Clinical trials: Calcium Pyrophosphate Deposition Disease
Rotator Cuff Tear Arthropathy
Does Botulinum A Toxin Help With Pain From Rotator Cuff Arthropathy?
Rotator cuff arthropathy is a cause of shoulder arthritis which is a common condition seen both in primary and secondary care. It is a painful condition, with significant disability.
- Trial name
- NCT02512536
- Testing
- Botulinum Toxin Type A
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
Rotator Cuff Tear Arthropathy, Post Operative Pain
Effect of Radiofrequency of Suprascapular Nerve in Shoulder Reverse Arthroplasty
The purpuse of this study is to asses if the pulsed radiofrecuency of the supraescapular nerve and accesory nerve have the same or superior efectivity controlling the acute postoperative pain than interscalenic braquial plexus…
- Trial name
- NCT05785572
- Testing
- supraescapular nerve radiofrequency, interescalenic braquial plexus
- Where
- Spain
- Volunteers
- 54 people
- Sponsor
- Hospital Universitario Virgen Macarena
Gitelman Syndrome, CPPD - Calcium Pyrophosphate Deposition Disease
The Osteoarticular Manifestations in Patients With Gitelman Syndrome
Patients with clinically and genetically confirmed Gitelman Syndrome are screened for CPPD, and the clinical and radiographic manifestations are collected and analyzed.
- Trial name
- CPPD and more (NCT06922370)
- Testing
- conventional radiograph or computed tomography
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Rotator Cuff Tear Arthropathy, Osteo Arthritis Shoulders
Clinical Study Evaluating Outcomes of Reverse Shoulder Arthroplasty With SMR Stemless
The objectives of this study are the assessment of the clinical, radiographical and patient-reported outcomes of SMR Stemless Reverse Shoulder Arthroplasty (LimaCorporate S.p.A.) used as standard of care over a period of at least…
- Trial name
- SSPR (NCT04529798)
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Arthro Medics AG
Gout, Chondrocalcinosis
CRYSTALILLE Cohort: Getting the Whole Picture of Crystal-related Arthropathies
The objective of this research is to collect data to create an observatory of microcrystalline rheumatism (gout and calcium-crystal rheumatism) in patients treated at the Groupement des Hôpitaux de l'Institut Catholique de Lille…
- Conditions
- Gout, Chondrocalcinosis, Hydroxyapatite
- Trial name
- CRYSTALILLE (NCT04695028)
- Testing
- Data collection
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Lille Catholic University
Calcium Pyrophosphate Deposition Disease, Rheumatic Diseases
Calcium Pyrophosphate Deposition (CPPD) Disease
The goal of this clinical trial is to describe the transcriptomic and metabolomic profile of patients with chronic Calcium Pyrophosphate Deposition (CPPD) compared to those with acute CPPD.
- Trial name
- PYC-OMIC (NCT07005804)
- Testing
- transcriptomic and metabolomic analysis
- Where
- France
- Volunteers
- 137 people
- Sponsor
- Lille Catholic University
Calcific Tendinitis of Shoulder
A Novel Classification in Calcific Tendinitis of the Shoulder: Evaluating MRI Localization and Related Treatment Strategies
Calcific tendinitis of the shoulder is among the frequently encountered shoulder problems. Conservative treatment is often preferred for its management.
- Trial name
- NCT07409818
- Testing
- Conservative non-surgical treatment, Debridement, Side to side repair
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people
- Sponsor
- Koç University
CPPD - Calcium Pyrophosphate Deposition Disease
Colchicine to Reduce Your SympToms And Lower Levels of Inflammation, Zeroing in on Effective CPPD Disease Treatment
The goal of this clinical trial is to learn if colchicine reduces levels of proteins indicating inflammation in the blood in individuals with calcium pyrophosphate deposition (CPPD) disease.
- Trial name
- CRYSTALLIZE (NCT06855433)
- Testing
- Colchicine Pill
- Where
- 5 sites in United States
- Volunteers
- 150 people
- Sponsor
- Brigham and Women's Hospital
Rotator Cuff Tear Arthropathy
Impact of Humeral Component Version on Outcomes Following RTSA
The proposed study is a prospective, single-blinded, randomized trial to investigate the impact of humeral component version on shoulder range of motion and patient reported functional outcomes following reverse total shoulder…
- Trial name
- NCT03111147
- Testing
- 0 degrees humeral component version, 30 degrees humeral component retroversion
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Corewell Health East
Shoulder Pain, Osteoarthritis of Glenohumeral Joint
Functional and Radiographic Outcomes After Shoulder Surgery
The objective of this study is twofold: First, to determine whether higher levels of pre-operative psychological distress predict worse outcomes after arthroscopic rotator cuff repair; second, to obtain functional outcomes (VAS…
- Conditions
- Shoulder Pain, Osteoarthritis of Glenohumeral Joint, Rotator Cuff Tear Arthropathy
- Trial name
- NCT01405781
- Where
- 2 sites in United States
- Volunteers
- 1,034 people
- Sponsor
- University of Utah
Osteoarthritis Shoulder, Avascular Necrosis
Perform Humeral System Study
This study is an international, single arm, multicenter, prospective, non-significant risk, Post-Market Clinical Follow-up study, which is designed to collect safety and performance data at baseline, surgery, immediate post-op…
- Conditions
- Osteoarthritis Shoulder, Avascular Necrosis, Post-traumatic Arthrosis of Other Joints, Shoulder Region, Rotator Cuff Tear Arthropathy
- Trial name
- PHS (NCT05067543)
- Testing
- Tornier Perform Humeral - Stem
- Where
- 11 sites in United States, Canada and 3 more
- Volunteers
- 300 people
- Sponsor
- Stryker Trauma and Extremities
Rotator Cuff Tear Arthropathy, Rotator Cuff Tear
Abduction Brace Versus Antirotation Sling for Immobilization Following Reverse Shoulder Arthroplasty and Rotator Cuff Repair
To compare the functional and anatomical outcomes, and patient satisfaction and compliance between two different postoperative immobilization methods - abduction shoulder brace versus simple arm sling - following 2 common…
- Trial name
- NCT03488433
- Testing
- Abduction brace, Antirotation sling
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Chondrocalcinosis
Trial of Colchicine Versus Prednisone for the Treatment of Acute CPPD Arthritis
Chondrocalcinosis, recently renamed the calcium pyrophosphate deposition (CPPD) disease, is a very frequent affection of the elderly and causes very painful arthritis.
- Trial name
- COLCHICORT (NCT03128905)
- Testing
- Colchicine opocalcium 1mg, Prednisone : Cortancyl 20mg
- Where
- 7 sites in France
- Volunteers
- 111 people
- Sponsor
- Lille Catholic University
Calcific Tendinitis, Calcific Tendinitis of Shoulder
Comparison of the Efficiency of Ultrasound-Guided Lavage and Subacromial Bursa Injection in Calcific Tendinitis
It is aimed to compare in the early period the clinical and ultrasonographic findings in terms of the effectiveness of ultrasound-guided subacromial bursa injection with corticosteroid and ultrasound-guided lavage, which are the…
- Conditions
- Calcific Tendinitis, Calcific Tendinitis of Shoulder, Shoulder Pain
- Trial name
- NCT05272085
- Testing
- Ultrasound Guided Lavage, Ultrasound Guided Subacromial Bursa Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Istanbul University - Cerrahpasa
Rheumatoid Arthritis, Osteoarthritis
Regulatory B Cells in Inflammatory Rheumatisms and Biomarkers of Response to Biologic Treatments
B cells are known to play an important role in auto-immune diseases by activating T cells, secreting inflammatory cytokines and autoreactive antibodies.
- Conditions
- Rheumatoid Arthritis, Osteoarthritis, Systemic Lupus Erythematosus, Sjogren's Syndrome
- Trial name
- NCT01642706
- Where
- France
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Rotator Cuff Arthropathy
Prosthesis Versus Active Exercise Program in Patients With Rotator Cuff Arthropathy
Reverse shoulder arthroplasty (RSA) is a well-established treatment for rotator cuff arthropathy. However, the effectiveness of RSA has not been compared to non-surgical treatment in a randomised controlled trial.
- Trial name
- REACT (NCT04864158)
- Testing
- TSA-group, Exercise-group
- Where
- 8 sites in Denmark, Estonia and 2 more
- Volunteers
- 102 people
- Sponsor
- University of Aarhus
Primary Osteoarthritis, Secondary Osteoarthritis
SMR Stemless Shoulder Arthroplasty Clinical Study
Shoulder arthroplasty is a reliable procedure for the treatment of severe shoulder joint diseases to relieve pain and restore shoulder function.
- Conditions
- Primary Osteoarthritis, Secondary Osteoarthritis, Post-traumatic; Arthrosis, Rheumatoid Arthritis
- Trial name
- NCT02679352
- Testing
- SMR Stemless
- Where
- 4 sites in Germany, Netherlands and 1 more
- Volunteers
- 78 people
- Sponsor
- Limacorporate S.p.a
Primary Osteoarthritis, Secondary Osteoarthritis
Clinical and Radiological Outcomes of Medacta Shoulder System (BE)
This is a post-market surveillance study on Medacta Shoulder System
- Conditions
- Primary Osteoarthritis, Secondary Osteoarthritis, Rotator Cuff Tear Arthropathy, Rheumatoid Arthritis Shoulder
- Trial name
- NCT05002335
- Testing
- Medacta Shoulder System
- Where
- 3 sites in Belgium
- Volunteers
- 200 people
- Sponsor
- Medacta International SA
Osteoarthritis of the Shoulder, Avascular Necrosis
Database Retrieval for the Comprehensive Shoulder
This study is a retrieval of database information regarding survivorship of the Comprehensive Shoulder System family of products.
- Conditions
- Osteoarthritis of the Shoulder, Avascular Necrosis, Rheumatoid Arthritis, Prior Failed Revision
- Trial name
- NCT03409718
- Testing
- Biomet Comprehensive Shoulder System
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Zimmer Biomet
Rotator Cuff Tear Arthropathy, Spine Degeneration
Cutibacterium Acnes in Deep Tissues in Primary Spine and Shoulder Surgery
Obtain deep tissue samples from patients undergoing primary prosthetic surgery of the shoulder and patients undergoing primary instrumented surgery of the spine.
- Trial name
- NCT05355844
- Testing
- Benzoyl peroxide
- Volunteers
- 200 people
- Sponsor
- Hospital del Mar