Clinical trials: Cancer Abdomen
Acute Postoperative Pain
Combined Epidural Morphine and Midazolam on Postoperative Pain
this study aim to Compare the effect of preoperative Epidural Midazolam, Morphine and their combination in postoperative pain relief and total morphine consumption.
- Trial name
- NCT04033471
- Testing
- midazolam
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Assiut University
Pain
Comparison of Patient Controlled & Continuous Epidural Analgesia in Thoraco-abdominal Surgeries in Cancer Patients
This study aims to compare the efficacy of pain control, the consumption of local anesthetic and opioids, side effects, and patient satisfaction between continuous epidural infusion and patient controlled epidural analgesia after…
- Trial name
- NCT02803385
- Testing
- Continous Epidural Analgesia, Patient Controlled Epidural Analgesia
- Where
- India
- Volunteers
- 70 people
- Sponsor
- Tata Memorial Centre
Carcinomatosis, Peritoneal, Pancreas Cancer
Characterization of Biophysical Stromal Properties in Human Cancer: Towards Personalized Computational Oncology
Drug delivery in solid tumors, whether administered systemically or locoregionally, is hindered by an elevated interstitial fluid pressure (IFP).
- Conditions
- Carcinomatosis, Peritoneal, Pancreas Cancer, Ovarian Cancer, Colon Cancer
- Trial name
- DCE-MRI (NCT04512209)
- Testing
- MRI
- Where
- Belgium
- Volunteers
- 22 people
- Sponsor
- University Hospital, Ghent
Abdominal Cancer, Pelvic Cancer
A Study to Determine Whether Perioperative Energy Dynamics Correlates With Postoperative Outcomes
To validate a new method for assessing perioperative risk in the cancer patient undergoing major cancer surgery. In this proposed study researchers will: 1. Measure preoperative energy reserve capacity (fitness) 2.
- Trial name
- NCT00493688
- Testing
- Cardiopulmonary Exercise Testing (CPET)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- M.D. Anderson Cancer Center
Liver Cirrhosis, Hepatocellular Carcinoma
Combining Biomarkers (AFP, AFP-L3, and PIVKA-II) and Image Tools for Early Detection of Hepatocellular Carcinoma
In this study, three biomarkers tests (AFP, AFP-L3 and PIVKA-II) and abdominal sonography or CT scans are performed every 6 months to detect hepatocellular carcinoma (HCC) early in patients with cirrhosis, a high-risk group of…
- Conditions
- Liver Cirrhosis, Hepatocellular Carcinoma, Surveillance
- Trial name
- NCT04414956
- Testing
- AFP-L3, AFP, PIVKA-II
- Where
- 15 sites in South Korea
- Volunteers
- 1,418 people
- Sponsor
- Korea University
Gastric Adenocarcinoma With Peritoneal Carcinomatosis, Siewert Type II Adenocarcinoma of Esophagogastric Junction With Peritoneal Carcinomatosis
Catumaxomab for Treatment of Peritoneal Carcinomatosis in Patients With Gastric Adenocarcinomas
The purpose of this study is to determine the efficacy of catumaxomab by determination of the rate of macroscopic complete remissions of peritoneal carcinomatosis after treatment with one cycle (four doses) of catumaxomab…
- Conditions
- Gastric Adenocarcinoma With Peritoneal Carcinomatosis, Siewert Type II Adenocarcinoma of Esophagogastric Junction With Peritoneal Carcinomatosis, Siewert Type III Adenocarcinoma of Esophagogastric Junction With Peritoneal Carcinomatosis
- Trial name
- CatuNeo (NCT01504256)
- Testing
- catumaxomab, Fluorouracil, leucovorin, oxaliplatin, docetaxel, Fluorouracil, leucovorin, oxaliplatin, docetaxel
- Where
- Germany
- Volunteers
- 42 people
- Sponsor
- AIO-Studien-gGmbH
Renal Cell Carcinoma
Yorkshire Kidney Screening Trial
Kidney cancer is the 8th most common cancer in Yorkshire. It has a poor survival rate, with only 6 out of 10 patients diagnosed with kidney cancer still alive after 5 years.
- Trial name
- YKST (NCT05005195)
- Testing
- Low dose abdominal computed tomography scan
- Where
- United Kingdom
- Volunteers
- 5,850 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Abdominal Wound Dehiscence, Necrotizing Soft Tissue Infection
Myriad™ Augmented Soft Tissue Reconstruction Registry
This is an observational study designed to evaluate the safety and clinical outcomes of Myriad™ in soft tissue reconstruction procedures.
- Conditions
- Abdominal Wound Dehiscence, Necrotizing Soft Tissue Infection, Lower Extremity Wound, Pilonidal Sinus
- Trial name
- MASTRR (NCT05243966)
- Testing
- Myriad Matrix™ and Myriad Morcells™
- Where
- 15 sites in United States
- Volunteers
- 800 people
- Sponsor
- Aroa Biosurgery Limited
Thoracic Neoplasm, Liver Cancer
Mechanically-assisted Ventilation in the Treatment of Moving Tumours With Photon and Proton Therapies
Mechanical ventilation can be used to impose a completely regular pattern of breathing frequency and inflation volume on the patient for as long as required.
- Conditions
- Thoracic Neoplasm, Liver Cancer, Ventilator Lung, Radiotherapy; Complications
- Trial name
- NCT03226925
- Testing
- Non-invasive mechanically-assisted ventilation, Dynamic MRI acquisition, Planning 4D-CT
- Where
- Belgium
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Colorectal Neoplasms, Colitis, Ulcerative
Post-Op Quality of Life After Colorectal Surgery
The purpose of this study is to produce a user-friendly tool- in the form of a questionnaire - to accurately assess early quality of life in patients after abdominal colorectal surgery from the first day after surgery to 6 months…
- Conditions
- Colorectal Neoplasms, Colitis, Ulcerative, Diverticulitis, Colonic Polyps
- Trial name
- NCT00468455
- Testing
- Laparoscopic or open colorectal surgery
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University Hospitals Cleveland Medical Center
Endometrial Cancer
Whole-Abdominal Radiation Therapy and Cisplatin in Treating Patients With Stage III or Stage IV Endometrial Cancer That Has Been Removed by Surgery
RATIONALE: Drugs used in chemotherapy, such as cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00448643
- Testing
- Vaginal Brachytherapy, Cisplatin, Whole Abdominal Radiation [WAR] Therapy
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Miami
Peritoneal Carcinosis (PC)
Treatment of Primary Peritoneal Carcinosis of Digestive Origin Using Cytoreductive Surgery and Hyperthermic Intraoperative Peritoneal Chemotherapy With Mitomycin C and Irinotecan
This is an open, non-randomized, phase I-II, pilot study, which evaluates the combination of optimum cytoreductive surgery and hyperthermic intraoperative peritoneal chemotherapy (HIPEC) with mitomycin C (MMC) and irinotecan.
- Trial name
- NCT01226550
- Testing
- cytoreductive surgery and HIPEC
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Hospices Civils de Lyon
Upper Abdominal Malignancies
Liver Volume Variation Effect on SBRT Planning and Delivery for Upper Abdominal Malignancies
Standard planning constraints for liver SBRT incorporate strict dose-volume limits for normal liver parenchyma to minimize the risk of radiation-induced liver disease.
- Trial name
- NCT06355895
- Testing
- Standardized high-carbohydrate meal
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Pittsburgh
Gynecologic Malignancy, Abdominal Surgery by Laparotomy
Mindful Movement and Breathing to Improve Outcomes of Gynecologic Surgery
The purpose of this clinical trial is to understand if women undergoing surgery for a suspected gynecologic malignancy are interested in participating in a Mindful Movement and Breathing program and what the effects of this…
- Conditions
- Gynecologic Malignancy, Abdominal Surgery by Laparotomy, Pain, Psychological Distress
- Trial name
- NCT01593657
- Testing
- Mindful Movement and Breathing program, Questionnaire administration, The Observer Mobility Scale
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Wake Forest University Health Sciences
Postoperative Complications, Cancer
Predictive Value of Ariscat Index In The Development of Pulmonary Complication After Major Abdominal Cancer Surgery
The term postoperative pulmonary complication is the development of any complications affecting the respiratory system after anesthetic and surgery procedures.
- Conditions
- Postoperative Complications, Cancer, Pulmonary Complication, Atelectasis
- Trial name
- NCT04663958
- Testing
- Detection / Screening
- Where
- Turkey (Türkiye)
- Volunteers
- 410 people, healthy volunteers welcome
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Sarcoma, Soft Tissue, Retroperitoneal Neoplasms
Long Term Morbidity and Quality of Life in Retroperitoneal Sarcomas
No prospective data exist about long term morbidity and quality of life after multivisceral surgical resection for retroperitoneal soft tissue sarcoma (RSTS).
- Conditions
- Sarcoma, Soft Tissue, Retroperitoneal Neoplasms, Surgery, Quality of Life
- Trial name
- LTM (NCT03480399)
- Volunteers
- 60 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Cancer, Hepatic, Cancer, Esophagus
Expectation, Pain Outcomes, and Pain Medication Following Oncology Abdominal Surgery: A Cohort Study
This study includes participants undergoing major hepatic surgery, surgery in the esophagus or stomach, or major surgery on the pancreas performed at Copenhagen University Hospital, Rigshospitalet.
- Conditions
- Cancer, Hepatic, Cancer, Esophagus, Cancer, Pancreas
- Trial name
- NCT07176052
- Testing
- cancer surgery
- Volunteers
- 200 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Any Solid Malignancies of Any Tissue Origin (Except for Small Cell Lung Cancer) Involving the Upper Abdomen and Thorax
Novel Optical Surface Image Guidance System for Beam-Gated Online Adaptive SBRT Delivery in Mobile Lower Lung and Upper Abdominal Malignancies
Motion during radiation therapy can be categorized as inter-fraction (changes in anatomy that occur between treatment days) and intra-fraction (changes that occur during the "beam on" window of treatment delivery).
- Trial name
- NCT05030454
- Testing
- ETHOS, CT-guided stereotactic adaptive radiotherapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Washington University School of Medicine
Gastrointestinal Malignancy, Pain Control
The Erector Spinae Plane Block For Gastrointestinal Malignancy Pain Treatment (EGIPT)
This study will target patients with gastrointestinal (GI) malignancy who present to any of 4 Penn Medicine emergency departments (EDs) with intractable abdominal pain.
- Trial name
- EGIPT (NCT07211386)
- Testing
- Erector Spinae Plane Block
- Where
- 4 sites in United States
- Volunteers
- 25 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Pancreatic Cancer
EUS-guided Celiac Plexus Neurolysis for the Treatment of Abdominal Pain in Pancreatic Cancer
Studies have shown that injecting local anesthetics in areas rich in blood vessels increases the risk of drug injection into blood vessels by mistake and increases the systemic absorption of drugs, which may increase the…
- Trial name
- NCT03940027
- Testing
- EUS-guided celiac plexus neurolysis
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Changhai Hospital