Clinical trials: Cancer Pains
Menorrhagia, Dysfunctional Uterine Bleeding
Study of Conventional Laparoscopic Hysterectomy Versus Robot-Assisted Laparoscopic Hysterectomy at a Teaching Institution
Approximately 600,000 women undergo hysterectomy each year in the United States, of which 12% are laparoscopic. The most common indications for hysterectomy are: symptomatic uterine leiomyomas (40.7%), endometriosis (17.7%), and…
- Conditions
- Menorrhagia, Dysfunctional Uterine Bleeding, Leiomyoma, Pelvic Pain
- Trial name
- NCT01581905
- Testing
- Conventional Laparoscopic Hysterectomy (LH), Robot Assisted Hysterectomy
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Opioid Use, Cytokine
Cranial Electrotherapy Stimulation on Anesthetics Consumption and Postoperative Pain
Cranial electrotherapy stimulation (CES) is a non-invasive intervention to treat anxiety, depression, insomnia, and pain. But clinical studies and applications of CES in relation to acute postoperative pain are few.
- Trial name
- NCT03825471
- Testing
- electrotherapy, Opioid Anesthetics, colon cancer surgery
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Colorectal Cancer, Depression
Studying Pain and Symptom Distress in Patients With Advanced Colon Cancer, Rectal Cancer, Pancreatic Cancer, or Liver Cancer
RATIONALE: Studying a patient's understanding of his or her illness, pain, symptoms, and quality-of-life may help the study of advanced cancer and may help patients live more comfortably.
- Conditions
- Colorectal Cancer, Depression, Fatigue, Liver Cancer
- Trial name
- NCT00950144
- Testing
- medical chart review, questionnaire administration, study of socioeconomic and demographic variables
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- City of Hope Medical Center
Breast Cancer, Musculoskeletal Pain
TCM as an Adjuvant Treatment in Breast Cancer Patients
Chinese herbs can alleviates the side effects caused by conventional treatment in breast cancer patients and affects the syndrome element differentiation by altering the specific set of proteomes at specific time point of…
- Trial name
- NCT04843865
- Testing
- Chinese Herbs
- Where
- Malaysia
- Volunteers
- 30 people
- Sponsor
- Universiti Tunku Abdul Rahman
Pain, Neuropathic Pain
Assessments on Current Pain Managements in Upper Gastrointestinal Cancer Patients
Pain is one of the most common symptoms associated with cancer. The approach to pain management compresses routine pain assessments, utilizes both pharmacologic and nonpharmacologic interventions, and requires ongoing…
- Conditions
- Pain, Neuropathic Pain, Depression, Quality of Life
- Trial name
- NCT01718821
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Cheng Kung University
Lung Cancer
Educational Intervention for Patients Undergoing Surgery for Lung Cancer
The goal of this interventional study is to learn about the effect of a structured educational intervention in patients undergoing surgery for lung cancer.
- Trial name
- LUNG-SURG-EDU (NCT07614204)
- Testing
- Structured Educational Intervention, Usual Care
- Where
- Greece
- Volunteers
- 160 people
- Sponsor
- National and Kapodistrian University of Athens
Hematologic Malignancy
ONC-MM-2407: The Effect of Virtual Reality Headsets on Pain and Anxiety in the Peri and Post Bone Marrow Biopsy Period
The purpose of this research study is to see if a virtual reality (VR) headset is useful in reducing physical discomfort and anxiety experienced by patients who are scheduled to undergo a bone marrow biopsy (BMB) and/or bone…
- Trial name
- NCT07203534
- Testing
- Standard of Care, Virtual Reality intervention
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Wake Forest University Health Sciences
Cachexia, Depression
Computerized Questionnaires in Assessing Symptoms, Pain, Depression, and Physical Function in Patients With Metastatic and/or Advanced Locoregional Cancer
RATIONALE: A computer-based system for assessing symptoms may be effective for patients with metastatic or advanced cancer. PURPOSE: This clinical trial is studying how well computerized questionnaires work in assessing symptoms…
- Conditions
- Cachexia, Depression, Pain, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00972634
- Testing
- computer-assisted intervention, questionnaire administration, assessment of therapy complications
- Where
- Norway
- Volunteers
- 1,051 people
- Sponsor
- Norwegian University of Science and Technology
Neurofibromatosis 1
Efficacy of Skin Cooling in Reducing Pain Associated With Non-invasive Treatments of Neurofibromatosis Type 1 Cutaneous Neurofibromas
This study will evaluate the effectiveness of skin cooling in increasing tolerability of four treatments in Neurofibromatosis Type 1 Cutaneous Neurofibromas.
- Trial name
- NCT06132165
- Testing
- Deoxycholic Acid, Polidocanol, 1064nm Nd:YAG laser
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Massachusetts General Hospital
Post-mastectomy Pain Syndrome, Chronic Post-surgical Pain
Perioperative Pregabalin and Lidocaine to Reduce Chronic Breast Cancer Pain
Breast tissue and the areas surrounding the breast contain many small to medium-sized nerves. During surgery on the breast, these nerves can be inadvertently cut or damaged.
- Trial name
- PLAN (NCT02240199)
- Testing
- Intraoperative Intravenous Lidocaine Infusion, Perioperative Pregabalin
- Where
- 2 sites in Canada
- Volunteers
- 100 people
- Sponsor
- McMaster University
Cancer, Mindfulness-based Intervention
Effects of a Second-generation Mindfulness-based Intervention on Quality of Life, Pain Management, and Psycho-spiritual Wellbeing in Cancer Patients: A Randomised Controlled Trial
Background This study explores the effectiveness of Meditation Awareness Training (MAT), a second-generation mindfulness-based intervention, in enhancing quality of life, pain management, and psycho-spiritual wellbeing among…
- Conditions
- Cancer, Mindfulness-based Intervention, Meditation, Psychological Well-Being
- Trial name
- NCT06695234
- Testing
- Meditation Awareness Training
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- University of Derby
Hypercalcemia of Malignancy, Lung Cancer
Zoledronate in Treating Patients With Solid Tumors That Have Spread to the Bone
RATIONALE: Zoledronate may help to relieve some of the symptoms caused by bone metastases. It is not yet known if zoledronate is more effective than no further therapy in relieving symptoms of bone metastases or preventing…
- Conditions
- Hypercalcemia of Malignancy, Lung Cancer, Metastatic Cancer, Pain
- Trial name
- NCT00003884
- Testing
- zoledronic acid, quality-of-life assessment
- Where
- 55 sites in United States
- Volunteers
- 600 people
- Sponsor
- Novartis
Breast Cancer, Lung Cancer
Pillars4Life Trial
This study aims to explore whether cancer patients can benefit from completing the Pillars4Life online coping program. This randomized control trial will have half its subject completing the program and the other half receiving…
- Conditions
- Breast Cancer, Lung Cancer, Esophageal Cancer, Colon Cancer
- Trial name
- Pillars4Life (NCT02465892)
- Testing
- Pillars4Life
- Where
- United States
- Volunteers
- 284 people
- Sponsor
- Duke University
Breast Cancer, Arthralgia
Observational Study to Evaluate Mechanisms of Aromatase Inhibitor Associated Musculoskeletal Symptoms
Early stage hormone receptor positive breast cancer is typically treated with adjuvant endocrine therapy in order to decrease risk of breast cancer recurrence and to improve overall survival from the disease.
- Trial name
- NCT02118636
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Lynn Henry
Bladder Neoplasm, Prostate Neoplasm
Pre-Operative Single Shot Rectus Sheath Block
Objectives The primary objective is to demonstrate that in patients undergoing major urologic surgery, Patient Controlled Analgesia (PCA) opioid consumption in the first 24 hours after surgery will be significantly less in…
- Conditions
- Bladder Neoplasm, Prostate Neoplasm, Pelvic Neoplasm, Urologic Neoplasms
- Trial name
- NCT03458598
- Testing
- Rectus sheath block, Bilateral rectus sheath catheter, Patient controlled opioid analgesia (PCA)
- Where
- Canada
- Volunteers
- 49 people
- Sponsor
- University of Alberta
Pain, Cancer
Treatment of Breakthrough Pain in Opioid Tolerant Cancer Patients
The purpose of this study is to evaluate the safety and tolerability of OraVescent fentanyl when used long-term to relieve breakthrough pain in opioid tolerant cancer patients.
- Trial name
- NCT00105287
- Testing
- OraVescent fentanyl (OVF)
- Where
- 26 sites in United States
- Volunteers
- 100 people
- Sponsor
- Cephalon
Colon Cancer, Rectal Cancer
The Effect of Dexmedetomidine on Postoperative Analgesia
The purpose of this study is to determine whether additional Dexmedetomidine to patient controlled analgesia can reduce fentanyl consumption.
- Trial name
- NCT01373021
- Testing
- Fentanyl, Dexmedetomidine
- Where
- South Korea
- Volunteers
- 95 people
- Sponsor
- Seoul National University Hospital
Sickle Cell Disease, Virtual Reality
Role of Virtual Reality (VR) in Patients With Sickle Cell Disease (SCD)
Patients with sickle cell disease (SCD) and cancer often have complicated courses while hospitalized and often deal with pain, anxiety and depression.
- Conditions
- Sickle Cell Disease, Virtual Reality, Anxiety, Depression
- Trial name
- NCT03387033
- Testing
- Relaxation response and virtual reality (VR) session
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Duke University
Ischemic Stroke, Brain Tumor
Confounding Factors in the Detection of Intracranial Hemorrhage With the Infrascanner
The investigators prospectively want to use the Infrascanner in patients with ischemic stroke, patients with brain surgery, patients with brain tumors, patients with intracranial hemorrhage and patients with a normal CT scan of…
- Conditions
- Ischemic Stroke, Brain Tumor, Brain Surgery, Intracranial Hemorrhage
- Trial name
- NCT02809651
- Testing
- Infrascanner
- Where
- Belgium
- Volunteers
- 89 people
- Sponsor
- Ziekenhuis Oost-Limburg
Hematopoietic and Lymphoid System Neoplasm, Malignant Solid Neoplasm
Methylene Blue Mouthwash for the Treatment of Oral Mucositis Pain in Patients With Cancer
This phase III trial compares the effect of methylene blue mouthwash to standard of care mouthwash for the treatment of oral mucositis pain in patients with cancer.
- Conditions
- Hematopoietic and Lymphoid System Neoplasm, Malignant Solid Neoplasm, Stomatitis
- Trial name
- NCT05878405
- Testing
- Anti-inflammatory/Antimicrobial/Analgesic Aqueous Mouth Rinse, Methylene Blue Oral Rinse
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Mayo Clinic
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