Clinical trials: Cancer Malnutrition
Triple Negative Breast Cancer, Vitamin D Deficiency
Impact of Vitamin D Supplementation on the Rate of Pathologic Complete Response in Vitamin D Deficient Patients
A two arm pilot study investigating the rate of pathologic complete response in patients with vitamin D deficiency and triple negative breast cancer undergoing standard neoadjuvant chemotherapy + vitamin D supplementation…
- Conditions
- Triple Negative Breast Cancer, Vitamin D Deficiency, Invasive Breast Cancer
- Trial name
- NCT04677816
- Testing
- Standard of Care Neoadjuvant Chemotherapy (NAC), Vitamin D3, Drug Diary
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Wake Forest University Health Sciences
Head and Neck Cancer, Nutrition Related Cancer
Effect of Nutritional Management on RIOM in Patients With Advanced Head and Neck Cancer
The goal of this clinical trial is to learn about the effect of nutritional management on radiation-induced oral mucositis in patients with advanced head and neck cancer during the peri-radiotherapy period .
- Conditions
- Head and Neck Cancer, Nutrition Related Cancer, Radiation-Induced Mucositis
- Trial name
- NCT05721885
- Testing
- nutrition management
- Volunteers
- 60 people
- Sponsor
- Jing Yan
Osteomalacia, Neoplasms
Catheterization to Locate Mesenchymal Tumors in Patients With Tumor-Induced Osteomalacia or Oncogenic Osteomalacia
This study will use a procedure called selective venous catheterization in patients with tumor-induced osteomalacia (TIO) or oncogenic osteomalacia (OOM) to try to locate very small tumors that produce proteins called…
- Trial name
- NCT00099762
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Nutritional Deterioration, Malignant Solid Tumor
Benefits of Nutritional Supplement in Cancer Care
This is an exploratory, open-label, 2:1 randomized controlled trial conducted across collaborating oncology clinics and extended research networks in Hong Kong.
- Conditions
- Nutritional Deterioration, Malignant Solid Tumor, Cancer Cachexia, Cancer Malnutrition
- Trial name
- NCT07869290
- Testing
- Nutrition supplement, Digital Health App Monitoring, Individualized Dietitian Consultation
- Volunteers
- 100 people
- Sponsor
- The Hong Kong Polytechnic University
Bladder Cancer, Interstitial Cystitis
The Role of Preoperative Immunonutrition on Morbidity and Immune Response After Cystectomy (INCyst Trial)
The goal of this clinical trial research study is to evaluate the impact of preoperative oral immunonutrition (IN) on post-operative complications in patients undergoing a cystectomy.
- Conditions
- Bladder Cancer, Interstitial Cystitis, Painful Bladder Syndrome, Neurogenic Bladder
- Trial name
- INCyst (NCT05726786)
- Testing
- Immunonutrition
- Where
- 4 sites in Switzerland
- Volunteers
- 232 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Malnutrition
Early Enteral Nutritional Supplementation on Patients With Oral and Oropharyngeal Cancer Undergoing Radio(Chemo)Therapy After Surgical
The target population in the present study is Chinese patients with oral and oropharyngeal cancer who plan to receive radio(chemo)therapy after surgical resection in the outpatient department.
- Trial name
- NCT03545490
- Testing
- Early nutritional intervention
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Pancreatic Cancer, Periampullary Cancer
Prehabilitation in Pancreatic Surgery
In patients with pancreatic cancer, older age, multiple comorbidities, frailty, malnutrition and poor functional status are common, especially in individuals receiving neoadjuvant chemotherapy.
- Conditions
- Pancreatic Cancer, Periampullary Cancer, Frailty Syndrome, Malnutrition
- Trial name
- PIPS (NCT06069297)
- Testing
- Multimodal Prehabilitation
- Where
- Italy
- Volunteers
- 238 people
- Sponsor
- IRCCS San Raffaele
Metastatic Gastric Cancer
Home Parenteral Nutrition for Malnourished Unresectable Stage IV Gastric Cancer
This survey is a single arm study to assess the effect of home parenteral nutrition on overall survival, cycles of salvage chemotherapy completed, side effects of salvage chemotherapy, quality of life, nutritional status…
- Trial name
- NCT03121807
- Testing
- Oliclinomel N4 Per bag 1.5 L, Oxaliplatin, 5Fluorouracil
- Where
- Taiwan
- Volunteers
- 25 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Cancer, Malnutrition
the Safety and Effectiveness of Protein Supplements on Cancer Patients With Nutritional Risk and Malnutrition
Nutritional risk and malnutrition is common in cancer patients, which is one of the significant factors affecting the overall survival, toxicity during anticancer treatment, and quality of life among patients with cancer.
- Trial name
- NCT05802381
- Testing
- protein supplement, nutrition counseling
- Volunteers
- 100 people
- Sponsor
- Peking Union Medical College Hospital
Gastrointestinal Dysfunction, Malnutrition
Postoperative GI Dysfunction and Nutrition in Malnourished Cancer Surgery Patients
This is a prospective two-center observational cohort study in adult patients undergoing major abdominal and/or pelvic oncologic surgery with pre-existing malnutrition.
- Conditions
- Gastrointestinal Dysfunction, Malnutrition, Delirium - Postoperative, Abdominal Neoplasm
- Trial name
- GIDNUT (NCT07622888)
- Testing
- Serotonin (e.g., serotonin adipinate), Standard Prokinetic Therapy (excluding serotonin)
- Where
- Russia
- Volunteers
- 120 people
- Sponsor
- Arma Ltd.
Retroperitoneal Sarcoma, Body Composition
Influence of Nutritional Status on Oncologic and Operative Outcome in Patients Operated for Retroperitoneal Sarcoma
This is a retrospective, observational study in consecutive patients operated on for primary RPS in the Institute of Oncology Ljubljana (Slovenia) between September 1999 and June 2020.
- Conditions
- Retroperitoneal Sarcoma, Body Composition, Malnutrition, Sarcopenia
- Trial name
- NCT05631379
- Testing
- Measurement of body composition with computed tomography (CT), GLIM malnutrition criteria, EWGSOP2 sarcopenia criteria
- Where
- Slovenia
- Volunteers
- 100 people
- Sponsor
- Institute of Oncology Ljubljana
Polycystic Ovary Syndrome, Healthy
Vitamin D Treatment, Pharmacogenetics and Glucose Metabolism
Background: Polycystic ovary syndrome (PCOS) is as common as 5-10% of all women in Austria. PCOS women frequently present with metabolic disturbances, hyperandrogenism and infertility. New therapy concepts are warranted.
- Conditions
- Polycystic Ovary Syndrome, Healthy, Vitamin D Deficiency
- Trial name
- NCT01721915
- Testing
- Vitamin D supplementation
- Where
- Austria
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Gastric Cancer
Perioperative Immunonutrition, Phagocytic and Bactericidal Activity of Blood Platelets in Gastric Cancer Patients
Perioperative immunonutrition in gastric cancer patients can reduce perioperative morbidity and may improve quality of their life.
- Trial name
- NCT01704664
- Testing
- Early postoperative enteral nutrition, based on standard elementary diet (Peptisorb), glutamine, oral diet enriched with arginine (Cubitan)
- Where
- Poland
- Volunteers
- 240 people
- Sponsor
- Medical University of Bialystok
Esophageal Cancer, Surgery Indication
Evaluation of the Administration of Artificial Nutrition by Feeding Jejunostomy During Neoadjuvant Treatment on Postoperative Morbidity in the Context of Esophageal or Stomach Cancer
Malnutrition is common at the time of diagnosis of esogastric cancers. However, there are no recommendations regarding preoperative nutritional support (type and duration) or on the impact of refeeding on postoperative morbidity…
- Conditions
- Esophageal Cancer, Surgery Indication, Malnourished, Neoadjuvant Treatment
- Trial name
- FREJENO (NCT07584577)
- Testing
- Enteral or parenteral nutrition
- Where
- France
- Volunteers
- 670 people
- Sponsor
- University Hospital, Bordeaux
Head and Neck Cancer
Acute and Longlasting Side Effects Caused by Radiotherapy in the Head and Neck Area
The purpose of this clinical investigation is to evaluate acute and longlasting side effects in patients undergoing radiotherapy for cancer treatment in the head and neck area.
- Trial name
- NCT00995319
- Where
- Norway
- Volunteers
- 58 people
- Sponsor
- Norwegian University of Science and Technology
Esophageal Cancer, Nutritional Deficiency
Perioperative Nutritional Support in Esophageal Cancer Patients
Upper GI malignancies often lead to involuntary weight loss and nutritional deficits. Nutritional support, both pre- and postoperatively, may improve post-operative course and reduce length of hospital stay.
- Trial name
- NEEC (NCT04190121)
- Testing
- prosure
- Where
- Greece
- Volunteers
- 110 people
- Sponsor
- THEODOROU DIMITRIOS
Vitamin D Deficiency
'Palliative-D' Vitamin D to Palliative Cancer Patients
To test the hypothesis that vitamin D treatment during 12 weeks to palliative cancer patients can decrease opioid consumption, fatigue and infectious burden and increase quality of life.
- Trial name
- Palliative-D (NCT03038516)
- Testing
- Cholecalciferol
- Where
- 3 sites in Sweden
- Volunteers
- 244 people
- Sponsor
- Region Stockholm
Acute Myeloid Leukemia, Vitamin D Deficiency
Vitamin D Effect on A Disintegrin-like And Metalloprotease Thrombospondin1 Motif 13& Interleukin 6 in Leukemia
A Disintegrin-like And Metalloprotease with Thrombospondin type 1 motif 13 (ADAMTS13) deficiency was incriminated in poor prognosis, high probability of serious complications and mortality in acute myeloid leukemia (AML)…
- Conditions
- Acute Myeloid Leukemia, Vitamin D Deficiency, ADAMTS13, Interleukin 6
- Trial name
- NCT05149339
- Testing
- Cholecalciferol 2800 I.U. ml oral drops
- Where
- Egypt
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Breast Cancer, Vitamin D Deficiency
Epidemiological Analysis of Vitamin D and Breast Cancer Risk in Saudi Arabian Women
This is an analysis of de-identified data collected from 240 Saudi Arabian women, 120 with breast cancer and 120 control women, to evalyate if vitamin D status is associated with breast cancer risk.
- Trial name
- NCT01817231
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Leukemia, Lymphoma
Nutritional Assessment Intervention to Improve Cancer-Related Fatigue
Primary Objective: 1. To use the results from this pilot study to estimate the effect size of the nutritional intervention on fatigue and caloric intake. Secondary Objectives: 1.
- Conditions
- Leukemia, Lymphoma, Fatigue
- Trial name
- NCT00507260
- Testing
- Food Record, Nutritional Consults
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- M.D. Anderson Cancer Center