Clinical trials: Cancer, Bladder
Superficial Bladder Cancer
Sequential Whole Bladder Photodynamic Therapy (WBPDT) in the Management of Superficial Bladder Cancer
This protocol is evaluating efficacy and toxicity of three sequential whole bladder photodynamic treatment with Photofrin and red laser light (630 nm) in the management of superficial bladder cancer (non-muscle invasive) in those…
- Trial name
- NCT00322699
- Testing
- Whole bladder laser light treatment as an alternative to radical cystectomy, Photofrin
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- North Florida/South Georgia Veterans Health System
Lymphoma, Digestive System Diseases
Development of an Evaluation Method of Elderly Condition in Patient Receiving Chemotherapy Treatment
Incidence of cancer in 75+ years old is 16,500 new cases per year, more than fifty percent of people with cancerThey are very few therapeutic trials dedicated.
- Conditions
- Lymphoma, Digestive System Diseases, Ovarian Diseases, Pulmonary Disease
- Trial name
- PHRC2003 (NCT00210249)
- Where
- 18 sites in France
- Volunteers
- 364 people
- Sponsor
- Institut Bergonié
Bladder Neoplasms
Safety and Proof of Concept Study of Intravesical DTA-H19 in Patients With Superficial Bladder Cancer
This study is designed to assess the safety and preliminary efficacy of five different doses of DTA-H19 given as six intravesical infusions into the bladder of patients with superficial bladder cancer who have failed intravesical…
- Trial name
- NCT00393809
- Testing
- DTA-H19
- Where
- 2 sites in Israel
- Volunteers
- 18 people
- Sponsor
- Hebrew University of Jerusalem
Prostate Cancer (Post Prostatectomy), Bladder Cancer
Adaptive Radiotherapy for Genitourinary Cancers
The goal of this clinical trial is to learn if adaptive radiation boost works to treat genitourinary cancers, esp. in the context of prostate cancer patients with post-prostatectomy local relapse and bladder cancer patients with…
- Trial name
- SMART-B01 (NCT07324798)
- Testing
- adaptive RT
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Bladder Cancer, BCG
Sequential Intravesical Gemcitabine and Docetaxel for Rescue Therapy in BCG Unresponsive Non-muscle Invasive Bladder Cancer Patients
Studies in the literature are limited both throughout Turkey and in general. For this reason, as a result of the study that we will create, it will provide us with information for bladder protective treatments in patients who do…
- Conditions
- Bladder Cancer, BCG, Gemcitabine, Docetaxel
- Trial name
- NCT06374914
- Testing
- Intravesical Solution
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Dokuz Eylul University
Prostate Cancer, Bladder Cancer
Use of PET/MRI Tracer to Further Understanding of Prostate Cancer Development
The purpose of this study is to develop a novel technique for integrated PET/MRI tracer kinetic analysis for urologic malignancy.
- Trial name
- NCT02106416
- Testing
- PET/MRI
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Bladder Cancer
Markers of Response to Intravesical Bladder Cancer Therapy
The goal of this laboratory research study is to see if researchers can predict whose cancer will stay in remission and whose will return in patients receiving treatment for bladder cancer.
- Trial name
- NCT01007058
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- M.D. Anderson Cancer Center
Non-Muscle Invasive Bladder Neoplasms, Urinary Bladder Neoplasms
BladMetrix Urine Test for Monitoring Recurrence in Non-Muscle Invasive Bladder Cancer
This observational study evaluates the urine test BladMetrix for monitoring bladder cancer recurrences in people with non muscle invasive bladder cancer (NMIBC) who are in follow-up after surgery.
- Conditions
- Non-Muscle Invasive Bladder Neoplasms, Urinary Bladder Neoplasms, Carcinoma, Transitional Cell, Bladder
- Trial name
- BladMetrix (NCT07511517)
- Testing
- BladMetrix urine test
- Where
- 6 sites in Norway
- Volunteers
- 500 people
- Sponsor
- Oslo University Hospital
Liver Cirrhosis, Refractory Ascites
ALFApump System Post Marketing Surveillance Registry
This is a post market surveillance registry to monitor the safety and performance of the ALFApump system.
- Conditions
- Liver Cirrhosis, Refractory Ascites, Malignant Ascites
- Trial name
- 2011-AAR-004 (NCT01532427)
- Where
- 13 sites in Germany, Spain and 2 more
- Volunteers
- 100 people
- Sponsor
- Sequana Medical N.V.
Bladder Cancer
Clinical Evaluation of BCDx for Monitoring of Recurrence in Non-Muscle Invasive Bladder Cancer
BCDx is a urine-based multi-omic assay for early cancer recurrence detection in patients with a history of bladder cancer. This prospective, blinded study evaluates its efficacy in detecting recurrent NMIBC, offering a…
- Trial name
- NCT05982561
- Where
- 3 sites in United States
- Volunteers
- 500 people
- Sponsor
- Early is Good Inc.
Locally Advanced Urothelial Carcinoma, Metastatic Urothelial Carcinoma
Testing the Addition of Tazemetostat to the Immunotherapy Drug, Pembrolizumab (MK-3475), in Advanced Urothelial Carcinoma
This phase I/II trial studies the side effects and best dose of tazemetostat and how well it works when given together with pembrolizumab in treating patients with urothelial carcinoma that has spread to nearby tissue or lymph…
- Conditions
- Locally Advanced Urothelial Carcinoma, Metastatic Urothelial Carcinoma, Stage III Bladder Cancer AJCC v8, Stage IV Bladder Cancer AJCC v8
- Trial name
- NCT03854474
- Testing
- Biospecimen Collection, Computed Tomography, Magnetic Resonance Imaging
- Where
- 34 sites in United States, Canada
- Volunteers
- 30 people
- Sponsor
- National Cancer Institute (NCI)
Bladder Cancer, Metastatic Bladder Cancer
A Window of Opportunity Trial: Avelumab in Non-metastatic Muscle Invasive Bladder Cancer
This is a pilot study of avelumab in patients with non-metastatic, muscle invasive bladder cancer who are eligible for radical cystectomy (RC), but are ineligible for cisplatin based neoadjuvant therapy.
- Conditions
- Bladder Cancer, Metastatic Bladder Cancer, Invasive Bladder Cancer
- Trial name
- NCT03498196
- Testing
- Avelumab
- Where
- 3 sites in United States
- Volunteers
- 1 people
- Sponsor
- Baylor College of Medicine
Muscle-Invasive Bladder Carcinoma
AURORAX-0093A: Glycosaminoglycan Profiling for Prognostication of Muscle-invasive Bladder Cancer - a Pilot Study
AURORAX-0093A (AUR93A) is a pilot cohort observational study that will explore the use of urine and plasma glycosaminoglycans (GAGs) to prognosticate muscle-invasive bladder cancer (MIBC) patients elected for neo-adjuvant…
- Trial name
- AUR93A (NCT05028660)
- Testing
- GAG score
- Where
- 5 sites in Denmark, Italy and 1 more
- Volunteers
- 43 people
- Sponsor
- Elypta
Transition Cell Cancer
Is the Normal Looking Bladder Mucosa on WL Cystoscopy During TURBT Really Normal and Can NBI Detect Hidden Tumor
As every urologist does transurethral resection of bladder tumor. So there are instances in which the operating surgeon is not sure whether the normal-looking mucosa or the inflammatory changes are really benign or if we are…
- Trial name
- NCT06729346
- Where
- 2 sites in Pakistan
- Volunteers
- 100 people
- Sponsor
- Armed Forces Institute of Urology, Rawalpindi
Bladder Cancer
The Global En Bloc Resection of Bladder Tumour Registry
The study aims to collect data on ERBT globally in order to clarify its role in the management of bladder cancer over a 5-year observation period.
- Trial name
- NCT04934540
- Testing
- En bloc resection of bladder tumour
- Where
- 2 sites in Hong Kong
- Volunteers
- 5,000 people
- Sponsor
- Chinese University of Hong Kong
Muscle Invasive Bladder Cancer, Surgery
To Better Understand the Most Important Factors for Patients When They Decide on the Type of Treatment They Receive for Muscle Invasive Bladder Cancer (MIBC).
Through our study, we aim to understand the most important factors for patients when they decide on the type of treatment they receive for MIBC.
- Conditions
- Muscle Invasive Bladder Cancer, Surgery, Sexual Wellbeing, Patient Satisfaction
- Trial name
- NCT05236218
- Testing
- Discrete Choice Experiment (DCE) Patients DCE Questionnaire, Semi-Structured Interview Patients Interview
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- King's College London
Transitional Cell Bladder Cancer, Cystectomy
Radical Cystectomy Versus Tri-Modal Therapy for Treatment of cT2N0M0 Urinary Bladder Transitional Cell Carcinoma
the aim of this study is to compare the oncological outcome of trimodal therapy with bladder preservation using maximal resection with chemoradiation versus the standard radical cystectomy for muscle invasive transitional cell…
- Conditions
- Transitional Cell Bladder Cancer, Cystectomy, Radiation
- Trial name
- NCT07043790
- Testing
- Radical cystectomy with pelvic lymphadenectomy, Trimodal therapy
- Where
- Egypt
- Volunteers
- 73 people
- Sponsor
- Ain Shams University
Cancer
Laboratory Assay in Determining Cancer Resistance in Patients With Metastatic Cancer and in Healthy Participants
RATIONALE: Studying samples of blood and tissue in the laboratory from patients with cancer and from healthy participants may help doctors learn more about cancer.
- Trial name
- NCT00899496
- Testing
- immunological diagnostic method, physiologic testing
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Bladder Cancer, Non-Muscle-Invasive Bladder Cancer (NMIBC)
Supporting Sexual Health in Bladder Cancer Patients: A Sequential Mixed-Methods Intervention Study
Despite increasing recognition of sexual dysfunction and sexual distress as important survivorship issues in oncology, research and clinical attention remain uneven across cancer types.
- Conditions
- Bladder Cancer, Non-Muscle-Invasive Bladder Cancer (NMIBC), Muscle-Invasive Bladder Carcinoma
- Trial name
- SPICE (NCT07339761)
- Testing
- Sexological Support
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- University of Aarhus
Bladder Cancer
Prediction of Impaired Survival in Elderly Bladder Cancer Patients Opting for Radical Cystectomy
The investigators proposes a prospective cohort study in patients with high risk bladder cancer who have opted for radical cystectomy.
- Trial name
- NCT02039310
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- University of Michigan
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.