Clinical trials: Cancer Distress, open to volunteers
CASA Intervention, Usual Care
Beyond Psychological Distress: Implementation of a Dyadic Behavioral Intervention Targeting Neuroendocrine and mRNA Translational Pathways in Late-Stage Breast Cancer
Specific Aim 1: Determine the effect of CASA on psychological distress (primary outcome) and on neuroendocrine, inflammatory, and translational control measures (secondary and exploratory outcomes) in LSBC-PR patients and…
- Trial name
- Beyond ID (NCT07828288)
- Testing
- The Caregivers-Patients Support to Cope with Advanced Cancer (CASA) is a five-session, manualized, meaning-centered psychotherapy developed for Puerto Rican patients and caregivers coping with advance, Control Condition. Includes CBT as the primary treatment approach for cancer patients and it is considered the usual care approach in these clinics, as well as one of the primar
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Ponce Medical School Foundation, Inc.
Caregiver Distress
Psilocybin-assisted Existential, Attachment and RelationaL (PEARL) Therapy for Caregivers of Patients With Advanced Cancer
The PEARL-C1 trial is a phase II open-label trial. Participants will receive a single high-dose (25 mg) of psilocybin in the context of Psilocybin-assisted Existential, Attachment and RelationaL (PEARL) therapy.
- Trial name
- PEARL-C1 (NCT07048743)
- Testing
- Psilocybin
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Mental Health Care, Mental Health
Mental Health CPR for Cancer Survivors
This is a parallel, two-arm interventional study comparing the Mental Health CPR behavioral intervention to standard community health education.
- Conditions
- Mental Health Care, Mental Health, Depression Anxiety Disorder
- Trial name
- MH-CPR CaS (NCT07219264)
- Testing
- Mental Health CPR, Standard Community Health Education
- Where
- Puerto Rico
- Volunteers
- 1,260 people, healthy volunteers welcome
- Sponsor
- Ponce Medical School Foundation, Inc.
Psychological Distress, Genetic Testing
Psychological Support and Psycho-Emotional Trajectories in Cancer Genetics.
Undergoing a cancer genetic testing pathway and receiving results regarding a personal or familial cancer predisposition can generate substantial, multifaceted psycho-emotional distress for patients.
- Conditions
- Psychological Distress, Genetic Testing, Hereditary Neoplastic Syndromes, Neoplasms
- Trial name
- PsyOncoGen (NCT07695506)
- Testing
- Patients undergoing their first cancer genetic testing consultation who choose to utilise the clinical psychological support offered by the unit, Patients undergoing their first cancer genetic testing consultation who choose to follow the care pathway without utilising the systematically offered clinical psychological support.
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Financial Burden, Financial Toxicity
Proactive Costs of Care Study
The Proactive Costs of Care intervention is an educational intervention designed to help patients deal with the cost of cancer care.
- Conditions
- Financial Burden, Financial Toxicity, Financial Stress, Financial Navigation
- Trial name
- PCOC (NCT07217262)
- Testing
- Educational Intervention
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Web-Based Toolkit to Improve Cancer-Related Emotional Distress and Anxiety in Rural Older Cancer Survivors
This clinical trial tests how well a web based toolkit works to improve cancer related emotional distress and anxiety in rural older cancer survivors.
- Trial name
- NCT07290543
- Testing
- Educational Intervention, Internet-Based Intervention, Interview
- Where
- United States
- Volunteers
- 578 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Caregiver, Health Care Provider
New Assessment System in Measuring Symptom Distress in Cancer Patients
This trial studies how well a new assessment system (MDASI or other MD Anderson-developed PRO instrument) works in measuring symptoms and the impact on quality of life in cancer patients.
- Conditions
- Caregiver, Health Care Provider, Malignant Neoplasm, Physician
- Trial name
- NCT00505245
- Testing
- Interview, Quality-of-Life Assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 6,500 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Cancer, Youth Cancer
Pilot Study of Mindset Moments Among Adolescent and Young Adult Cancer Survivors
The purpose of this study is to evaluate the feasibility and acceptability of the Mindset Moments™ (MM™) program in managing psychological distress and resiliency in adolescent and young adult cancer survivors.
- Conditions
- Cancer, Youth Cancer, Young Adult Cancer, Distress, Psychological
- Trial name
- NCT06732375
- Testing
- Mindset Moments
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Duke University
Childhood Cancers, Caregiver Social Support
Assessing and Addressing Health-Related Social Needs Among Families of Children With Cancer
The purpose of this study is to design Community Enhancing Resources for Childhood cAncer support (CERCA) and refine intervention procedures to target Health-related Social Needs (HRSN) in families of children with cancer.
- Conditions
- Childhood Cancers, Caregiver Social Support, Caregiver Distress, Social Needs
- Trial name
- NCT07278414
- Testing
- Community Enhancing Resources for Childhood cAncer support (CERCA)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Comparing Telephone Symptom Monitoring Interventions for Managing Symptoms and Psychological Distress During Oral Anti-Cancer Treatment
In this clinical trial, symptom monitoring (interactive voice response [IVR] is compared to automated telephone symptom management [ATSM] and telephone interpersonal counseling [TIPC]) for reducing symptom burden and…
- Trial name
- SYMON (NCT06279013)
- Testing
- Counseling, Health Education, Interview
- Where
- 34 sites in United States, Puerto Rico
- Volunteers
- 486 people, healthy volunteers welcome
- Sponsor
- NRG Oncology
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Implementation Development for Distress Screening in Pediatric Oncology (ID-DISTRESSS)
This study is being done to understand how digital strategies (e.g., electronic health record [EHR]-technology, third-party platforms, and institution-developed solutions) can be used to deliver and respond to evidence-based…
- Trial name
- NCT07908485
- Testing
- Non-Interventional Study
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Children's Oncology Group
Cancer, Healthcare Professionnals
Assessment of Cancer-related Post-traumatic Stress in Patients and Caregivers in the Year Following Diagnosis, and Identification of Their Expectations of Personalized Support - CANDYSTRESS
The impact of cancer on the lives of patients and their caregivers is undeniable. In addition to the potentially traumatic aspects (i.e., creating a very violent emotional shock) linked to the announcement of the disease and the…
- Conditions
- Cancer, Healthcare Professionnals, Caregiver Distress, Caregiver
- Trial name
- CANDYSTRESS (NCT06944262)
- Where
- 2 sites in France
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Lille University
Breast Cancer Female, Psychological Distress
The Breast Cancer Survivors and Partners Online Research Together (SUPORT) Project
Many breast cancer survivors (estimated 70% in some studies) experience clinically significant depression and/or anxiety in the months and years after finishing cancer treatments.
- Trial name
- NCT05676255
- Testing
- Cognitively-Based Compassion Training for Survivors, Cognitively-Based Compassion Training for Dyads, Health Education
- Where
- United States
- Volunteers
- 452 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Laughter Therapy, Psychological Well-being
Effect of Laughter Therapy on Breast Cancer Patients
The aim of this study is to examine the effect of laughter therapy applied to breast cancer patients before surgical intervention on distress, depression and psychological well-being of patients.
- Conditions
- Laughter Therapy, Psychological Well-being, Breast Cancer, Distress
- Trial name
- NCT07020962
- Testing
- laughter therapy, routine nursing care
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Acquired Brain Injury, Stroke/ Cerebrovascular Accident (Ischemic or Hemorrhagic)
Regulating Emotions and Behaviors After Brain Injury
After acquired brain injury (ABI), persons can experience emotional and behavioral difficulties, that can be painful both for the person and his/her family.
- Conditions
- Acquired Brain Injury, Stroke/ Cerebrovascular Accident (Ischemic or Hemorrhagic), Brain Tumor (After Recovery), Encephalitis
- Trial name
- GREMO-LCA (NCT05393492)
- Testing
- Dialectical Behavior Therapy and Radically Open dialectical behavior therapy
- Where
- France
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Oral Cancer, Psychological Distress
Develop and Evaluate An Artificial Intelligence Assisted Prehabilitation Program for Returning to Work and Cost-effectiveness Analysis in Patients With Oral Cancer
The goal of this clinical trial is to develop and evaluate an Artificial Intelligence Assisted Prehabilitation Program (AI APP) for returning to work and cost-effectiveness analysis in patients with oral cancer (OC).
- Conditions
- Oral Cancer, Psychological Distress, Communication Aids for Disabled, Physiotherapy
- Trial name
- NCT07562100
- Testing
- Prehabilitation application, Conventional physiotherapy, Scar management
- Where
- 5 sites in Taiwan
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan