Clinical trials: Cancer Distress, active
Neoplasms
Evaluation of a Program for Routine Implementation of Symptom Distress Screening and Referral in Cancer Care
This study proposes to evaluate the process and outcome of an implementation program designed to implement nurse-led symptom distress screening and referral into routine cancer care clinics.
- Trial name
- NCT05949996
- Testing
- A nurse-led symptom distress screening program
- Where
- 10 sites in Hong Kong
- Volunteers
- 2,885 people
- Sponsor
- The University of Hong Kong
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Solution-Focused Brief Therapy for Support of Psychological Distress in Adolescent and Young Adult Cancer Survivors
This clinical trial evaluates the how well a virtually delivered solution-focused brief therapy (SFBT-C) works to decrease adolescent and young adult cancer survivors' psychological distress in comparison to enhanced…
- Trial name
- NCT06941324
- Testing
- Behavioral Intervention, Best Practice, Communication Intervention
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Michigan Rogel Cancer Center
Cancer, Financial Hardship
Feasibility of a Real-world, Financial Psycho-oncology Intervention to Address Cancer-related Financial Distress
The goal of this pilot, feasibility study is to evaluate the feasibility and preliminary impact of a finance-specific psycho-oncology intervention, as well as to explore perceptions of and experiences with this financial…
- Conditions
- Cancer, Financial Hardship, Psychological Distress
- Trial name
- NCT07724041
- Testing
- Financial psycho-oncology intervention
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Alabama at Birmingham
Breast Cancer
Effect of Mandala Coloring on Anxiety, Distress, and Comfort in Breast Cancer Patients Receiving Outpatient Chemotherapy
Breast cancer patients receiving chemotherapy often experience psychological distress, anxiety, and discomfort during treatment. Non-drug supportive methods may help improve patients' well-being during chemotherapy.
- Trial name
- NCT07367269
- Testing
- Mandala Coloring
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Artvin Coruh University
Lung Neoplasms, Psychological Distress
Association of Psychological Distress in Patients With Lung Cancer
Psychological distress is a multi-factorial experience of a psychological, social, spiritual, and/or physical nature that may interfere with one's ability to cope effectively with cancer, physical symptoms and treatment.
- Conditions
- Lung Neoplasms, Psychological Distress, Prognosis Factors, Lifestyle, Healthy
- Trial name
- Life-Score (NCT06218901)
- Testing
- immunotherapy, Targeted Therapy Agent
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Shanghai Chest Hospital
Head and Neck Cancer, Body Image Disturbance
Building a Renewed ImaGe After Head & Neck Cancer Treatment (BRIGHT) Multi-Site RCT
In this multi-center randomized clinical trial, head and neck cancer (HNC) survivors with clinically significant body image distress (BID) (N=180) will be randomized to BRIGHT (a brief video tele-cognitive behavioral therapy…
- Conditions
- Head and Neck Cancer, Body Image Disturbance, Body Image, Survivorship
- Trial name
- BRIGHT (NCT05442957)
- Testing
- BRIGHT, Attention Control
- Where
- 5 sites in United States
- Volunteers
- 180 people
- Sponsor
- Medical University of South Carolina
CASA Intervention, Usual Care
Beyond Psychological Distress: Implementation of a Dyadic Behavioral Intervention Targeting Neuroendocrine and mRNA Translational Pathways in Late-Stage Breast Cancer
Specific Aim 1: Determine the effect of CASA on psychological distress (primary outcome) and on neuroendocrine, inflammatory, and translational control measures (secondary and exploratory outcomes) in LSBC-PR patients and…
- Trial name
- Beyond ID (NCT07828288)
- Testing
- The Caregivers-Patients Support to Cope with Advanced Cancer (CASA) is a five-session, manualized, meaning-centered psychotherapy developed for Puerto Rican patients and caregivers coping with advance, Control Condition. Includes CBT as the primary treatment approach for cancer patients and it is considered the usual care approach in these clinics, as well as one of the primar
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Ponce Medical School Foundation, Inc.
Bone Neoplasms, Soft Tissue Neoplasms
Stress and Anxiety Before Biopsy, After Biopsy Results, and During Treatment in Patients With Suspected Bone or Soft Tissue Cancer
This prospective observational study will follow adults who are scheduled for a clinically indicated biopsy because of a suspected solid tumor involving bone or soft tissue.
- Conditions
- Bone Neoplasms, Soft Tissue Neoplasms, Anxiety, Stress, Psychological
- Trial name
- BIOPSY-STRESS (NCT07727434)
- Testing
- Routine Diagnostic and Treatment Pathway
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul University
Head and Neck Cancer
An Oncology Nurse AI Agent to Reduce Cancer Distress During Radiotherapy
The goal of this clinical trial is to assess the effectiveness of the Digi-Coach chatbot for reducing physical and psychological distress in people undergoing radiotherapy for head and neck cancer.
- Trial name
- Digi-Coach (NCT06636188)
- Testing
- Digi-Coach Chatbot
- Where
- 2 sites in Hong Kong
- Volunteers
- 138 people
- Sponsor
- The University of Hong Kong
Solid Cancer, Bronchial Endoscopy
Impact of Interventional Endoscopy on Quality of Life in Patients With Acute Respiratory Distress Due to Tumor Compression or Obstruction of the Lower Respiratory Tract
Bronchoscopic endoscopy has shown its effectiveness and reliability for the treatment (desobstruction or prothesis) of tumor-induced bronchial obstructions, particularly in the first few weeks.
- Conditions
- Solid Cancer, Bronchial Endoscopy, Therapeutic Bronchofiberscopy
- Trial name
- ENDoRA (NCT07051161)
- Testing
- bronchoscope
- Volunteers
- 60 people
- Sponsor
- University Hospital, Grenoble
Cognitive Behavioral Therapy
Fear of Recurrence and Stopping Immunotherapy
The study includes participants experiencing distress with regard to stopping immunotherapy and will utilize cognitive-behavioral therapy to reduce fear of recurrence, depression, and anxiety and improve quality of life.
- Trial name
- NCT04761328
- Testing
- cognitive behavioral therapy
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Pittsburgh
Cancer
Effectiveness of A Multi-Component Self-Management Intervention for Anxiety and Respiratory-Related Symptoms in Patients With Lung Cancer
The study aims to examine the effectiveness of M-RDSI (Mindfulness-Respiratory Distress Symptom Intervention) in Hong Kong (HK) Chinese patients with lung cancer (LC).
- Trial name
- NCT07782710
- Testing
- M-RDSI, RDSI, Usual Care
- Volunteers
- 189 people
- Sponsor
- The Hong Kong Polytechnic University
Cancer, Psychological Distress
Support and Healing Intervention for Adolescents With a Parent Diagnosed With Cancer (SHINE)
e purpose of this study is to develop and evaluate SHINE (Support and Healing Intervention for Navigating Parental Cancer Experiences), a family-centered program designed to support adolescents whose parent has been diagnosed…
- Conditions
- Cancer, Psychological Distress, Adaptation, Psychological
- Trial name
- SHINE (NCT07751185)
- Testing
- SHINE Psychosocial Intervention, Usual Supportive Care
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Texas Southwestern Medical Center
Cancer, Psycho-Oncology
What Impact Does an Initial Psycho-oncological Contact Have on People With Cancer?
When diagnosed with cancer, patients or their relatives may, if they wish, on the recommendation of the treatment team and/or in cases of high stress, seek psycho-oncological support.
- Trial name
- PICS (NCT07544446)
- Testing
- initial psycho-oncological contact, Standard
- Where
- 5 sites in Switzerland
- Volunteers
- 148 people
- Sponsor
- Lindenhofgruppe AG
Psychological Distress (Depression, Anxiety and Stress) Cancer
Efficacy of an Integrated Psychological Interventions Combined With Ar_Rahman Listening for Reducing Psychological Distress and Enhancing Hope and Quality of Life Among Cancer Patients: A Randomized Controlled Trial
This is a randomized control trial(RCT ID:25142101) to evaluate the efficacy of psychological intervention combined with listening to surah Ar- RAhman for reducing psychological distress and improving cancer patients' hope and…
- Trial name
- NCT07833982
- Testing
- supportive psychotherapy plus QURAN recitation9Surah Ar -Rahman
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Shaheed Zulfikar Ali Bhutto Institute of Science and Technology (SZABIST) University
COVID-19 Infection, COVID-19-Associated Acute Respiratory Distress Syndrome
Study of Cord Blood Derived Mesenchymal Stem Cells for Treatment of Moderate, Severe or Critical Pneumonia
This is a phase I trial followed by a phase II randomized trial. The purpose of phase I study is the feasibility of treating patients with acute respiratory distress syndrome (ARDS) related to COVID-19 infection (COVID-19) with…
- Conditions
- COVID-19 Infection, COVID-19-Associated Acute Respiratory Distress Syndrome, Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
- Trial name
- NCT04565665
- Testing
- Best Practice, Mesenchymal Stem Cell
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- M.D. Anderson Cancer Center
Distress, Emotional, Depression, Anxiety
Training in Evidence-based Treatments in Psycho-Oncology
The goal of this research study is to train psychotherapists to administer individualized evidence-based psychotherapies in a cancer care setting to patients and caregivers with elevated levels of distress.
- Conditions
- Distress, Emotional, Depression, Anxiety, Fatigue, Pain
- Trial name
- NCT05674357
- Testing
- Individualized Evidence-Based Therapy in Cancer (Patients and Caregivers), Training in Individualized Evidence-Based Therapy in Cancer (Therapists)
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- Massachusetts General Hospital
Psychosocial Distress, Cancer
Addressing Cancer-Related Distress Through Survivorship Care in Community Oncology
The goal of this study is to understand whether providing a structured survivorship care visit at the beginning of cancer treatment is associated with changes in distress and quality of life in adults with cancer receiving…
- Trial name
- NCT07673731
- Testing
- Structured Survivorship Visit
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Ellis Medicine
Cancer Patients, Family Caregivers
A Study Comparing Two Types of Supportive Interventions for Caregivers of Patients With Cancer
The purpose of this study is to compare two types of therapy for caregivers of cancer patients: Emotion Regulation Therapy for Cancer Caregivers (ERT-C) and Cognitive Behavioral Therapy (CBT-C).
- Trial name
- NCT04802720
- Testing
- Cognitive Behavioral Therapy for Cancer Caregivers (CBT-C), Emotion Regulation Therapy for Cancer Caregivers (ERT-C)
- Where
- 5 sites in United States
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Oncology Patients
Utilization of Virtual Reality to Increase Comfort and Reduce Procedural Distress During Port Insertion Into the Body
This randomised controlled study evaluates whether virtual reality (VR) can support patient comfort and help reduce anxiety and stress during subcutaneous venous port implantation in adult oncology patients.
- Trial name
- NCT06927804
- Testing
- Virtual reality intervention, Standard Care (in control arm)
- Where
- Czechia
- Volunteers
- 60 people
- Sponsor
- University Hospital Ostrava