Clinical trials: Calculi, Renal
Kidney Stone
Effects of Abdominal Cushion on PCNL in Prone Position
Percutaneous nephrolithotomy (PCNL) is the first choice for the treatment of ≥ 2cm renal stones. The positions of PCNL includes supine, prone and lateral. PCNL has been performed in my center for nearly twenty years.
- Trial name
- NCT03797027
- Testing
- Percutaneous Nephrolithotomy without an abdominal cushion, Percutaneous Nephrolithotomy with an 5 cm abdominal cushion
- Where
- China
- Volunteers
- 180 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Secondary Hyperoxaluria, Nephrolithiasis
Lanthanum Carbonate (Fosrenol®) to Reduce Oxalate Excretion in Patients With Secondary Hyperoxaluria and Nephrolithiasis
This study investigates the efficacy and the safety of Lanthanum Carbonate for the reduction of urinary oxalate excretion in patients with secondary hyperoxaluria and nephrolithiasis.
- Trial name
- LaCa (NCT03346369)
- Testing
- Lanthanum Carbonate
- Where
- Belgium
- Volunteers
- 54 people
- Sponsor
- Universitair Ziekenhuis Brussel
Metabolic Acidosis, Nephrolithiasis
Alkalinization by Urologists & Nephrologists
Metabolic acidosis recovers a wide range of diseases in which an oral alkalinization could be useful. This therapeutic intervention has been said to increase extracellular volume leading to rising blood pressure.
- Conditions
- Metabolic Acidosis, Nephrolithiasis, Extracellular Alteration, Blood Pressure
- Trial name
- AlcalUN (NCT03035812)
- Testing
- Alkali
- Where
- 18 sites in France
- Volunteers
- 156 people
- Sponsor
- Jean-Philippe Bertocchio
Renal Stone
The Effect of Anesthesia Type on RIRS
Retrograde intrarenal surgery (RIRS) with flexible ureteroscopy is based on video monitoring of urinary tract during operation. Therefore, shaking vision on monitor can bother surgeons and make them tired.
- Trial name
- NCT03373617
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Seoul National University Hospital
Acute Renal Colic, Ureteric Stone
Parecoxib vs Paracetamol in the Treatment of Acute Renal Colic
This study will be conducted to compare the efficacy and safety of Parecoxib versus Paracetamol for treatment of acute renal colic due to ureteric stones.
- Trial name
- NCT03704623
- Testing
- Paracetamol, Parecoxib
- Where
- Kuwait
- Volunteers
- 200 people
- Sponsor
- Mansoura University
Kidney Stone, Nephrolithiasis
Evaluation of the LithoVue Elite Ureteroscope With Intra-Renal Pressure Monitoring Technology: Examination of Surgeon Behavior and Post-operative Outcomes
The goal of this study is to evaluate the influence of real-time intrarenal pressure measurement availability on surgeons' behavior during ureteroscopy while using the ureteroscope LithoVue Elite.
- Trial name
- ELITE (NCT06576661)
- Testing
- INTRARENAL PRESSURE MONITORING VISIBLE
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Renal Stones, Calculus
Comparison of ESWL and Mini-PCNL for High-Density Renal Stones in Children
Pediatric nephrolithiasis is an increasing health problem, with rising prevalence particularly in certain geographic regions. Management options for pediatric renal stones include extracorporeal shockwave lithotripsy (SWL)…
- Conditions
- Renal Stones, Calculus, Pediatric, Endoscopy
- Trial name
- NCT07360041
- Testing
- Miniaturized Percutaneous Nephrolithotomy (mini-PNL), Shock Wave Lithotripsy (SWL)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Kidney Stone
Predictors of Readmission in Patients Undergoing PNL
To identify predictors of patients postoperative readmission after PNL
- Trial name
- NCT05852483
- Where
- Egypt
- Volunteers
- 161 people
- Sponsor
- Assiut University
Kidney Stone, Urolithiasis
LithoVue Elite Registry
To obtain postmarket safety and efficacy data on Boston Scientific LithoVue™ Elite System.
- Trial name
- LVE (NCT05201456)
- Testing
- LithoVue Elite System
- Sponsor
- Boston Scientific Corporation
Renal Stones
Ultraslow SWL Versus Slow SWL for Renal Stones With High Attenuation Value
Ultraslow full-power SWL versus slow power-ramping SWL in Renal stones with high attenuation value
- Trial name
- ESWL (NCT03795532)
- Testing
- SWL
- Where
- Egypt
- Volunteers
- 124 people
- Sponsor
- Cairo University
Kidney Calculi
Ureteral Stent Placement After Ureteroscopy for Renal Stones: A Randomized Controlled Trial
The rationale for this study is to determine if there is a difference in complications among patients undergoing ureteroscopy for renal stones who receive a stent compared to not receiving a stent postoperatively.
- Trial name
- NCT03855787
- Testing
- Ureteroscopy
- Where
- 7 sites in United States, Canada
- Volunteers
- 103 people
- Sponsor
- Vanderbilt University Medical Center
Kidney Stone
Effectiveness of Urinary Alkalinizing Agents on Kidney Stone Risk
Randomized treatment trial of baking soda or LithoLyte to determine if baking soda and Litholyte are effective in raising 24 hour urine citrate and pH.
- Trial name
- NCT04095975
- Testing
- Baking Soda, LithoLyte
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Wisconsin, Madison
Nephrolithiasis, Urolithiasis
Perioperative Pregabalin in Ureteroscopy: a Pilot
The investigators propose a pilot clinical trial on the use of perioperative pregabalin in order to decrease ureteral stent related symptoms and decrease opioid usage after ureteroscopy with stent placement.
- Conditions
- Nephrolithiasis, Urolithiasis, Perioperative/Postoperative Complications, Pain, Postoperative
- Trial name
- NCT03927781
- Testing
- Pregabalin 300mg
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Missouri-Columbia
Acute Kidney Injury, Renal Calculi
Evaluation of Renal Damage After PCNL and ESWL Using Novel RNA Based Biomarkers
The study evaluate the damage effect of ESWL and PCNL on kidney tissue by measuring non-coding lnc-RNA profile in urine before and after ESWL and PCNL procedures
- Conditions
- Acute Kidney Injury, Renal Calculi, Percutaneous Nephrolithotomy, Extracorporeal Shockwave Lithotripsy
- Trial name
- NCT05077007
- Testing
- Percutaneous nephrolithotomy, Extracorporeal Shock Wave Lithotripsy
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Kidney Stone
Research Project: Pilot Study on Oral Urea Use in Patients at High Risk of Kidney Stone Recurrence
In clinical practice, many patients are not able to modify their habits to achieve a high level of diuresis and fluid intake and therefore are at an elevated risk for stone recurrence.
- Trial name
- Ure-Na (NCT04727606)
- Testing
- Ure-Na
- Where
- Canada
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Nephrolithiasis
Kidney Stone Structural Analysis By Helical Computed Tomography (CT)
Current practices of the diagnosis of urinary stones gives little information on the probable fragility of stones using shock wave lithotripsy (SWL), and many patients receive more SW's than is necessary to break up their stones.
- Trial name
- NCT00169780
- Testing
- High definition helical CT (64 head scanner)
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Indiana Kidney Stone Institute
Kidney Stone, Normal Controls
Oxalate and Citrate
This is a single-center study that aims to earn more about how two different compounds found in food, oxalate and citrate, may affect a person's chances of forming kidney stones.
- Trial name
- NCT05334979
- Testing
- Kidney stones Normal controls Consuming a special drink (sodium oxalate) during an all day visit to the University of Chicago research clinic
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Nephrolithiasis
Trial Assessing Renal Damage During Ureteroscopy
This is an ongoing randomized controlled trial of patients undergoing URSLL with unilateral non-obstructing renal stones. Patients are randomized to undergo URSLL with either the TFL or Ho:YAG laser.
- Trial name
- NCT05350423
- Testing
- Thulium Fibre Laser, Holmium:Yttrium-Aluminum-Garnet
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Urolithiasis
Litholytic Therapy for Coral Urate Nephrolithiasis
This is a prospective cohort study, patients with coralloid nephrolithiasis. Purpose of the study: to evaluate the efficacy and safety of litholytic therapy of coral-like urate nephrolithiasis with citrate mixtures.
- Trial name
- NCT07162974
- Testing
- anhydrous citric acid - 1197.0 mg, potassium bicarbonate - 967.5 mg, sodium citrate anhydrous - 835.5 mg
- Where
- Russia
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Moscow State University of Medicine and Dentistry