Clinical trials: Calculi
Tamsulosin, Silodosin
Comparison of Silodosin and Tamsulosin for Medical Expulsive Therapy in Patients With Ureteral Stones
This study compares the effectiveness and side effect profiles of Tamsulosin and Silodosin in medical expulsive therapy (MET) for ureteric stones.
- Conditions
- Tamsulosin, Silodosin, Medical Expulsive Therapy
- Trial name
- NCT06999135
- Testing
- Silodosin
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- Fatima Jinnah Medical University
Renal Stones
Prone Flexed Position in Percutanous Nephrolithotomy
prone flexed position in percutanous nephrolithotomy in comparsion with standard prone position. A randomized controlled trial.
- Trial name
- NCT04345835
- Testing
- Percutanous nephrolithotomy (PCNL)
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Kafrelsheikh University
Gingivitis, Plaque
Self-selection Study of the Toothwave Toothbrush
This study objective is to test the Silk'n Toothwave self-selection, by potential end users. Additionally, this study will evaluate if contraindicated subjects will self-exclude from use of the device and the ability to…
- Conditions
- Gingivitis, Plaque, Calculus, Tooth Discoloration
- Trial name
- NCT04023097
- Testing
- Toothwave toothbrush
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Home Skinovations Ltd.
Urothelial Carcinoma, Renal Cell Carcinoma
Prospective Trial for Examining Hematuria Using Computed Tomography
The primary objective is to evaluate whether one-phase nephrographic CT (experimental) is sufficient to detect urothelial cell carcinoma in patients with hematuria compared to the traditional four-phase CT (control).
- Conditions
- Urothelial Carcinoma, Renal Cell Carcinoma, Renal Cyst, Renal Stone
- Trial name
- PROTEHCT (NCT04077359)
- Testing
- CT
- Where
- Norway
- Volunteers
- 300 people
- Sponsor
- Oslo University Hospital
Kidney Stones
Ureteral Access Sheaths in Endoscopic Kidney Stone Surgery
This prospective, randomized, comparative study aims to evaluate the impact of aspirating and non-aspirating ureteral access sheaths on success rates and complications in patients undergoing retrograde intrarenal surgery (RIRS)…
- Trial name
- NCT07568990
- Testing
- Non-aspirating ureteral access sheath, Aspirating ureteral access sheath
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Hitit University
Kidney Stones
Donors With Nephrolithiasis at the Time of Transplant Evaluation (DONATE). Long Term Follow-up.
We believe that kidney donors with kidney stones accepted for a donation do not have an increased risk of loss of kidney function and will not be at increased risk of symptomatic kidney stone events compared to donors without a…
- Trial name
- DONATE (NCT05519150)
- Testing
- low dose radiation abdomen/pelvis CT scan (stone protocol), Blood draw, 24 hour urine collection
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Indiana University
Kidney Stone, Kidney Calculi
Outcomes of Using FANS With FURS in TTT of Lower Calyceal Stones.
The aim of this study is to evaluate and assess the outcomes of flexible ureteroscopy (FURS) with flexible and navigable suction UAS (FANS) in the treatment of lower calyceal stones.
- Trial name
- NCT07238803
- Testing
- flexible and navigable suction sheath with flexible ureteroscopy
- Where
- Egypt
- Volunteers
- 33 people
- Sponsor
- Zagazig University
Common Bile Duct Calculi, Acute; Cholecystitis, Choledocholithiasis
Modified Laparoscopic Transcystic Biliary Drainage in the Management of Cholecystocholedocholithiasis
The modified laparoscopic transcystic biliary drainage which we developed in the treatment of cholecystocholedocholithiasis has some advantages over conventional techniques.
- Conditions
- Common Bile Duct Calculi, Acute; Cholecystitis, Choledocholithiasis, Acute Cholecystitis With Obstruction, Acute Cholangitis
- Trial name
- NCT06011941
- Testing
- Modified laparoscopic transcystic biliary drainage
- Where
- China
- Volunteers
- 310 people
- Sponsor
- Peking University Third Hospital
Urinary Stone, Renal Injury
Urinary NGAL and KIM-1 After ESWL
The goal of this prospective observational study is to evaluate the effect of different time intervals between extracorporeal shock wave lithotripsy (ESWL) sessions on renal injury using urinary biomarkers in patients with…
- Trial name
- NCT07341269
- Testing
- No Interventions, No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Marmara University
Gallstone
The Discovery of the Double Sphincter in Gallbladder
We found a new Double sphincter which located in the neck of gallbladder，we supposed it may be related to control pressure of bile duct.Its formation is related to genetic factors.
- Trial name
- NCT01998451
- Testing
- Tauroursodeoxycholic acid
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Kidney Stone
Evaluation of the Efficacy and Safety of Unimodal Bilateral Flexible Ureteroscopy.
This is a prospective controlled study to compare the efficacy and safety of two methods of flexible urethroscopy in patients with urolithiasis, as well as the effect of surgery on quality of life.
- Trial name
- NCT05591716
- Testing
- Bilateral same-session flexible ureterorenoscopy, Unilateral same-session flexible ureterorenoscopy
- Where
- Russia
- Volunteers
- 86 people
- Sponsor
- St. Petersburg State Pavlov Medical University
Cholecystitis, Gall Stone Pancreatitis
Randomized Control Trial of Intraperitoneal Bupivacaine During Cholecystectomy
Laparoscopic cholecystectomy (removal of the gall bladder via 'keyhole surgery') is a common procedure. This can be performed as an emergency operation when a patient has a complication of gall stones such as acute inflammation…
- Trial name
- NCT01528722
- Testing
- Bupivacaine, Normal saline
- Where
- United Kingdom
- Volunteers
- 42 people
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Urinary Stone, Urinary Calculi
Ultrasound to Facilitate Stone Passage
This is a prospective, open-label, multi-center study to test the clinical feasibility of facilitating stone passage by the combination of breaking and repositioning stones with ultrasound, without the need for anesthesia.
- Trial name
- NCT04796792
- Testing
- Burst Wave Lithotripsy (BWL) and Ultrasonic Propulsion (UP)
- Where
- 3 sites in United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Washington
Urinary Tract Stones, Pain
Pain and Anxiety During Extracorporeal Shock Wave Lithotripsy
Investigators observed that during the Extracorporeal Shock Wave Lithotripsy (ESWL) non-pharmacological methods used for reducing the level of the pain and anxiety among the patients with the urinary stones are not sufficient and…
- Conditions
- Urinary Tract Stones, Pain, Anxiety
- Trial name
- NCT02725281
- Testing
- Stress ball, Music
- Volunteers
- 120 people
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Physical Activity, Breast Neoplasm
The Impact of Physical Activity on the Outcome of Surgery
Over the last decades different life style factors have been established as risk factors for various diseases. The obesity pandemic displays a good example of a disease where great effort is undertaken to characterize risk…
- Conditions
- Physical Activity, Breast Neoplasm, Colorectal Neoplasm, Gall Stones
- Trial name
- NCT01707121
- Where
- 2 sites in Sweden
- Volunteers
- 450 people
- Sponsor
- Sahlgrenska University Hospital
Urolithiasis
Urine and Stool Analysis in Kidney Stone Disease
The purpose of this study is to add to the investigators' quest to understanding stone disease, by evaluating the metabolites excretion in urine and its relation to microflora present in the stool.
- Trial name
- NCT01637506
- Where
- 2 sites in Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Urinary Calculi, Benign Prostatic Hyperplasia
Flexiva Pulse Registry
To obtain post-market safety and efficacy data for FlexivaTM Pulse High Power Single-Use Laser Fibers during lithotripsy and soft tissue procedure of holmium laser enucleation of the prostate (HoLEP).
- Trial name
- NCT05027971
- Testing
- Flexiva Pulse High Power Single-Use Laser Fibers
- Where
- 4 sites in United States
- Volunteers
- 201 people
- Sponsor
- Boston Scientific Corporation
Kidney Stones
Feasibility of Radiation-Free Percutaneus Nephrolithotomy for Kidney Stones
The goal of this observational study is to investigate the feasibility of ultrasound-guided percutaneus nephrolithotomy in patients with kidney stones.
- Trial name
- PCNL (NCT06922006)
- Testing
- Percutaneus nephrolithotomy (PCNL)
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- University of California, San Diego
Nephrolithiasis
Comparison of DASH With Oxalate Restricted Diet on Urine in Recurrent Stone Formers With Hyperoxaluria
Oxalate restricted diet is routinely prescribed in clinical practice of nephrolithiasis patients with hyperoxaluria. The effect of dietary oxalate on urinary oxalate is however controversial.
- Trial name
- NCT01650935
- Testing
- diet
- Where
- 2 sites in Iran
- Volunteers
- 48 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Kidney Stone, Renal Stone
Antibiotic Selection Using Next Generation Sequencing vs Urine Culture
This is a randomized controlled clinical study evaluating the use of next-generation sequencing (NGS) to improve antibiotic prescribing before ureteroscopy or percutaneous nephrolithotomy.
- Conditions
- Kidney Stone, Renal Stone, Infection, Bacterial
- Trial name
- ACCESS (NCT04404855)
- Testing
- NGS + Antibiotic Recommendation, Standard of Care treatment
- Where
- 3 sites in United States
- Volunteers
- 240 people
- Sponsor
- The University of Texas Health Science Center at San Antonio