications) are generally classified according to their apparent formation mechanism.
- Trial name
- NCT03979378
- Where
- 7 sites in France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Limoges
Bone Diseases, Endocrine, Nutritional and Metabolic Diseases
Gut Microbiome Mediated Effects of Inulin Supplementation on Mineral and Bone Metabolism in Hemodialysis Patients
The overall objective of the study is to examine the changes within the gut microbiome after the supplementation of inulin and its effect on markers of mineral metabolism and bone turnover.
- Trial name
- NCT02718885
- Testing
- Inulin, Maltodextrin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Illinois at Urbana-Champaign
ASCVD, Coronary Artery Calcification
Notification of Incidental Coronary Artery Calcium in Patients With Atherosclerotic Cardiovascular Disease (NOTIFY-ASCVD)
Estimate the impact of notifying both patients and their clinicians of the presence of incidental coronary artery calcium (CAC) on initiation of lipid-lowering therapy in patients with ASCVD who are not receiving lipid-lowering…
- Trial name
- NOTIFY-ASCVD (NCT05858879)
- Testing
- Notification of patients and clinicians
- Where
- United States
- Volunteers
- 233 people
- Sponsor
- Stanford University
Vascular Calcification
Oral Alfacalcidol and Coronary Artery Calcification in Predialysis Chronic Kidney Disease
Active vitamin D at therapeutic dose may prevent vascular calcification but in supraphysiologic dose may precipitate it.
- Trial name
- NCT01364688
- Testing
- oral alfacalcidol, no drug
- Where
- Thailand
- Volunteers
- 80 people
- Sponsor
- Ramathibodi Hospital
Type 2 Diabetes, Vascular Calcification
Coronary Artery Calcification in Type 2 Diabetes Mellitus (USCAC Study)
Coronary artery calcification (CAC) is a common complication of type 2 diabetes mellitus(T2DM), which can significantly increase all-cause mortality and the incidence of serious cardiovascular events, and increase the burden of…
- Conditions
- Type 2 Diabetes, Vascular Calcification, Coronary Artery Calcification, Strains
- Trial name
- NCT04889053
- Where
- China
- Volunteers
- 1,400 people
- Sponsor
- University of South China
Calciphylaxis
Calciphylaxis : Population, Risk Factors, Diagnostic Practice, Therapeutic and Outcome
Calciphylaxis, also called Calcific Uremic Arteriolopathy (CUA) is a lethal affection mostly affecting patient in end stage renal disease. The survival rate is described around 20 to 46% at one year.
- Trial name
- CalciWest (NCT02854046)
- Testing
- Calcific Uremic Arteriolopathy
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Nantes University Hospital
Atherosclerosis, Atheroscleroses, Coronary
Detection of Coronary Artery Calcifications by Whole Blood Transcriptome Analyzed by Artificial InTelligence Algorithms
The goal of this observational study is to determine the diagnostic accuracy of peripheral whole blood transcriptomes analyzed by an artificial intelligence algorithm to detect the presence and extent of coronary calcification in…
- Conditions
- Atherosclerosis, Atheroscleroses, Coronary, Atherosclerotic Plaque
- Trial name
- CAC-TRAIT (NCT05619042)
- Where
- Argentina
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Santiago Gabriel Miriuka
Vascular Calcification
Effect of Phosphorus on Valvular and Vascular Calcification in ESRD
Evaluation of the calcifying effect of phosphorus on vascular smooth muscle and detect the association between serum phosphorus and valvular and vascular calcification in end stage renal disease patients
- Trial name
- NCT03360331
- Volunteers
- 30 people
- Sponsor
- Assiut University