Clinical trials: Calculi
Dental Occlusion, Occlusal Wear of Teeth
Evaluation of Occlusal Adjustment Material Removal on Monolithic Zirconia Blocks: An In Vitro Study
This study aims to improve understanding of the amount of tooth-replacement material removed during a single grinding "stroke" performed in the adjustment of a zirconia crown.
- Conditions
- Dental Occlusion, Occlusal Wear of Teeth, Fixed Dental Prosthesis
- Trial name
- NCT07280130
- Testing
- perform material removal on monolithic zirconia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Nephrolithiasis
Evaluation of Genetic Abnormalities Amongst Calcium Phosphate Stone Formers
Kidney stones continue to affect more and more people in the United States with the most recent estimate being 1 in 9 people will develop a stone in their life.
- Trial name
- NCT06974357
- Testing
- Genetic testing
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Ryan L Steinberg
Cholelithiasis
Epidemiology of Gallbladder Sludge and Stones in Pregnancy
The specific objective of this project is to study the impact exercise has on gallstone formation during pregnancy when women are at increased risk due to biochemical and physiological alterations.
- Trial name
- NCT00131131
- Testing
- Exercise
- Where
- United States
- Volunteers
- 1,196 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Kidney Calculi
Quality of Life in Patients With Double Loop Ureteral Stent (JJ Silicone Hydrogel Study)
This study is a prospective, randomized multicenter study conducted in Europe. It is designed to compare two double loop ureteral stents in terms of the quality of life in patients operated on a kidney stone and requiring the…
- Trial name
- NCT02489656
- Testing
- Double Loop Ureteral stent endoscopic placement.
- Where
- France
- Volunteers
- 140 people
- Sponsor
- Coloplast A/S
Kidney Stone
Neutrophil Extracellular Traps (NET's) in Prevalent Kidney Stone
Neutrophils are first responders to any kind of threat the body faces: infection, severe trauma, cancer, surgery... They produce the cytokines, induct oxidative stress and de-granulate toxic proteins to kill pathogens.
- Trial name
- NCT06412822
- Testing
- Blood sampling, Urine sampling
- Where
- Belgium
- Volunteers
- 500 people
- Sponsor
- Brugmann University Hospital
Choledocholithiasis with Cholecystitis
For Patients with Stones in Gallbladder and Bile Duct Stones At the Same Time, Surgical Removal of the Gallbladder with the Laparoscope is Done in the Same Admission Compared to Its Removal After 6 Weeks Following Successful Removel of the Stones from the Bile Ducts by the Side View Endoscope
The goal of this clinical trial is to learn if early laparoscopic cholecystectomy is safe and feasible when performed during the same admission for patients with concomitant gallbladder and common bile duct stones after clearance…
- Trial name
- NCT06599437
- Testing
- laparoscopic cholecystectomy, Late laparoscopic cholecystectomy
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Damanhour Medical National Institute
Ureteral Calculi, Renal Calculi
Intraureteral Lidocaine for Post-Ureteroscopy Pain
Ureteroscopy (URS) is minimally invasive procedure for management of renal stones. URS is often involves concomitant of an indwelling ureteral stents.
- Trial name
- NCT01450566
- Testing
- Lidocaine, Saline
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Queen's University
Prostatic Hyperplasia
ALF-STONE: Alfuzosin in Uretheric Stones
The aim of the study is to assess the effect of Alfuzosin compared with placebo, for 7 days, on the outcome of patients with uretheric stones submitted to Extracorporeal Shock Wave Lithotripsy (ESWL), namely in the percentage of…
- Trial name
- NCT00454402
- Testing
- Alfuzosin
- Where
- Portugal
- Volunteers
- 220 people
- Sponsor
- Sanofi
Cystinuria
TCUPS- Tolvaptan Use in Cystinuria and Urolithiasis: A Pilot Study
The goal of this research project is to establish that in short-term use, tolvaptan is a safe and potentially effective new therapy for cystinuria, by conducting a short-term pilot study of the safety and tolerability of this…
- Trial name
- TCUPS (NCT02538016)
- Testing
- Tolvaptan
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Caleb Nelson
Endourology
Triangulation Bulls Eye and Stone Direct Targeting Pcnl
To assess the impact of percutaneous renal access technique on outcomes of percutaneous nephrolithotomy in management of renal stones by comparing the Triangulation and ''eye of the needle'' (or bull's eye) and the stone targeted…
- Trial name
- NCT04846699
- Testing
- per-cutaneous stone extraction
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Assiut University
Renal Calculi, Kidney Stones
Transient Apnea During Flexible Ureteroscopic Lithotripsy
Respiration-related renal motion may reduce targeting stability during flexible ureteroscopic laser lithotripsy and thereby decrease lithotripsy efficiency.
- Trial name
- TA-fURS (NCT01835600)
- Testing
- Regular mechanical ventilation during flexible ureteroscopic lithotripsy, Small tidal-volume ventilation during flexible ureteroscopic lithotripsy, Transient apnea during flexible ureteroscopic lithotripsy
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Chinese Medical Association
Renal Calculi
Comparison of Lithotomy Versus Lateral Position in Retrograde Intrarenal Surgery for Lower Calyceal Stones Less Than 2 cm
Retrograde intrarenal surgery (RIRS) is an established minimally invasive treatment for renal stones, particularly for lower calyceal stones less than 2 cm, offering acceptable stone-free rates with low morbidity.
- Trial name
- NCT07310966
- Testing
- Lithotomy Position, Lateral position
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Menoufia University
Gallbladder Malignant Neoplasm
A Case Series on Incidentally Detected Gallbladder Malignancy
A retrospective analysis of data, using the Hospital records of all the patients who underwent cholecystectomy for benign conditions at Osmania General Hospital in a year (2019).
- Trial name
- NCT05606029
- Testing
- Cholecystectomy, extended cholecystectomy
- Where
- India
- Volunteers
- 180 people
- Sponsor
- Osmania Medical College
Renal Stone Disease
Intrarenal Pressure Monitoring During Pediatric Percutaneous Nephrolithotomy, and Its Impact on Post Operative Infectious Complications.
Monitoring of intrarenal pressure during pediatric percutaneous nephrolithotomy and its impact on post operative infectious complications.
- Trial name
- NCT07800546
- Testing
- Intrarenal pressure
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Stone, Kidney
Mobile Health Platform for Surveillance of Kidney Stone
We plan to investigate whether usage of a mobile health platform for surveillance of stone formers by itself or as an adjunct to standard office-appointments will improve patient compliance and adherence to treatment guidelines…
- Trial name
- NCT05389982
- Testing
- mHealth (GetWell), Standard Care
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Northwestern University
Bladder Cancer, Urocystitis
A Multicenter Clinical Trial of Urine DNA Testing for Bladder Cancer in China
The primary objective of this study is to assess the safety and effectiveness of Human Multigene Methylation Detection Kit (Fluorescent PCR Method) for help diagnose bladder cancer by comparing with clinical standard method…
- Conditions
- Bladder Cancer, Urocystitis, Urinary Bladder Stone, Urothelial Carcinoma
- Trial name
- NCT05337189
- Testing
- Urine DNA methylation analysis, medical imaging and/or cystoscopy and/or pathological examination
- Where
- China
- Volunteers
- 482 people, healthy volunteers welcome
- Sponsor
- Creative Biosciences (Guangzhou) Co., Ltd.
Thulium Fiber Laser, Fans
Fragmentation Vs Dusting With FANS for Renal Stones Less Than 2cm: A Randomized Controlled Study
The use of FANS has changed the operative landscape of RIRS by allowing continuous active suction-assisted clearance of ablated stone material in real time.
- Conditions
- Thulium Fiber Laser, Fans, Lithotripsy, Laser, Renal Stone
- Trial name
- NCT07639385
- Testing
- Dusting, Fragmentation
- Volunteers
- 86 people
- Sponsor
- Bir Hospital
Cholelithiasis, Gall Stone
Bile Composition in Healthy and Gallstones Patients
Determine differences between lithogenic and non-lithogenic bile composition.
- Conditions
- Cholelithiasis, Gall Stone, Gall Bladder Disease
- Trial name
- NCT03981315
- Testing
- Bile test, Blood test, Gall stone study
- Where
- Spain
- Volunteers
- 62 people
- Sponsor
- Hospital Son Espases
Kidney Stone
Follow-Up of Ureteral Stones ≤4 mm
The goal of this clinical trial is to evaluate the proportion of ureteral stones ≤4 mm that pass spontaneously within 4 and 8 weeks and assess if pain, blood test (S-creatinine), stone size, stone location and hydronephrosis can…
- Trial name
- NCT07176026
- Where
- 2 sites in Sweden
- Volunteers
- 1,600 people
- Sponsor
- Region Skane
Kidney Stone, Healthy
Oxalate and Citrate in Humans - Response to Citrate
This is a single-center study that aims to learn more about how two compounds found in food, oxalate and citrate, interact in the body and may influence a person's chances of forming kidney stones.
- Trial name
- NCT06944223
- Testing
- Kidney stone formers, Control cohort
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Chicago