Clinical trials: Cancer Associated Pain
Cancer Pain, Opioid Use
Early Treatment With Invasive Technique in Cancer Pain Management
Background: high or moderate intensity pain hits more than a half of patients with cancer and is not adequately treated way in 1/3 of this patients.
- Trial name
- NCT05594459
- Testing
- Mini invasive analgesic technique, high opioids dosages
- Volunteers
- 76 people
- Sponsor
- Regina Elena Cancer Institute
Cancer Associated Pain
Cognitive-Behavioral Care for Port Needle Insertion
This study aims to determine the effect of the Cognitive-Behavioral Intervention Package (CBIP) applied during port catheter needle insertion on pain, anxiety, and fear levels in children aged 6-18 years diagnosed with oncology.
- Trial name
- NCT07170670
- Testing
- CBIP - Cognitive-Behavioral Intervention Package
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Birgul Erdogan
Breakthrough Cancer Pain
Instanyl® Non-Interventional Study
The aim of this study is to describe the use of Instanyl® (Intranasal fentanyl spray) in the treatment of breakthrough pain (BTP) in cancer patients by success of dose titration and distribution of dose strength.
- Trial name
- INIS (NCT01045603)
- Where
- 65 sites in Denmark, France and 5 more
- Volunteers
- 309 people
- Sponsor
- Takeda
Breakthrough Cancer Pain
A Dose Titration Study of Fentanyl Buccal Soluble Film for Breakthrough Cancer Pain in Taiwan
Primary Objective: To determine the feasible dose range of Painkyl® required for Taiwanese population. Secondary Objectives: To evaluate the efficacy of Painkyl® by calculating squared mean of pain intensity difference at 30…
- Trial name
- NCT03669263
- Testing
- Fentanyl buccal soluble film (FBSF)
- Where
- Taiwan
- Volunteers
- 36 people
- Sponsor
- Chang Gung Memorial Hospital
Breast Cancer, Cancer, Treatment-Related
Chronic Cancer Pain Management Program
The goal of this research study is to evaluate an online inter-professional pain management program for survivors of breast cancer. The main questions it aims to answer: 1.
- Conditions
- Breast Cancer, Cancer, Treatment-Related, Pain Cancer
- Trial name
- ICMP (NCT06101849)
- Testing
- I-Can-Manage-Pain after cancer (Pain Management Program)
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- Hamilton Health Sciences Corporation
Cancer, Pain
A Study to Compare the Titration Efficacy and Safety of Control-released Oxycodone and Immediate-released Oxycodone in Patients With Moderate to Severe Cancer Pain
This study is to evaluate the efficacy and safety of a titration method by selects 10 mg control-released (CR) oxycodone tablet as background drug in combined with immediate-released (IR) oxycodone, compared to conventional…
- Trial name
- NCT03176199
- Testing
- Oxycodone
- Where
- 4 sites in Taiwan
- Volunteers
- 30 people
- Sponsor
- Taiwan Mundipharma Pharmaceuticals Ltd.
Opioid-Induced Constipation
Efficacy and Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation
The purpose of this study is to evaluate the safety and efficacy of CB-5945 for the treatment of opioid-induced constipation (OIC)in adults taking opioid therapy for chronic non-cancer pain.
- Trial name
- NCT01901328
- Testing
- CB-5945
- Volunteers
- 49 people
- Sponsor
- Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Pain, Pancreatic Adenocarcinoma
High Intensity Focused Ultrasound Tumor Treatment for Pancreatic Cancer Pain
This is an open-label, non-randomized, single-center, therapeutic trial in patients with AJCC Stage III or IV pancreatic cancer with tumor related abdominal and/or back pain to evaluate the safety of high intensity focused…
- Conditions
- Pain, Pancreatic Adenocarcinoma, Ductal Adenocarcinoma
- Trial name
- HIFU Pancreas (NCT00637364)
- Testing
- High intensity focused ultrasound, HIFU
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- CMED HIFU Development Corporation
Opioid-Refractory Chronic Cancer-Related Pain
The Role of Coadministration of Lidocaine and Ketamine in Opioid-Refractory Chronic Cancer-Related Pain.
This is a randomized, double-blinded, placebo-controlled, cross-over trial examining the effect of a series of two weekly intravenous infusions of lidocaine 4 mg/kg and ketamine 0.2 mg/kg in patients with moderate to severe…
- Trial name
- NCT07408193
- Testing
- Lidocaine and Ketamine Infusion
- Where
- Greece
- Volunteers
- 24 people
- Sponsor
- National and Kapodistrian University of Athens
Constipation, Bowel Dysfunction
Study Of Alvimopan Drug For Treatment Of Constipation Due To Prescription Pain Medication
A multicenter study to evaluate the effectiveness and safety of multiple dosage regimens of an investigational drug for the treatment of constipation due to prescription pain medication in subjects with cancer pain.
- Trial name
- NCT00101998
- Testing
- alvimopan
- Where
- 162 sites in United States, Argentina and 24 more
- Volunteers
- 233 people
- Sponsor
- Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Carpal Tunnel Syndrome
Safety and Efficacy of Lidoderm (Lidocaine Patch 5%) in Treating Moderate to Severe Pain Associated With Carpal Tunnel Syndrome
The purpose of this study is to evaluate the analgesic efficacy and safety of the lidocaine patch 5% compared to placebo in patients with moderate to severe pain associated with carpal tunnel syndrome.
- Trial name
- NCT00266214
- Testing
- lidocaine patch 5%
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Pain
Paracetamol in Addition to WHO Step III Opioids in Chronic Cancer Pain Control
Blinded withdrawal of regular co-medication with paracetamol in chronic pain patients under strong opioids on pain control.
- Trial name
- ParOP (NCT05088876)
- Testing
- Paracetamol
- Where
- 2 sites in Switzerland
- Volunteers
- 7 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Mobile Pain Coping Skills Training, In Person Pain Coping Skills Training
Mobile Pain Coping Skills Training for Cancer Pain
Pain in cancer patients is estimated to be as high as 90% and results in physical and psychological disability. Behavioral interventions that increase patients' confidence in their ability to manage their pain have been shown to…
- Trial name
- NCT02266017
- Testing
- Pain Coping Skills Training
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- Duke University
Chronic Pain Syndrome, Sensitization, Central
Management of Chronic Non-Cancer Pain With Non-Pharmacological Therapies
A randomized controlled clinical trial will be conducted, involving a psychoeducational activity as the intervention. There will be a control group of patients with non-cancer chronic pain who will continue their usual treatment.
- Conditions
- Chronic Pain Syndrome, Sensitization, Central, Quality of Life, Patient Empowerment
- Trial name
- NCT06440668
- Testing
- Chronic Pain Management Workshop with Non-Pharmacological Therapies
- Where
- Spain
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Hospital San Juan de Dios del Aljarafe de Sevilla
Fibrocystic Disease of Breast, Fibrocystic Changes of Breast
Study for Treatment of Moderate or Severe, Periodic, "Cyclic", Breast Pain
History of clinical breast pain for at least the last six months. At least six days of moderate or severe breast pain per cycle. Fibrosis, cysts, nodules involving at least 25% of the surface of one breast.
- Conditions
- Fibrocystic Disease of Breast, Fibrocystic Changes of Breast, Fibrocystic Mastopathy, Pain
- Trial name
- NCT00237523
- Testing
- IoGen (molecular iodine)
- Where
- 39 sites in United States
- Volunteers
- 175 people
- Sponsor
- Symbollon Pharmaceuticals
Cancer Pain
Development of a Cloud-Based PRO (Patient-Reported Outcome) Management Program for Home-Based Cancer Pain Care
This study aims to develop and pilot a cloud-based Patient-Reported Outcomes (PROs) management program for home-based cancer pain patients within a hospital setting.
- Trial name
- NCT07308223
- Testing
- Proactive monitoring and patient education
- Where
- China
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Cancer Pain, Analgesic Drugs
Adequacy of Pain Treatment in Radiotherapy
Aim of the study is to evaluate adequacy of pain treatment in oncologic patients, accessing to Radiotherapy Unit
- Trial name
- NCT03550599
- Testing
- Patients accessing to Radiotherapy Unit
- Where
- Italy
- Volunteers
- 2,000 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Moderate to Severe Cancer Pain
Effects of Opioid Drugs on Sleep and Emotion in Patients With Moderate to Severe Cancer Pain
This study is a multicenter cross-sectional observational study, aiming to include approximately 200 patients aged 18-75 years who are using hydrocodone sustained-release tablets or oxycodone sustained-release tablets for pain…
- Trial name
- NCT07616648
- Testing
- No intervention
- Where
- China
- Volunteers
- 200 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Osteoarthritis, Cancer Pain
Protocol to Monitor the Neurological Development of Infants With Exposure in Utero From Birth to 15 Months in Tanezumab Clinical Studies
A4091065 is a multicenter, prospective, cohort study with enhance physical an neurodevelopmental surveillance to characterize the outcomes related to the development of infants up to the age of 15 months who were potentially…
- Conditions
- Osteoarthritis, Cancer Pain, Recurrent Low Back Pain
- Trial name
- NCT03031938
- Testing
- Investigational medical product (IMP) administered in parent study
- Where
- 6 sites in United States
- Volunteers
- 4 people
- Sponsor
- Pfizer