Clinical trials: Calprotectin
Malnourished Children
Effects of Channa Striata Extract on Intestinal Inflammation and Nutritional Status in Malnutritional Toddlers After Albendazole Therapy in South Bangka District
The goal of this clinical trial is to learn if intervention with channa striata extract or inbumin forte sachet as a food supplement can improve intestinal damage and nutritional status in malnourished children aged 1.5-5 years.
- Trial name
- Striatin1 (NCT06933862)
- Testing
- Striatin
- Where
- 2 sites in Indonesia
- Volunteers
- 122 people
- Sponsor
- Universitas Indonesia
Ulcerative Colitis (UC)
The Effects of a Modified Mediterranean Diet on Ulcerative Colitis Patients
Ulcerative colitis is a chronic disease with a significant impact on quality of life where a substantial proportion of patients fails to achieve disease remission.
- Trial name
- OLIVE-UC-1 (NCT07857447)
- Testing
- Modified Mediterranean Diet, Standard Nutritional Guidance
- Where
- Croatia
- Volunteers
- 62 people
- Sponsor
- University Hospital Sestre Milosrdnice
Necrotizing Enterocolitis
Ultrasound, Doppler ,and Calprotectin in Necrotizing Enterocolitis Diagnosis
Necrotizing enterocolitis continues to be a disease that is associated with significant morbidity and mortality in premature infants due to advances in neonatal intensive care that increase the survival rate of extremely low…
- Trial name
- NCT03257553
- Testing
- fecal calprotectin , doppler and ultrasound
- Volunteers
- 50 people
- Sponsor
- Assiut University
Gastrointestinal, Colic
Safety and Effect of L. Reuteri on Biomarkers of Inflammation in Healthy Infants With Colic
This protocol is a study of the effects of Lactobacillus reuteri in 45 healthy infants with colic. The study is being conducted in order to prove treatment dose with probiotic (Lactobacillus reuteri) in a clinical setting is safe…
- Trial name
- NCT01849991
- Testing
- Lactobacillus reuteri
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Diarrhea, Immunosuppression
Fecal Calprotectin Levels in Mycophenolate Mofetil Induced Diarrhea and Treatment With Octreotide
Prospective, observational pilot study of ten post-transplant patients presenting with diarrhea while taking Mycophenolate Mofetil (MMF). These patients will undergo a standard workup to confirm MMF induced diarrhea.
- Trial name
- NCT02977897
- Testing
- Octreotide Acetate
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University Health Network, Toronto
Acute Diarrhea
Fecal Calprotectin: Cheap Marker for Diagnosing Acute Infectious Diarrhea
Every year more than 4 billion cases of diarrhea occur worldwide culminating in about 2.5 million deaths, almost all in the developing nations.
- Trial name
- NCT00429325
- Where
- 2 sites in Germany
- Volunteers
- 400 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Inflamatory Bowel Disease (Crohn's and Ulcerative Colitis), Inflamatory Bowel Disease
Physical Activity and Fitness in Pediatric Inflammatory Bowel Disease
Pediatric inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, is a chronic condition associated not only with intestinal inflammation but also with reduced physical fitness, fatigue, impaired…
- Trial name
- PAFIT-IBD (NCT07484620)
- Testing
- Physical Activity Intervention
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Universidad Complutense de Madrid
Inflammatory Bowel Diseases, Irritable Bowel Syndrome
The Comparison Between the Biomarkers in Inflammatory Bowel Disease Patients and General Control Group
The aims of this study is to investigate a blood-based biomarker that can replace endoscopy in patients with inflammatory bowel disease.
- Trial name
- NCT03778918
- Testing
- inflammatory bowel disease, IBS or Normal Control
- Where
- South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bo-In Lee
Spondylarthritis
Seric Calprotectine in Spondyloarthritis
To date, there are no biomarkers in spondyloarthritis that can differentiate between spondyloarthritis and fibromyalgia or other pathologies.
- Trial name
- Calprotect (NCT03818958)
- Testing
- blood sampling
- Where
- France
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Inflammatory Bowel Diseases, Morbus Crohn
Diagnosis of Inflammatory Bowel Disease by Examining the Entire Bowel by Pan-intestinal Capsule Endoscopy
The aim of this study is to discover inflammatory changes in the gastrointestinal tract in adult patients with suspicion of a chronic inflammatory bowel disease (IBD) by examining the entire bowel, including the small intestine…
- Trial name
- PEC (NCT04904224)
- Testing
- Panintestinal video capsule endoscopy, Colonoscopy
- Where
- 6 sites in Germany
- Volunteers
- 150 people
- Sponsor
- Robert Bosch Medical Center
Severe/Moderate Coronavirus, Chronic Myelomonocytic Leukemia
Calprotectin, a Biomarker of COVID-19 Severity (CALPRO)
The purpose of this study is to provide new insights into the pathophysiology of emergency hematopoiesis detected in severe COVID-19 patients.
- Conditions
- Severe/Moderate Coronavirus, Chronic Myelomonocytic Leukemia, Myelodysplastic Syndromes, Old Age
- Trial name
- CALPRO (NCT04953312)
- Testing
- Blood samples
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chronic Granulomatous Disease-associated Colitis
Fecal Microbiota Transplantation for Chronic Granulomatous Disease-Associated Colitis
Background: Chronic granulomatous disease (CGD) weakens the body's defense against germs. CGD can also damage the colon. It can cause inflammation (colitis) that disrupts the good bacteria.
- Trial name
- NCT05333471
- Testing
- MTP 101-LF
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Ulcerative Colitis
A Prospective Non-interventional Multicenter Study to Evaluate the Effectiveness of Adalimumab in Korean Patients With Ulcerative Colitis (UC) and Identify Potential Predictors of Clinical Response in Routine Clinical Practice
This is a prospective, single country, multi-center study in participants with ulcerative colitis (UC) treated with adalimumab. Up to 147 participants are enrolled at approximately 20 sites.
- Trial name
- EUREKA (NCT02499263)
- Where
- 19 sites in South Korea
- Volunteers
- 150 people
- Sponsor
- AbbVie
Inflammatory Bowel Diseases
Urinary PGE-MUM (PROSTAGLANDIN E-MAJOR URINARY METABOLITE) as Inflammatory Marker in Chronic Inflammatory Bowel Disease
The inflammatory bowel diseases (IBD) are lifelong, relapsing-remitting diseases. As the timing of relapse is unpredictable, and current monitoring is symptoms-based, there remains a window between the initial upregulation of the…
- Trial name
- MICIMUM (NCT05171452)
- Testing
- Urine and stoll samples
- Where
- France
- Volunteers
- 101 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Crohn Disease
Predictive Factors of Clinical Response to Ustekinumab in Active Crohn's Disease
Ustekinumab is a fully human Immune Globulin Gk (IgGk) monoclonal antibody against the common p40 subunit of interleukin-12 and interleukin-23, which are implicated in the pathogenesis of inflammatory bowel disease.
- Trial name
- SAFARI (NCT03351647)
- Testing
- Evaluation of biological predictive factors of clinical response to ustekinumab
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Hospices Civils de Lyon
Crohn's Disease
Calprotectin-Directed Humira® Maintenance Therapy (CADHUM)
This is a study that invites adults with Crohn's disease and have been responding well to Adalimumab (Humira ®) for at least 6 months.
- Trial name
- CADHUM (NCT01674413)
- Testing
- Adalimumab, Adalimumab PRN
- Where
- United States
- Sponsor
- Peter Higgins
Diabete Type 1
Effect of a Probiotic Supplement on Gut Microbiota and Glycemic Control in Patients With Type 1 Diabetes (PRODIAB)
This randomized, double-blind clinical trial aims to evaluate the effect of a probiotic supplement on gut microbiota composition and glycemic control in adults with type 1 diabetes mellitus.
- Trial name
- PRODIAB (NCT07062224)
- Testing
- Probiotic/Prebiotic Supplement
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Inflammatory Bowel Diseases
A Diagnostic Accuracy Study Testing Fecal Biomarkers In Comparison To Endoscopic Examination
In this study it will be explored whether the levels of fecal biomarkers are associated with histologic inflammation of the intestinal mucosa and concomitant alteration of the mucosal permeability.
- Trial name
- NCT04849936
- Testing
- Testing Fecal Biomarkers In Comparison To Endoscopic Examination With Confocal Laser Endomicroscopy
- Where
- Germany
- Volunteers
- 300 people
- Sponsor
- Universität Duisburg-Essen
Blastocystis Infections
Efficacy of Calprotectin as A Marker For the Pathogenicity of Blastocystis Infection
Blastocystis which is commonly found in the gastro-intestinal tract, has been recognized as a non-pathogenic organism for a few decades. It has a variable distribution.
- Trial name
- NCT05724368
- Testing
- Fecal Calprotectin ELISA kit
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Sohag University
Infection, Intraabdominal, Sepsis Abdominal
Serum Calprotectin in Surgical Septic Patients
To early evaluate the serum levels of calprotectin in patients suffering from intra-abdominal sepsis requiring a surgical treatment.
- Conditions
- Infection, Intraabdominal, Sepsis Abdominal, Biomarker
- Trial name
- NCT06614088
- Testing
- serum calprotectin
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Azienda Ospedaliero, Universitaria Pisana